New Pyrrolizidine Alkaloids and Glycosides from Anchusa strigosa.

abstract：:Two diterpenoids were prepared from hexane anti-inflammatory extracts of the Spanish herb Sideritis javalambrensis: ent-13-epi-12 alpha-acetoxymanoyl oxide (= "manoyl oxide F1") and ent-8 alpha-hydroxy-labda-13(16), 14-diene (= "labdane F2"). They were evaluated for possible anti-inflammatory actions in vitro in the c...

journal_title：Planta medica

authors： de las Heras B,Hoult JR

更新日期：1994-12-01 00:00:00

abstract：:Eight iridoid glucosides have been isolated from Euphrasia rostkoviana by the combination of open column- and high performance liquid chromatography. The structure of a new compound, named eurostoside, and the identity of the others have been established by chemical transformations and spectral evidence of the compoun...

journal_title：Planta medica

authors： Salama O,Sticher O

更新日期：1983-02-01 00:00:00

abstract：:Ginsenoside Ro, an oleanane-type saponin has been screened for activity in experimental models of acute and chronic hepatitis. Ginsenoside Ro (50 and 200 mg/kg, P.O.) inhibited the increase of serum glutamic oxaloacetic transaminase (s-GOT) and serum glutamic pyruvic transaminase (s-GPT) levels in D-galactosamine (Gal...

journal_title：Planta medica

authors： Matsuda H,Samukawa K,Kubo M

更新日期：1991-12-01 00:00:00

abstract：:The aim of this study was to investigate the anti-asthmatic effects of Perilla seed oil in vitro and in vivo in sensitized guinea pigs. Aerosolized antigen caused an immediate bronchoconstriction. Perilla seed oil per os inhibited the increase in lung resistance and the decrease in dynamic lung compliance in a dose-de...

journal_title：Planta medica

authors： Deng YM,Xie QM,Zhang SJ,Yao HY,Zhang H

更新日期：2007-01-01 00:00:00

abstract：:The major alkaloids of PAPAVER TRINIIFOLIUM collected in two different parts of Anatolia have proved to be of the aporphine, morphinane and rhoeadine types. The two collections possessed different major alkaloids and the existence of chemical strains is indicated. In addition to the aporphine-(floripavidine), the morp...

journal_title：Planta medica

authors： Sariyar G

更新日期：1983-09-01 00:00:00

abstract：:We present the application of the generative topographic map algorithm to visualize the chemical space populated by natural products and synthetic drugs. Generative topographic maps may be used for nonlinear dimensionality reduction and probabilistic modeling. For compound mapping, we represented the molecules by two-...

journal_title：Planta medica

authors： Miyao T,Reker D,Schneider P,Funatsu K,Schneider G

更新日期：2015-04-01 00:00:00

abstract：:In our previous study, we reported the interesting in vitro antiplasmodial activity of some Rwandan plant extracts. This gave rise to the need for these extracts to also be evaluated in vivo and to identify the compounds responsible for their antiplasmodial activity. The aim of our study was, on the one hand, to evalu...

journal_title：Planta medica

authors： Muganga R,Angenot L,Tits M,Frédérich M

更新日期：2014-04-01 00:00:00

abstract：:Three new lycopodium alkaloids, 11alpha-hydroxyphlegmariurine B (2), 7alpha-hydroxyphlegmariurine B (3) and 7alpha,11alpha-dihydroxyphlegmariurine B (4) along with a known compound, phlegmariurine B (1), were isolated from the herb Huperzia serrata. The structures of the above compounds were elucidated based on spectr...

journal_title：Planta medica

authors： Tan CH,Wang BD,Jiang SH,Zhu DY

更新日期：2002-02-01 00:00:00

abstract：:Thalivarmine and thalsivasine, together with the known bases thalmelatidine, thalicberine, O-methylthalicberine, thaliphylline, thalmethine, O-methylthalmethine and (-)- N-methylcanadine have been isolated from the above ground parts of THALICTRUM MINUS var. MINUS L. ...

journal_title：Planta medica

authors： Başer KH,Kinmer N

更新日期：1985-10-01 00:00:00

abstract：:Three new glycosides, 1,4,8-trihydroxynaphthalene-1-O-D-glucopyranosyl-(1-->6)-beta-D- xylopyranoside (1), 1,4,8-trihydroxynaphthalene-1-O-beta-D-glucopyranosyl-(1-->6)-alph a-L- arabinopyranoside (2), 1-hydroxy-4-methoxynaphthalene-1-O-beta-D-glucopyranosyl-(1-->6)- alpha-L-rhamnopyranoside (3), were isolated from th...

journal_title：Planta medica

authors： Lee SW,Lee KS,Son JK

更新日期：2000-03-01 00:00:00

abstract：:As an exploratory investigation of antimicrobial promoting compounds, 3- O-acyl-(-)-epicatechins and 3- O-acyl-(+)-catechins possessing various aromatic groups and aliphatic chains of varying length from C4 to C16 for increasing lipophilicity were synthesized and tested for antimicrobial activities against Gram-positi...

