解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Further cytochemical studies on the ultrastructural localization of 5'-nucleotidase in the rat retina have revealed activity to be associated with the complex synapses formed by the rod spherules of the receptors and the bipolar and horizontal cell processes. Activity was also seen on the axolemma of receptor fibers. ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90196-9
更新日期:1984-04-01 00:00:00
abstract::In an attempt to evaluate the cellular organization and efferent projections of the nucleus tegmenti pedunculopontinus pars compacta, several experiments were performed in the rat. From measurements of neurons in the nucleus tegmenti pedunculopontinus pars compacta in Nissl-stained sections, the nucleus was observed t...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90204-5
更新日期:1984-04-01 00:00:00
abstract::Neurons of the efferent vestibular system were investigated in the cat using retrograde axonal transport of horseradish peroxidase and fluorescent retrograde double labelling techniques. The number of efferent neurons was clearly higher than previously reported. A three dimensional reconstruction of the location of th...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90200-8
更新日期:1984-04-01 00:00:00
abstract::The pontine projection of the flocculus and adjacent ventral paraflocculus was investigated with antegrade and retrograde axonal tracer techniques. Injections of horseradish peroxidase into the floccular complex revealed subsets of labeled neurons in the nucleus reticularis tegmenti pontis, the nucleus raphe pontis an...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90049-6
更新日期:1984-03-01 00:00:00
abstract::The distribution of neuropeptide Y immunoreactive cell bodies in relation to various types of catecholamine-containing cell bodies in the rat brain was analyzed immunohistochemically using antisera to tyrosine hydroxylase, dopamine beta-hydroxylase and phenylethanolamine N-methyltransferase. Coexistence of the peptide...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90036-8
更新日期:1984-02-01 00:00:00
abstract::Immunohistochemical methods were used to characterize the distribution of staining for leucine enkephalin-like and methionine enkephalin-like immunoreactivities in the telencephalon of Caiman crocodilus. Very similar distributions of both leucine enkephalin-like and methionine enkephalin-like immunoreactivity were obs...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90028-9
更新日期:1984-02-01 00:00:00
abstract::The electrical activity of 132 neurons located in the inhibitory area of the medullary reticular formation, namely, in the medial aspects of the nucleus reticularis gigantocellularis, magnocellularis and ventralis has been recorded in precollicular decerebrate cats during sinusoidal displacement of the neck. This was ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90038-1
更新日期:1984-02-01 00:00:00
abstract::The substantia nigra and ventral tegmental area of the rat were examined by retrograde transport methods to determine the topography and collateralization patterns of projections to cortex and certain subcortical sites. The topographical relationships between cells and their terminal fields were confirmed and clarifie...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90034-4
更新日期:1984-02-01 00:00:00
abstract::The effects of L-glutamate on the potency of kainate for stimulating guanosine 3',5'-cyclic monophosphate (cyclic GMP) accumulation and for killing neurones in incubated slices of immature (8-day) and adult rat cerebellum were investigated. L-glutamate did not potentiate the cyclic GMP responses to kainate in either t...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90218-5
更新日期:1984-01-01 00:00:00
abstract::Changes in the amplitude of the calcium inward current caused by intracellular administration of tolbutamide (an inhibitor of the cyclic AMP-dependent protein kinase activity) or catalytic subunits of cAMP-dependent protein kinases from rabbit myocardium were studied on internally perfused nerve cells of the snail, He...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90229-x
更新日期:1984-01-01 00:00:00
abstract::The distribution of several neuropeptides (vasoactive intestinal polypeptide, cholecystokinin octapeptide, substance P, neurotensin, methionine-enkephalin and somatostatin) in the hippocampal formation has been studied with immunocytochemical techniques. Numerous vasoactive intestinal polypeptide, cholecystokinin-octa...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90214-8
更新日期:1984-01-01 00:00:00
abstract::Purkinje cell maturation during thyroxine-induced metamorphosis in premetamorphic bullfrog tadpoles was studied using electron microscopy and Golgi (silver-impregnated) preparations. Cerebella from tadpoles were examined following 1, 2, or 3 weeks of thyroxine treatment. Particular attention was paid to possible diffe...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90219-7
更新日期:1984-01-01 00:00:00
abstract::Exposure of rats to smoke from one cigarette caused local oedema due to a marked increased in vascular permeability from the epiglottis down to bronchioli, as indicated by extravasation of Evans blue in the airway mucosa. The cigarette smoke-induced extravasation of Evans blue was still present after removal of the ta...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90117-3
更新日期:1983-12-01 00:00:00
