听力与言语-语言病理学

行为科学

医学伦理学

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  • Testing the Limits of Sex Differences Using Variable Stress.

    abstract::Depression is a chronic disease that affects nearly twice as many women as men, and symptoms can differ by sex. Preclinical models disproportionately use male subjects and test a single behavioral endpoint immediately at the cessation of stress. We conducted variable stress in male and female mice for 6, 28, and 56 da...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2019.12.034

    authors: Johnson A,Rainville JR,Rivero-Ballon GN,Dhimitri K,Hodes GE

    更新日期:2021-02-01 00:00:00

  • High Fructose Diet Induces Sex-specific Modifications in Synaptic Respiration and Affective-like Behaviors in Rats.

    abstract::The consequences of excessive fructose intake extend beyond those of metabolic disorder to changes in emotional regulation and cognitive function. Long-term consumption of fructose, particularly common when begun in adolescence, is more likely to lead to deleterious consequences than acute consumption. These long-term...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2019.11.039

    authors: Kloster A,Hyer MM,Dyer S,Salome-Sanchez C,Neigh GN

    更新日期:2021-02-01 00:00:00

  • Histamine and corticosterone modulate Acid sensing ion channels (ASICs) dependent long-term potentiation at the mouse anterior cingulate cortex.

    abstract::Increase in proton concentration [H+] or decrease in local and global extracellular pH occurs in both physiological and pathological conditions. Acid-sensing ion channels (ASICs), belonging to the ENaC/Deg superfamily, play an important role in signal transduction as proton sensor. ASICs and in particular ASIC-1a (one...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2021.01.022

    authors: Natalia Gobetto M,González-Inchauspe Osvaldo D Uchitel C

    更新日期:2021-01-22 00:00:00

  • Gray Matter Volume Differences Between More Versus Less Resilient Adults with Chronic Musculoskeletal Pain: A Voxel-based Morphology Study.

    abstract::Resilience, a personality construct that reflects capacities to persevere, maintain a positive outlook and/or thrive despite ongoing stressors, has emerged as an important focus of research on chronic pain (CP). Although behavior studies have found more resilient persons with CP experience less pain-related dysfunctio...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2021.01.019

    authors: You B,Jackson T

    更新日期:2021-01-21 00:00:00

  • Do food odors differently influence cerebral activity depending on weight status? An electroencephalography study of implicit olfactory priming effects on the processing of food pictures.

    abstract::Attentional automatic processes and cerebral activity may differ between individuals with different weight statuses in the presence of food stimuli (e.g. odors, pictures). In the present study, we used an implicit olfactory priming paradigm to test the influence of non-attentively perceived food odors on the cerebral ...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2021.01.015

    authors: Zsoldos I,Sinding C,Godet A,Chambaron S

    更新日期:2021-01-19 00:00:00

  • Cortical Modulation of Nociception.

    abstract::Nociception is the neuronal process of encoding noxious stimuli and could be modulated at peripheral, spinal, brainstem, and cortical levels. At cortical levels, several areas including the anterior cingulate cortex (ACC), prefrontal cortex (PFC), ventrolateral orbital cortex (VLO), insular cortex (IC), motor cortex (...

    journal_title:Neuroscience

    pub_type: 杂志文章,评审

    doi:10.1016/j.neuroscience.2021.01.001

    authors: Gamal-Eltrabily M,Martínez-Lorenzana G,González-Hernández A,Condés-Lara M

    更新日期:2021-01-17 00:00:00

  • The N170 is Sensitive to Long-term (Personal) Familiarity of a Face Identity.

    abstract::The N170 is a large deflection of the human electroencephalogram (EEG), peaking at about 170 milliseconds over the occipito-temporal cortex after the sudden onset of a face stimulus. The N170 reflects perceptual awareness of a face and its onset corresponds to the emergence of reliable face-selectivity in the human br...

