Abstract:
:When added to suspension cultures of CATHARANTHUS ROSEUS, abscisic acid (ABA) stimulated intracellular accumulation of the indole alkaloids catharanthine and ajmalicine in both flask and 30 litre fermenter-scale systems. The response varied, and depended upon the cell line, the concentration and source of the ABA, and the growth phase at which the cells were treated. Precise timing of ABA addition to cells in a 301 fermenter resulted in a catharanthine yield of 85.25 mg/l after 10 days of cultivation. We propose that ABA may be useful for increasing the yield and reducing the production time for commercially useful secondary plant metabolites.
journal_name
Planta Medjournal_title
Planta medicaauthors
Smith JI,Smart NJ,Kurz WG,Misawa Mdoi
10.1055/s-2006-962775subject
Has Abstractpub_date
1987-10-01 00:00:00pages
470-4issue
5eissn
0032-0943issn
1439-0221journal_volume
53pub_type
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