abstract::The ontogeny of the cholecystokinin-8 neuron system in the lower brain stem of the rat was investigated by means of indirect immunofluorescence. Cholecystokinin-8-like immunoreactive structures first appeared in the primordium of the ventral tegmental area, ventral tegmental nucleus of Gudden and the area lateral to t...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90116-1
更新日期:1983-12-01 00:00:00
abstract::The cellular origin and degree of collateralization of the subcortical afferents to the caudate nucleus and the putamen in squirrel monkeys (Saimiri sciureus) were studied using the following combinations of fluorescent retrograde tracers: Evans blue and DAPI-Primuline, Fast blue and Nuclear yellow, True blue and Nucl...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90104-5
更新日期:1983-12-01 00:00:00
abstract::Monoclonal antibodies to rat striatal choline acetyltransferase were produced by fusion of sensitized mouse lymphocytes with murine plasmacytoma (NS1) cells. Two stable anti-choline acetyltransferase lines were established by limiting dilution cloning. Specificity of antibody was established by the following criteria:...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90229-4
更新日期:1983-11-01 00:00:00
abstract::In dissociated hypothalamic cell cultures of 16-day mouse embryos, growing in chemically defined medium, the catecholaminergic neurons were identified by autoradiography after labelling with [3H]dopamine and by immunocytochemistry with an anti-tyrosine hydroxylase antibody. Using selective inhibitors of amine transpor...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90217-8
更新日期:1983-11-01 00:00:00
abstract::We have studied the roles of nicotinic and muscarinic receptors in the acetylcholine-evoked secretion of catecholamine from guinea-pig chromaffin cells. Isolated guinea-pig chromaffin cells secrete catecholamine in response to acetylcholine, nicotine, and a variety of muscarinic agonists. Optimal concentrations of ace...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90236-1
更新日期:1983-11-01 00:00:00
abstract::In order to identify the specific targets of the septohippocampal projection in the rat, horseradish peroxidase localization at the electron microscopic level was used. Following injections of free horseradish peroxidase into the medial septum, sections of the dorsal hippocampal formation were reacted with diaminobenz...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90210-5
更新日期:1983-11-01 00:00:00
abstract::A systematic line-sampling method is described for counting and mapping myelinated axons in transverse sections of the spinal cord. Its advantages over random sampling of small areas are considered. The technique was applied to quantifying experimental weight-drop contusion injuries of cat spinal cord, from several mo...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90150-1
更新日期:1983-10-01 00:00:00
abstract::The noradrenergic nerve terminals and their vesicle populations have been subject to much ultrastructural research which has served to support and extend data from biochemical analysis and pharmacological-physiological experiments. Although a great deal of information has been collected, there are still many problems ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90132-x
更新日期:1983-10-01 00:00:00
abstract::Contraversive turning movements of the head were elicited in alert cats by unilateral electrical stimulation of the entopeduncular nucleus. To determine the relative functional importance of ascending and descending pathways activated by the stimulation, the animals were submitted to thalamocortical or midbrain lesion...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90090-8
更新日期:1983-09-01 00:00:00
abstract::Using the indirect immunofluorescence method, the distribution of substance P-like-immunoreactivity was studied in spinal cord and dorsal root ganglia of 25 human foetuses ranging from 12 to 29 weeks of gestational age. The spinal cord and dorsal root ganglia of three infants (1 day-, 2 and 4 month-old) were also inve...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90079-9
更新日期:1983-09-01 00:00:00
abstract::One week after injection of L-[35S]methionine into the dorsal motor nuclei of the guinea-pig, labelled tubulin carried down the vagal nerve by the slow phase of axonal transport was analysed by one- and two-dimensional gel electrophoresis. Transported tubulin showed a much stronger labelling of the beta-subunit. Isoel...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90283-x
更新日期:1983-08-01 00:00:00
abstract::The antidromic activation of facial nucleus montoneurones has been studied in acute experiments on cats by means of extra- and intracellular recording techniques. Time and amplitude characteristics of separate components of the antidromic action potential and the after--potentials accompanying it have been analyzed. A...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90270-1
更新日期:1983-08-01 00:00:00
abstract::The effect of cycloheximide (an inhibitor of protein synthesis) on the ionic currents through sodium and potassium channels was investigated in dialysed voltage-clamped N18 A-1 neuroblastoma cells. The cycloheximide concentration needed for half-inhibition of sodium peak conductance was about 0.5 micrograms/ml for 24 ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90174-4
更新日期:1983-07-01 00:00:00
abstract::In unanesthetized cats it has been found that pyramidal volleys elicited upon medullary pyramidal tract stimulation were capable of modifying the discharge of 41% of intracerebellar nuclear cells, via pontocerebellar systems impinging predominantly on the lateral cerebellar cortex. The incidence of responsive cells wa...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90304-4
