Cell-type specific distribution of chloride transporters in the rat suprachiasmatic nucleus.

abstract：:Excitotoxicity plays an important role in the pathogenesis of developing brain injury. The neuropeptide secretoneurin (SN) has neuroprotective potential. The aim of this study was to investigate SN plasma concentrations following excitotoxicity and to evaluate the effect of SN as therapeutic strategy in excitotoxic ne...

journal_title：Neuroscience

authors： Posod A,Wechselberger K,Schmid A,Huber E,Urbanek M,Kiechl-Kohlendorfer U,Griesmaier E

更新日期：2019-07-01 00:00:00

abstract：:Synaptic vesicle recycling is a critical feature of neuronal communication as it ensures a constant supply of releasable transmitter at the nerve terminal. Physiological studies predict that vesicle recycling is rapid and recent studies with fluorescent dyes have confirmed that the entire process may occur in less tha...

journal_title：Neuroscience

authors： Palfrey HC,Artalejo CR

更新日期：1998-04-01 00:00:00

abstract：:The distribution of gene expression domains during development constitutes a novel tool for the identification of distinct brain regions. This is particularly useful in the brain of amphibians where cell migration is very limited and most neurons organize in a periventricular layer. Here we report the expression patte...

journal_title：Neuroscience

authors： González A,López JM,Sánchez-Camacho C,Marín O

更新日期：2002-01-01 00:00:00

abstract：:The development and maintenance of cocaine addiction depend heavily on learned reward-environment associations that can induce drug-seeking behavior and relapse. Understanding the mechanisms underlying these cue-induced conditioned responses is important for relapse prevention. To test whether intracellular responses ...

journal_title：Neuroscience

authors： Nygard SK,Klambatsen A,Balouch B,Quinones-Jenab V,Jenab S

更新日期：2015-02-26 00:00:00

abstract：:L-arginine, a semi-essential amino acid, can be metabolized to form a number of bioactive molecules. Nitric oxide (NO), generated by NO synthase (NOS) from L-arginine, has been strongly implicated in the aging process. Agmatine, decarboxylated arginine, regulates the production of NO and other metabolites of L-arginin...

journal_title：Neuroscience

authors： Rushaidhi M,Collie ND,Zhang H,Liu P

更新日期：2012-08-30 00:00:00

abstract：:Central blockade of mineralocorticoid receptors (MRs) or angiotensin II type 1 receptors (AT1Rs) attenuates aldosterone (aldo)-salt induced hypertension. We examined the role of the subfornical organ (SFO), aldo synthesized locally in the brain, and MR and AT1R specifically in the paraventricular nucleus (PVN) in aldo...

journal_title：Neuroscience

authors： Wang HW,Huang BS,Chen A,Ahmad M,White RA,Leenen FH

更新日期：2016-02-09 00:00:00

abstract：:Throughout rat embryogenesis we analysed the expression patterns of the three mature transcripts generated from the two calcitonin gene-related peptide genes: calcitonin, alpha-calcitonin gene-related peptide, and beta-calcitonin gene-related peptide messenger RNAs. In addition, we examined in parallel the distributio...

journal_title：Neuroscience

authors： Terrado J,Gerrikagoitia I,Domínguez L,Raldúa D,Martínez-Millán L,Sarasa M

更新日期：1999-01-01 00:00:00

abstract：:Studies in multiple species, including in post-mortem human tissue, have shown that normal aging and/or acoustic overexposure can lead to a significant loss of afferent synapses innervating the cochlea. Hypothetically, this cochlear synaptopathy can lead to perceptual deficits in challenging environments and can contr...

journal_title：Neuroscience

authors： Bharadwaj HM,Mai AR,Simpson JM,Choi I,Heinz MG,Shinn-Cunningham BG

更新日期：2019-05-21 00:00:00

abstract：:In vivo voltammetry was used to study the effects of basolateral amygdala dopamine depletion on stress-induced dopamine release in the nucleus accumbens and medial prefrontal cortex. Male Long-Evans rats received bilateral microinjections of 6-hydroxydopamine or vehicle into the basolateral amygdala. Changes in dopami...

journal_title：Neuroscience

authors： Stevenson CW,Sullivan RM,Gratton A

更新日期：2003-01-01 00:00:00

abstract：:Voltage-gated Ca2+ channels (VGCCs) play key roles in auditory perception and information processing within the inner ear and brainstem. Pharmacological inhibition of low voltage-activated (LVA) T-type Ca2+ channels is related to both age- and noise induced hearing loss in experimental animals and may represent a prom...

