Immobilization of strictosidine synthase from Catharanthus cell cultures and preparative synthesis of strictosidine.

abstract：:One new diterpene, 2 alpha-hydroxy-12beta-hydroxy-isopimara-8(14), 15-diene, and six known compounds as triterpenes, sterols and fatty acid, were isolated from the stem bark of Tanaecium jaroba (Bignoniaceae), a Bolivian plant used in traditional medicine. Their structures were established mainly by 1D and 2D NMR (COS...

journal_title：Planta medica

authors： Mitaine-Offer AC,Sauvain M,Deharo E,Muñoz V,Zèches-Hanrot M

更新日期：2002-06-01 00:00:00

abstract：:This review describes the current status of the development of techniques combining liquid chromatography and nuclear magnetic resonance and their use in the context of natural products. HPLC-NMR methods have a rapidly growing impact on natural products research by enabling structure determination of natural products ...

journal_title：Planta medica

authors： Jaroszewski JW

更新日期：2005-08-01 00:00:00

abstract：:Tissue callus cultures originating from CHELIDONIUM MAJUS L. seeds were established on Gamborg B5, Murashige-Skoog (MS), and Schenk-Hildebrandt (SH) media. In all experimental conditions, calli accumulated a complex pattern of isoquinoline derivatives. The highest values, both in growth and in sanguinarine production,...

journal_title：Planta medica

authors： Colombo ML,Tomé F

更新日期：1991-10-01 00:00:00

abstract：:Mulberroside A, a major stilbene constituent of MORUS ALBA L. (Moraceae), displays significant antitussive and antiasthmatic effects in animals. As part of our ongoing research on its biotransformation in rats, mulberroside A was orally administered to rats, and the metabolites in the gastrointestinal contents and fec...

journal_title：Planta medica

authors： Zhaxi M,Chen L,Li X,Komatsu K,Yao X,Qiu F

更新日期：2010-03-01 00:00:00

abstract：:A simple and efficient method for the separation of the three phenolic diketones, curcumin 1, demethoxycurcumin 2, and bis-demethoxycurcumin 3, isolated from the rhizomes of Curcuma longa has been developed. The method is of general applicability for the separation of compounds containing acidic and chelating groups a...

journal_title：Planta medica

authors： Rasmussen HB,Christensen SB,Kvist LP,Karazmi A

更新日期：2000-05-01 00:00:00

abstract：:Averrhoa bilimbi Linn. fruit and its extracts were screened for antihypercholesterolemic activity using Triton-induced hypercholesterolemia in rats as a model. The fruit and its water extract, but not alcohol and hexane extracts, showed remarkable antihypercholesterolemic activity. An active fraction, which showed act...

journal_title：Planta medica

authors： Ambili S,Subramoniam A,Nagarajan NS

更新日期：2009-01-01 00:00:00

abstract：:In the course of our investigations on Umutambasha in order to identify its convulsant principles, small quantities of monofluoroacetate were observed in stem bark, leaves, and fruits of this plant newly identified as Dichapetalum michelsonii Hauman. Conclusive evidence for a monofluoroacetate presence came from its i...

journal_title：Planta medica

authors： Esters V,Karangwa C,Tits M,Francotte P,Pirotte B,Servais AC,Fillet M,Crommen J,Robbrecht E,Minet A,Grisar T,Angenot L,Frederich M

更新日期：2013-03-01 00:00:00

abstract：:New phloroglucinol derivatives were isolated from the ethanolic extract of ECKLONIA MAXIMA, a brown alga found off the west coast of South Africa. Most of these compounds contain dibenzo[1,4]dioxin elements. The common basic unit of all the compounds found is eckol, a hexahydroxyphenoxydibenzo[1,4]dioxin composed of 3...

journal_title：Planta medica

authors： Glombitza KW,Vogels HP

更新日期：1985-08-01 00:00:00

abstract：:Ginsenoside Ro, an oleanane-type saponin has been screened for activity in experimental models of acute and chronic hepatitis. Ginsenoside Ro (50 and 200 mg/kg, P.O.) inhibited the increase of serum glutamic oxaloacetic transaminase (s-GOT) and serum glutamic pyruvic transaminase (s-GPT) levels in D-galactosamine (Gal...

journal_title：Planta medica

authors： Matsuda H,Samukawa K,Kubo M

更新日期：1991-12-01 00:00:00

abstract：:A pyrolytic gaschromatographic process was developed for the routine assay of both cyclodextrin inclusion complexes, and for the differentiation of the mechanical mixture of the same oil with beta-cyclodextrin. The method is a direct assay of low material demand. ...

