Flavonol glycoside gallate and ferulate esters from Persicaria lapathifolia as inhibitors of superoxide production in human monocytes stimulated by unopsonized zymosan.

Abstract:

:Aerial parts of Persicaria lapathifolia S.F. Gray (Polygonaceae) exhibited an inhibitory effect on superoxide production in unopsonized zymosan-stimulated human monocytes. Two known compounds, quercetin 3-O-beta-(2"-galloyl)-glucopyranoside and quercetin 3-O-beta-(2"-galloyl)-rhamnopyranoside, and a new compound, quercetin 3-O-beta-(6"-feruloyl)-galactopyranoside, were isolated as the inhibitors of superoxide production by activity-guided fractionation. IC50 values were shown at the concentrations of 2.1 microM by quercetin 3-O-beta-(2"-galloyl)-glucopyranoside, 1.9 microM by quercetin 3-O-beta-(2"-galloyl)-rhamnoypranoside, and 3.5 microM by quercetin 3-O-beta-(6"-feruloyl)-galactopyranoside whose inhibitory potencies were similar to oxyphenylbutazone (IC50 = 1.9 microM) as a positive control.

journal_name

Planta Med

journal_title

Planta medica

authors

Kim Y,Jang DS,Park SH,Yun J,Min BK,Min KR,Lee HK

doi

10.1055/s-0029-1243112

subject

Has Abstract

pub_date

2000-02-01 00:00:00

pages

72-4

issue

1

eissn

0032-0943

issn

1439-0221

journal_volume

66

pub_type

信件
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    abstract::Acetonylgeraniin, an active principle isolated from the seeds of Euphoria longana Lam. (Sapindaceae), reversed the fall in arterial blood pressure in conscious hypertensive rats (SHRs) with orthostatic hypotension induced by injection of hexamethonium into animals subjected to 90 degrees head-up tilts for 60 seconds. ...

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  • Effects of genistein on the mammary gland proliferation of adult ovariectomised Wistar rats.

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    authors: Hertrampf T,Schmidt S,Seibel J,Laudenbach-Leschowsky U,Degen GH,Diel P

    更新日期:2006-03-01 00:00:00

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  • Polyacetylenic compounds and butanol fraction from Bidens pilosa can modulate the differentiation of helper T cells and prevent autoimmune diabetes in non-obese diabetic mice.

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  • Protective Effects of Bacopa Monnieri on Hydrogen Peroxide and Staurosporine: Induced Damage of Human Neuroblastoma SH-SY5Y Cells.

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    doi:10.1055/s-2007-981542

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  • Dodonic Acid, A New Diterpenoid from Dodonaea viscosa1.

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    doi:10.1055/s-2007-969764

    authors: Sachdev K,Kulshreshtha DK

    更新日期:1984-10-01 00:00:00

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    abstract::Hot water extract (ALR-0) of rhizomes of Atractylodes lanceo DC. was fractionated into MeOH-soluble fraction (ALR-1), supernatant fraction of EtOH precipitation (ALR-3 + 4), and crude polysaccharide fraction (ALR-5). Among these fractions, only ALR-5 showed potent stimulating activity for proliferation of bone marrow ...

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    authors: Yu KW,Kiyohara H,Matsumoto T,Yang HC,Yamada H

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  • Bioavailability, pharmacokinetics, and tissue distribution of the oxypregnane steroidal glycoside P57AS3 (P57) from Hoodia gordonii in mouse model.

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  • [A comparative study of the effects of selection and environmental factors on alkaloid accumulation in strains of Choisya ternata].

    abstract::The accumulation of two dihydrofuroquinoline alkaloids has been studied in seventeen strains of Choisya ternata (Rutaceae) initiated from the same tree. The contents of platydesminium and balfourodinium vary in heavy proportions. The effect of some factors (age of the culture, NAA or glucose concentrations of the medi...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2007-971221

    authors: Gras M,Crèche J,Chénieux JC,Rideau M

    更新日期:1982-12-01 00:00:00

  • Assay of volatile oil-cyclodextrin complexes by pyrolyzis gas-chromatography.

    abstract::A pyrolytic gaschromatographic process was developed for the routine assay of both cyclodextrin inclusion complexes, and for the differentiation of the mechanical mixture of the same oil with beta-cyclodextrin. The method is a direct assay of low material demand. ...

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    doi:10.1055/s-2007-971636

    authors: Pobozsny K,Kernóczi L,Tétényi P,Héthelyi I,Szejtli J

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  • Flow Cytometric Analysis of Cellular Berberine Contents in High- and Low-Producing Cell Lines of Coptis japonica Obtained by Repeated Selection.

    abstract::Cell lines that were highly productive for berberine were selected by repeated cloning of small cell aggregates. The berberine content of the highest-producing cell line increased after 4 clonings to 10% dw in comparison to the 3% dw found for the parent line, and the berberine yield was about 1,500 mg/1/14 days. Ther...

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    doi:10.1055/s-2006-961910

    authors: Hara Y,Yamagata H,Morimoto T,Hiratsuka J,Yoshioka T,Fujita Y,Yamada Y

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  • Evaluation of the anti-trypanosomal activity of tyropeptin A.

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    pub_type: 杂志文章

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    更新日期:1986-08-01 00:00:00

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    pub_type: 杂志文章,评审

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  • Flavonoids and a sesquiterpene lactone from Tanacetum microphyllum inhibit anti-inflammatory mediators in LPS-stimulated mouse peritoneal macrophages.

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    pub_type: 杂志文章

    doi:10.1055/s-2004-815452

    authors: Abad MJ,Bermejo P,Alvarez M,Guerra JA,Silván AM,Villar AM

    更新日期:2004-01-01 00:00:00

  • New Tirucallane-Type Triterpenoids from Guarea guidonia.

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    pub_type: 杂志文章

    doi:10.1055/s-0044-100524

    authors: Hernandez V,De Leo M,Cotugno R,Braca A,De Tommasi N,Severino L

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    pub_type: 杂志文章

    doi:10.1055/s-0031-1298432

    authors: Wang YH,Avula B,Fu X,Wang M,Khan IA

    更新日期:2012-05-01 00:00:00

  • Aromatase inhibitory activities of standishinal and the diterpenoids from the bark of Thuja standishii.

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    pub_type: 杂志文章

    doi:10.1055/s-2002-33787

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    更新日期:2002-08-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1055/s-2007-969610

    authors: Richomme P,Lavault M,Jacquemin H,Bruneton J

    更新日期:1984-02-01 00:00:00

  • [Plants from new caledonia: alkaloids of stem-bark of Hernandia cordigera].

    abstract::The alkaloidal content of of the stem barks of Hernandia cordigera has been studied and compared to that of other Hernandia species. Main alkaloids are phenolic aporphines. ...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2007-971545

    authors: Lavault M,Debray MM,Bruneton J

    更新日期:1981-05-01 00:00:00