解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The content of ursolic acid and oleanolic acid was determined in different plant parts of two Glechoma species, G. hederacea and G. hirsuta. To achieve optimal extraction conditions of ursolic acid and oleanolic acid from plant material, several methods including maceration, heat reflux, Soxhlet, and ultrasonic extrac...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1345-9377
更新日期:2021-01-15 00:00:00
abstract::Lime flowers, traditionally used for medical purposes for the treatment of symptoms of the common cold and mental stress, consist of the dried inflorescences including the floral bracts of Tilia cordata, Tilia platyphyllos, Tilia × vulgaris, or mixtures thereof. During phytochemical investigations, 6 different alkaloi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1340-0099
更新日期:2021-01-12 00:00:00
abstract::Four isocedrenes (1: - 4: ), including one new compound (2: ), were isolated from an ethanolic extract of the aerial parts of Perezia multiflora by bioactivity-guided fractionation. For compounds 1: and 3: , a revised stereochemical assignment is proposed based on molecular modeling studies using DFT-NMR calculations...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1298-4706
更新日期:2020-11-23 00:00:00
abstract::Plant volatile organic compounds (volatiles) are secondary plant metabolites that play crucial roles in the reproduction, defence, and interactions with other vegetation. They have been shown to exhibit a broad range of biological properties and have been investigated for antimicrobial and anticancer activities. In ad...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1289-4505
更新日期:2020-11-11 00:00:00
abstract::Continued examination of the stem bark of Newbouldia laevis afforded three minor phenylethanoid glycosides, designated as newbouldiosides D - F. Their structures were elucidated by spectroscopic methods as β-(3,4-dihydroxyphenyl)ethyl 5-O-syringoyl-β-D-apiofuranosyloxy-(1 → 2)-O-[α-L-rhamnopyranosyl-(1 → 3)]-6-O-E-sin...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1270-7761
更新日期:2020-11-06 00:00:00
abstract::Juniperus (Cupressaceae, Pinales) plants are widely distributed in the Qinghai-Tibet Plateau of China. The leaves and twigs of at least 8 Juniperus species (J. pingii, J. pingii var. wilsonii, J. squamata, J. recurva var. coxii, J. saltuaria, J. indica, J. tibetica and J. convallium var. microsperma) have been used as...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1194-0471
更新日期:2020-11-01 00:00:00
abstract::Three new depsidones, parmosidones F - G (1 - 2), and 8'-O-methylsalazinic acid (3), and 3 new diphenylethers, parmetherines A - C (4 - 6), together with 2 known congeners were isolated from the whole thalli of Parmotrema dilatatum, a foliose chlorolichen. Their structures were unambiguously determined by extensive sp...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1203-0623
更新日期:2020-11-01 00:00:00
abstract::Three previously undescribed natural products, phomopsinin A - C (1: - 3: ), together with three known compounds, namely, cis-hydroxymellein (4: ), phomoxanthone A (5: ) and cytochalasin L-696,474 (6: ), were isolated from the solid culture of Phomopsis sp. CAM212, an endophytic fungus obtained from Garcinia xanthoch...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1212-2930
更新日期:2020-09-01 00:00:00
abstract::The endophytic microbiome in medicinal plants is rich and diverse, but few studies have followed the endophytic microbiome of medicinal plants in different tissues with their growth. In this study, we examined the endophytic bacterial and fungal community structures associated with both the stem and root compartments ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1046-1022
更新日期:2020-09-01 00:00:00
abstract::The dietary intake of flavonoids seems to be inversely related to cardiovascular mortality. The consumption of isoflavonoids is increasing in the general population, especially due to the use of food supplements and a variety of isoflavonoid-rich foods. However, detailed studies on the vascular influence of individual...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1158-9422
更新日期:2020-07-01 00:00:00
abstract::Malaria is a parasitic disease endemic to tropical and subtropical regions responsible for hundreds of millions of clinical cases and hundreds of thousands of deaths yearly. Its agent, the Plasmodium sp., has a highly variable antigenicity, which accounts for the emergence and spread of resistance to all available tre...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/a-1148-9000
更新日期:2020-06-01 00:00:00
abstract::Tuberculosis is the main cause of death from a single infectious agent. Globally, according to the World Health Organization, in 2018, there were an estimated 1.2 million tuberculosis deaths. Moreover, there is a continuous appearance of drug-resistant strains. Thus, development of new antituberculosis medicines shoul...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1157-1732
更新日期:2020-05-11 00:00:00
abstract::Annona purpurea has been traditionally used by indigenous and socioeconomically disadvantaged people to treat infectious and parasitic diseases, including amoebiasis. The goal of this study was to assess the effect of a crude methanolic extract, an alkaloid extract, and aporphine alkaloids from leaves of A. purpurea o...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1111-9566
更新日期:2020-04-01 00:00:00
abstract::Infections caused by HSV-2 are a public health concern worldwide, and there is still a great demand for the discovery of novel anti-herpes virus agents effective against strains resistant to current antiviral agents. In this context, medicinal plants represent an alternative source of active compounds for developing e...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1087-8303
更新日期:2020-03-01 00:00:00
abstract::A fixed combination of Berberis aristata and Silybum marianum (Berberol) has been used by patients with dyslipidaemia. The aim of the present meta-analysis was to systematically evaluate the efficacy and safety of a fixed combination of B. aristata and S. marianum (Berberol) on serum lipid levels compared to placebo i...