    journal_title:Neuroscience

    pub_type: 杂志文章,评审

    doi:10.1016/j.neuroscience.2020.12.036

    authors: Caharel S,Rossion B

    更新日期:2021-01-16 00:00:00

  • Microglia Regulate Cell Genesis in a Sex-dependent Manner in the Neonatal Hippocampus.

    abstract::Microglia, the innate immune cells of the brain, regulate brain development through many processes such as synaptic pruning, supporting cell genesis and phagocytosing living and dying cells. There are sex differences in these same developmental processes throughout the brain, thus microglia may contribute to brain sex...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.10.009

    authors: Nelson LH,Peketi P,Lenz KM

    更新日期:2021-01-15 00:00:00

  • Postweaning Enriched Environment Enhances Cognitive Function and Brain-Derived Neurotrophic Factor Signaling in the Hippocampus in Maternally Separated Rats.

    abstract::Adverse environments during early life may lead to different neurophysiological and behavioral consequences, including depression and learning and memory deficits that persist into adulthood. Previously, we demonstrated that exposure to an enriched environment during adolescence mitigates the cognitive impairment obse...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.09.058

    authors: Cordier JM,Aguggia JP,Danelon V,Mir FR,Rivarola MA,Mascó D

    更新日期:2021-01-15 00:00:00

  • Loss of Dysbindin Implicates Synaptic Vesicle Replenishment Dysregulation as a Potential Pathogenic Mechanism in Schizophrenia.

    abstract::The schizophrenia-susceptibility gene, dystrobrevin-binding protein 1 (DTNBP1), encodes the dysbindin protein and mediates neurotransmission and neurodevelopment in normal subjects. Functional studies show that DTNBP1 loss may cause deficient presynaptic vesicle transmission, which is related to multiple psychiatric d...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.10.020

    authors: Hu H,Wang X,Li C,Li Y,Hao J,Zhou Y,Yang X,Chen P,Shen X,Zhang S

    更新日期:2021-01-01 00:00:00

  • Associations Between Delay Discounting and Connectivity of the Valuation-control System in Healthy Young Adults.

    abstract::The process of valuation assists in determining if an object or course of action is rewarding. Delay discounting is the observed decay of a rewards' subjective value over time. Encoding the subjective value of rewards across a spectrum has been attributed to brain regions belonging to the valuation and executive contr...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.11.026

    authors: Loganathan K,Lv J,Cropley V,Ho ETW,Zalesky A

    更新日期:2021-01-01 00:00:00

  • Neural Representation in Visual Word Form Area during Word Reading.

    abstract::The visual word form area (VWFA) has been consistently identified as a crucial structure in visual word processing. Nevertheless, it is controversial whether the VWFA represents external visual information (e.g., case information) of visual words. To address that question, we functionally localized VWFA at the group l...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.10.040

    authors: Lu C,Li H,Fu R,Qu J,Yue Q,Mei L

    更新日期:2021-01-01 00:00:00

  • Sensory Experience Modulates Atrx-mediated Neuronal Integrity in the Mouse Retina.

    abstract::Mutation of the α-thalassemia/mental retardation syndrome X-linked protein, ATRX, causes intellectual disability and is associated with pleiotropic defects including ophthalmological abnormalities. We have previously demonstrated that Atrx deficiency in the mouse retina leads to the selective loss of inhibitory intern...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.10.030

    authors: Lagali PS,Zhao BYH,Yan K,Baker AN,Coupland SG,Tsilfidis C,Picketts DJ

    更新日期:2021-01-01 00:00:00

  • 17β-Oestradiol Attenuates the Photoreceptor Apoptosis in Mice with Retinitis Pigmentosa by Regulating N-myc Downstream Regulated Gene 2 Expression.