journal_title：Planta medica

authors： Park KD,Park YS,Cho SJ,Sun WS,Kim SH,Jung DH,Kim JH

更新日期：2004-03-01 00:00:00

abstract：:Reduced estrogen levels occurring during menopause in woman are accompanied by a variety of disorders, e. g., hot flushes, depressions, osteoporosis, increase of body weight, and reduced movement drive. In this study we investigated the combined effects of physical activity, estradiol substitution, and a phytoestrogen...

journal_title：Planta medica

authors： Hertrampf T,Degen GH,Kaid AA,Laudenbach-Leschowsky U,Seibel J,Di Virgilio AL,Diel P

更新日期：2006-05-01 00:00:00

abstract：:We have isolated five furanocoumarins, byakangelicin, phellopterin, imperatorin, isoimperatorin, and oxypeucedanin methanolate, from the roots of Angelica dahurica (Umbelliferae) and prepared five semi-synthesized compounds by the partial reduction of each isolated furanocoumarin, and the effects of these compounds on...

journal_title：Planta medica

authors： Ban HS,Lim SS,Suzuki K,Jung SH,Lee S,Lee YS,Shin KH,Ohuchi K

更新日期：2003-05-01 00:00:00

abstract：:Three new xanthones, 22,23-dihydroxydihydrogambogenic acid (1), 12-hydroxygambogefic acid A (2), and hanburixanthone (3), along with thirteen known compounds were isolated from the resin of Garcinia hanburyi. The structures of the new compounds were determined by detailed analysis of 1D and 2D NMR spectra and by compa...

journal_title：Planta medica

authors： Deng YX,Guo T,Shao ZY,Xie H,Pan SL

更新日期：2013-06-01 00:00:00

abstract：:Northern Labrador tea, Rhododendron tomentosum ssp. subarcticum, is one of the most commonly used medicinal plants by Inuit and other First Nations peoples of Canada. The phenolic profile and seasonal variation of this commonly used medicinal plant remains largely unknown. To assess optimal harvesting time, R. tomento...

journal_title：Planta medica

authors： Black P,Saleem A,Dunford A,Guerrero-Analco J,Walshe-Roussel B,Haddad P,Cuerrier A,Arnason JT

更新日期：2011-09-01 00:00:00

abstract：:The therapeutic goal in liver fibrosis is the reversal of fibrosis and the selective clearance of activated hepatic stellate cells (HSCs) by inducing apoptosis. Over the past several years, we have screened for natural products that mediate apoptosis in activated HSCs. Among the candidate compounds, honokiol, isolated...

journal_title：Planta medica

authors： Park EJ,Zhao YZ,Kim YH,Lee BH,Sohn DH

更新日期：2005-01-01 00:00:00

abstract：:Two indole alkaloids were isolated from the culture of Aspergillus fumigatus (strain No. CY018), an endophytic fungus harboring inside the elder leaf of Cynodon dactylon. These two chemicals were identified as fumigaclavine C and fumitremorgin C. In screening the bioactivity of these two indole alkaloids, their vasore...

journal_title：Planta medica

authors： Ma HY,Song YC,Mao YY,Jiang JH,Tan RX,Luo L

更新日期：2006-04-01 00:00:00

abstract：:Mammea-type coumarins are a particular type of secondary metabolites biosynthesized by the tropical rainforest tree Calophyllum Brasiliense, which is distributed from South America to Mexico. Particularly, mammea A/BA and A/BB (alone or as a mixture) possess biological properties such as cytotoxic and antitumoral acti...

journal_title：Planta medica

authors： Gómez-Verjan JC,Rivero-Segura NA,Estrella-Parra E,Rincón-Heredia R,Madariaga-Mazón A,Flores-Soto E,González-Meljem M,Cerbón M,Reyes-Chilpa R

更新日期：2019-01-01 00:00:00

abstract：:Phytochemical investigations of the stem of Kadsura heteroclita (Roxb) Craib (Schizandraceae) resulted in the isolation and structure elucidation of six new triterpenoidal compounds named heteroclitalactones A-E (1-5) as well as heteroclic acid (6) and heteroclitalactone F (7), which was isolated for the first time fr...

journal_title：Planta medica

authors： Wang W,Liu J,Han J,Xu Z,Liu R,Liu P,Wang W,Ma X,Guan S,Guo D

更新日期：2006-04-01 00:00:00

abstract：:The hypoglycemic activity of olive leaf was studied. Maximum hypoglycemic activity was obtained from samples collected in the winter months, especially in February. One of the compounds responsible for this activity was oleuropeoside, which showed activity at a dose of 16 mg/kg. This compound also demonstrated antidia...

