解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Marine picocyanobacteria belonging to genera Synechococcus and Prochlorococcus are genetically diverged and distributed into distinct biogeographical patterns, and both are infected by genetically closely related cyanopodoviruses. Previous studies have not fully explored whether the two virus-host systems share simila...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1150
更新日期:2020-12-30 00:00:00
abstract:AIMS:To assess a cost-effective in-house selective plate formula for actively screening carbapenem-resistant Enterobacteriaceae (CRE). METHODOLOGY AND RESULTS:The in-house formula included CHROMagarTM Orientation, meropenem, and ingredients present in the Mac-Conkey formula, such as bile salts and crystal violet (pH 6...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1130
更新日期:2020-12-01 00:00:00
abstract::The black pigmentation-related genes in Porphyromonas gingivalis are primarily involved in regulating gingipain functions. In this study, we identified a pigmentation-related gene, designated as pgn_0361. To characterize the role of pgn_0361 in regulating P. gingivalis-mediated epithelial cell detachment and inhibitio...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1128
更新日期:2020-12-01 00:00:00
abstract::Bacterial nitric oxide (NO) synthases (bNOS) play diverse and important roles in microbial physiology, stress resistance, and virulence. Although bacterial and mammalian NOS enzymes have been well-characterized, comparatively little is known about the prevalence and function of NOS enzymes in Archaea. Analysis of arch...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1124
更新日期:2020-11-01 00:00:00
abstract::To investigate the possible effects of sulfamonomethoxine (SMM) on Nile tilapia (Oreochromis niloticus), we quantitatively evaluated the microbial shifts in the intestines of Nile tilapia in response to different doses of SMM (200 and 300 mg/kg) using 16S rRNA gene sequencing. At the phylum level, the control group (0...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1116
更新日期:2020-11-01 00:00:00
abstract::Directed enzyme prodrug therapy (DEPT) is a cancer chemotherapy strategy in which bacterial enzymes are delivered to a cancer site before prodrug administration, resulting in prodrug activation at the cancer site and more localized treatment. A major limitation to DEPT is the poor effectiveness of the most studied enz...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1110
更新日期:2020-10-01 00:00:00
abstract::Phellinus noxius is a pathogenic fungus that causes brown root rot disease, resulting in a widespread tree and crop mortality in the tropics and subtropics. Early stages of this disease are largely asymptomatic, hindering early diagnosis and effective treatment. We hypothesized that P. noxius infection would alter the...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1115
更新日期:2020-10-01 00:00:00
abstract::Brazil is the biggest producer of sweet oranges and the main exporter of concentrated orange juice in the world. Among the diseases that affect citriculture, Asiatic citrus canker, caused by the bacterial pathogen Xanthomonas citri, represents one of the most significant threats. The current Brazilian legislation regu...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1104
更新日期:2020-09-01 00:00:00
abstract::Few studies have evaluated the trophic level in tropical caves, and none related the microbial biomass dynamics in the immobilization of carbon and nitrogen. Here, four tropical caves of Terra Ronca State Park, Brazil, were studied: Angélica, São Bernardo, Terra Ronca I, and Terra Ronca II caves. Physical, chemical, a...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1044
更新日期:2020-07-01 00:00:00
abstract::Sustained monoculture often leads to the inhibition of plant growth, the decrease of the soil microbial diversity, and changes in soil microbial community composition, particularly to the accumulation of soil-borne pathogens. In this study, we conducted field experiments to investigate the practical effects of tilling...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1045
更新日期:2020-07-01 00:00:00
abstract::[NiFe]-hydrogenases catalyze the reversible conversion of molecular hydrogen into protons end electrons. This reaction takes place at a NiFe(CN)2 (CO) cofactor located in the large subunit of the bipartite hydrogenase module. The corresponding apo-protein carries usually a C-terminal extension that is cleaved off by a...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1029
更新日期:2020-06-01 00:00:00
abstract::Gene expression in Haloarcula hispanica cells infected with the gammapleolipovirus His2 was studied using a custom DNA microarray. Total RNA from cells sampled at 0, 1, 2, 3, and 4.5 hr postinfection was reverse-transcribed into labeled cDNA and hybridized to microarrays, revealing temporal and differential expression...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1016
更新日期:2020-05-01 00:00:00
abstract::Microbially mediated decomposition of particulate organic carbon (POC) is a central component of the oceanic carbon cycle, controlling the flux of organic carbon from the surface ocean to the deep ocean. Yet, the specific microbial taxa responsible for POC decomposition and degradation in the deep ocean are still unkn...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1013
