Five New Triterpenoid Saponins from the Rhizomes of Panacis majoris and Their Antiplatelet Aggregation Activity.

abstract：:The structure of albifloranine 1, a new alkaloid of ibogane type from the stem bark of Tabernaemontana albiflora (M IQ.) Pull. (Apocynaceae) has been determined. A detailed (1)H NMR study of albifloranine 1, coronaridine 2 and heyneanine 3 is presented. ...

journal_title：Planta medica

authors： Kan C,Husson HP,Kan SK,Lounasmaa M

更新日期：1981-01-01 00:00:00

abstract：:A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum....

journal_title：Planta medica

authors： Ahn KS,Sim WS,Lee IK,Seu YB,Kim IH

更新日期：1997-08-01 00:00:00

abstract：:The reactions of chloranil, fluoranil, 2,5 dichlorobenzoquinone and chloranilic acid with some alkaloids on thin layer chromatograms were examined with a view to determine their suitability as visualizing agents. Chloranil and 2,5 dichlorobenzoquinone (each 0.5% w/v in dioxan) were found to be most suitable as they ga...

journal_title：Planta medica

authors： Agarwal SP,Elsayed MA

更新日期：1982-08-01 00:00:00

abstract：:From the leaves of BLUMEA ARFAKIANA Martelli (Asteraceae), used in traditional medicine in Papua New Guinea, besides stigmasterol and beta-eudesmol, four graniline esters ( 1-4) have been isolated. Furthermore, blumealactone C ( 5), deacetylblumealactone C ( 6), and deoxyblumealactone C ( 7) have been identified. ...

journal_title：Planta medica

authors： Rücker G,Paulini G,Sakulas H,Lawong B,Goeltenboth F

更新日期：1991-06-01 00:00:00

abstract：:Aerial parts of Persicaria lapathifolia S.F. Gray (Polygonaceae) exhibited an inhibitory effect on superoxide production in unopsonized zymosan-stimulated human monocytes. Two known compounds, quercetin 3-O-beta-(2"-galloyl)-glucopyranoside and quercetin 3-O-beta-(2"-galloyl)-rhamnopyranoside, and a new compound, quer...

journal_title：Planta medica

authors： Kim Y,Jang DS,Park SH,Yun J,Min BK,Min KR,Lee HK

更新日期：2000-02-01 00:00:00

abstract：:Since the beginning of this century, Goji berries and juice are being sold as health food products in western countries and praised in advertisements and in the media for well-being and as an anti-aging remedy. The popularity of Goji products has rapidly grown over the last years thanks to efficient marketing strategi...

journal_title：Planta medica

authors： Potterat O

更新日期：2010-01-01 00:00:00

abstract：:Strictosidine synthase was partially purified from Catharanthus roseus cell suspension cultures and immobilized on CNBr-activated Sepharose. The immobilized enzyme exhibits a thermostability increased 300 fold over that of the soluble enzyme and catalyses exclusively the formation of the 3alpha(S)-isomer, strictosidin...

journal_title：Planta medica

authors： Pfitzner U,Zenk MH

更新日期：1982-09-01 00:00:00

abstract：:Extract of Tan-Shen (Salvia miltiorrhiza, Labiatae), a Chinese traditional crude drug, was reported to show beneficial activity for heart disease. Chemical examination on the extract was performed on the basis of screening for protective action on the ischemic myocardium. Isolated hearts were subjected to hypoxic perf...

journal_title：Planta medica

authors： Yagi A,Fujimoto K,Tanonaka K,Hirai K,Takeo S

更新日期：1989-02-01 00:00:00

abstract：:Flavonolignan compounds have been isolated from the fruits of SILYBUM MARIANUM subsp. ANATOLICUM and kaempferol 3-sulphate and other flavonoid compounds have been isolated from the aerial parts and were identified. The flavonoid sulphate derivatives are shown to be present in SILYBUM genus for the first time. ...

journal_title：Planta medica

authors： Meriçli AH

更新日期：1988-02-01 00:00:00

abstract：:Propolis has been reported to display a broad spectrum of biological activities such as anticancer, antioxidant, anti-inflammatory, antibiotic and antifungal properties, among others. There is great interest not only in the determination of the chemical composition of propolis but also in the understanding of the mech...

journal_title：Planta medica

authors： Tavares DC,Lira WM,Santini CB,Takahashi CS,Bastos JK

更新日期：2007-12-01 00:00:00

abstract：:In this study, the significant hepatoprotective effect of dioscin against CCl₄-induced acute liver damage in mice was first discovered, and the effect produced by dioscin at the dose of 100 mg/kg was equal to the action produced by silymarin at the dose of 200 mg/kg. Then, 1-dimension gel electrophoresis was used to s...