journal_title：Neuroscience

authors： Lundt A,Seidel R,Soós J,Henseler C,Müller R,Bakki M,Arshaad MI,Ehninger D,Hescheler J,Sachinidis A,Broich K,Wormuth C,Papazoglou A,Weiergräber M

更新日期：2019-06-15 00:00:00

abstract：:We have previously shown that voluntary exercise produces enhanced neurogenesis and long-term potentiation (LTP) in the dentate gyrus (DG) of mice in vitro. In the present experiments we show that rats given access to a running wheel (Runners) exhibit significantly more short-term potentiation and LTP with theta-patte...

journal_title：Neuroscience

authors： Farmer J,Zhao X,van Praag H,Wodtke K,Gage FH,Christie BR

更新日期：2004-01-01 00:00:00

abstract：:In the present study, we used co-culture of astrocytes from one species with neurons from a different species to examine neuritic outgrowth. We include a focus on human cells. Three types of neuron were used, including rat hippocampal dentate granule cells, rat hypothalamic neurons and human cortical neurons. To visua...

journal_title：Neuroscience

authors： van den Pol AN,Spencer DD

更新日期：2000-01-01 00:00:00

abstract：:The influence of intra-arterial injections of 5-hydroxytryptamine, histamine and prostaglandin E2 on afferent impulse activity of mesenteric nerves of small intestine was studied. In anaesthetized cats 5-hydroxytryptamine (10(-5)-10(-4) M) and histamine (10(-5)-10(-3) M) were shown to increase the impulse activity in ...

journal_title：Neuroscience

authors： Akoev GN,Filippova LV,Sherman NO

更新日期：1996-04-01 00:00:00

abstract：:The ventrolateral periaqueductal gray is implicated as a component of the neuronal network for audiogenic seizure. This implication is based on immunocytochemical labeling of the proto-oncogene, c-fos, and microinjection studies in the severe substrain of genetically epilepsy-prone rats that exhibits tonic seizures. T...

journal_title：Neuroscience

authors： N'Gouemo P,Faingold CL

更新日期：1998-05-01 00:00:00

abstract：:The molecular mechanisms underlying the response to injury in the central nervous system are incompletely understood. Many cell activation systems may be involved. Tyrosine kinase receptors and their ligands play key roles in cell activation throughout life. The Eph family of tyrosine kinase receptors/ ligands are dev...

journal_title：Neuroscience

authors： Moreno-Flores MT,Wandosell F

更新日期：1999-01-01 00:00:00

abstract：:Brainstem projections to hypoglossal motoneurons innervating the intrinsic and extrinsic muscles of the tongue were determined using the transneuronal transfer of Herpes simplex virus-1. Injections of Herpes simplex virus-1 into the intrinsic muscles of the anterior tongue, the geniohyoid and styloglossus muscles each...

journal_title：Neuroscience

authors： Travers JB,Montgomery N,Sheridan J

更新日期：1995-10-01 00:00:00

abstract：:The lurcher mutation induces Purkinje cell degeneration in heterozygous mice, and neonatal death in homozygous animals. Using the D6Mit16 Simple Sequence Length Polymorphic marker in F2 hybrids between AKR +/+ mice and B6+/Lc mice, homozygous lurcher fetuses and newborns as well as heterozygous and normal littermates ...

journal_title：Neuroscience

authors： Resibois A,Cuvelier L,Goffinet AM

更新日期：1997-09-01 00:00:00

abstract：:The hemispheric content of dopamine and its metabolites in the frontal cortex, caudatus putamen and nucleus accumbens septi was evaluated in relation to behavioral lateralization assessed by paw preference. Three groups of C3H/He mice were selected on the basis of their performance in the paw preference test (left-han...

journal_title：Neuroscience

authors： Cabib S,D'Amato FR,Neveu PJ,Deleplanque B,Le Moal M,Puglisi-Allegra S

更新日期：1995-01-01 00:00:00

abstract：:beta-Endorphin is a non-selective opioid peptide which binds mu-, delta- and putative epsilon (beta-endorphin-sensitive non-mu-, non-delta- and non-kappa(1)-)-opioid receptors. We have previously reported that beta-endorphin-produced G-protein activation is mediated by the stimulation of both mu- and putative epsilon-...

journal_title：Neuroscience

authors： Mizoguchi H,Wu HE,Narita M,Hall FS,Sora I,Uhl GR,Nagase H,Tseng LF

更新日期：2002-01-01 00:00:00

abstract：:Localization of luteotrophic hormone-releasing hormone (LHRH) was examined by immunocytochemistry in untreated male rats and rats that received an anterior hypothalamic deafferentation. Gonadotrophic function was assessed by examining testicular weight and morphology. All of the antisera used in this study were able t...

