Biosynthesis of phenylalanine and tyrosine in claviceps.

Abstract:

:Some enzymes of the terminal steps of phenylalanine and tyrosine biosyntheses were investigated in various alkaloid-forming ergot strains. All strains studied utilize both arogenate and phenylpyruvate as an intermediate in L-phenylalanine synthesis. L-Tyrosine is preferentially or exclusively synthesized via the arogenate pathway. No feedback inhibition of arogenate pathway enzymes by aromatic amino acids was observed.

journal_name

Planta Med

journal_title

Planta medica

authors

Schmauder HP,Gröger D

doi

10.1055/s-2007-969195

subject

Has Abstract

pub_date

1986-10-01 00:00:00

pages

395-7

issue

5

eissn

0032-0943

issn

1439-0221

pub_type

杂志文章
  • Inhibition of lipid synthesis and secretion in long-term cultures of adult rat hepatocytes by alpha-asarone.

    abstract::In this work we studied the effect of alpha-asarone, a hypolipidemic active principle of Guatteria gaumeri Greenman, on hepatic lipid metabolism using adult rat hepatocytes cultured on a feeder layer of 3T3 cells. These cultures synthesize and secrete for at least two weeks various lipids from [14C]-acetic and [14C]-o...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-959625

    authors: Hernández A,López ML,Chamorro G,Mendoza-Figueroa T

    更新日期:1993-04-01 00:00:00

  • Polyacetylenic compounds and butanol fraction from Bidens pilosa can modulate the differentiation of helper T cells and prevent autoimmune diabetes in non-obese diabetic mice.

    abstract::Compelling evidence suggests that infiltrating CD4+ type I helper T (Th1) cells in the pancreatic islets play a pivotal role in the progression of diabetes in non-obese diabetic (NOD) mice. We demonstrate in the present report that a butanol fraction of B. pilosa suppressed the development of diabetes, helped maintain...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2004-832645

    authors: Chang SL,Chang CL,Chiang YM,Hsieh RH,Tzeng CR,Wu TK,Sytwu HK,Shyur LF,Yang WC

    更新日期:2004-11-01 00:00:00

  • New camptothecin and ellagic acid analogues from the root bark of Camptotheca acuminata.

    abstract::As part of a study on chemical constituents of Camptotheca species, one new natural camptothecin analogue (2), two new alkaloids (3, 4), one new ellagic acid analogue (5), and 19 known compounds (1, 6-23) have been isolated from the root bark, stem bark, fruits, and leaves of Camptotheca acuminata Decaisne. The struct...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2004-835854

    authors: Zhang Z,Li S,Zhang S,Liang C,Gorenstein D,Beasley RS

    更新日期:2004-12-01 00:00:00

  • Three new acylated glycosides from the stems of Casearia velutina and their protective effect against H2O2-induced impairment in PC12 cells.

    abstract::Chemical investigation of the stems of Casearia velutina led to the isolation and structural elucidation of three new acylated glycosides, casearicosides A-C (1-3), together with 13 known compounds. The structures of the new compounds were established by spectroscopic and chemical methods. These isolates were evaluate...

    journal_title:Planta medica

    pub_type: 信件

    doi:10.1055/s-0029-1185902

    authors: Chai XY,Li FF,Bai CC,Xu ZR,Shi HM,Tu PF

    更新日期:2010-01-01 00:00:00

  • Nematicidal activities of two phytoalexins from Taverniera abyssinica.

    abstract::The traditional analgesic and antipyretic Ethiopian drug "Dingetegna" is made of dried root material of Taverniera abyssinica A. Rich (Leguminosae). In a screening for nematicidal natural products, "Dingetegna" extracts showed strong nematicidal activities towards C. elegans. In the following, medicarpin and 4-hydroxy...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-959569

    authors: Stadler M,Dagne E,Anke H

    更新日期:1994-12-01 00:00:00

  • Equol but not genistein improves early metaphyseal fracture healing in osteoporotic rats.

    abstract::Healing of predominantly metaphyseal fractures in postmenopausal osteoporosis is delayed and comparatively poor. Hormone replacement therapy could improve fracture healing, but, because of its potential side effects, natural alternatives are more appealing. The aim of this study was to determine if the soy metabolite ...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0029-1185380

    authors: Kolios L,Sehmisch S,Daub F,Rack T,Tezval M,Stuermer KM,Stuermer EK

    更新日期:2009-04-01 00:00:00

  • Cytotoxic phenanthrenes from the rhizomes of Tamus communis.

