Mechanisms regulating the activity of facial nucleus motoneurones--1. Antidromic activation.

abstract：:Zinc plays an important role in synaptic signaling in the mammalian cerebral cortex. Zinc is sequestered into presynaptic vesicles of subpopulations of glutamatergic neurons and is released by depolarization, in a calcium-dependent manner. As the majority of mechanisms that have been suggested to participate in experi...

journal_title：Neuroscience

authors： Brown CE,Dyck RH

更新日期：2003-01-01 00:00:00

abstract：:Neurones in the lumbosacral spinal cord are known to play a significant role in ejaculation. In these same areas neurones containing nitric oxide synthase (NOS) have been described. This raised the question as to whether there is a physiological role for nitrous oxide (NO) in the spinal cord in sexual behavior. We fir...

journal_title：Neuroscience

authors： Brack KE,Watkins N,Pyner S,Coote JH

更新日期：2007-12-05 00:00:00

abstract：:The performance of a cochlear implant depends on the defined interaction between afferent neurons of the spiral ganglion and the inserted electrode. Neurite outgrowth can be induced by neurotrophins such as brain-derived neurotrophic factor (BDNF) via tropomyosin kinase receptor B (TrkB). However, neurotrophin signali...

journal_title：Neuroscience

authors： Kramer B,Tropitzsch A,Müller M,Löwenheim H

更新日期：2017-08-15 00:00:00

abstract：:The presence of mRNAs in synaptic terminals and their regulated translation are important factors in neuronal communication and plasticity. Heterogeneous nuclear ribonucleoprotein (hnRNP) complexes are involved in the translocation, stability, and subcellular localization of mRNA and the regulation of its translation....

journal_title：Neuroscience

authors： Lico DT,Lopes GS,Brusco J,Rosa JC,Gould RM,De Giorgis JA,Larson RE

更新日期：2015-08-06 00:00:00

abstract：:Δ⁹ tetrahydrocannabinol (THC) and cannabidiol (CBD) are the principal psychoactive and nonpsychoactive components of cannabis. While most THC-induced behavioral effects are thought to depend on endogenous cannabinoid 1 (CB1) receptors, the molecular targets for CBD remain unclear. Here, we report that CBD and THC inhi...

journal_title：Neuroscience

authors： Xiong W,Koo BN,Morton R,Zhang L

更新日期：2011-06-16 00:00:00

abstract：:The ventral tegmental area of the rat brain has been shown to possess high densities of neurotensin- and dopamine-containing neuronal perikarya. We recently demonstrated that microinjection of neurotensin into the ventral tegmental area produces behavioral hyperactivity similar to amphetamine-induced increase in explo...

journal_title：Neuroscience

authors： Kalivas PW,Burgess SK,Nemeroff CB,Prange AJ Jr

更新日期：1983-03-01 00:00:00

abstract：:The interconnectivity between brain development and the immune system has become an area of interest for many neuroscientists. However, to date, a limited number of known immune mediators of the peripheral nervous system (PNS) have been found to influence the development of the central nervous system (CNS). FOXP3 is a...

journal_title：Neuroscience

authors： Taylor MR,Roby CR,Elziny S,Duricy E,Taylor TM,Bowers JM

更新日期：2020-08-21 00:00:00

abstract：:Perineuronal nets (PNNs) are a form of aggregate Extracellular Matrix (ECM) in the brain. Recent evidence suggests that the postnatal deposition of PNNs may play an active role in regulating neuroplasticity and, potentially, neurological disorders. Observations of high levels of PNN expression around somas, proximal d...

journal_title：Neuroscience

authors： Chu P,Abraham R,Budhu K,Khan U,De Marco Garcia N,Brumberg JC

更新日期：2018-09-15 00:00:00

abstract：:Responses to nerve stimulation were recorded with intracellular microelectrodes from neurons in the inferior mesenteric ganglion of the guinea-pig. An event was recorded which was subthreshold for a somatic action potential but which had a short rise time and a rapid initial repolarization that gave the event a small ...

journal_title：Neuroscience

authors： Coleman HA

更新日期：1987-02-01 00:00:00

abstract：:The effect of capsaicin on voltage-activated calcium currents was investigated in voltage-clamped somata of cultured adult rat dorsal root ganglion neurons. About half the neurons studied were sensitive to capsaicin, which induced an inward current at negative membrane potentials accompanied by an increase in membrane...

journal_title：Neuroscience

authors： Docherty RJ,Robertson B,Bevan S

更新日期：1991-01-01 00:00:00

abstract：:Identification of novel molecules that can induce neuronal differentiation of embryonic stem (ES) cells is essential for deciphering the molecular mechanisms of early development and for exploring cell therapy approaches. Pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal polypeptide ...