journal_title：Neuroscience

authors： Hoffman GE,Gibbs FP

更新日期：1982-01-01 00:00:00

abstract：:Capsaicin, a neurotoxin which depletes substance P from primary afferent nerve fibres, was injected systematically into adult guinea pigs. The effects of capsaicin were studied by immunohistochemistry, electron microscopy and radioimmunoassay at times from 5 min to 1 year. Within 5 min after a single injection of caps...

journal_title：Neuroscience

authors： Papka RE,Furness JB,Della NG,Murphy R,Costa M

更新日期：1984-08-01 00:00:00

abstract：:Since mild thermal stress seems to exert neuroprotection via induction of heat-shock protein 70 kDa (hsp70), we tested whether hsp70 would preserve striatal bioelectrical activity under conditions of mitochondrial impairment. Corticostriatal slices from rats that had undergone mild thermal stress were exposed to eithe...

journal_title：Neuroscience

authors： Tantucci M,Mariucci G,Taha E,Spaccatini C,Tozzi A,Luchetti E,Calabresi P,Ambrosini MV

更新日期：2009-10-20 00:00:00

abstract：:Rearing rats in isolation has been shown to produce behavioral and neurochemical alterations similar to those observed in psychoses such as schizophrenia. Also, a dysregulation in both the endocannabinoid and dopaminergic systems has been implicated in schizophrenia. The aim of this study was to determine if there are...

journal_title：Neuroscience

authors： Malone DT,Kearn CS,Chongue L,Mackie K,Taylor DA

更新日期：2008-03-03 00:00:00

abstract：:Behavioural sensitization to the locomotor stimulating effects of (+)-amphetamine or quinpirole was induced in rats by intermittent drug administration. Following expression of sensitization, locomotor activity scores on day 9 were: vehicle 87 +/- 9, (+)-amphetamine 1441 +/- 227 and quinpirole 2078 +/- 214. Electrical...

journal_title：Neuroscience

authors： Muscat R,Iravani MM,Kruk ZL

更新日期：1996-12-01 00:00:00

abstract：:The in vivo effects of [D-Pen2,D-Pen5]enkephalin, a cyclic peptide agonist with high affinity and selectivity for the delta opioid receptors, on the endogenous aluminum content of selected areas of rat brain and spinal cord were studied by means of atomic absorption spectrophotometry. Intracerebroventricular injection...

journal_title：Neuroscience

authors： Gulya K,Szikra J,Kása P

更新日期：1995-05-01 00:00:00

abstract：:Neurotrophin gene expression in adult brain varies according to physiological activity and following brain injury, suggesting a role in neuronal maintenance and plasticity. However, the exact roles and mechanisms of action of neurotrophins in the adult brain are still poorly understood. We have recently demonstrated t...

journal_title：Neuroscience

authors： Guilhem D,Dreyfus PA,Makiura Y,Suzuki F,Onteniente B

更新日期：1996-06-01 00:00:00

abstract：:Previous findings, mainly in in vitro systems, have shown that the density of vesicles and the synaptic efficacy at excitatory synapses are reduced in the absence of synapsins, despite the fact that transgenic mice lacking synapsins develop an epileptic phenotype. Here we study glutamate receptors by quantitative immu...

journal_title：Neuroscience

authors： Gylterud Owe S,Bogen IL,Walaas SI,Storm-Mathisen J,Bergersen LH

更新日期：2005-01-01 00:00:00

abstract：:GABAB receptors affect short-term signalling in various cell types. However, nothing is known about possible long-term effects on transcription. To analyse such effects in the CNS, we studied GABAB receptor-mediated gene regulation in primary cultures of cerebellar granule neurons. Transcription was followed using a c...

journal_title：Neuroscience

authors： Barthel F,Kienlen Campard P,Demeneix BA,Feltz P,Loeffler JP

更新日期：1996-01-01 00:00:00

abstract：:Similarities in cellular morphology, afferentation, efferentation, and neurotransmitter content between the internal and external parts of the pallidum and the substantia nigra pars reticulata have long been noted. Here we present evidence that the globus pallidus, entopedunucular nucleus and substantia nigra pars ret...

journal_title：Neuroscience

authors： Sousa R,Hrinya Tannery N,Lafer EM

更新日期：1990-01-01 00:00:00

abstract：:Cholecystokinin-like immunoreactivity was investigated with an indirect immunoperoxidase technique in the whole spinal cord with the light microscope and in the dorsal horn with the electron microscope. Intraparenchymal injections of colchicine were performed to allow the detection of cholecystokinin-like immunoreacti...

journal_title：Neuroscience

authors： Conrath-Verrier M,Dietl M,Tramu G

更新日期：1984-11-01 00:00:00