A Review of the Toxicity of Compounds Found in Herbal Dietary Supplements.

abstract：:Mammea-type coumarins are a particular type of secondary metabolites biosynthesized by the tropical rainforest tree Calophyllum Brasiliense, which is distributed from South America to Mexico. Particularly, mammea A/BA and A/BB (alone or as a mixture) possess biological properties such as cytotoxic and antitumoral acti...

journal_title：Planta medica

authors： Gómez-Verjan JC,Rivero-Segura NA,Estrella-Parra E,Rincón-Heredia R,Madariaga-Mazón A,Flores-Soto E,González-Meljem M,Cerbón M,Reyes-Chilpa R

更新日期：2019-01-01 00:00:00

abstract：:A callus was induced from the petiole of Panax ginseng C. A. Meyer by treatment with 2,4-D. The callus has been maintained on the synthetic media containing 2,4-D as growth factor. Habituated ginseng callus which required no auxin for its growth was induced from a 2,4-D callus by successive treatments with a low conce...

journal_title：Planta medica

authors： Furuya T,Yoshikawa T,Ishii T,Kajii K

更新日期：1983-03-01 00:00:00

abstract：:Genome sequencing provides new opportunities and challenges for identifying genes for the biosynthesis of secondary metabolites. A putative biosynthetic gene cluster of fumigaclavine C, an ergot alkaloid of the clavine type, was identified in the genome sequence of ASPERGILLUS FUMIGATUS by a bioinformatic approach. Th...

journal_title：Planta medica

authors： Li SM,Unsöld IA

更新日期：2006-10-01 00:00:00

abstract：:Cuttings of a clone of A. annua L. (Asteraceae), grown under 16 h photoperiod for 55 days were transferred to six photoperiod treatments in the greenhouse. Under short photoperiods (8, 10, or 12 h), plants flowered after two weeks; plants under long photoperiods (16, 20, or 24 h) remained vegetative until termination ...

journal_title：Planta medica

authors： Ferreira JF,Simon JE,Janick J

更新日期：1995-04-01 00:00:00

abstract：:Three new lycopodium alkaloids, 11alpha-hydroxyphlegmariurine B (2), 7alpha-hydroxyphlegmariurine B (3) and 7alpha,11alpha-dihydroxyphlegmariurine B (4) along with a known compound, phlegmariurine B (1), were isolated from the herb Huperzia serrata. The structures of the above compounds were elucidated based on spectr...

journal_title：Planta medica

authors： Tan CH,Wang BD,Jiang SH,Zhu DY

更新日期：2002-02-01 00:00:00

abstract：:Pancreatic cancer is one of the most aggressive human malignancies with an increasing incidence worldwide. In addition to the poor survival rates, combinations using gemcitabine as a backbone have failed to show any benefit beyond monotherapy. These facts underscore an urgent need for novel therapeutic options and mot...

journal_title：Planta medica

authors： Pinto-Garcia L,Efferth T,Torres A,Hoheisel JD,Youns M

更新日期：2010-08-01 00:00:00

abstract：:When added to suspension cultures of CATHARANTHUS ROSEUS, abscisic acid (ABA) stimulated intracellular accumulation of the indole alkaloids catharanthine and ajmalicine in both flask and 30 litre fermenter-scale systems. The response varied, and depended upon the cell line, the concentration and source of the ABA, and...

journal_title：Planta medica

authors： Smith JI,Smart NJ,Kurz WG,Misawa M

更新日期：1987-10-01 00:00:00

abstract：:A plant mixture containing extracts of Nigella sativa possesses blood glucose lowering effects, but the direct antidiabetic effect of Nigella sativa is not yet established. Therefore, the effect of Nigella sativa oil (NSO) on blood glucose concentrations was studied in streptozotocin diabetic rats. In addition, the ef...

journal_title：Planta medica

authors： El-Dakhakhny M,Mady N,Lembert N,Ammon HP

更新日期：2002-05-01 00:00:00

abstract：:The present study aimed to investigate standardized ethanol extracts of fruit and leaves of Piper sarmentosum for their in vivo antioxidant activity in rats using a CCl (4)-induced oxidative stress model. The standardization was based on the quantification of the markers pellitorine, sarmentine and sarmentosine by hig...

journal_title：Planta medica

authors： Hussain K,Ismail Z,Sadikun A,Ibrahim P

更新日期：2010-03-01 00:00:00

abstract：:We report the effects of aqueous extracts of the microalgae Dunaliella tertiolecta Butcher (Chlorophyceae) and Phaeodactylum tricornutum Bohlin (Bacillariophyceae) on oxotremorin-induced cholinergic symptoms, amphetamine-induced hypermotility, pentylenetetrazole-induced convulsions, and Rota-rod test performance. Both...