journal_title:Planta medica
pub_type: 杂志文章,meta分析
doi:10.1055/a-1063-1649
更新日期:2020-01-01 00:00:00
abstract::In previous studies, crude Houttuynia cordata polysaccharides showed beneficial effects on acute lung injury in vivo, a syndrome in which anti-complementary activities played an important role. Anti-complementary activity-guided fractionation of H. cordata polysaccharides led to the isolation of two highly branched ho...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0955-7841
更新日期:2019-09-01 00:00:00
abstract::Malaria treatment and control have become increasingly difficult because of the spread of drug-resistant strains of Plasmodium falciparum and Plasmodium vivax. Thus, there is a continuous need to develop new combination therapies such as artemisinin-based combination therapies (ACTs) to contrast the emergence of resis...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0952-3677
更新日期:2019-08-01 00:00:00
abstract::Ideally, metabolomics should deal with all the metabolites that are found within cells and biological systems. The most common technologies for metabolomics include mass spectrometry, and in most cases, hyphenated to chromatographic separations (liquid chromatography- or gas chromatography-mass spectrometry) and nucle...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0947-5797
更新日期:2019-08-01 00:00:00
abstract::Targeted isolation based on a combination of NMR and HPLC-PDA-MS of a dichloromethane extract of Thymus vulgaris Varico 3 aerial parts afforded one new p-cymene dimer, 6,3',4'-trihydroxy-5,5'-diisopropyl-2,2'-dimethylbiphenyl (1: ), together with two known p-cymene derivatives (2: and 3: ), as well as five known compo...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0927-7041
更新日期:2019-08-01 00:00:00
abstract::Halimium halimifolium (Hh) is a shrub used in Algerian folk medicine to treat gastrointestinal pain. An UHPLC-PDA-ESI/MSn method was developed to identify the metabolic profile of the traditionally used infusion (Hh-A) from the aerial parts. The structures of flavanols were confirmed by NMR analysis after the isolatio...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0953-6007
更新日期:2019-08-01 00:00:00
abstract::Stellera chamaejasme, also known as "Langdu", has been traditionally used for the management of skin-related diseases such as psoriasis and skin ulcers. The aim of this study was to determine whether S. chamaejasme and its major component, luteolin 7-O-glucoside, have a preventive effect on the development of atopic d...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0746-8698
更新日期:2019-05-01 00:00:00
abstract::Menopause is characterized by deep metabolic disturbances, including decreased insulin sensitivity, adiposity, and changes in lipid profiles. Estrogen replacement therapy can partially reverse these changes, and while it is safe in most healthy postmenopausal women, there are still existing concerns regarding an incre...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0835-6622
更新日期:2019-04-01 00:00:00
abstract::Casearin X (CAS X) is the major clerodane diterpene isolated from the leaves of Casearia sylvestris and has been extensively studied due to its powerful cytotoxic activity at low concentrations. Promising results for in vivo antitumor action have also been described when CAS X was administered intraperitoneally in mic...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0765-9523
更新日期:2019-03-01 00:00:00
abstract::Usnic acid, a lichen secondary metabolite produced by a whole number of lichens, has attracted the interest of researchers owing to its broad range of biological activity, including antiviral, antibiotic, anticancer properties, and it possessing a certain toxicity. The synthesis of new usnic acid derivatives and the i...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0681-7069
更新日期:2019-01-01 00:00:00
abstract::Mammea-type coumarins are a particular type of secondary metabolites biosynthesized by the tropical rainforest tree Calophyllum Brasiliense, which is distributed from South America to Mexico. Particularly, mammea A/BA and A/BB (alone or as a mixture) possess biological properties such as cytotoxic and antitumoral acti...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0660-0236
更新日期:2019-01-01 00:00:00
abstract::Six new neo-clerodane diterpenoids (1: -6: ), scutebatas X - Z, A1-C1, along with twelve known ones (7: -18: ) were obtained via the phytochemical investigation of the aerial parts of Scutellaria barbata. Their structures were established by detailed spectroscopic analysis. The absolute configurations of 1: and 2: , a...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0638-8255
更新日期:2018-11-01 00:00:00
abstract::Piper methysticum (Kava) is a plant whose roots are used in the preparation of traditional beverages with spiritual, medicinal, and social importance for the Pacific Islanders. Kava is also sold as a herbal supplement or recreational beverage consumed for its mild inebriating effect in Europe and North America. With a...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0637-2400
更新日期:2018-11-01 00:00:00