    abstract::Retinitis pigmentosa (RP) is a heterogeneous group of retinal degenerative diseases in which the final pathological feature is photoreceptor cell apoptosis. Currently, the pathogenesis of RP remains poorly understood and therapeutics are ineffective. 17β-Oestradiol (βE2) is universally acknowledged as a neuroprotectiv...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.11.010

    authors: Xiong YC,Chen T,Yang XB,Deng CL,Ning QL,Quan R,Yu XR

    更新日期:2021-01-01 00:00:00

  • Nuclear Factor [Erythroid-derived 2]-like 2 and Mitochondrial Transcription Factor A Contribute to Moderate-intensity Swimming Effectiveness against Memory Impairment in Young Mice Induced by Concomitant Exposure to a High-calorie Diet during the Early Li

    abstract::Increased energy food consumption during early-life has been associated with memory impairment. Swimming training has been reported to improve memory processes in rodent models. This study aimed to evaluate whether moderate-intensity swimming training counteracts learning and memory impairment in young mice fed a high...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.11.023

    authors: Jardim NS,Müller SG,Pase FM,Nogueira CW

    更新日期:2021-01-01 00:00:00

  • Chronic Ethanol Exposure Potentiates Cholinergic Neurotransmission in the Basolateral Amygdala.

    abstract::Chronic intermittent ethanol (CIE) exposure dysregulates glutamatergic and GABAergic neurotransmission, facilitating basolateral amygdala (BLA) pyramidal neuron hyperexcitability and the expression of anxiety during withdrawal. It is unknown whether ethanol-induced alterations in nucleus basalis magnocellularis (NBM) ...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.12.014

    authors: Sizer SE,Parrish BC,McCool BA

    更新日期:2020-12-29 00:00:00

  • Analgesic Efficacy of α2 Adrenergic Receptor Agonists Depends on the Chronic State of Neuropathic Pain: Role of Regulator of G Protein Signaling 4.

    abstract::The analgesic effect of alpha-2 adrenergic receptor (α2AR) agonists, which relieve chronic neuropathic pain, is highly variable among individuals. Here, we used a mouse model of spared nerve injury (SNI) to show that treatment time after the establishment of neuropathic pain was important for the variability in the an...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.12.021

    authors: Yoon SY,Roh DH,Yeo JH,Woo J,Han SH,Kim KS

    更新日期:2020-12-25 00:00:00

  • Dendritic Spine Remodeling and Synaptic Tau Levels in PS19 Tauopathy Mice.

    abstract::Synapse or dendritic spine loss is the strongest correlate of cognitive decline in Alzheimer's disease (AD), and neurofibrillary tangles (NFTs), but not amyloid-β plaques, associate more closely with transition to mild cognitive impairment. Yet, how dendritic spine architecture is affected by hyperphosphorylated tau i...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.12.006

    authors: Walker CK,Greathouse KM,Boros BD,Poovey EH,Clearman KR,Ramdas R,Muhammad HM,Herskowitz JH

    更新日期:2020-12-17 00:00:00

  • Tianeptine Enhances Energy-related Processes in the Hippocampal Non-synaptic Mitochondria in a Rat Model of Depression.

    abstract::Tianeptine (Tian) has been widely used in treating mood and anxiety disorders, and recently as a nootropic to improve cognitive performance. However, its mechanisms of action are insufficiently clear. We used a comparative proteomic approach to identify sub-proteome changes in hippocampal cytosol and non-synaptic mito...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.09.061

    authors: Perić I,Costina V,Findeisen P,Gass P,Filipović D

    更新日期:2020-12-15 00:00:00

  • Cortical and Subcortical Neural Interactions Between Trunk and Upper-limb Muscles in Humans.

    abstract::Activities of daily living require simultaneous and coordinated activation of trunk and upper-limb segments, which involves complex interlimb interaction within the central nervous system. Although many studies have reported associations between activity of trunk and limb muscles during functional tasks, evidence on c...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.10.011

    authors: Sasaki A,Milosevic M,Nakazawa K

    更新日期:2020-12-15 00:00:00

  • Towards Cell and Subtype Resolved Functional Organization: Mouse as a Model for the Cortical Control of Movement.

    abstract::Despite a long history of interrogation, the functional organization of motor cortex remains obscure. A major barrier has been the inability to measure and perturb activity with sufficient resolution to reveal clear functional elements within motor cortex and its associated circuits. Increasingly, the mouse has been e...

