Minor Alkaloids of Corydalis bulbosa, Structure of Bulbodione.

abstract：:Volatile oils of the leaves, fruits and stem-bark of CLEISTOPHOLIS PATENTS Engl. et Diels. (Annonacae) were analysed by means of gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of sixty-one components were identified; qualitative and quantitative differences in the oil composition wer...

journal_title：Planta medica

authors： Ekundayo O,Laakso I,Oguntimein B,Hiltunen R

更新日期：1988-08-01 00:00:00

abstract：:From the rhizome of Zingiber officinale L. (Zingiberaceae), four shogaols that protect IMR32 human neuroblastoma and normal human umbilical vein endothelial cells from beta-amyloid(25 - 35) insult at EC50 = 4.5 - 81 microM were isolated. The efficacy of cell protection from beta-amyloid(25 - 35) insult by these shogao...

journal_title：Planta medica

authors： Kim DS,Kim DS,Oppel MN

更新日期：2002-04-01 00:00:00

abstract：:Five new triterpenoid saponins (1-5) and four known triterpenoid saponins, ginsenoside Re5 (6), majonoside R1 (7), 24(R)-majonoside R1 (8), and ginsenoside Rf (9), were isolated from the rhizomes of Panacis majoris. The structures of new compounds were elucidated as (20S,24S,25R*)-6-O-[β-D-glucopyranosyl-(1 → 2)-β-D-g...

journal_title：Planta medica

authors： Li M,Liu F,Jin YR,Wang XZ,Wu Q,Liu Y,Li XW

更新日期：2017-02-01 00:00:00

abstract：:Five known abietane diterpenes, fatty acid esters of 7alpha-acyloxy-6beta-hydroxyroyleanone (1), grandidone A (2), 7alpha-acetoxy-6beta-hydroxyroyleanone (3), 6beta,7alpha-dihydroxyroyleanone (4), and coleon U (5), isolated from Plectranthus grandidentatus Gürke, were evaluated for their in vitro antiproliferative act...

journal_title：Planta medica

authors： Marques CG,Pedro M,Simões MF,Nascimento MS,Pinto MM,Rodríguez B

更新日期：2002-09-01 00:00:00

abstract：:Plant volatile organic compounds (volatiles) are secondary plant metabolites that play crucial roles in the reproduction, defence, and interactions with other vegetation. They have been shown to exhibit a broad range of biological properties and have been investigated for antimicrobial and anticancer activities. In ad...

journal_title：Planta medica

authors： Mun H,Townley HE

更新日期：2020-11-11 00:00:00

abstract：:The natural compound tyropeptin A, a new peptidyl aldehyde proteasome inhibitor, was tested for its trypanocidal activity in vitro using culture-adapted bloodstream forms of Trypanosoma brucei. The concentrations of tyropeptin A required to reduce the growth rate by 50 % and to kill all cells were 10 and 100 times low...

journal_title：Planta medica

authors： Steverding D,Pemberton AJ,Royle H,Spackman RW,Rivett AJ

更新日期：2006-06-01 00:00:00

abstract：:DNA sequence analysis of the rDNA internal transcribed spacer 1 (ITS1) and TaqMan real-time polymerase chain reaction were exploited for their applications in the differentiation of the traditional chinese medicinal plants euphorbia humifusa and e. maculata from three related adulterants e. hypericifolia, E. atoto and...

journal_title：Planta medica

authors： Xue HG,Wang H,Li DZ,Xue CY,Wang QZ

更新日期：2008-02-01 00:00:00

abstract：:One hundred and thirty-eight medicinal herbal drugs obtained from different suppliers were examined for microbial contaminants and for the detectability of pathogenic microorganisms. For this purpose, several microbiological standard parameters (total aerobic mesophilic count, enterobacteria, coliforms, aerobic sporef...

journal_title：Planta medica

authors： Czech E,Kneifel W,Kopp B

更新日期：2001-04-01 00:00:00

abstract：:Plumbagin, an active principle from Plumbaginaceous plants, produced a triphasic inotropic response (first positive, second negative, and third positive phases) in guinea-pig papillary muscle. The inotropic potency of plumbagin at the first positive phase was pD2 6.40, and the methylation of 5-hydroxy group of plumbag...

journal_title：Planta medica

authors： Itoigawa M,Takeya K,Furukawa H

更新日期：1991-08-01 00:00:00

abstract：:Targeted isolation based on a combination of NMR and HPLC-PDA-MS of a dichloromethane extract of Thymus vulgaris Varico 3 aerial parts afforded one new p-cymene dimer, 6,3',4'-trihydroxy-5,5'-diisopropyl-2,2'-dimethylbiphenyl (1: ), together with two known p-cymene derivatives (2: and 3: ), as well as five known compo...

