Quantitative analysis of strychnine and Brucine in Strychnos nux-vomica using 1H-NMR.

Abstract:

:A quantitative analysis using (1)H-NMR (Q-NMR) has been developed for the determination of strychnine and brucine in Strychnos nux-vomica seeds and stems. The advantages of the method are that no reference alkaloids are needed for calibration curves, the quantification could be directly realized on a crude extract, strychnine and brucine could easily be distinguished, an overall profile of the preparation (including non alkaloid compounds) could be directly obtained, and a very significant time-gain could be achieved, in comparison to conventional HPLC methods, for instance.

journal_name

Planta Med

journal_title

Planta medica

authors

Frédérich M,Choi YH,Verpoorte R

doi

10.1055/s-2003-818014

subject

Has Abstract

pub_date

2003-12-01 00:00:00

pages

1169-71

issue

12

eissn

0032-0943

issn

1439-0221

journal_volume

69

pub_type

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