journal_title：Planta medica

authors： Gonzalez M,Zarzuelo A,Gamez MJ,Utrilla MP,Jimenez J,Osuna I

更新日期：1992-12-01 00:00:00

abstract：:Three new sauchinone analogues, sauchinones B-D (1-3), together with sauchinone (4), were isolated from the aerial part of Saururus chinensis. Structures of the new compounds were determined by extensive spectroscopic data as well as X-ray analysis. Compounds 3 and 4 inhibited nitric oxide production in lipopolysaccha...

journal_title：Planta medica

authors： Gao X,He J,Wu XD,Peng LY,Dong LB,Deng X,Li Y,Cheng X,Zhao QS

更新日期：2013-12-01 00:00:00

abstract：:Sungucine and isosungucine are two bisindole alkaloids isolated from the roots of the African plant Strychnos icaja Baillon. They both exhibit antiplasmodial activities but also show cytotoxic effects against human cancer cell lines. In order to elucidate their mechanism of action, we have investigated the interaction...

journal_title：Planta medica

authors： Lansiaux A,Bailly C,Houssier C,Colson P,De Pauw-Gillet MC,Frédérich M,Tits M,Angenot L

更新日期：2002-07-01 00:00:00

abstract：:The mechanism of action, leakage of cytochrome c from mitochondria into cytosol, for the antineoplastic compound glyfoline was examined. Additionally, our current studies revealed that glyfoline induced apoptotic changes and arrested cell cycle procession at the G2/M phase in nasopharyngeal carcinoma (NPC). A reverse ...

journal_title：Planta medica

authors： Su TL,Huang HM,Wang CK,Wu HC,Lin CT

更新日期：2005-01-01 00:00:00

abstract：:One new diterpene, 2 alpha-hydroxy-12beta-hydroxy-isopimara-8(14), 15-diene, and six known compounds as triterpenes, sterols and fatty acid, were isolated from the stem bark of Tanaecium jaroba (Bignoniaceae), a Bolivian plant used in traditional medicine. Their structures were established mainly by 1D and 2D NMR (COS...

journal_title：Planta medica

authors： Mitaine-Offer AC,Sauvain M,Deharo E,Muñoz V,Zèches-Hanrot M

更新日期：2002-06-01 00:00:00

abstract：:Three steroidal saponins, including astrogorgiosides A (1) and B (2) bearing acetamido-glucose moieties, and astrogorgioside C (3) with a 19-nor and bearing an aromatized B ring steroid aglycone, together with a known major saponin dimorphoside A (4), were obtained from the gorgonian Astrogorgia dumbea collected near ...

journal_title：Planta medica

authors： Lu YN,Cui P,Tian XQ,Lou LG,Fan CQ

更新日期：2016-06-01 00:00:00

abstract：:Isoliquiritigenin (4,2',4'-trihydroxychalcone, ISL) is a natural pigment with a simple chalcone structure. In this study, we report the ISL-induced inhibition on the growth of human hepatoma cells (Hep G2) for the first time. The cell growth inhibition achieved by ISL treatment resulted in programmed cell death in a c...

journal_title：Planta medica

authors： Hsu YL,Kuo PL,Lin LT,Lin CC

更新日期：2005-02-01 00:00:00

abstract：:The present study aimed to investigate standardized ethanol extracts of fruit and leaves of Piper sarmentosum for their in vivo antioxidant activity in rats using a CCl (4)-induced oxidative stress model. The standardization was based on the quantification of the markers pellitorine, sarmentine and sarmentosine by hig...

journal_title：Planta medica

authors： Hussain K,Ismail Z,Sadikun A,Ibrahim P

更新日期：2010-03-01 00:00:00

abstract：:Rhizomes of Actaea racemosa L. (formerly Cimicifuga racemosa) gained increasing interest as a plant-derived drug due to its hormone-like activity and the absence of estrogenic activity. According to the Current Good Manufacturing Practices guidelines and pharmacopeial standards, quality assessment of herbal starting m...

journal_title：Planta medica

authors： Bittner M,Krähmer A,Schenk R,Springer A,Gudi G,Melzig MF

更新日期：2017-08-01 00:00:00

abstract：:Genome sequencing provides new opportunities and challenges for identifying genes for the biosynthesis of secondary metabolites. A putative biosynthetic gene cluster of fumigaclavine C, an ergot alkaloid of the clavine type, was identified in the genome sequence of ASPERGILLUS FUMIGATUS by a bioinformatic approach. Th...

journal_title：Planta medica

authors： Li SM,Unsöld IA

更新日期：2006-10-01 00:00:00

abstract：:From the bulbs of Vietnamese Hippeastrum equestre Herb. (Amaryllidaceae), besides the well known alkaloids lycorine, tazettine, and hippeastrine, a new alkaloid, phamine, has been isolated. Its structure was established by spectroscopic methods. ...

journal_title：Planta medica

authors： Döpke W,Pham LH,Gründemann E,Bartoszek M,Flatau S

更新日期：1995-12-01 00:00:00