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:The microbiome is an integral component of many animal species, potentially affecting behavior, physiology, and other biological properties. Despite this importance, bacterial communities remain vastly understudied in many groups of invertebrates, including mites. Quill mites (Acariformes: Syringophilidae) a...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.964
更新日期:2020-05-01 00:00:00
abstract::Methicillin-resistant S. aureus has been reported as the main pathogen involved in chronic infections, osteomyelitis, and prosthetic joint infections. The host/pathogen interaction is dynamic and requires several changes to promote bacterial survival. Here, we focused on the internalization and persistence behavior of...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1017
更新日期:2020-05-01 00:00:00
abstract::Sourdough fermentation is a traditional process that is used to improve bread quality. A spontaneous sourdough ecosystem consists of a mixture of flour and water that is fermented by endogenous lactic acid bacteria (LAB) and yeasts. The aim of this study was to identify bacterial diversity during backslopping of spont...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.1009
更新日期:2020-04-01 00:00:00
abstract::Most DNA assembly methods require bacterial amplification steps, which restrict its application to genes that can be cloned in the bacterial host without significant toxic effects. However, genes that cannot be cloned in bacteria do not necessarily exert toxic effects on the final host. In order to tackle this issue, ...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.978
更新日期:2020-03-01 00:00:00
abstract::The intraspecies genomic diversity of the single-strand RNA (+) virus species hepatitis A virus (Hepatovirus), hepatitis C virus (Hepacivirus), and hepatitis E virus (Orthohepevirus) was compared. These viral species all can cause liver inflammation (hepatitis), but share no gene similarity. The codon usage of human h...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.973
更新日期:2020-02-01 00:00:00
abstract::Interactions between corals and their associated microbial communities (Symbiodiniaceae and prokaryotes) are key to understanding corals' potential for and rate of acclimatory and adaptive responses. However, the establishment of microalgal and bacterial communities is poorly understood during coral ontogeny in the wi...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.959
更新日期:2020-02-01 00:00:00
abstract::Probiotic bacteria are frequently used to treat intestinal diseases or to improve health; however, little is known about the evolutionary changes of these bacteria during probiotic manufacture and the bacterial ability to colonize the intestine. It has been observed that when bacteria adapt to a new environment, they ...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.972
更新日期:2020-02-01 00:00:00
abstract::Protein lysine acetylation, a dynamic and reversible posttranslational modification, plays a crucial role in several cellular processes, including cell cycle regulation, metabolism, enzymatic activities, and protein interactions. Brenneria nigrifluens is a pathogen of walnut trees with shallow bark canker and can caus...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.952
更新日期:2020-01-01 00:00:00
abstract::Extracts from white birch have been reported to possess antimicrobial properties, but no study has linked the chemical composition of bark extract with antimicrobial activity. This study aimed to identify white birch (Betula papyrifera Marshall) bark extracts with antimicrobial activity and elucidate its composition. ...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.944
更新日期:2020-01-01 00:00:00
abstract::The Siamese crocodile (Crocodylus siamensis) is a freshwater, endangered crocodile with high economic value in the farming industry. Gut microflora plays an essential role in host physiological activity, and it contributes significantly to both the health and diseased states of animals. However, thus far, no study has...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.929
更新日期:2019-12-01 00:00:00
abstract::A yeast expression plasmid was constructed containing a cardenolide biosynthetic module, referred to as CARD II, using the AssemblX toolkit, which enables the assembly of large DNA constructs. The genes cloned into the vector were (a) a Δ5 -3β-hydroxysteroid dehydrogenase gene from Digitalis lanata, (b) a steroid Δ5 -...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.925
更新日期:2019-12-01 00:00:00
abstract::Soil water content (SWC) is an important determinant for nutrient cycling and microorganism activity in the grassland ecosystem. Lakes have a positive effect on the water supply of the neighboring ecosystem. However, information evaluating whether newly built lakes improve the physiochemical properties and microorgani...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.912
更新日期:2019-12-01 00:00:00
abstract::Bacterial colonization of the urogenital tract is limited by innate defenses, including the production of antimicrobial peptides (AMPs). Uropathogenic Escherichia coli (UPEC) resist AMP-killing to cause a range of urinary tract infections (UTIs) including asymptomatic bacteriuria, cystitis, pyelonephritis, and sepsis....
