Abstract:
:An arabinogalactan-protein (AGP) from suspension culture medium of Malva sylvestris was isolated by precipitation with beta-glucosyl Yariv reagent, followed by gel-permeation chromatography. It revealed characteristic features of AGPs: a high amount of polysaccharide with a ratio of galactose to arabinose of 1.9 : 1, some uronic acids, and a small protein moiety with the main amino acids serine, alanine and hydroxyproline. The molecular weight was estimated to be 1.3 x 10(6) Da. Linkage analyses showed that the AGP is composed of a highly branched core polysaccharide of 3-, 6-, and 3,6-linked Galp residues with terminal Araf, GlcAp and Galp. Partial acid hydrolysis resulted in loss of Araf residues at the periphery of the molecule and heavily reduced its reactivity with beta-glucosyl Yariv antigen.
journal_name
Planta Medjournal_title
Planta medicaauthors
Classen B,Blaschek Wdoi
10.1055/s-2002-23127subject
Has Abstractpub_date
2002-03-01 00:00:00pages
232-6issue
3eissn
0032-0943issn
1439-0221journal_volume
68pub_type
杂志文章相关文献
PLANTA MEDICA文献大全abstract::Herbal medicine has been used to treat diseases for centuries; however, the biological active components and the mechanistic understanding of actions of plant-derived drugs are permanently discussed. MicroRNAs are a class of small, non-coding RNAs that play crucial roles as regulators of gene expression. In recent yea...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-0042-108450
更新日期:2016-08-01 00:00:00
abstract::Galphimine-B (G-B) is a bioactive compound isolated from the plant Galphimia glauca Cav. (Malpighiaceae) with central nervous system depressant properties previously described. In the present study, extracellular spiking activity records in either somatosensorial cortex or ventral tegmental area (VTA) neurons, were pe...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957440
更新日期:1998-05-01 00:00:00
abstract::As part of our continuing study on the Calophyllum species, a number of coumarins, xanthones and chromene acids from different Calophyllum species of Sri Lanka were tested for inhibitory activity against the HIV-1 and its virally-encoded reverse transcriptase (RT). These compounds were found to be inactive in both the...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-20058
更新日期:2002-01-01 00:00:00
abstract::Twelve phenolic compounds, including three stilbenes, two flavonoids, two coumarins, one neolignan, and four lignans, isolated from Euphorbia and Pycnanthus species or obtained by derivatization, were assayed for their potential antineoplastic efficacy in three human cancer cell lines: gastric (EPG85-257), pancreatic ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1240892
更新日期:2010-07-01 00:00:00
abstract::The investigation of the aerial parts of two collections of AMBROSIA MARITIMA afforded in addition to known pseudoguaianolides nine new ones including two nor-sesquiterpene lactones and two dimeric lactones. The structures were elucidated by highfield (1)H-NMR spectroscopy. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-962617
更新日期:1987-02-01 00:00:00
abstract::Emodin, chrysophanol and physcion have been shown to be the major anthraquinone pigments present in the dry roots of RUMEX ABYSINICA. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969640
更新日期:1984-02-01 00:00:00
abstract::Tryptanthrin and (E,Z)-3-(4-hydroxy-3,5-dimethoxybenzylidene)indolinone (indolinone) were recently isolated from Isatis tinctoria as potent anti-inflammatory and antiallergic alkaloids, and shown to inhibit COX-2, 5-LOX catalyzed leukotriene synthesis, and mast cell degranulation at low µM to nM concentrations. To ass...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0042-110323
更新日期:2016-08-01 00:00:00
abstract::In our investigation of in vitro antimalarial screening of medicinal herbal extracts, the n-BuOH extract from the root of Wikstroemia indica showed a potent inhibitory effect. Fractionation of the active extract led to the isolation of two biflavonoids, sikokianin B ( 1) and sikokianin C ( 2) with IC (50) values 0.54 ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2004-815462
更新日期:2004-01-01 00:00:00
abstract::Cuttings of a clone of A. annua L. (Asteraceae), grown under 16 h photoperiod for 55 days were transferred to six photoperiod treatments in the greenhouse. Under short photoperiods (8, 10, or 12 h), plants flowered after two weeks; plants under long photoperiods (16, 20, or 24 h) remained vegetative until termination ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-958040