    journal_title:Neuroscience

    pub_type: 杂志文章,评审

    doi:10.1016/j.neuroscience.2020.07.054

    authors: Warriner CL,Fageiry SK,Carmona LM,Miri A

    更新日期:2020-12-01 00:00:00

  • Substance P-expressing Neurons in the Superficial Dorsal Horn of the Mouse Spinal Cord: Insights into Their Functions and their Roles in Synaptic Circuits.

    abstract::The tachykinin peptide substance P (SP) is expressed by many interneurons and some projection neurons in the superficial dorsal horn of the spinal cord. We have recently shown that SP-expressing excitatory interneurons in lamina II correspond largely to a morphological class known as radial cells. However, little is k...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.06.038

    authors: Polgár E,Bell AM,Gutierrez-Mecinas M,Dickie AC,Akar O,Costreie M,Watanabe M,Todd AJ

    更新日期:2020-12-01 00:00:00

  • Genetic Inactivation of Cholinergic C Bouton Output Improves Motor Performance but not Survival in a Mouse Model of Amyotrophic Lateral Sclerosis.

    abstract::Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that affects upper and lower motor neurons and leads to death a few years after symptom onset. Despite its high morbidity and mortality, its underlying pathogenic mechanisms still remain poorly understood. Although there is increasing evidence for sign...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.07.047

    authors: Konsolaki E,Koropouli E,Tsape E,Pothakos K,Zagoraiou L

    更新日期:2020-12-01 00:00:00

  • The Positional Logic of Sensory-Motor Reflex Circuit Assembly.

    abstract::Throughout his scientific career, Tom Jessell pioneered the spinal cord as a model system to study the molecular programs of neural specification, axon guidance, and connection specificity. His contributions to these fields and more broadly to that of developmental neuroscience will continue to inspire and define many...

    journal_title:Neuroscience

    pub_type: 杂志文章,评审

    doi:10.1016/j.neuroscience.2020.04.038

    authors: Balaskas N,Ng D,Zampieri N

    更新日期:2020-12-01 00:00:00

  • The Role of Task Complexity on Frontal Event-related Potentials and Evidence in Favour of the Epiphenomenal Interpretation of the Go/No-Go N2 Effect.

    abstract::It is well established that task complexity can affect both performance and brain processing. Event-related potentials (ERPs) studies have shown modulation of the well-known N2 and P3 components. However, limited information is available on the recently described frontal components associated with processing within th...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.09.042

    authors: Mussini E,Berchicci M,Bianco V,Perri RL,Quinzi F,Di Russo F

    更新日期:2020-11-21 00:00:00

  • K369I Tau Mice Demonstrate a Shift Towards Striatal Neuron Burst Firing and Goal-directed Behaviour.

    abstract::Pathological forms of the microtubule-associated protein tau are involved in a large group of neurodegenerative diseases named tauopathies, including frontotemporal lobar degeneration (FTLD-tau). K369I mutant tau transgenic mice (K3 mice) recapitulate neural and behavioural symptoms of FTLD, including tau aggregates i...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.09.023

    authors: Mo M,Jönsson ME,Mathews MA,Johnstone D,Ke YD,Ittner LM,Balleine BW,Furlong TM,Camp AJ

    更新日期:2020-11-21 00:00:00

  • Urolithin A Prevents Focal Cerebral Ischemic Injury via Attenuating Apoptosis and Neuroinflammation in Mice.

    abstract::Neuroinflammation contributes to neuronal death in cerebral ischemia. Urolithin A (UA), a gut microbial metabolite of ellagic acid, has emerged as a potential anti-inflammatory agent. However, its roles and precise mechanisms in stroke remain unknown. Here we found that UA treatment ameliorated infarction, neurologica...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.09.027

    authors: Lin XH,Ye XJ,Li QF,Gong Z,Cao X,Li JH,Zhao ST,Sun XD,He XS,Xuan AG

    更新日期:2020-11-10 00:00:00

  • Lactate Administration Reduces Brain Injury and Ameliorates Behavioral Outcomes Following Neonatal Hypoxia-Ischemia.