journal_title：Planta medica

authors： Pobozsny K,Kernóczi L,Tétényi P,Héthelyi I,Szejtli J

更新日期：1981-07-01 00:00:00

abstract：:In Brazil, Plectranthus species are known as "boldo" and have been used in popular medicine for analgesic and dyspeptic purposes. Plectranthus need to be well identified in order to be used as commercially genuine medicinal plants. Here we describe AFLP DNA patterns able to distinguish among different Pectranthus spec...

journal_title：Planta medica

authors： Passinho-Soares H,Felix D,Kaplan MA,Margis-Pinheiro M,Margis R

更新日期：2006-08-01 00:00:00

abstract：:Flavonoids are metabolized in vivo to monocyclic phenolic acids. We investigated whether 18 phenolic acids of the benzoic, phenylacetic, phenylpropanoic or cinnamic series-known or potential metabolites of flavonoids-inhibit reactive oxygen species (ROS) released by human polymorphonuclear neutrophils (PMNs). Chemilum...

journal_title：Planta medica

authors： Limasset B,Ojasoo T,le Doucen C,Doré JC

更新日期：1999-02-01 00:00:00

abstract：:The benzophenanthridine alkaloids sanguinarine and chelerythrine of Chelidonium majus, L. (Papaveraceae), are potent inhibitors of 5-lipoxygenase in polymorphonuclear leukocytes and 12-lipoxygenase in mouse epidermis, while the activity of soybean lipoxygenase is not influenced. The extract of the herb of Ch.majus als...

journal_title：Planta medica

authors： Vavrecková C,Gawlik I,Müller K

更新日期：1996-10-01 00:00:00

abstract：:Bioactivity-guided fractionations for ACAT inhibitor led to the isolation of guineensine from the CHCl (3) extract of Piper longum. Its structure was identified by spectroscopic means (IR, UV, MS and NMR). Guineensine inhibited ACAT activity in a dose-dependent manner with an IC (50) value of 3.12 micro M. ...

journal_title：Planta medica

authors： Lee SW,Rho MC,Nam JY,Lim EH,Kwon OE,Kim YH,Lee HS,Kim YK

更新日期：2004-07-01 00:00:00

abstract：:The alkaloidal content of of the stem barks of Hernandia cordigera has been studied and compared to that of other Hernandia species. Main alkaloids are phenolic aporphines. ...

journal_title：Planta medica

authors： Lavault M,Debray MM,Bruneton J

更新日期：1981-05-01 00:00:00

abstract：:The species Ageratina pichinchensis (Asteraceae) has been used for a long time in Mexican traditional medicine for the treatment of different skin conditions and injuries. In this study, the healing capacity of the plant extracts obtained was evaluated and, in order to understand the mechanism of healing, we also anal...

journal_title：Planta medica

authors： Romero-Cerecero O,Zamilpa-Álvarez A,Ramos-Mora A,Alonso-Cortés D,Jiménez-Ferrer JE,Huerta-Reyes ME,Tortoriello J

更新日期：2011-07-01 00:00:00

abstract：:From the roots of UNCARIA TOMENTOSA six oxindol alkaloids have been isolated and identified as isopteropodin, pteropodin, mitraphyllin, isomitraphyllin, rynchophyllin and isorynchophyllin. By ion pair chromatography on HPLC a fingerprint analysis has been worked out which allowed to differentiate between various UNICA...

journal_title：Planta medica

authors： Wagner H,Kreutzkamp B,Jurcic K

更新日期：1985-10-01 00:00:00

abstract：:We report the effects of aqueous extracts of the microalgae Dunaliella tertiolecta Butcher (Chlorophyceae) and Phaeodactylum tricornutum Bohlin (Bacillariophyceae) on oxotremorin-induced cholinergic symptoms, amphetamine-induced hypermotility, pentylenetetrazole-induced convulsions, and Rota-rod test performance. Both...

journal_title：Planta medica

authors： Laguna MR,Villar RM,Cadavid I,Calleja JM

更新日期：1990-04-01 00:00:00

abstract：:Increasingly, as a result of recent biochemical work, there exists a realistic possibility of taking a molecular genetic approach to the manipulation of alkaloid-producing pathways in plant tissue cultures. In the pathways forming indole alkaloids in CATHARANTHUS ROSEUS, tropane alkaloids in DATURA and HYOSCYAMUS spec...

journal_title：Planta medica

authors： Robins RJ,Waltons NJ,Hamill JD,Parr AJ,Rhodes MJ

更新日期：1991-10-01 00:00:00

abstract：:Crocin is a pharmacologically active component of Crocus sativus. It is an unusual water-soluble carotenoid responsible for the red color of saffron. In various studies, the anticancer effect of saffron and its constituents has been established. Polyethylene glycolated nanoliposomes with a size range up to 200 nm are ...