更新日期:1995-04-01 00:00:00
abstract::The cytotoxicity and immunosuppressive activities of jaborosalactone-L and three 16 alpha-oxygenated withanolides from the leaves of Discopodium penninervium were studied. Jaborosalactone-L showed cytotoxicity only to the murine macrophage cell line, RAW 264.7, but the 16 alpha-oxygenated withanolides exhibited cytoto...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957594
更新日期:1997-02-01 00:00:00
abstract::Propagation of DIGITALIS LANATA by shoot tip culture made possible (a) the rapid multiplication of elite plants with the formation of plant clones and (b) the long-term cultivation of these plants which under normal growth conditions would die at the end of the second vegetation period. Optimum conditions were establi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960883
更新日期:1990-02-01 00:00:00
abstract::Two new triterpenoid saponins, along with five known ones, were isolated from the EtOH extract of the whole plants of Androsace umbellata. The structures of the new triterpenoid saponins were identified as 3- O-[ beta- D-xylopyranosyl-(1-->2)- beta- D-glucopyranosyl-(1-->4)-[ beta- D-glucopyranosyl-(1-->2)]- alpha- L-...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1081291
更新日期:2008-08-01 00:00:00
abstract::Ulcerative colitis is a chronic inflammatory condition whose treatment includes aminosalicylates, corticosteroids, and immunomodulators. Medicinal plants seem to be an important alternative treatment for this condition. They have been the subject of a great number of studies in recent years. This study was conducted t...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-0043-104933
更新日期:2017-05-01 00:00:00
abstract::Bioassay-guided fractionation of an MeCOEt extract of Frullania nisquallensis Sull. has furnished a DNA-damaging sesquiterpene, costunolide (1), and two inactive compounds, a sesquiterpene (-)-frullanolide (2) and a tridepside tenuiorin (3). (13)C-NMR data of 3 are reported. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957800
更新日期:1996-02-01 00:00:00
abstract::A new isoprenylated xanthone, cudrafrutixanthone A, was isolated from the roots of Cudrania fruticosa, together with 18 known compounds. Their structures were elucidated by spectroscopic methods. Most isoprenylated xanthones exhibited cytotoxicity against HCT-116, SMMC-7721, SGC-7901, and BGC-823 cell lines with IC (5...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-837829
更新日期:2005-03-01 00:00:00
abstract::A beta-hydroxychalcone 1, so far not reported as a natural compound, was separated from the diethyl ether extract of LEPTOSPERMUM SCOPARIUM (Myrtaceae). Furthermore, three known flavonoids 2-4 were isolated. The (13)C-NMR spectra of 2-4 are reported, since they have as yet not been reported in the literature. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959667
更新日期:1993-06-01 00:00:00
abstract::Five new compounds (1-5), including two limonoids, one triterpenoid, one steroid, and one sesquiterpenoid, along with nine known limonoids (6-14), were isolated from the bark of Melia azedarach. The structures of the new compounds were elucidated by 2D NMR spectroscopy and mass spectrometry. The isolated compounds as ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1328069
更新日期:2013-01-01 00:00:00
abstract::Volatile oils of the leaves, fruits and stem-bark of CLEISTOPHOLIS PATENTS Engl. et Diels. (Annonacae) were analysed by means of gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of sixty-one components were identified; qualitative and quantitative differences in the oil composition wer...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-962450
更新日期:1988-08-01 00:00:00
abstract::In this study, the significant hepatoprotective effect of dioscin against CCl₄-induced acute liver damage in mice was first discovered, and the effect produced by dioscin at the dose of 100 mg/kg was equal to the action produced by silymarin at the dose of 200 mg/kg. Then, 1-dimension gel electrophoresis was used to s...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1250461
更新日期:2011-03-01 00:00:00