更新日期:1983-06-01 00:00:00
abstract::Previous investigations of cortical organization in the brain of the turtle have revealed many features typical of mammalian neocortex. Recent evidence suggests that many neocortical neurons contain neuroactive peptides. The possibility that one such peptide, somatostatin, is found in the turtle brain was tested using...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90295-6
更新日期:1983-06-01 00:00:00
abstract::Synaptic terminals of the habenulo-interpeduncular axons in rat interpeduncular nucleus are demonstrated by electron-microscopic autoradiography following [3H]leucine injection into the habenula. The endings are of two types, S and crest synapses. Previous descriptions of the S synapses based on indirect identificatio...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90301-9
更新日期:1983-06-01 00:00:00
abstract::Examination of spontaneous miniature endplate potentials (MEPPs) in murine skeletal muscle has revealed that in conditions such as botulinum poisoning, during nerve terminal regeneration or in the presence of the drug 4-aminoquinoline, two types of acetylcholine release are responsible for the MEPPs. In addition to th...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90041-6
更新日期:1983-05-01 00:00:00
abstract::Dopaminergic mechanisms were analyzed in an isolated preparation of the turtle olfactory bulb. Field potentials were evoked by antidromic or orthodromic stimulation, and the effects determined of pharmacological manipulations of the bathing medium. In the presence of dopamine or a dopamine agonist, apomorphine, there ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90005-2
更新日期:1983-04-01 00:00:00
abstract::The ventral tegmental area of the rat brain has been shown to possess high densities of neurotensin- and dopamine-containing neuronal perikarya. We recently demonstrated that microinjection of neurotensin into the ventral tegmental area produces behavioral hyperactivity similar to amphetamine-induced increase in explo...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90195-1
更新日期:1983-03-01 00:00:00
abstract::The response to iontophoretic application of acetylcholine in the mouse neuroblastoma cell line N1E-115 was composed of three phases. The initial fast depolarizing phase was blocked by 10 microM d-tubocurarine, but not by 0.1 microM atropine. This phase was followed by a transient hyperpolarization which in turn was f...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90205-1
更新日期:1983-03-01 00:00:00
abstract::Changes in the excitability of the commissural path-CA1 pyramidal cell synapse were studied by varying the interval between the application of a conditioning pulse in the medial septal nucleus and a test pulse in the contralateral hippocampus in freely moving mice. The results showed that septal prestimulation results...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90067-2
更新日期:1983-01-01 00:00:00
abstract::Efferent projections of the zona incerta were examined in the rat using the autoradiographic and horseradish peroxidase methods, with special reference to the cytoarchitectonic structure of the zona incerta. Autoradiographic experiments showed that the incertofugal fiber systems reach ipsilaterally to the thalamus (la...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(82)90203-2
更新日期:1982-10-01 00:00:00
abstract::Addition of the excitatory amino acids l-glutamate, l-aspartate and their analogues kainate and N-methyl-d-aspartate to incubated slices of adult rat cerebellum led to large increases in cyclic GMP levels. The order of apparent potencies was kainate greater than N-methyl-d-aspartate greater than glutamate and aspartat...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(82)90209-3
更新日期:1982-10-01 00:00:00
abstract::Cytoplasmic pH (pH1) of crayfish lateral giant axons was monitored using antimony microelectrodes placed near septate junctions and variations of internal pH was induced by short applications of ammonium sulfate in the perfusing bath of the preparation. This treatment produced a rapid cell alkalinization followed, aft...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(82)90030-6
更新日期:1982-07-01 00:00:00
abstract::In anaesthetized albino rabbits, the cerebellar flocculus was systematically mapped with a glass microelectrode to identify the location of Purkinje cells that inhibit specific vestibulo-ocular reflex pathways. The effects of microstimulation of the flocculus Purkinje cell layer on vestibular nerve-evoked reflexes to ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(82)90024-0
更新日期:1982-07-01 00:00:00
abstract::We have re-examined in the rat the nuclear localization of the medullary catecholamine-containing cell groups (A1 and A2) and their relation to the vagal motor nuclei using a double labeling method. The vagal nuclei were defined by the retrograde transport of horseradish peroxidase applied to the cervical vagus, and n...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(82)90258-5
更新日期:1982-06-01 00:00:00
abstract::The effect of a transient increase in extracellular calcium concentration on the Schaffer collateral-commissural evoked excitatory postsynaptic potential and population spike responses of CAI pyramidal neurons was investigated using the rat in vitro hippocampal slice preparation. Brief exposure of slices (5-10 min) to...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(82)90254-8
更新日期:1982-06-01 00:00:00