journal_title：Planta medica

authors： Laguna MR,Villar RM,Cadavid I,Calleja JM

更新日期：1990-04-01 00:00:00

abstract：:In natural product chemistry, it is often crucial to determine sugar composition as well as the absolute configuration of each monosaccharide in glycosides. An ultra-performance liquid chromatography method using both photodiode array (PDA) and mass spectrometry detectors (UPLC-UV/MS) was developed for qualitative ana...

journal_title：Planta medica

authors： Wang YH,Avula B,Fu X,Wang M,Khan IA

更新日期：2012-05-01 00:00:00

abstract：:A new activity of triterpenes and triterpenoid glycosides against phytovirus has been found. Based on the anti-TMV replication activity in vivo, 47 triterpenes and triterpenoid glycosides were screened through the leaf-disk method together with indirect ELISA. Structure-activity relationships were analyzed according t...

journal_title：Planta medica

authors： Zhang ZK,Ouyang MA,Wu ZJ,Lin QY,Xie LH

更新日期：2007-11-01 00:00:00

abstract：:Three previously undescribed natural products, phomopsinin A - C (1:  - 3: ), together with three known compounds, namely, cis-hydroxymellein (4: ), phomoxanthone A (5: ) and cytochalasin L-696,474 (6: ), were isolated from the solid culture of Phomopsis sp. CAM212, an endophytic fungus obtained from Garcinia xanthoch...

journal_title：Planta medica

authors： Jouda JB,Njoya EM,Fobofou SAT,Zhou ZY,Qiang Z,Mbazoa CD,Brandt W,Zhang GL,Wandji J,Wang F

更新日期：2020-09-01 00:00:00

abstract：:The investigation of the aerial parts of two collections of AMBROSIA MARITIMA afforded in addition to known pseudoguaianolides nine new ones including two nor-sesquiterpene lactones and two dimeric lactones. The structures were elucidated by highfield (1)H-NMR spectroscopy. ...

journal_title：Planta medica

authors： Jakupovic J,Sun H,Geerts S,Bohlmann F

更新日期：1987-02-01 00:00:00

abstract：:Croton caudatus is an important species in Dai folk medicine. Some other Croton species, in particular, C. kongensis, C. cascarilloides, C. crassifolius, C. lachnocarpus and C. olivaceus are often marketed as C. caudatus, and thus, the therapeutic effects of C. caudatus are not achieved. The respective morphological f...

journal_title：Planta medica

authors： Xue HG,Zhou SD,He XJ,Yu Y

更新日期：2007-06-01 00:00:00

abstract：:Cordatolide A and B were re-isolated from Calophyllum cordato-oblongum, an endemic species of Sri Lanka, and found to inhibit HIV-1 reverse transcriptase with IC50 values of 12.3 and 19.0 microM, respectively. ...

journal_title：Planta medica

authors： Dharmaratne HR,Wanigasekera WM,Mata-Greenwood E,Pezzuto JM

更新日期：1998-06-01 00:00:00

abstract：:In leaves of CONVALLARIA MAJALIS L. the cardenolide content is known to decrease towards the end of the vegetation period. However, at this stage the rate of biosynthesis is even higher than at the onset of flowering. This has been revealed by photosynthesis experiments in the presence of (14)CO (2) and the subsequent...

journal_title：Planta medica

authors： Schrutka-Rechtenstamm R,Kopp B,Löffelhardt W

更新日期：1985-10-01 00:00:00

abstract：:A new minor diterpenoid alkaloid, caeruline, was isolated from DELPHINIUM CAERULEUM Jacq. ex Camb. Its structure was elucidated as 1 on the basis of spectral evidence. Along with this new compound, three known diterpenoid alkaloids were also isolated from this plant and identified as tatsiensine, delcosine, and lycoct...

journal_title：Planta medica

authors： Pan YJ,Wang R,Chen SN,Chen YZ

更新日期：1993-02-01 00:00:00

abstract：:Targeted isolation based on a combination of NMR and HPLC-PDA-MS of a dichloromethane extract of Thymus vulgaris Varico 3 aerial parts afforded one new p-cymene dimer, 6,3',4'-trihydroxy-5,5'-diisopropyl-2,2'-dimethylbiphenyl (1: ), together with two known p-cymene derivatives (2: and 3: ), as well as five known compo...

journal_title：Planta medica

authors： Stefanis I,Hadjipavlou-Litina D,Bilia AR,Karioti A

更新日期：2019-08-01 00:00:00

abstract：:Based on the fact that Synadenium grantii is used in folk medicine for the treatment of peptic ulcers and inflammatory diseases, this work describes its chemical and pharmacological properties. Pharmacological investigation of the crude bark extract showed a high antioxidant activity over several scavenger systems, su...

journal_title：Planta medica

authors： Munhoz AC,Minozzo BR,Cruz LS,Oliveira TL,Machado WM,Pereira AV,Fernandes D,Manente FA,Vellosa JC,Nepel A,Barison A,Beltrame FL

