Abstract:
:Efferent projections of the zona incerta were examined in the rat using the autoradiographic and horseradish peroxidase methods, with special reference to the cytoarchitectonic structure of the zona incerta. Autoradiographic experiments showed that the incertofugal fiber systems reach ipsilaterally to the thalamus (lateral dorsal, central lateral, ventral lateral geniculate, parafascicular, subparafascicular and reuniens nuclei, and posterior nuclear complex), to the hypothalamus (dorsal, lateral and posterior hypothalamic areas), to the tectum (medial pretectal area, deep pretectal and pretectal nuclei, superior colliculus and periaqueductal gray) and to the midbrain tegmentum, pons and medulla oblongata (subcuneiform, cuneiform and red nuclei, nuclei of the posterior commissure and Darkschewitsch, interstitial nucleus of Cajal, pedunculopontine tegmental nucleus, oral and caudal pontine reticular nuclei, nucleus raphe magnus, gigantocellular reticular nucleus, pontine gray and inferior olivary complex). Contralaterally, incertal efferent fibers reach to the zona incerta. Cells of origin of the incertofugal fiber systems to the tectum, thalamus, tegmentum and spinal cord were examined using the retrograde horseradish peroxidase method. Cells of origin of the incertotectal pathway are located mainly in the ventral and causal parts of the zona incerta and partly in the antero-polar, dorsal and postero-polar parts. Cells projecting to the thalamus (at least to the lateral dorsal and central lateral nuclei) are situated in the ventral and caudal parts of the zona incerta, but they are rare in the other incertal structures. Cells of origin of the incertotegmental system are located mainly in the dorsal, magnocellular and caudal parts and partly in the antero- and postero-polar parts, but they are not situated in the ventral part. Cells of the magnocellular part project more caudally to the medulla oblongata and spinal cord than those of the other parts of the zona incerta. Forel's field contains many cells projecting to the tegmentum. The results provide good evidence that the cells of origin of efferent projections are topographically organized and are related to cytoarchitectonic areas within the zona incerta.
journal_name
Neurosciencejournal_title
Neuroscienceauthors
Watanabe K,Kawana Edoi
10.1016/0306-4522(82)90203-2subject
Has Abstractpub_date
1982-10-01 00:00:00pages
2389-2406issue
10eissn
0306-4522issn
1873-7544pii
0306-4522(82)90203-2journal_volume
7pub_type
杂志文章相关文献
NEUROSCIENCE文献大全abstract::Cytochrome oxidase is the terminal enzyme in the mitochondrial respiratory chain engaged in oxidative metabolism and energy production. In mammals, the holoenzyme is composed of 13 subunits encoded by both nuclear and mitochondrial genomes. The goal of the present study was to compare the effect of afferent impulse bl...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(95)00043-i
更新日期:1995-07-01 00:00:00
abstract::Icariin is derived most commonly from the traditional Chinese herb Epimedium brevicornum Maxim. Our previous studies have shown that icariin protects neurons from neurotoxic and ischemic conditions. This study aims to investigate the effect of icariin on the expression of amyloid precursor protein (APP) and the level ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2015.06.010
更新日期:2015-09-24 00:00:00
abstract::Experimental autoimmune encephalomyelitis (EAE) is a widely used animal model for the human disease multiple sclerosis (MS), a demyelinating and neurodegenerative pathology of the central nervous system. Both diseases share physiopathological and clinical characteristics, mainly associated with a neuroinflammatory pro...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2015.11.060
更新日期:2016-02-09 00:00:00
abstract::Growth-associated protein-43, an established marker of neuronal plasticity during development and in injury, was used to characterize innervation in the normal human pancreas and changes in chronic alcohol-induced pancreatitis by using light microscopic immunocytochemistry and computer-assisted image analysis. Immunos...
