Effects of Phaeodactylum tricornutum and Dunaliella tertiolecta extracts on the central nervous system.

Abstract:

:We report the effects of aqueous extracts of the microalgae Dunaliella tertiolecta Butcher (Chlorophyceae) and Phaeodactylum tricornutum Bohlin (Bacillariophyceae) on oxotremorin-induced cholinergic symptoms, amphetamine-induced hypermotility, pentylenetetrazole-induced convulsions, and Rota-rod test performance. Both extracts significantly reduced rectal temperature, spontaneous motor activity, and time on the Rota-rod and increased the number of mice falling off the rod before 180 s, but neither protected against pentylenetetrazole-induced convulsions or against oxotremorin-induced tremor, salivation, and diarrhoea.

journal_name

Planta Med

journal_title

Planta medica

authors

Laguna MR,Villar RM,Cadavid I,Calleja JM

doi

10.1055/s-2006-960914

subject

Has Abstract

pub_date

1990-04-01 00:00:00

pages

152-7

issue

2

eissn

0032-0943

issn

1439-0221

journal_volume

56

pub_type

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