The mossy fiber projection of the nucleus reticularis tegmenti pontis to the flocculus and adjacent ventral paraflocculus in the cat.

abstract：:Aging occurs due to a combination of several factors, such as telomere attrition, cellular senescence, and stem cell exhaustion. The telomere attrition-dependent cellular senescence is regulated by increased levels of SMAD specific E3 ubiquitin protein ligase 2 (smurf2). With age smurf2 expression increases and Smurf2...

journal_title：Neuroscience

authors： Sasik MUT,Eravsar ETK,Kinali M,Ergul AA,Adams MM

更新日期：2020-06-01 00:00:00

abstract：:Endopeptidase-24.11, which is identical with the common acute lymphoblastic leukemia antigen (CALLA), is a cell surface zinc metalloprotease that has the ability to hydrolyse a variety of physiologically active peptides. Interest in this enzyme is based on the view that it may play a role in the regulation of peptide ...

journal_title：Neuroscience

authors： Kioussi C,Crine P,Matsas R

更新日期：1992-09-01 00:00:00

abstract：:In order to observe the fine details of intracellularly stained neurons in brain slices the slices must be cleared of opaque matter. This clearing process involves dehydration of the slice, which typically results in significant shrinkage of the cleared tissue. However, how this shrinkage affects neuronal morphology h...

journal_title：Neuroscience

authors： Grace AA,Llinás R

更新日期：1985-10-01 00:00:00

abstract：:Metabotropic glutamate receptors are a major class of excitatory amino acid receptors. Eight metabotropic glutamate receptor subtypes have been cloned, and are classified into three groups (I, II and III) based on amino acid sequence identity, effector systems and pharmacological profile. Previous results have shown t...

journal_title：Neuroscience

authors： Kearney JA,Albin RL

更新日期：2000-01-01 00:00:00

abstract：:Walking onto a stationary sled previously experienced as moving induces locomotor aftereffects (LAE, or "broken escalator phenomenon"). This particular form of aftereffect can develop after a single adaptation trial and occurs despite subjects being fully aware that the sled will not move. Here, we investigate whether...

journal_title：Neuroscience

authors： Green DA,Bunday KL,Bowen J,Carter T,Bronstein AM

更新日期：2010-09-29 00:00:00

abstract：:Astrocyte hypertrophy and swelling occur in a variety of pathophysiological conditions, including diseases associated with hyperammonemia. Ammonia is rapidly incorporated into glutamine by glutamine synthetase localized in astrocytes. We tested the hypotheses that (1) 6 h of hyperammonemia (500-600 microM) is adequate...

journal_title：Neuroscience

authors： Willard-Mack CL,Koehler RC,Hirata T,Cork LC,Takahashi H,Traystman RJ,Brusilow SW

更新日期：1996-03-01 00:00:00

abstract：:Early experience and social context interact to alter the phenotype of complex social behaviors. These early experiences can also result in alterations to cortical organization and connections. Given the ability of the neuropeptide oxytocin (OT) to modulate social and reproductive behavior, OT is likely involved in th...

journal_title：Neuroscience

authors： Duchemin A,Seelke AM,Simmons TC,Freeman SM,Bales KL

更新日期：2017-04-21 00:00:00

abstract：:The experiments described herein present a method for tracking diffusion of the glucocorticoid receptor agonist RU28362 in brain following i.c.v. drug administration. A useful property of glucocorticoid receptor is that it is primarily cytoplasmic when unbound and rapidly translocates to the nucleus when bound by liga...

journal_title：Neuroscience

authors： Francis AB,Pace TW,Ginsberg AB,Rubin BA,Spencer RL

更新日期：2006-09-01 00:00:00

abstract：:Extracellular recordings were made from serotonergic neurons of the rat dorsal raphe nucleus in a slice preparation. In the presence of phenylephrine (3 microM) to restore the pacemaker activity of otherwise silent serotonergic neurons, superfusion with the 5-hydroxytryptamine1A agonist ipsapirone depressed the firing...

journal_title：Neuroscience

authors： Haj-Dahmane S,Hamon M,Lanfumey L

更新日期：1991-01-01 00:00:00

abstract：:Rat brain synaptosomes were isolated to study the effects of protein kinase inhibitors (sphingosine, 1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride, N-(6-aminohexyl)-5-chloro-1-naphtalenesulfonamide, staurosporine) on Ca2+-dependent and Ca2+-independent [14C]GABA release. The Ca2+-dependent [14C]GABA re...