journal_title：Neuroscience

authors： Chafai M,Basille M,Galas L,Rostene W,Gressens P,Vaudry H,Gonzalez BJ,Louiset E

更新日期：2011-12-29 00:00:00

abstract：:The work of Aguayo and colleagues [Aguayo, David and Bray (1981) J. Exp. Biol. 95, 231-240] demonstrates that grafts of peripheral neural tissue are able to induce regenerative elongation of cut axons in the adult central nervous system. Elucidation of the mechanism of this response requires an understanding of the ce...

journal_title：Neuroscience

authors： Lawrence JM,Raisman G

更新日期：1987-03-01 00:00:00

abstract：:Parkinson's disease (PD) is a progressive aging disorder that affects millions worldwide, thus, disease-modifying-therapies are urgently needed. PD pathology includes α-synuclein (aSyn) accumulation as synucleinopathy. Loss of GM1 gangliosides occurs in PD brain, which is modeled in GM2 synthase transgenic mice. GM2+/...

journal_title：Neuroscience

authors： Vidal-Martinez G,Najera K,Miranda JD,Gil-Tommee C,Yang B,Vargas-Medrano J,Diaz-Pacheco V,Perez RG

更新日期：2019-07-15 00:00:00

abstract：:The enzyme choline-O-acetyltransferase catalyses the biosynthesis of acetylcholine from acetyl coenzyme A and choline and is considered as one of the best markers for cholinergic nerve endings. The distribution of this enzymatic activity was analysed during the purification of plasma membranes of purely cholinergic ne...

journal_title：Neuroscience

authors： Eder-Colli L,Amato S

更新日期：1985-06-01 00:00:00

abstract：:The uptake and transport of basic and acidic horseradish peroxidase isoenzymes was compared in the neuromuscular, visual and olfactory systems of Xenopus larvae and postmetamorphic frogs. The concentration (w/v) of the two preparations was corrected to compensate for their difference in enzymatic activity (unit/w), wh...

journal_title：Neuroscience

authors： Key B,Giorgi PP

更新日期：1987-09-01 00:00:00

abstract：:The participation of excitatory neurotransmitter systems in the basal ganglia in the initiation and propagation of limbic seizures induced by pilocarpine has been investigated in the rat. Limbic seizures (electrographic and motor) occur in rats receiving bilateral microinjections into the entopeduncular nucleus of 12....

journal_title：Neuroscience

authors： Patel S,De Sarro GB,Meldrum BS

更新日期：1988-12-01 00:00:00

abstract：:It has been suggested that not only mesostriatal but also mesolimbic pathways are involved in the degeneration of dopaminergic neurons in Parkinson's disease. Using quantitative ligand autoradiography we have investigated dopamine transporter sites in basal ganglia of patients affected by Huntington's chorea, Parkinso...

journal_title：Neuroscience

authors： Chinaglia G,Alvarez FJ,Probst A,Palacios JM

更新日期：1992-07-01 00:00:00

abstract：:Microtubule-associated protein 1B is a major constituent of the neuronal cytoskeleton during the early stages of development. This protein and its phosphorylated isoform, microtubule-associated protein 1B-P, defined by the monoclonal antibody 1B-P [Boyne L. J. et al. (1995) J. Neurosci. Res. 40, 439-450], are present ...

journal_title：Neuroscience

authors： Ma D,Connors T,Nothias F,Fischer I

更新日期：2000-01-01 00:00:00

abstract：:Many behavioral functions-including sensorimotor, attentional, memory, and emotional processes-have been associated with hippocampal processes and with dopamine transmission in the medial prefrontal cortex (mPFC). This suggests a functional interaction between hippocampus and prefrontal dopamine. The anatomical substr...

journal_title：Neuroscience

authors： Peleg-Raibstein D,Pezze MA,Ferger B,Zhang WN,Murphy CA,Feldon J,Bast T

更新日期：2005-01-01 00:00:00

abstract：:Central blockade of mineralocorticoid receptors (MRs) or angiotensin II type 1 receptors (AT1Rs) attenuates aldosterone (aldo)-salt induced hypertension. We examined the role of the subfornical organ (SFO), aldo synthesized locally in the brain, and MR and AT1R specifically in the paraventricular nucleus (PVN) in aldo...