    abstract::Neonatal hypoxic-ischemic encephalopathy is a major cause of mortality and disability in newborns and the only standard approach for treating this condition is therapeutic hypothermia, which shows some limitations. Thus, putative neuroprotective agents have been tested in animal models. The present study evaluated the...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.09.006

    authors: Tassinari ID,Andrade MKG,da Rosa LA,Hoff MLM,Nunes RR,Vogt EL,Fabres RB,Sanches EF,Netto CA,Paz AH,de Fraga LS

    更新日期:2020-11-10 00:00:00

  • Hypoxia-inducible Factor 2α Exerts Neuroprotective Effects by Promoting Angiogenesis via the VEGF/Notch Pathway after Intracerebral Hemorrhage Injury in Rats.

    abstract::Angiogenesis after intracerebral hemorrhage (ICH) injury can effectively alleviate brain damage and improve neurological function. Hypoxia-inducible factor 2α (HIF-2α) is an important angiogenic regulator and exhibits protective effects in several neurological diseases; however, its role in ICH has not yet been report...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.07.010

    authors: Chen H,Xiao H,Gan H,Zhang L,Wang L,Li S,Wang D,Li T,Zhai X,Zhao J

    更新日期:2020-11-10 00:00:00

  • Tonically Active Neurons in the Monkey Dorsal Striatum Signal Outcome Feedback during Trial-and-error Search Behavior.

    abstract::An animal's choice behavior is shaped by the outcome feedback from selected actions in a trial-and-error approach. Tonically active neurons (TANs), presumed cholinergic interneurons in the striatum, are thought to be involved in the learning and performance of reward-directed behaviors, but it remains unclear how TANs...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.08.007

    authors: Inokawa H,Matsumoto N,Kimura M,Yamada H

    更新日期:2020-10-15 00:00:00

  • Differential Activation and Functional Plasticity of Multimodal Areas Associated with Acquired Musical Skill.

    abstract::Training of a musical skill is known to produce a distributed neural representation of the ability to perceive music and perform musical tasks. In the present study we tested the hypothesis that the audiovisual perception of music involves a wider activation of multimodal sensory and sensorimotor structures in the bra...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.08.013

    authors: Srinivasan N,Bishop J,Yekovich R,Rosenfield DB,Helekar SA

    更新日期:2020-10-15 00:00:00

  • Neuroprotective Effects of Anti-proBDNF in a Rat Photothrombotic Ischemic Model.

    abstract::Up-regulation of proBDNF in ischemic brain and the detrimental role of proBDNF on cellular survival has already been established. We propose that the up-regulated proBDNF may trigger the harmful events and evoke a secondary ischemic damage after ischemia. This study aimed to establish the neuroprotective effects of an...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.08.008

    authors: Rahman M,Luo H,Bobrovskaya L,Zhou XF

    更新日期:2020-10-15 00:00:00

  • Exposure to Auditory Feedback Delay while Speaking Induces Perceptual Habituation but does not Mitigate the Disruptive Effect of Delay on Speech Auditory-motor Learning.

    abstract::Perceiving the sensory consequences of our actions with a delay alters the interpretation of these afferent signals and impacts motor learning. For reaching movements, delayed visual feedback of hand position reduces the rate and extent of visuomotor adaptation, but substantial adaptation still occurs. Moreover, the d...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.07.041

    authors: Shiller DM,Mitsuya T,Max L

    更新日期:2020-10-15 00:00:00

  • Dual Function of Primary Somatosensory Cortex in Cognitive Control of Language: Evidence from Resting State fMRI.