journal_title：Neuroscience

authors： Storchak LG,Pozdnyakova NG,Himmelreich NH

更新日期：1998-08-01 00:00:00

abstract：:In this study co-localization of galanin- with calcitonin gene-related peptide (CGRP)-like immunoreactivity was examined in dorsal root ganglion neurons 14 days after sciatic nerve cut using a laser scanning confocal microscope. CGRP- and galanin-like immunoreactivities were also analysed in the dorsal horn of the spi...

journal_title：Neuroscience

authors： Zhang X,Bean AJ,Wiesenfeld-Hallin Z,Xu XJ,Hökfelt T

更新日期：1995-02-01 00:00:00

abstract：:The nicotinic receptor proteins and gene transcripts for the different nicotinic receptor subunits exist in human prenatal brain already at 4-5 weeks of gestation. The early presence of nicotinic receptors suggests an important role for these receptors in modulating dendritic outgrowth, establishment of neuronal conne...

journal_title：Neuroscience

authors： Hellström-Lindahl E,Seiger A,Kjaeldgaard A,Nordberg A

更新日期：2001-01-01 00:00:00

abstract：:In the adult CNS, GABA is the predominant inhibitory neurotransmitter, mediating the hyperpolarization of membrane potential and regulating the glutamatergic activity. In the immature CNS, on the other hand, GABA mediates depolarization and is involved in controlling morphogenesis. This developmental shift in GABA act...

journal_title：Neuroscience

authors： Takayama C,Inoue Y

更新日期：2006-12-01 00:00:00

abstract：:The superior temporal gyrus (STG) is involved in speech recognition against informational masking under cocktail-party-listening conditions. Compared to healthy listeners, people with schizophrenia perform worse in speech recognition under informational speech-on-speech masking conditions. It is not clear whether the ...

journal_title：Neuroscience

authors： Li J,Wu C,Zheng Y,Li R,Li X,She S,Wu H,Peng H,Ning Y,Li L

更新日期：2017-09-17 00:00:00

abstract：:Temporal lobe epilepsy (TLE) is the most common form of focal epilepsies in adults. It is often initiated by an insult or brain injury which triggers a series of alterations which ultimately lead to seizures (epilepsy). In 50-70% of people with TLE the condition cannot be adequately treated by the present antiepilepti...

journal_title：Neuroscience

authors： van Vliet EA,Aronica E,Gorter JA

更新日期：2014-09-26 00:00:00

abstract：:Allowing a resident hamster a single "priming" attack on a conspecific induces a transient aggressive arousal as indicated by a reduction in the latency and increase in the probability of attack on a second intruder presented within the next 30 min. We present two lines of evidence identifying the corticomedial amygda...

journal_title：Neuroscience

authors： Potegal M,Ferris CF,Hebert M,Meyerhoff J,Skaredoff L

更新日期：1996-12-01 00:00:00

abstract：:Recent studies have revealed that the ventral premotor cortex (PMv) of nonhuman primates plays a pivotal role in various behaviors that require the transformation of sensory cues to appropriate actions. Examples include decision-making based on various sensory cues, preparation for upcoming motor behavior, adaptive se...

journal_title：Neuroscience

authors： Kurata K

更新日期：2018-07-01 00:00:00

abstract：:In partially denervated skeletal muscle, spared motor fibres sprout, enlarging motor unit size. Neuritogenesis and sprouting are known to depend on the synaptic input to the neurons. This suggests that spared motoneuron reaction to partial muscle denervation might be controlled by primary sensory neurons which directl...

journal_title：Neuroscience

authors： Cuppini R,Ambrogini P,Sartini S

更新日期：1998-05-01 00:00:00

abstract：:This study examined the age-related subsequent memory effect (SME) in perceptual and semantic encoding using event-related potentials (ERPs). Seventeen younger adults and 17 older adults studied a series of Chinese characters either perceptually (by inspecting orthographic components) or semantically (by determining w...

journal_title：Neuroscience

authors： Kuo MC,Liu KP,Ting KH,Chan CC

更新日期：2014-03-07 00:00:00

abstract：:Field and intracellular potentials were recorded from CA1 pyramidal stratum in submerged slices (at 33 degrees). During "normal" oxygenation (95% O2 + 5% CO2), tonic depression of population spikes and field excitatory postsynaptic potentials by endogenous adenosine was demonstrated by (i) the marked enhancement by th...

journal_title：Neuroscience

authors： Zhu PJ,Krnjević K

更新日期：1994-11-01 00:00:00

abstract：:Using a semihorizontal section plane tangential to the ventral surface of the cerebral peduncle, the authors re-examined cyto-, myelo- and dendroarchitecture, acetylcholinesterase activity, afferent fibers, and efferent projection neurons of the substantia nigra pars reticulata. In the semihorizontal section plane, th...