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.915
更新日期:2019-11-01 00:00:00
abstract::The emerging pollutants antibiotic resistance genes (ARGs) are prevalent in aquatic environments such as estuary. Coastal mangrove ecosystems always serve as natural wetlands for receiving sewage which always carry ARGs. Currently, the research considering ARG distribution in mangrove ecosystems gains more interest. I...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.871
更新日期:2019-11-01 00:00:00
abstract::The small hive beetle (SHB) is an opportunistic parasite that feeds on bee larvae, honey, and pollen. While SHBs can also feed on fruit and other plant products, like its plant-feeding relatives, SHBs prefer to feed on hive resources and only reproduce inside bee colonies. As parasites, SHBs are inevitably exposed to ...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.899
更新日期:2019-10-01 00:00:00
abstract::The composition and function of the microbial community in the gastrointestinal tract (GIT) have increasingly captured the attention of nutritionists because these traits affect the nutrient utilization efficiency and health of host animals. Little information has been reported on these aspects of the goat GIT. This s...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.820
更新日期:2019-09-01 00:00:00
abstract::Microbial communities in sediments play an important role in alpine lake ecosystems. However, the microbial diversity and community composition of alpine lake sediments from the Hengduan Mountains remain largely unknown. Therefore, based on the Illumina MiSeq platform, high-throughput sequencing analysis of the 16S rR...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.832
更新日期:2019-09-01 00:00:00
abstract::In cyanobacteria, genes conferring mercury resistance are not organized as mer-operon, unlike in other bacterial phyla. Synechocystis contains only a putative MerR regulator, Slr0701, and a mercury reductase, MerA, located aside from each other in the genome. The slr0701-mutant showed reduction in photosynthetic activ...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.838
更新日期:2019-09-01 00:00:00
abstract::The nitrogenase complex in the heterocysts of the filamentous freshwater cyanobacterium Anabaenasp. PCC 7120 fixes atmospheric nitrogen to allow diazotrophic growth. The heterocyst cell envelope protects the nitrogenase from oxygen and consists of a polysaccharide and a glycolipid layer that are formed by a complex pr...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.811
更新日期:2019-08-01 00:00:00
abstract::The Hatton-Rockall Basin (North-East Atlantic) is an area with potential for deep-sea (2,900 m) hydrocarbon exploration. Following the Deepwater Horizon oil spill, many investigations into the responses of sediment microbial communities to oil pollution have been undertaken. However, hydrostatic pressure is a paramete...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.768
更新日期:2019-06-01 00:00:00
abstract::The OMPs A (OmpA)-of Edwardsiella anguillarum and OmpU of V. vulnificus have been proven to be good antigens. In this study, after construction of a vector, a new recombinant Omp (rOMP) containing both OmpA and OmpU was expressed and purified. Then, the Japanese eels (Anguilla japonica) were intraperitoneally (i.p.) i...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.766
更新日期:2019-06-01 00:00:00
abstract::Urinary tract infections (UTIs) are among the most common bacterial infections in humans. Although a number of bacteria can cause UTIs, most cases are due to infection by uropathogenic Escherichia coli (UPEC). UPEC are a genetically heterogeneous group that exhibit several virulence factors associated with colonizatio...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.756
更新日期:2019-06-01 00:00:00
abstract::It is common knowledge that fecal microbiota is a primary source of Escherichia coli causing urinary tract infections (UTIs) via the fecal-perineal-urethral route. But, it is still unknown whether E. coli UTI is mainly caused by dominant fecal E. coli isolates (prevalence hypothesis) or the isolates that possess more ...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.759
更新日期:2019-06-01 00:00:00
abstract::As part of the culturomics project aiming at describing the human microbiota, we report in this study the description of the new bacterial genus Raoultibacter gen. nov. that includes two new species, that is, R. massiliensis sp. nov. and R. timonensis sp. nov. The R. massiliensis type strain Marseille-P2849T was isola...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.758
更新日期:2019-06-01 00:00:00
abstract::Microorganisms require a motility structure to move towards optimal growth conditions. The motility structure from archaea, the archaellum, is fundamentally different from its bacterial counterpart, the flagellum, and is assembled in a similar fashion as type IV pili. The archaellum filament consists of thousands of c...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.718
更新日期:2019-05-01 00:00:00
abstract::Acinetobacter baumannii is a nosocomial pathogen which can persist in the hospital environment not only due to the acquirement of multiple antibiotic resistances, but also because of its exceptional resistance against disinfectants and desiccation. A suitable desiccation assay was established in which A. baumannii ATC...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.740
更新日期:2019-05-01 00:00:00
abstract::The aim of this study was to determine the serogroups, antimicrobial resistance and genetic diversity of Escherichia coli isolates from samples of bivalve mollusks collected along Santa Catarina coast, Brazil, and from the Chesapeake Bay, Maryland, USA. One hundred forty-one E. coli isolates were characterized for ser...
journal_title:MicrobiologyOpen
pub_type: 杂志文章
doi:10.1002/mbo3.738
更新日期:2019-05-01 00:00:00