    abstract::Resting state functional connectivity can be leveraged to investigate bilingual individual differences in cognitive control of language; however, thus far no report is provided on how the connectivity profiles of brain functional networks at rest point to different language control behavior in bilinguals. In order to ...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.08.032

    authors: Tabassi Mofrad F,Jahn A,Schiller NO

    更新日期:2020-10-15 00:00:00

  • Overexpression of MicroRNA-9a-5p Ameliorates NLRP1 Inflammasome-mediated Ischemic Injury in Rats Following Ischemic Stroke.

    abstract::The nucleotide oligomerization domain (NOD)-like receptor (NLR) pyrin domain-containing protein 1 (NLRP1) inflammasome has been shown to contribute to brain injury after ischemic stroke. Our previous study showed that microRNA-9a-5p (miR-9a-5p) ameliorates ischemic injury by regulating neuronal autophagy in rats subje...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.01.008

    authors: Cao Y,Zhang H,Lu X,Wang J,Zhang X,Sun S,Bao Z,Tian W,Ning S,Wang L,Cui L

    更新日期:2020-09-15 00:00:00

  • Emotional Impairments and Neuroinflammation are Induced in Male Mice Invulnerable to Repeated Social Defeat Stress.

    abstract::Prolonged stress triggers neuroinflammation, which plays a significant role in the development of depression; however, stressed people do not always suffer from depression because of individual differences in stress vulnerability. Negative cognitive bias (NCB) toward pessimistic judgment often underlies depressive epi...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.07.023

    authors: Ito N,Sasaki K,Takemoto H,Kobayashi Y,Isoda H,Odaguchi H

    更新日期:2020-09-01 00:00:00

  • Microglia Do Not Take Up Soluble Amyloid-beta Peptides, But Partially Degrade Them by Secreting Insulin-degrading Enzyme.

    abstract::Microglia play important roles in the pathogenesis of Alzheimer's disease (AD), in part, by affecting the clearance of amyloid-β (Aβ) peptides. Most studies, however, used synthetic soluble Aβ (sAβ) at higher concentrations. The exact mechanisms underlying microglia-mediated clearance of physiological sAβ at very low ...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.07.020

    authors: Fu H,Liu B,Li L,Lemere CA

    更新日期:2020-09-01 00:00:00

  • Estrogen-dependent MicroRNA-504 Expression and Related Baroreflex Afferent Neuroexcitation via Negative Regulation on KCNMB4 and KCa1.1 β4-subunit Expression.

    abstract::Large conductance of Ca2+-activated K+ channel (KCa1.1) plays an inhibitory role in neuroexcitation. However, the expression of KCNMB4/β4-subunit in the nodose ganglia (NG) and nucleus tractus solitarius (NTS), and its effect and regulation on baroreflex afferent function at post-transcriptional level of female rats r...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.07.003

    authors: Feng Y,Liu Y,Cao PX,Sun X,Li KX,Li XY,Liu L,Wang HD,Cui CP,Xiong X,Zhang HC,Qiao GF,Li BY

    更新日期:2020-08-21 00:00:00

  • Functional Compensation and Mechanism of Choline Acetyltransferase in the Treatment of Cognitive Deficits in Aged Dementia Mice.

    abstract::Choline acetyltransferase (ChAT) synthesizes the neurotransmitter acetylcholine (Ach). Exogenous supplementation with ChAT can functionally compensate for decreased Ach levels and ameliorate memory and cognitive deficits. In this paper, the treatment efficacy of recombinant ChAT (peptide transduction domain (PTD)-ChAT...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.05.016

    authors: Zhu Z,Zhang L,Cui Y,Li M,Ren R,Li G,Sun X,Li Q

    更新日期:2020-08-21 00:00:00

  • Reduced Midbrain Dopamine Neuron Number in the Adult Non-human Primate Brain after Fetal Radiation Exposure.

    abstract::Early gestation is a neurodevelopmental period that is especially vulnerable to environmental insult and one in which neurogenesis features prominently. Prenatal perturbation during early gestation has been linked to neuropsychiatric illnesses such as autism and schizophrenia, and severe environmental insult during th...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.07.005

    authors: Selemon LD,Begovic A

    更新日期:2020-08-21 00:00:00

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