The efferent vestibular system in the cat: a horseradish peroxidase and fluorescent retrograde tracers study.

abstract：:4-Aminopyridine (4-AP) is suggested to improve symptomatology of spinal injury patients because it may facilitate neuromuscular transmission, spinal impulse flow and the operation of the locomotor central pattern generator (CPG). Since 4-AP can also induce repetitive discharges from dorsal root afferents, this phenome...

journal_title：Neuroscience

authors： Taccola G,Nistri A

更新日期：2005-01-01 00:00:00

abstract：:NESP55 (neuroendocrine secretory protein of M(r) 55000) is a novel member of the chromogranin family. In the present study, we have investigated the distribution, axonal transport and proteolytic processing of NESP55 in the peripheral nervous system. The amount of NESP55 immunoreactivity in adrenal gland was more than...

journal_title：Neuroscience

authors： Li JY,Lovisetti-Scamihorn P,Fischer-Colbrie R,Winkler H,Dahlström A,Department of Anatomy and Cell Biology, University of Göteborg, Sweden. jiayi.li@anatcell.gu.se.

更新日期：2002-01-01 00:00:00

abstract：:The topographical organization of the subnuclear projections towards the thalamus was studied with autographic methods in adult Wistar rats. The four cerebellar deep nuclei give rise to projections to the ventral region of the rostral thalamus. Most of the fibers end contralaterally, according to a topographical patte...

journal_title：Neuroscience

authors： Angaut P,Cicirata F,Serapide F

更新日期：1985-06-01 00:00:00

abstract：:There is increasing evidence that a subset of midbrain dopamine (DA) neurons uses glutamate as a co-transmitter and expresses vesicular glutamate transporter (VGLUT) 2, one of the three vesicular glutamate transporters. In the present study, double in situ hybridization was used to examine tyrosine hydroxylase (TH) an...

journal_title：Neuroscience

authors： Dal Bo G,Bérubé-Carrière N,Mendez JA,Leo D,Riad M,Descarries L,Lévesque D,Trudeau LE

更新日期：2008-09-22 00:00:00

abstract：:Transgenic mice with overexpression of the caspase-inhibitor, X-chromosome-linked inhibitor of apoptosis protein (XIAP) in Purkinje cell (PC) and in retinal bipolar cells (RBCs) were produced to study the regulation of cell death. Unexpectedly, an increased neurodegeneration was observed in the PCs in these L7-XIAP mi...

journal_title：Neuroscience

authors： Korhonen L,Hansson I,Maugras C,Wehrle R,Kairisalo M,Borgkvist A,Jokitalo E,Sotelo C,Fisone G,Dusart I,Lindholm D

更新日期：2008-10-15 00:00:00

abstract：:The effects of X-irradiation on proliferating cells in the dentate subgranular zone were assessed in young adult Fisher 344 rats exposed to a range of X-ray doses and followed for up to 120 days. Apoptosis was quantified using morphology and end-labeling immunohistochemistry, and cell proliferation was detected using ...

journal_title：Neuroscience

authors： Tada E,Parent JM,Lowenstein DH,Fike JR

更新日期：2000-01-01 00:00:00

abstract：:Normal adult cerebellar Purkinje cells in the rat rarely express low-affinity nerve growth factor receptor immunoreactivity. However, intense anti-low-affinity nerve growth factor receptor immunostaining was observed as early as one day after a lesion of the cerebellar cortex. Low-affinity nerve growth factor receptor...

journal_title：Neuroscience

authors： Martínez-Murillo R,Caro L,Nieto-Sampedro M

更新日期：1993-02-01 00:00:00

abstract：:The enzyme choline-O-acetyltransferase catalyses the biosynthesis of acetylcholine from acetyl coenzyme A and choline and is considered as one of the best markers for cholinergic nerve endings. The distribution of this enzymatic activity was analysed during the purification of plasma membranes of purely cholinergic ne...

journal_title：Neuroscience

authors： Eder-Colli L,Amato S

更新日期：1985-06-01 00:00:00

abstract：:The aim of this study was to examine the development of the basalocortical pathway by using choline acetyltransferase and nerve growth factor receptor immunocytochemistry, acetylcholinesterase histochemistry and retrograde axonal transport. The observations were made in the ferret because in this species brain develop...

journal_title：Neuroscience

authors： Henderson Z

更新日期：1991-01-01 00:00:00

abstract：:Endomorphin 2 (EM2) plays essential roles in regulating nociceptive transmission within the spinal dorsal horn, where EM2-immunopositive (EM2-IP) fibers and terminals are densely encountered. However, the origins of these EM2-IP structures are still obscure. Unilateral primary sensory afferents disruption (lumbar 3-6 ...