    abstract::From the fresh rhizomes of Tamus communis five phenanthrenes (1 - 5) were isolated under the guidance of cytotoxic assays in HeLa cells. The compounds were obtained from the highly active CHCl (3) fraction of the MeOH extract by using multistep chromatographic purifications, including VLC, preparative TLC, HPLC and ge...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-941505

    authors: Réthy B,Kovács A,Zupkó I,Forgo P,Vasas A,Falkay G,Hohmann J

    更新日期:2006-06-01 00:00:00

  • Effects of genistein, an isoflavone isolated from Genista tridentata, on isolated guinea-pig ileum and guinea-pig ileal myenteric plexus.

    abstract::The inhibitory action of the major constituent of Genista tridentata L. (Papilionaceae), 4',5,7-trihydroxyisoflavone (genistein), on contractions induced by agonists and electrical field stimulation of smooth muscle was analysed. Genistein inhibited twitches evoked by electrical-stimulation of strips of guinea-pig ile...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-961474

    authors: Herrera MD,Marhuenda E,Gibson A

    更新日期:1992-08-01 00:00:00

  • Neolignan glycosides from Pedicularis longiflora.

    abstract::Four new neolignan glucosides, longiflorosides A, B, C and D, in addition to one known neolignan glucoside, dehydro-diconiferyl alcohol-4-O-beta-D-glucopyranoside were obtained from whole plants of Pedicularis longiflora. The structures of these compounds were determined mainly on spectral evidence. ...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-957662

    authors: Wang CZ,Jia ZJ

    更新日期:1997-06-01 00:00:00

  • Somatic embryogenesis and rhizogenesis of tissue cultures of two genotypes of Papaver somniferum: relationships to alkaloids production.

    abstract::PAPAVER SOMNIFERUM L. tissue cultures, issued from various explants (cotyledons, hypocotyls, roots) derived from plantlets belonging to two genotypes, were established on LS solid medium containing growth regulators (NAA, Kin) in various combinations. Hypocotyls and roots were found to be interesting explants to obtai...

    journal_title:Planta medica

    pub_type: 信件

    doi:10.1055/s-2006-960457

    authors: Laurain-Mattar D,Gillet-Manceau F,Buchon L,Nabha S,Fliniaux MA,Jacquin-Bubreuil A

    更新日期:1999-03-01 00:00:00

  • [Comparative study of two medicinal Cucurbitaceae].

    abstract::Comparative study of the seeds of two Cucurbitaceae Momordica charantia L. and Herpetospermum caudigerum Wall. shows and important difference for their metabolism concerning particularly aspartic acid. Momordica can produce vicin, while for Herpetospermum, this amino acid would give asparagin. In the other hand, betwe...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2007-971211

    authors: Barron D,Kaouadji M,Mariotte AM

    更新日期:1982-11-01 00:00:00

  • Prediction of the Passive Intestinal Absorption of Medicinal Plant Extract Constituents with the Parallel Artificial Membrane Permeability Assay (PAMPA).

    abstract::At the early drug discovery stage, the high-throughput parallel artificial membrane permeability assay is one of the most frequently used in vitro models to predict transcellular passive absorption. While thousands of new chemical entities have been screened with the parallel artificial membrane permeability assay, in...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0042-101247

    authors: Petit C,Bujard A,Skalicka-Woźniak K,Cretton S,Houriet J,Christen P,Carrupt PA,Wolfender JL

    更新日期:2016-03-01 00:00:00

  • Protective effect of Labisia pumila on stress-induced behavioral, biochemical, and immunological alterations.

    abstract::The aim of the present study was to investigate the antistress potential of LABISIA PUMILA aqueous extract (LPPM/A003) using a battery of tests widely employed in different stressful situations. Pretreatment of experimental animals with LPPM/A003 caused an increase in the swimming endurance and hypoxia time and also s...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0029-1240953

    authors: Kour K,Sharma N,Chandan BK,Koul S,Sangwan PL,Bani S

    更新日期:2010-10-01 00:00:00

  • Assessment of the anti-HIV activity of a pine cone isolate.

    abstract::Characterization of an alkali-soluble isolate from Pinus nigra Arnold (Pinaceae) seed cones by thioacidolysis revealed a significant phenylpropanoid (i.c. lignin) component which may provide the observed anti-HIV-1 activity for this substance. ...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-957801

    authors: Eberhardt TL,Young RA

    更新日期:1996-02-01 00:00:00

  • Absolute configuration of (6S,9S)-roseoside from Polygonum hydropiper.