abstract::A phytochemical study of the roots of Pongamia pinnata afforded 29 flavanones and flavanols, including 7 previously undescribed compounds. The structures of the isolated compounds were determined by 1D and 2D NMR and mass spectroscopy data. The absolute configurations of the compounds were assigned via analysis of the...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0626-7356
更新日期:2018-11-01 00:00:00
abstract::The aerial parts of Guarea guidonia afforded three new tirucallane-type triterpenoids: 3,4-seco-tirucalla-4(28),8(9),24(25)-trien-7α,11α-dihydroxy-21,23-epoxy-3,11-olide, named guareolide (1: ), 3,4-seco-tirucalla-4(28),7(8),24(25)-trien-21-hydroxy-21,23-epoxy-3-oic acid, named guareoic acid A (2: ), and 3,4-seco-tiru...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0044-100524
更新日期:2018-07-01 00:00:00
abstract::Use of herbal dietary supplements by the public is common and has been happening for centuries. In the United States, the Food and Drug Administration has a limited scope of regulation over marketed herbal dietary supplements, which may contain toxic botanical compounds that pose a public health risk. While the Food a...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/a-0605-3786
更新日期:2018-07-01 00:00:00
abstract::Quality control of drugs consists of identifying the raw material to avoid unwanted admixtures or exchange of material as well as looking for abiotic and biotic contaminations. So far, identity and microbial contamination are analyzed by separate processes and separate methods. Species identification by their DNA ("DN...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-121470
更新日期:2018-04-01 00:00:00
abstract::Endothelial dysfunction is characterised by the low bioavailability of nitric oxide with a relevant negative impact on the nitric oxide/cGMP pathway. The loss of nitric oxide/cGMP signaling may be caused by an increased arginase activity. Plant-derived substances, especially polyphenols, are compounds that have the po...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-0044-100398
更新日期:2018-03-01 00:00:00
abstract::Cannabis (Cannabis sativa L.) is an annual herbaceous plant that belongs to the family Cannabaceae. Trans-Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) are the two major phytocannabinoids accounting for over 40% of the cannabis plant extracts, depending on the variety. At the University of Mississippi, differ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-124088
更新日期:2018-03-01 00:00:00
abstract::Recently, an increasing number of pharmacists had to supply medicinal products based on Cannabis sativa L. (Cannabaceae), prescribed by physicians to individual patients. Cannabis olive oil preparation is the first choice as a concentrated extract of cannabinoids, even though standardized operative conditions for obta...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-123074
更新日期:2018-03-01 00:00:00
abstract::The anti-inflammatory effects of boldine and reticuline isolated from Litsea cubeba were evaluated by using xylene-induced ear edema and carrageenan-induced paw edema in mice and rats. Our results demonstrated that intragastric administration with boldine and reticuline significantly mitigated ear weight in mice and d...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-113447
更新日期:2018-01-01 00:00:00
abstract::Ocimum tenuiflorum has been widely used in traditional medicine and has high medicinal value. High volume trade of this potential medicinal plant species led to unscrupulous adulteration of both crude drugs as well as formulations. Morphology-based authentication is difficult in cases of incomplete or damaged samples ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-116853
更新日期:2018-01-01 00:00:00
abstract::The genetic barcode ITS2 (ITS: internal transcribed spacer) and pollen morphology were used for the identification of the pharmacologically valuable wild Araliaceae species Panax ginseng, Oplopanax elatus, Aralia elata, Aralia continentalis, Eleutherococcus senticosus, and Eleutherococcus sessiliflorus inhabiting the ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-114425
更新日期:2018-01-01 00:00:00
abstract::This study aimed to elucidate the mechanisms of nuciferine (a main aporphine alkaloid of lotus leaf extract), which can induce relaxation in contracted tracheal rings. Under Ca2+-free and 2 mM Ca2+ conditions, we found that nuciferine had no effect on the resting muscle tone of tracheal rings. In contrast, nuciferine ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-118178
更新日期:2018-01-01 00:00:00
abstract::A MeOH extract prepared from culture of an actinomycete Streptomyces sp. HZP-2216E isolated from marine green algae Ulva pertusa was found to significantly inhibit proliferation of human glioma cells. Two different media were applied to culture this marine actinomycete, which produced two new compounds of 23-O-butyryl...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-111897
更新日期:2017-12-01 00:00:00
abstract::Hyperuricemia is a clinical condition characterized by an elevated level of serum uric acid and is a key risk factor for the development of gout and metabolic disorders. The existing urate-lowering therapies are often impractical for certain patient populations, providing a rationale to explore new agents with improve...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-111012
更新日期:2017-11-01 00:00:00