journal_title：Neuroscience

authors： Tokuno H,Nakamura Y,Kudo M,Kitao Y

更新日期：1990-01-01 00:00:00

abstract：:The mechanisms involved in morphine tolerance are poorly understood. It was reported by our group that calcitonin gene-related peptide (CGRP)-like immunoreactivity (IR) was increased in the spinal dorsal horn during morphine tolerance [Ménard et al. (1996) J. Neurosci. 16, 2342-2351]. More recently, we observed that i...

journal_title：Neuroscience

authors： Belanger S,Ma W,Chabot JG,Quirion R

更新日期：2002-01-01 00:00:00

abstract：:Chronic stress, the administration of glucocorticoids and the prolonged activation of glucocorticoid receptors (GRs) are reported to induce affective changes in humans and rodents that resemble a depressive state. However, data concerning the behavioral and molecular effects of the selective activation of specific GRs...

journal_title：Neuroscience

authors： Skupio U,Tertil M,Sikora M,Golda S,Wawrzczak-Bargiela A,Przewlocki R

更新日期：2015-02-12 00:00:00

abstract：:Neurons in rat medulla oblongata with Fos immunoreactivity as a marker of synaptic excitation evoked by pentylenetetrazole-induced seizures were compared with cell populations activated by the stimulation of chemoreceptor and baroreceptor afferent pathways. Chemoreceptors were stimulated by placing rats in a hypoxic g...

journal_title：Neuroscience

authors： Kanter RK,Strauss JA,Sauro MD

更新日期：1996-08-01 00:00:00

abstract：:The nucleus retroambiguus in the cat has been shown to receive strong projections from the periaqueductal gray and to send fibres to distinct motoneuronal cell groups in brainstem and spinal cord. The nucleus retroambiguus plays a role in the production of vocalization and possibly copulatory (lordosis and mounting) b...

journal_title：Neuroscience

authors： Holstege G,Kerstens L,Moes MC,Vanderhorst VG

更新日期：1997-09-01 00:00:00

abstract：:Secretion of neurotrophins is critical for the delivery of neurotrophic support. Brain-derived neurotrophic factor is targeted to a regulated secretory pathway in neurons as well as the neurosecretory AtT-20 cells. Here, we show that pertussis toxin, which inactivates Gi and Go G proteins, inhibits up to 50% of the re...

journal_title：Neuroscience

authors： Gunther EC,von Bartheld CS,Goodman LJ,Johnson JE,Bothwell M

更新日期：2000-01-01 00:00:00

abstract：:Rapid eye movement sleep decreases between 10 and 30 days postnatally in the rat. The pedunculopontine nucleus is known to modulate waking and rapid eye movement sleep, and pedunculopontine nucleus neurons are thought to be hyperpolarized by noradrenergic input from the locus coeruleus. The goal of the study was to in...

journal_title：Neuroscience

authors： Bay KD,Mamiya K,Good CH,Skinner RD,Garcia-Rill E

更新日期：2006-08-25 00:00:00

abstract：:The globus pallidus, one of the basal ganglia nuclei, plays a major role in both basal ganglia physiology and pathophysiology. The globus pallidus is innervated mainly by striatal spiny neurons and globus pallidus collaterals. These GABAergic synapses constitute 90% of the input to globus pallidus cells. Despite the d...

journal_title：Neuroscience

authors： Rav-Acha M,Sagiv N,Segev I,Bergman H,Yarom Y

更新日期：2005-01-01 00:00:00

abstract：:Histochemistry for cytochrome oxidase reveals a vibrissa-related pattern in trigeminal nucleus principalis, subnucleus interpolaris, and the magnocellular portion of subnucleus caudalis. This pattern is apparent in late fetal animals and is disrupted by transection of the infraorbital nerve on the day of birth. We rec...

journal_title：Neuroscience

authors： Chiaia NL,Bennett-Clarke CA,Rhoades RW

更新日期：1992-07-01 00:00:00

abstract：:Repeated non-reinforced exposures of a neutral stimulus retard the development of a conditioned response to that stimulus when it is subsequently paired with a significant event. This stimulus pre-exposure effect is known as latent inhibition (LI). Early lesion studies have initially suggested an important role for th...

journal_title：Neuroscience

authors： Pouzet B,Zhang WN,Weiner I,Feldon J,Yee BK

更新日期：2004-01-01 00:00:00