abstract::Ischemic preconditioning, which is mediated by cell signaling molecules, protects the heart from ischemia-reperfusion injury by limiting the infarct size. Oleuropein, the main polyphenolic constituent of olives, reduced the infarct size in normal and cholesterol-fed rabbits when it was administered at a nutritional do...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0034-1383306
更新日期:2015-06-01 00:00:00
abstract::When added to suspension cultures of CATHARANTHUS ROSEUS, abscisic acid (ABA) stimulated intracellular accumulation of the indole alkaloids catharanthine and ajmalicine in both flask and 30 litre fermenter-scale systems. The response varied, and depended upon the cell line, the concentration and source of the ABA, and...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-962775
更新日期:1987-10-01 00:00:00
abstract::The therapy of type-2 diabetes mellitus is one of the major challenges of our age. A possible strategy to prevent the progression of this disease is the inhibition of protein tyrosine phosphatase 1B (PTP1B), a major negative regulator in the insulin and leptin signalling pathway. Phellodendri amurensis cortex is a wel...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0031-1280377
更新日期:2012-02-01 00:00:00
abstract::One hundred and thirty-eight medicinal herbal drugs obtained from different suppliers were examined for microbial contaminants and for the detectability of pathogenic microorganisms. For this purpose, several microbiological standard parameters (total aerobic mesophilic count, enterobacteria, coliforms, aerobic sporef...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-12007
更新日期:2001-04-01 00:00:00
abstract::A study of secondary metabolites from the bark of Alnus glutinosa led to the isolation of fourteen diarylheptanoids: oregonin (1), platyphylloside (2), rubranoside A (3), rubranoside B (4), hirsutanonol (5), hirsutenone (6), hirsutanonol-5-O-β-D-glucopyranoside (7), platyphyllonol-5-O-β-D-xylopyranoside (8), aceroside...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1328301
更新日期:2013-04-01 00:00:00
abstract::Three pyrrolizidine alkaloids were isolated from Eupatorium portoricense and their structures elucidated by spectroscopic methods as (-)-viridifloryl-supinidine (amabiline), (-)-viridifloryl-heliotridine (echinatine), and C12- O-acetyl-(-)-viridifloryl-heliotridine (O(12)-acetylechinatine). ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-958112
更新日期:1995-08-01 00:00:00
abstract::The gamma-amino butyric acid (GABA) type A (GABA(A)) receptor represents a crucial target for clinical agents in the treatment of anxiety and insomnia. Using the two-microelectrode voltage clamp technique on recombinant α₁β₂γ(2S) GABA (A) receptors, effusol (1) and dehydroeffusol (2) were isolated in a bioactivity-gui...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0031-1298174
更新日期:2012-03-01 00:00:00
abstract::Praziquantel is the drug of choice for the treatment of schistosomiasis. However, several strains of Schistosoma mansoni are resistant to praziquantel, making it necessary to discover new drugs that might be used for its treatment. With this in mind, the properties of a schistosomicidal ethanolic extract of Garcinia b...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0035-1545927
更新日期:2015-06-01 00:00:00
abstract::In our previous study, we reported the interesting in vitro antiplasmodial activity of some Rwandan plant extracts. This gave rise to the need for these extracts to also be evaluated in vivo and to identify the compounds responsible for their antiplasmodial activity. The aim of our study was, on the one hand, to evalu...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0034-1368322
更新日期:2014-04-01 00:00:00
abstract::YANG XIN is a traditional Chinese medicine formulation used for nervous fatigue and consists of a proprietary blend of concentrated extracts from 18 plant ingredients. The 18 constituent plant ingredients, YANG XIN capsules, and formulations 2014-005_1 A and 1B were extracted by consecutive 24-hour macerations with di...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0042-106170
更新日期:2016-08-01 00:00:00
abstract::ECa 233, a standardized extract of Centella asiatica, has been found to exhibit various positive neurological effects and to have a good safety profile. The present study aimed to explore the disposition kinetics of ECa 233, containing madecassoside (53.1 %) and asiaticoside (32.3 %), in rats. The extract was intraven...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0042-122344
更新日期:2017-05-01 00:00:00