journal_title：Neuroscience

authors： Hui R,Wang W,Chen T,Lü BC,Li H,Zhang T,Wu SX,Li YQ

更新日期：2010-08-11 00:00:00

abstract：:Neural activity during early development is known to alter innervation pathways in the central and peripheral nervous systems. We sought to examine how reduced sound-induced sensory activity in the cochlea affected the consolidation of glutamatergic synapses between inner hair cells (IHC) and the primary auditory neur...

journal_title：Neuroscience

authors： Barclay M,Constable R,James NR,Thorne PR,Montgomery JM

更新日期：2016-06-14 00:00:00

abstract：:In anaesthetized adult rats, facial nerve injury causes a disinhibition of the interhemispheric connections between homotopic representation fields in the primary motor cortex with a latency of 4 min (Toldi et al., 1996, Neurosci Lett. 203, 179-182). One possible explanation for the induction of such rapid changes is ...

journal_title：Neuroscience

authors： Farkas T,Kis Z,Toldi J,Wolff JR

更新日期：1999-05-01 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disorder primarily affecting the dopaminergic neurons in the nigrastriatal pathway resulting in debilitating motor impairment in both familial and sporadic cases. Histone deacetylase (HDAC) inhibitors have been recently implicated as a therapeutic candidate because of th...

journal_title：Neuroscience

authors： St Laurent R,O'Brien LM,Ahmad ST

更新日期：2013-08-29 00:00:00

abstract：:Agrin is a multi-domain protein best known for its essential function during formation of the neuromuscular junction. Alternative mRNA splicing at sites named y and z in the C-terminal part of agrin regulates its interaction with a receptor complex consisting of the agrin-binding low-density lipoprotein receptor-relat...

journal_title：Neuroscience

authors： Handara G,Kröger S

更新日期：2019-11-01 00:00:00

abstract：:Activation of angiotensinergic pathways by central aldosterone (Aldo)-mineralocorticoid receptor (MR) pathway plays a critical role in angiotensin II (Ang II)-induced hypertension. The subfornical organ (SFO) contains both MR and angiotensin II type 1 receptors (AT1R) and can relay the signals of circulating Ang II to...

journal_title：Neuroscience

authors： Wang HW,Huang BS,White RA,Chen A,Ahmad M,Leenen FH

更新日期：2016-08-04 00:00:00

abstract：:Traumatic brain injury (TBI) is a major cause of morbidity and mortality world-wide and can result in persistent cognitive, sensory and behavioral dysfunction. Understanding the time course of TBI-induced pathology is essential to effective treatment outcomes. We induced TBI in rats using an impact acceleration method...

journal_title：Neuroscience

authors： Allitt BJ,Iva P,Yan EB,Rajan R

更新日期：2016-10-15 00:00:00

abstract：:Nucleus raphe magnus contains a large population of raphe-spinal serotonergic neurons that are thought to be involved in descending control of pain transmission and the modulation of opioid analgesia. Intracellular recordings were made from nucleus raphe magnus neurons in the slice preparation. Cells were divided into...

journal_title：Neuroscience

authors： Pan ZZ,Wessendorf MW,Williams JT

更新日期：1993-05-01 00:00:00

abstract：:Alterations of nitric oxide (NO) metabolism in the brain have been associated with modifications of stress-related behavior in animal models. It has been generally assumed that these behavioral changes are due to the neuronal nitrosative activity. On the other hand, glial NO production has been demonstrated mainly as ...

journal_title：Neuroscience

authors： Abu-Ghanem Y,Cohen H,Buskila Y,Grauer E,Amitai Y

更新日期：2008-10-02 00:00:00

abstract：:Oxytocin and vasopressin binding sites were localized and characterized by quantitative autoradiography on consecutive sections of Long-Evans rat forebrains and pituitary glands, incubated in the presence of 5 nM [3H]oxytocin or 5 nM [3H]vasopressin. In the forebrain, two types of neurohypophysial hormone binding site...

journal_title：Neuroscience

authors： Freund-Mercier MJ,Stoeckel ME,Dietl MM,Palacios JM,Richard P

更新日期：1988-07-01 00:00:00

abstract：:The antidromic activation of facial nucleus montoneurones has been studied in acute experiments on cats by means of extra- and intracellular recording techniques. Time and amplitude characteristics of separate components of the antidromic action potential and the after--potentials accompanying it have been analyzed. A...