journal_title：Planta medica

authors： Stefanis I,Hadjipavlou-Litina D,Bilia AR,Karioti A

更新日期：2019-08-01 00:00:00

abstract：:In order to evaluate the potency of novel antiviral drugs, 11 natural sulfated polysaccharides (SPs) from 10 green algae ( Enteromorpha compressa, Monostroma nitidum, Caulerpa brachypus, C. okamurai, C. scapelliformis, Chaetomorpha crassa, C. spiralis, Codium adhaerens, C. fragille, and C. latum) and 4 synthetic sulfa...

journal_title：Planta medica

authors： Lee JB,Hayashi K,Maeda M,Hayashi T

更新日期：2004-09-01 00:00:00

abstract：:Five compounds representative of major structural classes of lichen polyketides, VIZ. (+)-usnic (1), salazinic (2), vulpinic (3), gyrophoric (4), and evernic acids (5), were investigated for their ability to affect cell proliferation or wound healing, two functional targets of relevance for research on cancer or tissu...

journal_title：Planta medica

authors： Burlando B,Ranzato E,Volante A,Appendino G,Pollastro F,Verotta L

更新日期：2009-05-01 00:00:00

abstract：:This study aimed to elucidate the mechanisms of nuciferine (a main aporphine alkaloid of lotus leaf extract), which can induce relaxation in contracted tracheal rings. Under Ca2+-free and 2 mM Ca2+ conditions, we found that nuciferine had no effect on the resting muscle tone of tracheal rings. In contrast, nuciferine ...

journal_title：Planta medica

authors： Yang X,Yu MF,Lei J,Peng YB,Zhao P,Xue L,Chen W,Ma LQ,Liu QH,Shen J

更新日期：2018-01-01 00:00:00

abstract：:Ent-11alpha-hydroxy-16-kauren-15-one (1) induced apoptosis in a human leukemia cell line (HL-60 cells), however, the apoptosis-inducing properties of 1 and its related compounds remain to be proved. We examined the involvement of caspases, a family of cysteine aspartic proteases, which play a central role in induction...

journal_title：Planta medica

authors： Nagashima F,Kondoh M,Kawase M,Simizu S,Osada H,Fujii M,Watanabe Y,Sato M,Asakawa Y

更新日期：2003-04-01 00:00:00

abstract：:Novel therapies are needed to address the public health problem posed by methicillin-resistant STAPHYLOCOCCUS AUREUS (MRSA). In this study, we determined the effects of combinations of antibiotics and plant polyphenols against 20 clinical isolates of MRSA. The IN VITRO activities of 10 antibiotics and 15 natural polyp...

journal_title：Planta medica

authors： Lin RD,Chin YP,Hou WC,Lee MH

更新日期：2008-06-01 00:00:00

abstract：:Bioassay-guided fractionation of the roots of Ardisia cornudentata Mez (Myrsinaceae) led to the isolation of three new compounds, 3-methoxy-2-methyl-5-pentylphenol (1), 3-methoxy-2-methyl-5-(1'-ketopentyl)phenol (2), and cornudoside (3), together with twenty-six known compounds. Their structures were elucidated by ana...

journal_title：Planta medica

authors： Chang CP,Chang HS,Peng CF,Lee SJ,Chen IS

更新日期：2011-01-01 00:00:00

abstract：:The medicinal properties of curcumin obtained from Curcuma longa L. cannot be utilised because of poor bioavailability due to its rapid metabolism in the liver and intestinal wall. In this study, the effect of combining piperine, a known inhibitor of hepatic and intestinal glucuronidation, was evaluated on the bioavai...

journal_title：Planta medica

authors： Shoba G,Joy D,Joseph T,Majeed M,Rajendran R,Srinivas PS

更新日期：1998-05-01 00:00:00

abstract：:In this study the first supercritical fluid based protocol for the extraction, analysis, and isolation of six polar compounds, i.e., o-vanillin (1), styracin (2), vanillin (3), trans-cinnamic acid (4), vanillic acid (5), and shikimic acid (6), was developed. First, eight styrax resin products (R1-R8) obtained from var...

journal_title：Planta medica

authors： Scheuba J,Wronski VK,Rollinger JM,Grienke U

更新日期：2017-08-01 00:00:00

abstract：:Two new anthraquinones have been isolated from the seeds of PEGANUM HARMALA Linn and the structures established as 3,6-dihydroxy-8-methoxy-2-methylanthraquinone (peganone; 1) and 8-hydroxy-7-methoxy-2-methylanthraquinone (peganone; 2) by spectral correlations and chemical evidences. ...

journal_title：Planta medica

authors： Pitre S,Srivastava SK

更新日期：1987-02-01 00:00:00

abstract：:A procedure is described for the extraction of both anthraquinones and alkaloids from tissue culture material of CINCHONA species. Using this extraction method, it is possible to quantitatively determine the two groups of secondary metabolites produced in CINCHONA tissue cultures. ...

journal_title：Planta medica

authors： Wijnsma R,van Vliet TB,Harkes PA,van Groningen HJ,van der Heijden R,Verpoorte R,Svendsen AB