journal_title:Neuroscience
pub_type: 临床试验,杂志文章
doi:10.1016/0306-4522(94)90020-5
更新日期:1994-11-01 00:00:00
abstract::The neurotensin-containing projections from the retrosplenial cortex to the anterior ventral thalamus were demonstrated by electrolytic lesion studies and fluorescent retrograde tracing combined with immunocytochemistry. Three-to-five-day-old rats were used, because the immunoreactivity of neurotensin fibers in anteri...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(88)90102-9
更新日期:1988-09-01 00:00:00
abstract::The chemoanatomical organization of the visual sector of the cat's thalamic reticular nucleus (TRN)-that is at the dorsal lateral geniculate nucleus (dLGN) and at the pulvinar nucleus (Pul)-was investigated with two novel cytoarchitectonic markers. The Wisteria floribunda agglutinin (WFA) binding reaction visualized t...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2009.11.010
更新日期:2010-02-03 00:00:00
abstract::Most mammals rely on semiochemicals, such as pheromones, to mediate their social interactions. Recent studies found that semiochemicals are perceived by at least two distinct chemosensory systems: the main and accessory olfactory systems, which share many molecular, cellular, and anatomical features. Nevertheless, the...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2011.05.039
更新日期:2011-08-25 00:00:00
abstract::Central blockade of mineralocorticoid receptors (MRs) or angiotensin II type 1 receptors (AT1Rs) attenuates aldosterone (aldo)-salt induced hypertension. We examined the role of the subfornical organ (SFO), aldo synthesized locally in the brain, and MR and AT1R specifically in the paraventricular nucleus (PVN) in aldo...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2015.11.055
更新日期:2016-02-09 00:00:00
abstract::Intracellular stimulation of single propriospinal axons evoked excitatory postsynaptic potentials (EPSPs) in lumbar motoneurons. Mean EPSP amplitudes differed by two orders of magnitude when measured in different connections. After analyzing the distribution of mean amplitudes of 47 single-fiber EPSPs, two populations...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(01)00267-6
更新日期:2001-01-01 00:00:00
abstract::We have shown that transgenic transient axonal glycoprotein (TAG)/F3 mice, in which the mouse axonal glycoprotein F3/contactin was misexpressed from a regulatory region of the gene encoding the transient axonal glycoprotein TAG-1, exhibit a transient disruption of cerebellar granule and Purkinje cell development [Deve...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2003.08.025
更新日期:2004-01-01 00:00:00
abstract::The Ca(2+)-dependent release of the neurotransmitter glutamate from purified nerve terminals (synaptosomes) of the rat hippocampus was studied in a rapid perfusion apparatus. The response of the terminals was investigated with respect to the kinetics and duration of the release of endogenous glutamate upon brief and s...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(91)90417-m
更新日期:1991-01-01 00:00:00
abstract::The aim of the present work was to investigate the mechanism by which the diffusible factor nitric oxide regulates GABAA receptor function in the brain. The effect of nitric oxide on GABAA receptor function has been studied in two different neuronal preparations: rat cerebral cortex microsacs and rat cerebellum granul...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(96)00110-8
更新日期:1996-09-01 00:00:00
abstract::Since mild thermal stress seems to exert neuroprotection via induction of heat-shock protein 70 kDa (hsp70), we tested whether hsp70 would preserve striatal bioelectrical activity under conditions of mitochondrial impairment. Corticostriatal slices from rats that had undergone mild thermal stress were exposed to eithe...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2009.06.070
更新日期:2009-10-20 00:00:00
abstract::The response to iontophoretic application of acetylcholine in the mouse neuroblastoma cell line N1E-115 was composed of three phases. The initial fast depolarizing phase was blocked by 10 microM d-tubocurarine, but not by 0.1 microM atropine. This phase was followed by a transient hyperpolarization which in turn was f...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(83)90205-1
更新日期:1983-03-01 00:00:00
abstract::Migration of postmitotic neurons in the developing cortex along radial glial fiber is essential for the formation of cortical layers. Several neurological diseases are caused by defects in neuronal migration, underlining the importance of this process for brain function. Multiple molecules are involved in this process...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2015.02.025
更新日期:2015-04-30 00:00:00
abstract::A variety of neurological diseases are characterized by disturbances of the blood-brain barrier (BBB) and its transporters. We recently introduced fibroblast growth factor treated cortical organotypic slice cultures of mice as a model for in vitro studies of the blood-brain barrier and have now further characterized t...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2010.06.073
更新日期:2010-09-29 00:00:00
abstract::Clozapine, an atypical antipsychotic agent important for the treatment of schizophrenia, has marked inhibitory effects on sympathetic outflow to the thermoregulatory cutaneous circulation. In rabbits clozapine reverses ear pinna vasoconstriction induced either by administration of MDMA (3,4-methylenedioxymethamphetami...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2006.05.050
