Imaging of fatty tumors: appearance of subcutaneous lipomas in optoacoustic images.

Abstract:

:A wide variety of subcutaneous soft-tissue masses may be seen in clinical practice. Clinical examination based on palpation alone is often insufficient to identify the nature and exact origin of the mass, in which case imaging is necessary. We used handheld multispectral optoacoustic imaging technology (MSOT) in a proof-of-principle study to image superficial fatty tumors and compare the images with diagnostic ultrasound. Fatty tumors were clearly visualized by MSOT and exhibited a spectral signature which differed from normal fatty tissue or muscle tissue. Our findings further indicated that MSOT offers highly complementary contrast to sonography. Based on the performance achieved, we foresee a promising role for MSOT in the diagnosis and evaluation of subcutaneous soft-tissue masses. Picture: Pseudo-color representation of a cross-sectional multi-spectral optoacoustic slice through a subcutaneous lipoma. Multi-spectral information is encoded in color. The lipoma can clearly be distinguished from the surrounding tissue based on its color. Scalebar 1 cm.

journal_name

J Biophotonics

journal_title

Journal of biophotonics

authors

Buehler A,Diot G,Volz T,Kohlmeyer J,Ntziachristos V

doi

10.1002/jbio.201600274

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

983-989

issue

8

eissn

1864-063X

issn

1864-0648

journal_volume

10

pub_type

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