    abstract::From Polygonum hydropiper L., a C13-norisoprenoid glucoside was isolated and its absolute configuration was established to be (6S,9S)-roseoside (1) by spectroscopic evidence and X-ray crystallographic analysis of its acetate derivative (2). In addition, the stereostructure of roseoside from Canthium subcordatum was re...

    journal_title:Planta medica

    pub_type: 信件

    doi:10.1055/s-2001-15812

    authors: Murai Y,Kashimura S,Tamezawa S,Hashimoto T,Takaoka S,Asakawa Y,Kiguchi K,Murai F,Tagawa M

    更新日期:2001-07-01 00:00:00

  • Possible active components of tan-shen (Salvia miltiorrhiza) for protection of the myocardium against ischemia-induced derangements.

    abstract::Extract of Tan-Shen (Salvia miltiorrhiza, Labiatae), a Chinese traditional crude drug, was reported to show beneficial activity for heart disease. Chemical examination on the extract was performed on the basis of screening for protective action on the ischemic myocardium. Isolated hearts were subjected to hypoxic perf...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-961824

    authors: Yagi A,Fujimoto K,Tanonaka K,Hirai K,Takeo S

    更新日期:1989-02-01 00:00:00

  • Allicin characterization and its determination by HPLC.

    abstract::Allicin has been synthesized and was purified by liquid chromatography. HPLC chromatograms recorded at different wavelengths reveal pure allicin at similar retention times. The purity of the allicin peak could be confirmed by diode array detection. Pure synthetic allicin has been identified by infrared and mass spectr...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-962811

    authors: Jansen H,Müller B,Knobloch K

    更新日期:1987-12-01 00:00:00

  • New aspects of DNA-based authentication of Chinese medicinal plants by molecular biological techniques.

    abstract::DNA technology provides a powerful tool to complement chemical analyses for authentication of Chinese medicinal plants and to ensure that herbal materials are not contaminated with ineffective or potentially harmful substitutes or adulterants. In the last two decades molecular biotechnology has provided sophisticated ...

    journal_title:Planta medica

    pub_type: 杂志文章,评审

    doi:10.1055/s-0030-1250519

    authors: Heubl G

    更新日期:2010-12-01 00:00:00

  • Effect of grafting on solasodine content in Solanum viarum.

    abstract::Solasodine--a steroid present in the mucilaginous exotesta of the seed in Solanum viarum Dunal (syn. S. khasianum var. chatterjeeanum) is a major source of steroidal raw material. Evidence for the site of solasodine synthesis was sought through reciprocal grafts involving steroid-bearing S. viarum (both diploid and au...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-957905

    authors: Srinivas M,Krishnan R

    更新日期:1996-08-01 00:00:00

  • Piper methysticum: enantiomeric separation of kavapyrones by high performance liquid chromatography.

    abstract::A simultaneous separation of the enantiomers of kawain, dihydrokawain, methysticin, and dihydromethysticin as well as the achiral dienolides yangonin and demethoxyyangonin was carried out on a ChiraSpher NT column. This HPLC method can be used for the investigation of the enantiomeric purity of plant material and herb...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-957606

    authors: Häberlein H,Boonen G,Beck MA

    更新日期:1997-02-01 00:00:00

  • Effect of long-term administration of cordycepin from Cordyceps militaris on testicular function in middle-aged rats.

    abstract::This study was carried out to examine the potential beneficial effect of cordycepin on the decline of testicular function induced with age. A total of 30 male Sprague-Dawley rats (twenty-four 12-month-olds and six 2-month-olds) were divided into five groups. The young control (YC) and middle-aged control (MC) groups r...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0032-1315212

    authors: Sohn SH,Lee SC,Hwang SY,Kim SW,Kim IW,Ye MB,Kim SK

    更新日期:2012-10-01 00:00:00

  • Two new secoiridoid glycosides from Gentiana algida.

    abstract::Two new acylated secoiridoid glycosides were isolated from the aqueous acetone extract of the whole herb of Gentiana algida. The structures of these new products were established by spectral and chemical methods as 6'-(2,3-dihydroxybenzoyl)sweroside and 6'-(2,3-dihydroxybenzoyl)swertiamarin, respectively. ...

    journal_title:Planta medica

    pub_type: 信件

    doi:10.1055/s-2006-957770

    authors: Tan RX,Hu J,Dong LD,Wolfender JL,Hostettmann K

    更新日期:1997-12-01 00:00:00

  • Evaluation of cytotoxic activity of Schisandra chinensis lignans.