journal_title：Planta medica

authors： Lu B,Yin L,Xu L,Peng J

更新日期：2011-03-01 00:00:00

abstract：:In Brazil, Plectranthus species are known as "boldo" and have been used in popular medicine for analgesic and dyspeptic purposes. Plectranthus need to be well identified in order to be used as commercially genuine medicinal plants. Here we describe AFLP DNA patterns able to distinguish among different Pectranthus spec...

journal_title：Planta medica

authors： Passinho-Soares H,Felix D,Kaplan MA,Margis-Pinheiro M,Margis R

更新日期：2006-08-01 00:00:00

abstract：:Herpes simplex virus infections persist throughout the lifetime of the host and affect more than 80 % of the humans worldwide. The intensive use of available therapeutic drugs has led to undesirable effects, such as drug-resistant strains, prompting the search for new antiherpetic agents. Although diverse bioactivitie...

journal_title：Planta medica

authors： Nocchi SR,Companhoni MV,de Mello JC,Dias Filho BP,Nakamura CV,Carollo CA,Silva DB,Ueda-Nakamura T

更新日期：2017-04-01 00:00:00

abstract：:Phytochemical investigation of the dichloromethane extract of the leaves of Peltophorum pterocarpum, a tropical ornamental tree, led to the isolation of twelve compounds (1-12). One new derivative of peltogynoid ophioglonin (1) and a new 2-phenoxychromone (2) with its 3'-O-β-D-glucoside derivative (3) are described he...

journal_title：Planta medica

authors： Polasek J,Queiroz EF,Marcourt L,Meligova AK,Halabalaki M,Skaltsounis AL,Alexis MN,Prajogo B,Wolfender JL,Hostettmann K

更新日期：2013-04-01 00:00:00

abstract：:Chromatographically purified fractions of aqueous-ethanolic extracts from Baptisia tinctoria roots contained a strong lymphocyte DNA synthesis-stimulating activity. Electrophoretic analysis of these fractions revealed four distinct protein bands with molecular masses of P1 = 58 kD; P4 = 31 kD; P5 = 26 kD; and P6 = 14 ...

journal_title：Planta medica

authors： Beuscher N,Scheit KH,Bodinet C,Kopanski L

更新日期：1989-08-01 00:00:00

abstract：:The investigation of the aerial parts of two collections of AMBROSIA MARITIMA afforded in addition to known pseudoguaianolides nine new ones including two nor-sesquiterpene lactones and two dimeric lactones. The structures were elucidated by highfield (1)H-NMR spectroscopy. ...

journal_title：Planta medica

authors： Jakupovic J,Sun H,Geerts S,Bohlmann F

更新日期：1987-02-01 00:00:00

abstract：:Echinacea purpurea cell cultures have been established for the production of secondary and possibly bioactive compounds using elicitation techniques. Different elicitors including yeast elicitor, methyl jasmonate, glutathione, and manganese ions were used and compared for their effects on the formation of phenolics in...

journal_title：Planta medica

authors： Li WW,Barz W

更新日期：2006-02-01 00:00:00

abstract：:During activity-guided fractionations to screen for antineoplastic agents, further studies by means of preparative HPLC led to the isolation of four known furostanol saponins: protoneodioscin, protodioscin, protoneogracillin, protogracillin, along with their corresponding artifacts: methyl protoneodioscin, methyl prot...

journal_title：Planta medica

authors： Hu K,Dong A,Yao X,Kobayashi H,Iwasaki S

更新日期：1997-04-01 00:00:00

abstract：:Matrine and arsenic trioxide are monomers used in traditional Chinese medicine possessing anti-myeloma activities. In this study, we evaluated the effects and mechanisms of matrine, arsenic trioxide, and their combination therapy on the proliferation and apoptosis of the myeloma cell lines RPMI8226 and U266. The effec...

journal_title：Planta medica

authors： Yu Q,Chen B,Zhang X,Qian W,Ye B,Zhou Y

更新日期：2013-06-01 00:00:00

abstract：:Some enzymes of the terminal steps of phenylalanine and tyrosine biosyntheses were investigated in various alkaloid-forming ergot strains. All strains studied utilize both arogenate and phenylpyruvate as an intermediate in L-phenylalanine synthesis. L-Tyrosine is preferentially or exclusively synthesized via the aroge...