journal_title：Neuroscience

authors： Fanardjian VV,Manvelyan LR,Kasabyan SA

更新日期：1983-08-01 00:00:00

abstract：:Apoptosis, or programmed cell death, resulting from cerebral ischemia may be related to decreased levels of anti-apoptotic factors, such as serine/threonine kinase (Akt), phosphorylated Akt (pAkt), pBAD, and Bcl-2, and increased levels of pro-apoptotic factors, such as BAD, caspase 9, and caspase 3 activities. In this...

journal_title：Neuroscience

authors： Yip KK,Lo SC,Leung MC,So KF,Tang CY,Poon DM

更新日期：2011-09-08 00:00:00

abstract：:Extracellular single-unit recording methods were used to study the activity of neurons within a restricted portion of the dorsolateral mesopontine reticular formation, an area which includes the parabrachial, pedunculopontine tegmental and cuneiform nuclei. Recordings were obtained during presentations of unfamiliar a...

journal_title：Neuroscience

authors： Pascoe JP,Kapp BS

更新日期：1993-06-01 00:00:00

abstract：:Investigation of the integrity of the ryanodine receptor in Alzheimer's disease is important because it plays a critical role in the regulation of calcium release from the endoplasmic reticulum in brain, impairment of which is believed to contribute to the pathogenesis of Alzheimer's disease. The present study compare...

journal_title：Neuroscience

authors： Kelliher M,Fastbom J,Cowburn RF,Bonkale W,Ohm TG,Ravid R,Sorrentino V,O'Neill C

更新日期：1999-01-01 00:00:00

abstract：:Mental function has as its cerebral basis a specific dynamic structure. In particular, cortical and limbic areas involved in "higher brain functions" such as learning, memory, perception, self-awareness and consciousness continuously need to be self-adjusted even after development is completed. By this lifelong self-o...

journal_title：Neuroscience

authors： Arendt T

更新日期：2001-01-01 00:00:00

abstract：:Slices of striatal tissue from newborn to eight-day-old rats were cultured for six to 47 days. Cholinergic neurons and fibres were then visualized by histochemical staining for acetylcholinesterase or immunocytochemical staining for choline acetyltransferase. GABA-containing neurons and fibres were visualized by immun...

journal_title：Neuroscience

authors： Ostergaard K

更新日期：1993-04-01 00:00:00

abstract：:Riluzole, an anti-amyotrophic lateral sclerosis drug, known to decrease presynaptic glutamate release, is viewed as a candidate supplementary medication for epilepsy. In the present study, we compared the effects of riluzole and valproate (VPA) in the pilocarpine-induced limbic seizure model and in the gamma-hydroxybu...

journal_title：Neuroscience

authors： Kim JE,Kim DS,Kwak SE,Choi HC,Song HK,Choi SY,Kwon OS,Kim YI,Kang TC

更新日期：2007-06-15 00:00:00

abstract：:The distribution of D1 dopamine receptors was studied autoradiographically in the basal ganglia of the cat, monkey and human. These receptor binding sites were labeled directly with the D1-selective antagonist [3H]SCH 23390, and ligand-binding assays were performed concurrently. Serial- or same-action analysis permitt...

journal_title：Neuroscience

authors： Besson MJ,Graybiel AM,Nastuk MA

更新日期：1988-07-01 00:00:00

abstract：:The neuropeptides somatostatin, neurotensin and substance P were investigated in rats during and after limbic seizures induced by systemic injection of kainic acid (10 mg/kg, i.p.). Three hours after injection of the toxin, pronounced decreases (40-50%) in somatostatin-like immunoreactivity in frontal cortex, striatum...

journal_title：Neuroscience

authors： Sperk G,Wieser R,Widmann R,Singer EA

更新日期：1986-04-01 00:00:00

abstract：:The present research explored the cortical correlates of emotional memories in response to words and pictures. Subjects' performance (Accuracy Index, AI; response times, RTs; RTs/AI) was considered when a repetitive Transcranial Magnetic Stimulation (rTMS) was applied on the left dorsolateral prefrontal cortex (LDLPFC...

journal_title：Neuroscience

authors： Balconi M,Cobelli C

更新日期：2015-02-26 00:00:00

abstract：:Reflex response of fusimotoneurons to sinusoidal muscle stretching were investigated in decerebrated cats. Nerve impulses of single fusimotoneurons were recorded from thin filaments dissected from otherwise intact nerves to triceps surae muscles. Amplitude of the sinusoidal stretching of these muscles was 3 mm peak-to...

journal_title：Neuroscience

authors： Anastasijević R,Jovanović K,Vuco J

更新日期：1990-01-01 00:00:00