    abstract::Using exhaustive chromatographic separation we have isolated (-)-tigloyl-deangeloyl-gomisin F as a novel dibenzocyclooctadiene lignan from schisandra chinensis. With the help of HPLC, we further isolated (+)-schisandrin, (+)-deoxyschisandrin, (+)-γ-schisandrin, (-)-gomisin J, (+)-gomisin A, (-)-gomisin N, (-)-tigloyl-...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0030-1249861

    authors: Smejkal K,Slapetová T,Krmenčík P,Babula P,Dall'Acqua S,Innocenti G,Vančo J,Casarin E,Carrara M,Kalvarová K,Dvorská M,Slanina J,Kramářová E,Julínek O,Urbanová M

    更新日期:2010-10-01 00:00:00

  • Antiherpetic activities of sulfated polysaccharides from green algae.

    abstract::In order to evaluate the potency of novel antiviral drugs, 11 natural sulfated polysaccharides (SPs) from 10 green algae ( Enteromorpha compressa, Monostroma nitidum, Caulerpa brachypus, C. okamurai, C. scapelliformis, Chaetomorpha crassa, C. spiralis, Codium adhaerens, C. fragille, and C. latum) and 4 synthetic sulfa...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2004-827228

    authors: Lee JB,Hayashi K,Maeda M,Hayashi T

    更新日期:2004-09-01 00:00:00

  • Telemetry as a tool to measure sedative effects of a valerian root extract and its single constituents in mice.

    abstract::Valeriana officinalis L. is a popular herbal treatment for mild sleep disorders. Clinical and non-clinical studies found contradictory results for valerian extracts and single constituents regarding the influence on sleep parameters. It was the aim of this study to investigate the sedative effects of a valerian root e...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0030-1250589

    authors: Chow NK,Fretz M,Hamburger M,Butterweck V

    更新日期:2011-05-01 00:00:00

  • A New Iridoid Glucoside of Swertia japonica.

    abstract::The structure of swertiaside, a new iridoid glucoside isolated from SWERTIA JAPONICA, was elucidated to be 7-epi-( M-hydroxybenzoyl)-loganicacid. ...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2007-969779

    authors: Ikeshiro Y,Tomita Y

    更新日期:1984-12-01 00:00:00

  • Vermistatin derivatives with α-glucosidase inhibitory activity from the mangrove endophytic fungus Penicillium sp. HN29-3B1.

    abstract::Three new vermistatin derivatives, 6-demethylpenisimplicissin (1), 5'-hydroxypenisimplicissin (2), and 2''-epihydroxydihydrovermistatin (3), along with five known vermistatin analogues, methoxyvermistatin (4), vermistatin (5), 6-demethylvermistatin (6), hydroxyvermistatin (7), and penisimplicissin (8), were isolated f...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0034-1382859

    authors: Liu Y,Xia G,Li H,Ma L,Ding B,Lu Y,He L,Xia X,She Z

    更新日期:2014-07-01 00:00:00

  • Structures of Crassicaulisine and Crassicaulidine, two New Diterpenoid Alkaloids.

    abstract::From the roots of Aconitum crassicaule, two new diterpenoid alkaloids, crassicaulisine and crassicaulidine, were isolated. The structure of crassicaulisine, C (24)H (39)O (7)N, has been elucidated as 3 on the basis of chemical and spectral data, while the structure of crassicaulidine, C (24)H (39)O (8)N, has been show...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2007-969945

    authors: Fengpeng W,Qicheng F

    更新日期:1983-01-01 00:00:00

  • Barbaloin in aloe species.

    abstract::Barbaloin levels in the exudates from the leaves of 68 species of ALOE in the Kew collection have been determined by light absorption at 375 nm following separation by HPLC. The exudates from most species contained between 10-20% although a few concentrations of around 30% were found. The level in the leaf was usually...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-962735

    authors: Groom QJ,Reynolds T

    更新日期:1987-08-01 00:00:00

  • Antiproliferative triterpenoid saponins from the stem of Psychotria sp.

    abstract::Six new triterpenoid saponins, psychotrianosides A-F (1-6), and two known triterpenoid saponins, psychotrianoside G (7) and ardisianoside D (8), were isolated from Psychotria sp. Their structures were determined mainly by spectroscopic methods. The cytotoxic activities of 1-8 against five human cancer cell lines (MDA-...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0032-1328650

    authors: Zhang CX,Zhang DM,Chen MF,Guan SY,Yao JH,He XX,Lei LF,Zhong Y,Wang ZF,Ye WC

    更新日期:2013-07-01 00:00:00