更新日期：2014-04-01 00:00:00

abstract：:Barbaloin levels in the exudates from the leaves of 68 species of ALOE in the Kew collection have been determined by light absorption at 375 nm following separation by HPLC. The exudates from most species contained between 10-20% although a few concentrations of around 30% were found. The level in the leaf was usually...

journal_title：Planta medica

authors： Groom QJ,Reynolds T

更新日期：1987-08-01 00:00:00

abstract：:In Brazil, Plectranthus species are known as "boldo" and have been used in popular medicine for analgesic and dyspeptic purposes. Plectranthus need to be well identified in order to be used as commercially genuine medicinal plants. Here we describe AFLP DNA patterns able to distinguish among different Pectranthus spec...

journal_title：Planta medica

authors： Passinho-Soares H,Felix D,Kaplan MA,Margis-Pinheiro M,Margis R

更新日期：2006-08-01 00:00:00

abstract：:Acetonylgeraniin, an active principle isolated from the seeds of Euphoria longana Lam. (Sapindaceae), reversed the fall in arterial blood pressure in conscious hypertensive rats (SHRs) with orthostatic hypotension induced by injection of hexamethonium into animals subjected to 90 degrees head-up tilts for 60 seconds. ...

journal_title：Planta medica

authors： Hsu FL,Lu FH,Cheng JT

更新日期：1994-08-01 00:00:00

abstract：:Phytochemical investigations of the stem of Kadsura heteroclita (Roxb) Craib (Schizandraceae) resulted in the isolation and structure elucidation of six new triterpenoidal compounds named heteroclitalactones A-E (1-5) as well as heteroclic acid (6) and heteroclitalactone F (7), which was isolated for the first time fr...

journal_title：Planta medica

authors： Wang W,Liu J,Han J,Xu Z,Liu R,Liu P,Wang W,Ma X,Guan S,Guo D

更新日期：2006-04-01 00:00:00

abstract：:Five new xanthone glycosides, comastomasides A-E (1-5), were isolated from aqueous ethanol extracts of the aerial portions of Comastoma pedunculatum. The structures of these compounds were elucidated by spectroscopic analysis methods. Compounds 1-5 were evaluated for their hepatoprotective activity and cytotoxicity ag...

journal_title：Planta medica

authors： Qiao Y,Yuan Y,Cui B,Zhang Y,Chen H,Li S,Li Y

更新日期：2012-09-01 00:00:00

abstract：:Usnic acid, a lichen secondary metabolite produced by a whole number of lichens, has attracted the interest of researchers owing to its broad range of biological activity, including antiviral, antibiotic, anticancer properties, and it possessing a certain toxicity. The synthesis of new usnic acid derivatives and the i...

journal_title：Planta medica

authors： Dyrkheeva N,Luzina O,Filimonov A,Zakharova O,Ilina E,Zakharenko A,Kuprushkin M,Nilov D,Gushchina I,Švedas V,Salakhutdinov N,Lavrik O

更新日期：2019-01-01 00:00:00

abstract：:We previously reported that total coumarins, the major active components of Urtica dentata Hand, exhibited substantial protection against the development of autoimmune diabetes. Diabetic nephropathy is one of the most serious complications of diabetes and is closely correlated with end-stage renal disease. We used the...

journal_title：Planta medica

authors： Cao H,Ji Y,Li W,Liu Y,Fu R,Xiang M

更新日期：2015-10-01 00:00:00

abstract：:In an attempt to induce positive effects on the acclimatization of in vitro propagated Echinacea pallida, four arbuscular mycorrhizal (AM) fungi, Glomus mosseae, Gigaspora ramisporophora, Scutellospora fulgida and Entrophospora colombiana were selected to aid the soil adaptation process. Fungal inocula affected the su...

journal_title：Planta medica

authors： Lata H,De Andrade Z,Schaneberg B,Bedir E,Khan I,Moraes R

更新日期：2003-07-01 00:00:00

abstract：:Mulberroside A, a major stilbene constituent of MORUS ALBA L. (Moraceae), displays significant antitussive and antiasthmatic effects in animals. As part of our ongoing research on its biotransformation in rats, mulberroside A was orally administered to rats, and the metabolites in the gastrointestinal contents and fec...

journal_title：Planta medica

authors： Zhaxi M,Chen L,Li X,Komatsu K,Yao X,Qiu F

更新日期：2010-03-01 00:00:00

abstract：:Juniperus excelsa fruit essential oil as well as J. oxycedrus, Cedrus libani, and Pinus pinea wood essential oils have been obtained with yields between 2.2 ± 0.3 % to 3.4 ± 0.5 % and analyzed by gas chromatography. Sesquiterpenes mainly characterized C. libani and J. oxycedrus essential oils, while in P. pinea and J....

journal_title：Planta medica

authors： Saab AM,Guerrini A,Sacchetti G,Maietti S,Zeino M,Arend J,Gambari R,Bernardi F,Efferth T

更新日期：2012-12-01 00:00:00