Myelin-induced inhibition in a spiral ganglion organ culture - Approaching a natural environment in vitro.

abstract：:One class of spinal interneurons, the Renshaw cells, is able to discharge at very high frequencies in adult mammals. Neuronal firing at such high frequencies requires voltage-gated potassium channels to rapidly repolarize the membrane potential after each action potential. We sought to establish the pattern of express...

journal_title：Neuroscience

authors： Song ZM,Hu J,Rudy B,Redman SJ

更新日期：2006-05-12 00:00:00

abstract：:Orexins (OX), also called hypocretins, are bioactive peptides secreted from glucose-sensitive neurons in the lateral hypothalamus linking appetite, arousal and neuroendocrine-autonomic control. Here, OX-A was found to cause a slow-onset long-term potentiation of synaptic transmission (LTPOX) in the hippocampus of youn...

journal_title：Neuroscience

authors： Selbach O,Doreulee N,Bohla C,Eriksson KS,Sergeeva OA,Poelchen W,Brown RE,Haas HL

更新日期：2004-01-01 00:00:00

abstract：:After a unilateral resection of the frontal cortex in fetal cats the volume of the caudate nucleus increases while the packing density of neuronal and glial cells does not change. In the present report we address the questions of whether a similar lesion sustained neonatally or a more extensive neodecortication sustai...

journal_title：Neuroscience

authors： Loopuijt LD,Villablanca JR,Hovda DA,Huang E,Mancuso S

更新日期：1997-03-01 00:00:00

abstract：:Acute osmolar loading of cerebrospinal fluid within one lateral ventricle of dogs was examined as a cause of water extraction from the bloodstream and an increase in intracranial pressure. We have shown that a certain amount of (3)H₂O from the bloodstream enters osmotically loaded cerebrospinal fluid significantly fas...

journal_title：Neuroscience

authors： Klarica M,Miše B,Vladić A,Radoš M,Orešković D

更新日期：2013-09-17 00:00:00

abstract：:Dopamine D2-autoreceptors play a key role in regulating the activity of dopamine neurons and control the synthesis, release and uptake of dopamine. These Gi/o-coupled inhibitory receptors play a major part in shaping dopamine transmission. Found at both somatodendritic and axonal sites, autoreceptors regulate the firi...

journal_title：Neuroscience

authors： Ford CP

更新日期：2014-12-12 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) is a circadian oscillator and biological clock. Cell-to-cell communication is important for synchronization among SCN neuronal oscillators and the great majority of SCN neurons use GABA as a neurotransmitter, the principal inhibitory neurotransmitter in the adult CNS. Acting via the i...

journal_title：Neuroscience

authors： Belenky MA,Sollars PJ,Mount DB,Alper SL,Yarom Y,Pickard GE

更新日期：2010-02-17 00:00:00

abstract：:Professional Pingju actors have been shown to exhibit practice-induced plastic changes in spontaneous regional brain activity; however, whether these changes are present in resting-state regional cerebral blood flow (CBF) remains largely unclear. Here, twenty professional Pingju opera actors and 20 age-, sex-, and han...

journal_title：Neuroscience

authors： Zhao F,Zhang W,Zhu D,Wang X,Qin W,Liu F

更新日期：2020-06-01 00:00:00

abstract：:The beta-amyloid precursor protein is the precursor of the main component of senile plaques (the beta-amyloid peptide or beta/A4) found in the brain of aged humans and, in higher amounts, in the brain of Alzheimer's disease and Down's syndrome subjects. Four different forms of beta-amyloid precursor protein messenger ...

journal_title：Neuroscience

authors： Solà C,Mengod G,Probst A,Palacios JM

更新日期：1993-03-01 00:00:00

abstract：:Efr3a has been found to be involved in the functional maintenance and structural degeneration of sensory and motor nervous tissues. Our previous data have suggested that Efr3a may be associated with the initiation of the degeneration of spiral ganglion neurons (SGNs). In this study, we used Efr3a knockdown (Efr3a KD) ...

journal_title：Neuroscience

authors： Hu H,Ma Y,Ye B,Wang Q,Yang T,Lv J,Shi J,Wu H,Xiang M

更新日期：2017-01-26 00:00:00

abstract：:The ultrastructure of rat neurohypophyses incubated in vitro was studied to investigate secretion-related changes that may be intrinsic to the isolated neurohypophysis and to establish the morphological integrity of this preparation. Neurohypophyses were incubated for 2 h in an in vitro chamber in medium of low (290 m...