journal_title：Planta medica

authors： Rastgoo M,Hosseinzadeh H,Alavizadeh H,Abbasi A,Ayati Z,Jaafari MR

更新日期：2013-04-01 00:00:00

abstract：:Stem extracts of Styrax camporum Pohl and Caesalpinia ferrea Martius were administered orally and intraperitoneally to rats and effected a decrease in the acute ulceration number. The volume, pH, and hydrochloric acid concentration of gastric secretions were measured after administration of both extracts, atropine, an...

journal_title：Planta medica

authors： Bacchi EM,Sertié JA

更新日期：1994-04-01 00:00:00

abstract：:The fruits of OSTEOPHLOEUM PLATYSPERMUM (Myristicaceae) contain sitosterol, eperu-8(20),13-dien-3alpha,15-diol, glyceryl laurodimyristate, glyceryl 1,3-lauromyristate and five neolignans: dihydroguaiaretic acid, hydroxyotobain, hydroxyoxootobain, guaiacin and otobaphenol. ...

journal_title：Planta medica

authors： Fo RB,de Carvalho MG,Gottlieb OR

更新日期：1984-02-01 00:00:00

abstract：:Scientific achievements in the last two decades have revolutionized the treatment and prevention of breast cancer. This is mainly because of targeted therapies and a better understanding of the relationship between estrogen, its receptor, and breast cancer. One of these discoveries is the use of synthetic selective es...

journal_title：Planta medica

authors： Oseni T,Patel R,Pyle J,Jordan VC

更新日期：2008-10-01 00:00:00

abstract：:The inhibitory action of the major constituent of Sebastiania schottiana (Euphorbiaceae), 2-hydroxy-4,6-dimethoxyacetophenone (xanthoxyline) on contractions induced by agonists and electrical stimulation of smooth and cardiac muscle preparations was analysed. Xanthoxyline (30 to 300 microM) inhibited contractions of t...

journal_title：Planta medica

authors： Calixto JB,Miguel OG,Yunes RA,Rae GA

更新日期：1990-02-01 00:00:00

abstract：:A quantitative analysis using (1)H-NMR (Q-NMR) has been developed for the determination of strychnine and brucine in Strychnos nux-vomica seeds and stems. The advantages of the method are that no reference alkaloids are needed for calibration curves, the quantification could be directly realized on a crude extract, st...

journal_title：Planta medica

authors： Frédérich M,Choi YH,Verpoorte R

更新日期：2003-12-01 00:00:00

abstract：:The present study is aimed at evaluating the effects of luteolin on the scratching behavior associated with an allergic cutaneous reaction in mice. Elicitation of passive cutaneous anaphylaxis, and intradermal injections of compound 48/80, histamine or serotonin induced scratching behavior in ICR mice. Models of irrit...

journal_title：Planta medica

authors： Baolin L,Weiwei W,Ning T

更新日期：2005-05-01 00:00:00

abstract：:Leaves of Ligustrum vulgare (common privet) have been used for treatment of oropharyngeal inflammations or as antirheumatic, diuretic, and hypotensive agents in folk medicine in southern Europe. Taking into account that neutrophils are involved in the inflammation, the aim of the study was to determine the effect of a...

journal_title：Planta medica

authors： Czerwińska ME,Granica S,Kiss AK

更新日期：2013-07-01 00:00:00

abstract：:Two new depsides as well as the known p-hydroxybenzoic acid and its methyl ester, protocatechuic acid, 2-(4-hydroxyphenyl)-ethanol, 2-(3,4-dihydroxyphenyl)-ethanol and the flavonoids kaempferol, quercetin, luteolin and hypolaetin and the glycosides 3- O-beta- D-glucopyranosylquercetin (isoquercitrine), 3- O-beta- D-gl...

journal_title：Planta medica

authors： Hillenbrand M,Zapp J,Becker H

更新日期：2004-04-01 00:00:00

abstract：:The phenylpropanoid dibenzylbutyrolactone lignan arctigenin, a key component found in Arctium lappa, or burdock, has been reported with a variety of therapeutic effects including anticancer, anti-inflammation, and antivirus effects. Using LC/MS/MS, three novel metabolites of arctigenin, namely, arctigenic acid, arctig...

journal_title：Planta medica

authors： Gao Q,Zhang Y,Wo S,Zuo Z

更新日期：2013-04-01 00:00:00

abstract：:Six new pyrrolizidine alkaloids, a new carboxylic acid, a new phenolic and a new oleanane glycoside, together with the known compounds 7,7'-bis-(4-hydroxy-3,5-dimethoxyphenyl)-8,8'-dihydroxymethyltetrahydrofuran 4'-O-beta-D-glucopyranoside, rosmarinic acid, caffeic acid, tormentic acid 28-O-beta- D-glucopyranoside, eu...

journal_title：Planta medica

authors： Braca A,Bader A,Siciliano T,Morelli I,De Tommasi N

更新日期：2003-09-01 00:00:00