更新日期:2006-09-15 00:00:00
abstract::Nitric oxide (NO) has been long assumed to play a key role in mammalian olfaction. This was based largely on circumstantial evidence, i.e. prominent staining for nitric oxide synthase (NOS) and cyclic guanosine 3',5'-cyclic monophosphate (cGMP) or soluble guanylyl cyclase, an effector enzyme activated by NO, in local ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2008.03.003
更新日期:2008-05-15 00:00:00
abstract::Neurons in the superior paraolivary nucleus (SPON) of the rat respond to the offset of pure tones with a brief burst of spikes. Medial nucleus of the trapezoid body (MNTB) neurons, which inhibit the SPON, produce a sustained pure tone response followed by an offset response characterized by a period of suppressed spon...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2007.11.008
更新日期:2008-02-06 00:00:00
abstract::l-glutamate, an umami taste substance, is a key molecule coupled to a food intake signaling pathway. Furthermore, recent studies have unveiled new roles for dietary glutamate on gut-brain axis communication via activation of gut glutamate receptors and subsequent vagus nerve. In the present study, we mapped activation...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2011.09.003
更新日期:2011-11-24 00:00:00
abstract::In partially denervated skeletal muscle, spared motor fibres sprout, enlarging motor unit size. Neuritogenesis and sprouting are known to depend on the synaptic input to the neurons. This suggests that spared motoneuron reaction to partial muscle denervation might be controlled by primary sensory neurons which directl...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(97)00506-x
更新日期:1998-05-01 00:00:00
abstract::We have examined the basic electrophysiology and pharmacology of cells in the anterior caudal lobe (CLa) of the mormyrid cerebellum. Intracellular recordings were performed in an in vitro slice preparation using the whole-cell patch recording method. The responses of cells to parallel fiber (PF) and climbing fiber (CF...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2010.08.033
更新日期:2010-11-24 00:00:00
abstract::The occurrence of neuropeptide Y-like immunoreactivity in the adrenal gland was investigated by means of radioimmunoassay, chromatography and immunohistochemistry. The adrenal levels of neuropeptide Y-like immunoreactivity varied considerably between species with lowest amounts in the rat and highest in the cow where ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(86)90313-1
更新日期:1986-11-01 00:00:00
abstract::To examine whether dopamine modulates cortical N-methyl-D-aspartate receptor-mediated glutamate transmission, whole-cell recordings were made from identified pyramidal cells located in layers V and VI of the medial prefrontal cortex of the rat using a slice preparation. In the presence of tetrodotoxin and the absence ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(98)00604-6
更新日期:1999-01-01 00:00:00
abstract::An antisense oligodeoxynucleotide selective for the rat neuropeptide Y1 receptor gene was given into the left lateral ventricle in the experimental group of rats, whereas a missense oligodeoxynucleotide or saline was given in the control groups. Some rats were decapitated at 1-2h after the last injection of the oligod...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(00)00159-7
更新日期:2000-01-01 00:00:00
abstract::It is becoming clear that the detection and integration of synaptic input and its conversion into an output signal in cortical neurons are strongly influenced by background synaptic activity or "noise." The majority of this noise results from the spontaneous release of synaptic transmitters, interacting with ligand-ga...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2007.05.016
更新日期:2007-07-29 00:00:00
abstract::Stem cells have a number of properties, which make them excellent candidates for the treatment of various neurologic disorders, the most important of which being their ability to migrate to and differentiate predictably at sites of pathology in the brain. The disease-directed migration and well-characterized different...
journal_title:Neuroscience
pub_type: 杂志文章,评审
doi:10.1016/j.neuroscience.2011.08.063
更新日期:2011-12-01 00:00:00
abstract::Single steps in different directions are often used for postural corrections. However, our knowledge about the neural mechanisms underlying their generation is scarce. This study was aimed to characterize the corrective steps generated in response to disturbances of the basic body configuration caused by forward, back...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2017.02.007
更新日期:2017-04-07 00:00:00
abstract::Brain injury-derived neurotrophic peptide is a 13-amino acid peptide derived from a 15,000 mol. wt neurotrophic factor released from sites of mechanical injury in neonatal rat brain. This peptide promotes survival of septal cholinergic neurons and mesencephalic dopaminergic neurons, and protects hippocampal neurons fr...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(00)00136-6
更新日期:2000-01-01 00:00:00
abstract::Ascorbate is an antioxidant vitamin that is found in high concentrations in the brain which seems to have neuroprotective properties in some experimental models of excitotoxic neurological disorders, including convulsive behavior and reactive species-related damage. In this study we tested whether ascorbate (30, 100 o...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2004.07.012
更新日期:2004-01-01 00:00:00