journal_title：Planta medica

authors： Schmauder HP,Gröger D

更新日期：1986-10-01 00:00:00

abstract：:Twelve phenolic compounds, including three stilbenes, two flavonoids, two coumarins, one neolignan, and four lignans, isolated from Euphorbia and Pycnanthus species or obtained by derivatization, were assayed for their potential antineoplastic efficacy in three human cancer cell lines: gastric (EPG85-257), pancreatic ...

journal_title：Planta medica

authors： Duarte N,Lage H,Abrantes M,Ferreira MJ

更新日期：2010-07-01 00:00:00

abstract：:Evidence supports the theory that bacterial communities colonizing Echinacea purpurea contribute to the innate immune enhancing activity of this botanical. Previously, we reported that only about half of the variation in in vitro monocyte stimulating activity exhibited by E. purpurea extracts could be accounted for by...

journal_title：Planta medica

authors： Haron MH,Tyler HL,Pugh ND,Moraes RM,Maddox VL,Jackson CR,Pasco DS

更新日期：2016-09-01 00:00:00

abstract：:Transformed root cultures of ipecac (Cephaelis ipecacuanha A. Richard), one of the recalcitrant woody plant species for Agrobacterium-mediated transformation, were established by co-culturing of in vitro petiole segments with Agrobacterium rhizogenes ATCC 15 834. Southern blot analysis of the established roots reveale...

journal_title：Planta medica

authors： Yoshimatsu K,Shimomura K,Yamazaki M,Saito K,Kiuchi F

更新日期：2003-11-01 00:00:00

abstract：:During the seasons 1989-1993, Valeriana officinalis plants were investigated for their contents of essential oil, valerenic acid and derivatives, and valepotriates. Harvesting of the subterranean parts was started in August of the year in which the seeds were sown, and continued until the last week of April of the sub...

journal_title：Planta medica

authors： Bos R,Woerdenbag HJ,van Putten FM,Hendriks H,Scheffer JJ

更新日期：1998-03-01 00:00:00

abstract：:A microdilution technique was developed for the assessment of in vitro cytotoxicity against KB cells derived from a human epidermoid carcinoma of the nasopharynx. The test was used to determine the cytotoxicity of a series of quassinoids, isolated from Brucea javanica, and which have previously been shown to demonstra...

journal_title：Planta medica

authors： Anderson MM,O'Neill MJ,Phillipson JD,Warhurst DC

更新日期：1991-02-01 00:00:00

abstract：:This perspective describes some commonly used animal models for the evaluation of potential chemopreventive agents in colon carcinogenesis. Special emphasis is given to the azoxymethane (AOM)/1,2-dimethylhydrazine (DMH) rat model and APCMIN mice, carrying a mutation in APC, a key gene in human carcinogenesis. In the A...

journal_title：Planta medica

authors： Femia AP,Caderni G

更新日期：2008-10-01 00:00:00

abstract：:Two new acylated secoiridoid glycosides were isolated from the aqueous acetone extract of the whole herb of Gentiana algida. The structures of these new products were established by spectral and chemical methods as 6'-(2,3-dihydroxybenzoyl)sweroside and 6'-(2,3-dihydroxybenzoyl)swertiamarin, respectively. ...

journal_title：Planta medica

authors： Tan RX,Hu J,Dong LD,Wolfender JL,Hostettmann K

更新日期：1997-12-01 00:00:00

abstract：:Cell Suspension cultures of THAMNOSMA MONTANA were grown in Gamborg B5 medium which was best suited for acridone alkaloid formation. From the lyophilized cell material nine acridones and three acridone-monoglucosides have been isolated which were found for the first time in the genus THAMNOSMA. Moreover, N-methylacrid...

journal_title：Planta medica

authors： Baumert A,Maier W,Matern U,Schmidt J,Schumann B,Gröger D

更新日期：1994-04-01 00:00:00

abstract：:Immune complex binding to macrophages was enhanced by treatment with an E. kansui extract. Systematic fractionation of the extract led to the characterization of 3-O-(2'E,4'Z-decadienoyl)- and 3-O-(2,3-dimethylbutyryl)-13- O-n-dodecanoyl-13-hydroxyingenol as the active principles. Immune complex binding to macrophages...

journal_title：Planta medica

authors： Matsumoto T,Cyong JC,Yamada H

更新日期：1992-06-01 00:00:00

abstract：:Antioxidants such as vitamin E may act differently on skin cells depending on the age of the skin and the level of oxidative damage induced. The effects of alpha-tocopherol (ATF) on H(2)O(2)-induced DNA damage and telomere shortening of normal human skin fibroblast cells derived from young and old individual donors we...

journal_title：Planta medica

authors： Makpol S,Zainuddin A,Rahim NA,Yusof YA,Ngah WZ

更新日期：2010-06-01 00:00:00