journal_title：Neuroscience

authors： Perlmutter LS,Hatton GI,Tweedle CD

更新日期：1984-06-01 00:00:00

abstract：:The distribution of D1 dopamine receptors was studied autoradiographically in the basal ganglia of the cat, monkey and human. These receptor binding sites were labeled directly with the D1-selective antagonist [3H]SCH 23390, and ligand-binding assays were performed concurrently. Serial- or same-action analysis permitt...

journal_title：Neuroscience

authors： Besson MJ,Graybiel AM,Nastuk MA

更新日期：1988-07-01 00:00:00

abstract：:Membrane currents evoked by iontophoretically applied acetylcholine were recorded from non-dissociated neurons of rat superior cervical ganglion using the whole-cell patch-clamp recording method. Blocking effects produced by a series of specially synthesized organic compounds, the blockers of the open channel of gangl...

journal_title：Neuroscience

authors： Skok VI,Voitenko SV,Kurenniy DE,Brovtsyna NB,Gmiro VE,Kertcer SL

更新日期：1995-08-01 00:00:00

abstract：:The roles of the central noradrenergic and serotonergic system in the activity-dependent regulation of ocular dominance plasticity have been a contentious issue. Using c-Fos activity mapping, we have developed a new, straightforward method to measure the strength of ocular dominance plasticity: the number of c-Fos-imm...

journal_title：Neuroscience

authors： Nakadate K,Imamura K,Watanabe Y

更新日期：2013-04-03 00:00:00

abstract：:The sodium-activated potassium channel Slack (Slo2.2) is widely expressed in central and peripheral neurons where it is supposed to shape firing properties important for neuronal excitability. Slack activity is enhanced by interaction with the Fragile-X-Mental-Retardation-Protein (FMRP) and loss of FMRP leads to decre...

journal_title：Neuroscience

authors： Bausch AE,Ehinger R,Straubinger J,Zerfass P,Nann Y,Lukowski R

更新日期：2018-08-01 00:00:00

abstract：:In the current study we analyzed the input-output relations in the entorhinal-dentate-hippocampal system, a major network involved in long-term memory. In anesthetized guinea pigs, the system was driven by activation of perforant path neurons in the entorhinal cortex (ENT), via presubicular fibers directly stimulated ...

journal_title：Neuroscience

authors： Bartesaghi R,Migliore M,Gessi T

更新日期：2006-09-29 00:00:00

abstract：:Light and electron microscopic immunocytochemical methods were used to study the distribution and the morphology of substance P-positive fibers and axon terminals in the dorsal column nuclei of rats and cats, and to determine whether they are part of an ascending input to these nuclei. In rats, substance P-positive fi...

journal_title：Neuroscience

authors： Conti F,De Biasi S,Giuffrida R,Rustioni A

更新日期：1990-01-01 00:00:00

abstract：:Post-traumatic syringomyelia (PTS) is a serious neurological disorder characterized by fluid filled cavities that develop in the spinal cord. PTS is thought to be caused by an imbalance between fluid inflow and outflow in the spinal cord, but the underlying mechanisms are unknown. The ion channel Kir4.1 plays an impor...

journal_title：Neuroscience

authors： Najafi E,Stoodley MA,Bilston LE,Hemley SJ

更新日期：2016-03-11 00:00:00

abstract：:Abacus-based mental calculation (AMC) activates the frontoparietal areas largely overlapping with the working memory (WM) network. Given the critical role of WM in cognition, how to improve WM capability has attracted intensive attention in past years. However, it is still unclear whether WM could be enhanced by AMC t...

journal_title：Neuroscience

authors： Dong S,Wang C,Xie Y,Hu Y,Weng J,Chen F

更新日期：2016-09-22 00:00:00

abstract：:The transition from multipotent neural stem cells (NSCs) to terminally differentiated neurons is a multistep process, and the transition is finely regulated by transcription factors with basic helix-loop-helix (bHLH) motifs. Melatonin is an endogenous neurohormone with profound neurotrophic and neuroprotective effects...

journal_title：Neuroscience

authors： Li X,Chen X,Zhou W,Ji S,Li X,Li G,Liu G,Wang F,Hao A

更新日期：2017-11-19 00:00:00

abstract：:Long-term treatment with diazepam, a full allosteric modulator of the GABA(A) receptor, results in tolerance to its anticonvulsant effects, whereas an equipotent treatment with the partial allosteric modulator imidazenil does not produce tolerance. Use of subunit-specific antibodies linked to gold particles allowed an...

journal_title：Neuroscience

authors： Pesold C,Caruncho HJ,Impagnatiello F,Berg MJ,Fritschy JM,Guidotti A,Costa E