更新日期：1987-02-01 00:00:00

abstract：:Four new phenanthroindolizidine alkaloids, tylophoridicines C-F, together with three known ones, R-(+)-deoxytylophorinidine, tylophorinine and tylophorinidine, were isolated from the roots of Tylophora atrofolliculata. The structures were determined on the basis of spectral evidence. These alkaloids exhibited cytotoxi...

journal_title：Planta medica

authors： Huang X,Gao S,Fan L,Yu S,Liang X

更新日期：2004-05-01 00:00:00

abstract：:Silybum marianum Gaertn. (Milk thistle) has been used since ancient times for the relief of liver diseases characterized by intense oxidative stress such as inflammatory liver disease and cirrhosis. As oxidative stress by hyperglycemia is involved in micro- and macrovascular complications of type 2 diabetes, our aim w...

journal_title：Planta medica

authors： Palomino OM,Gouveia NM,Ramos S,Martín MA,Goya L

更新日期：2017-01-01 00:00:00

abstract：:Mulberroside A, a major stilbene constituent of MORUS ALBA L. (Moraceae), displays significant antitussive and antiasthmatic effects in animals. As part of our ongoing research on its biotransformation in rats, mulberroside A was orally administered to rats, and the metabolites in the gastrointestinal contents and fec...

journal_title：Planta medica

authors： Zhaxi M,Chen L,Li X,Komatsu K,Yao X,Qiu F

更新日期：2010-03-01 00:00:00

abstract：:This paper reports the phytochemical investigation of the 50% aq. EtOH extract of Houttuynia cordata, an effective TCM and functional food in China, which led to the isolation of 17 flavonoids including four new ones. The four new compounds were flavonoid derivatives tethered with houttuynin (3-oxododecanal). Each of ...

journal_title：Planta medica

authors： Chen SD,Li T,Gao H,Zhu QC,Lu CJ,Wu HL,Peng T,Yao XS

更新日期：2013-12-01 00:00:00

abstract：:This article outlines the development of a simple and specific analytical method for the quantitative determination of eight coumarin constituents from the methanolic extract of the roots of Angelica gigas. The coumarin constituents present in the roots of Angelica gigas were separated using an acetonitrile (0.1 % ace...

journal_title：Planta medica

authors： Avula B,Joshi VC,Reddy V L N,Choi YW,Khan IA

更新日期：2007-11-01 00:00:00

abstract：:The investigation of the roots and aerial parts of EUPATORIUM CANNABIUM afforded, in addition to the sesquiterpene lactones eupatolide, eupatoriopicrin, and eucannabinolide isolated previously, eight further lactones, three of which are new. Furthermore, in addition to known compounds, a new clerodane derivative and t...

journal_title：Planta medica

authors： Zdero C,Bohlmann F

更新日期：1987-04-01 00:00:00

abstract：:A MeOH extract prepared from culture of an actinomycete Streptomyces sp. HZP-2216E isolated from marine green algae Ulva pertusa was found to significantly inhibit proliferation of human glioma cells. Two different media were applied to culture this marine actinomycete, which produced two new compounds of 23-O-butyryl...

journal_title：Planta medica

authors： Zhang Z,Chen L,Zhang X,Liang Y,Anjum K,Chen L,Lian XY

更新日期：2017-12-01 00:00:00

abstract：:The leaves of Echinodorus grandiflorus are traditionally used in Brazil to treat several inflammatory conditions, including arthritis. This study aimed to investigate the antiarthritis activity of the 70% ethanol extract of E. grandiflorus leaves and a standardized flavonoid-rich fraction in an antigen-induced arthrit...

journal_title：Planta medica

authors： Garcia Ede F,de Oliveira MA,Candido LC,Coelho FM,Costa VV,Queiroz-Junior CM,Boff D,Amaral FA,de Souza Dda G,Teixeira MM,Braga FC

更新日期：2016-03-01 00:00:00

abstract：:Four isocedrenes (1:  - 4: ), including one new compound (2: ), were isolated from an ethanolic extract of the aerial parts of Perezia multiflora by bioactivity-guided fractionation. For compounds 1: and 3: , a revised stereochemical assignment is proposed based on molecular modeling studies using DFT-NMR calculations...

journal_title：Planta medica

authors： Bourgeade-Delmas S,André-Barrès C,Lucas J,Trinel M,Castillo Pareja D,Jullian V

更新日期：2020-11-23 00:00:00

abstract：:A contribution of the volatile oil from ginger rhizomes (Zingiber officinale Roscoe) on inhabiting the 5-HT3 receptor complex had been shown. In the present study a possible interaction of some compounds of the volatile oil with the 5-HT3 receptor system expressed in N1E-115 cells and with the serotoninergic system of...

journal_title：Planta medica

authors： Riyazi A,Hensel A,Bauer K,Geissler N,Schaaf S,Verspohl EJ

更新日期：2007-04-01 00:00:00