journal_title：Neuroscience

authors： Wang HW,Huang BS,Chen A,Ahmad M,White RA,Leenen FH

更新日期：2016-02-09 00:00:00

abstract：:Spreading depolarizations are accompanied by transient changes in cerebral blood flow (CBF). In a post hoc analysis of previously studied control rats we analyzed CBF time courses after middle cerebral artery occlusion in the rat in order to test whether intra-ischemic flow, reperfusion, and different parameters of pe...

journal_title：Neuroscience

authors： Lückl J,Dreier JP,Szabados T,Wiesenthal D,Bari F,Greenberg JH

更新日期：2012-12-13 00:00:00

abstract：:Behavioural sensitization to the locomotor stimulating effects of (+)-amphetamine or quinpirole was induced in rats by intermittent drug administration. Following expression of sensitization, locomotor activity scores on day 9 were: vehicle 87 +/- 9, (+)-amphetamine 1441 +/- 227 and quinpirole 2078 +/- 214. Electrical...

journal_title：Neuroscience

authors： Muscat R,Iravani MM,Kruk ZL

更新日期：1996-12-01 00:00:00

abstract：:Light-microscope visualization in rat brain of a pattern of distribution of immunoreactivity, which included immunolabeled perikarya and beaded processes, was achieved using an immunoaffinity purified polyclonal antibody, Ab165, which recognizes the amino acid sequence, IRNLRQDRSKYY, found in the mu-opioid binding pro...

journal_title：Neuroscience

authors： Hiller JM,Zhang Y,Bing G,Gioannini TL,Stone EA,Simon EJ

更新日期：1994-10-01 00:00:00

abstract：:The aim of the present study was to determine whether thoracic spinal manipulation (SM) decreases temporal summation of back pain. The study comprised two controlled experiments including 16 and 15 healthy participants, respectively. Each study included six sessions during which painful or non-painful electrical stimu...

journal_title：Neuroscience

authors： Randoll C,Gagnon-Normandin V,Tessier J,Bois S,Rustamov N,O'Shaughnessy J,Descarreaux M,Piché M

更新日期：2017-05-04 00:00:00

abstract：:The aim of this study was to examine the role of metabotropic glutamate receptors (mGluR) in the generation of oscillatory field activity at theta frequency (4-12 Hz) in the medial septal slice prepared from rat brain. Bath application of mGluR agonists and antagonists showed that activation of mGluR1-type receptors p...

journal_title：Neuroscience

authors： Lu CB,Ouyang G,Henderson Z,Li X

更新日期：2011-03-17 00:00:00

abstract：:The immediate-early gene encoded transcription factor c-Jun is highly inducible following axotomy and therefore serves as a valuable marker in neuronal de- and regeneration. As the signals that may trigger c-Jun expression are still obscure, molecules derived from lesioned neurons and/or their targets such as growth f...

journal_title：Neuroscience

authors： Blottner D,Herdegen T

更新日期：1998-01-01 00:00:00

abstract：:Nervous system formation integrates control of cellular proliferation and differentiation and is mediated by multipotent neural progenitor cells that become progressively restricted in their developmental potential before they give rise to differentiated neurons and glial cells. Evidence from different experimental sy...

journal_title：Neuroscience

authors： Spella M,Britz O,Kotantaki P,Lygerou Z,Nishitani H,Ramsay RG,Flordellis C,Guillemot F,Mantamadiotis T,Taraviras S

更新日期：2007-06-29 00:00:00

abstract：:The resting and reflex-evoked activities of single postganglionic sympathetic neurons with axons in the right thoracic vagus were tested in chloralose-anaesthetized cats. The properties of a majority of neurons were found to be similar. Cardiac- and inspiration-related rhythmicities were present in the resting activit...

journal_title：Neuroscience

authors： Bałkowiec A,Szulczyk P

更新日期：1992-01-01 00:00:00

abstract：:Nitric oxide has been proposed to act as an intercellular messenger in central brainstem circuits controlling gastrointestinal motility. In particular, a subpopulation of preganglionic vagal neurons of the dorsal motor nucleus of the vagus have been shown to be reduced nicotinamide adenine dinucleotide phosphate(NADPH...

journal_title：Neuroscience

authors： Zheng ZL,Rogers RC,Travagli RA

更新日期：1999-05-01 00:00:00

abstract：:The pharmacological characteristics and anatomical distribution of benzodiazepine receptors in the human hippocampal formation were studied in seven cases aged 4-68 years. The pharmacology of the receptors was studied by computerized, non-linear least squares regression analysis of [3H]flunitrazepam displacement by fl...

journal_title：Neuroscience

authors： Faull RL,Villiger JW

更新日期：1988-09-01 00:00:00