更新日期：1997-07-01 00:00:00

abstract：:The alpha- and beta-stereoisomers of kainate correspond sterically to the L- and D-isomers of glutamate. Alpha-Kainate is a potent excitant at a specific membrane receptor site (kainate receptor). Beta-Kainate has been proposed as a functional N-methyl-D-aspartate antagonist in vivo. Because of the structural similari...

journal_title：Neuroscience

authors： Turski L,Klockgether T,Schwarz M,Sontag KH,Meldrum BS

更新日期：1987-01-01 00:00:00

abstract：:While chronic pain is a main symptom in endometriosis, the underlying mechanisms and effective therapy remain elusive. We developed an animal model enabling the exploration of ectopic endometrium as a source of endometriosis pain. Rats were surgically implanted with autologous uterus in the gastrocnemius muscle. Withi...

journal_title：Neuroscience

authors： Alvarez P,Chen X,Hendrich J,Irwin JC,Green PG,Giudice LC,Levine JD

更新日期：2012-12-06 00:00:00

abstract：:We have recently shown that isolated neuronal growth cones from developing rat forebrain possess an appreciable activity of adenylate cyclase, producing cyclic adenosine monophosphate, which can be stimulated by various neurotransmitter receptor agonists and by forskolin [Lockerbie R. O., Hervé D., Blanc G., Tassin J....

journal_title：Neuroscience

authors： Lockerbie RO,Autillo-Touati A,Araud D,Seite R,Chneiweiss H,Glowinski J,Prochiantz A

更新日期：1989-01-01 00:00:00

abstract：:Localized distension of the intestine evokes an ascending excitatory reflex and a descending inhibitory reflex in the circular muscle layer. The sequential activation of these two reflexes is believed to underlie the motor pattern of peristalsis, which is responsible for the co-ordinated propulsion of intestinal conte...

journal_title：Neuroscience

authors： Tonini M,Costa M,Brookes SJ,Humphreys CM

更新日期：1996-07-01 00:00:00

abstract：:A small surgical lesion of the parietal cortex induces an increase in the expression of several messenger RNAs varying from 172 to 980% in the entire homolateral cerebral cortex, as detected by quantitative in situ hybridization histochemistry. The messenger RNAs encoding the immediate early genes of the leucine zippe...

journal_title：Neuroscience

authors： Jacobs O,Van Bree L,Mailleux P,Zhang F,Schiffmann SN,Halleux P,Albala N,Vanderhaeghen JJ

更新日期：1994-04-01 00:00:00

abstract：:The anatomical distributions and affinity states of dopamine D1 and D2 receptors were compared in the rat central nervous system using quantitative autoradiography. [3H]SCH23390 and [3H]spiperone (in the presence of 100 nM mianserin) were used to label the D1 and D2 receptors, respectively. The densities of D1 and D2 ...

journal_title：Neuroscience

authors： Richfield EK,Penney JB,Young AB

更新日期：1989-01-01 00:00:00

abstract：:Previous work had shown that nicotinic antagonists resulted in a marked up-regulation of alpha-bungarotoxin sites in chromaffin cells in culture. The present experiments were done to determine the intracellular mechanism(s) whereby nicotinic antagonists might mediate their effects on these receptors. Chromaffin cells ...

journal_title：Neuroscience

authors： Geertsen S,Afar R,Trifaró JM,Quik M

更新日期：1990-01-01 00:00:00

abstract：:Perceiving the sensory consequences of our actions with a delay alters the interpretation of these afferent signals and impacts motor learning. For reaching movements, delayed visual feedback of hand position reduces the rate and extent of visuomotor adaptation, but substantial adaptation still occurs. Moreover, the d...

journal_title：Neuroscience

authors： Shiller DM,Mitsuya T,Max L

更新日期：2020-10-15 00:00:00

abstract：:Deep brain stimulation of the anterior nucleus of the thalamus has been proposed as novel therapy to treat intractable epilepsy. To optimize this approach, we proposed to study the involvement of this nucleus in a non-human primate model of mesial temporal lobe seizure. Two macaques were implanted with one chronic ele...

journal_title：Neuroscience

authors： Sherdil A,Coizet V,Pernet-Gallay K,David O,Chabardès S,Piallat B

更新日期：2019-10-15 00:00:00

abstract：:Extensive studies have shown that a sports expert is superior to a sports novice in visually perceptual-cognitive processes of sports scene information, however the attentional and neural basis of it has not been thoroughly explored. The present study examined whether a sport expert has the attentional superiority on ...

journal_title：Neuroscience

authors： He M,Qi C,Lu Y,Song A,Hayat SZ,Xu X

更新日期：2018-05-21 00:00:00