Flavonol glycoside gallate and ferulate esters from Persicaria lapathifolia as inhibitors of superoxide production in human monocytes stimulated by unopsonized zymosan.

abstract：:Besides the known pyrrolidine alkaloids ruspolinone ( 1), norruspolinone ( 2), and norruspoline ( 3) the "bispyrrolidine" alkaloid hypercratine was isolated from the roots of RUSPOLIA HYPERCRATERIFORMIS M. R. (Acanthaceae). After chemical and spectroscopic analysis of the new compound, structure 4 is suggested. ...

journal_title：Planta medica

authors： Neukomm G,Roessler F,Johne S,Hesse M

更新日期：1983-08-01 00:00:00

abstract：:Two new lignans, (-)-aptosimon ( 1) and (-)-diasesamin-di-gamma-lactone ( 2), together with twenty-two known compounds, have been isolated from the stems and roots of Wikstroemia lanceolata. The structures of the new compounds were determined through spectral analyses. The proton and carbon assignments of the known se...

journal_title：Planta medica

authors： Lin RW,Tsai IL,Duh CY,Lee KH,Chen IS

更新日期：2004-03-01 00:00:00

abstract：:From the fresh, undried, and uncrushed leaves of NERIUM OLEANDER a new triterpenoid, kanerocin, has been isolated along with known ursolic and oleanolic acids and its structure established through chemical and spectroscopic methods as 3alpha-hydroxy-urs-18,20-dien-28-oic acid. ...

journal_title：Planta medica

authors： Siddiqui S,Siddiqui BS,Begum S,Hafeez F

更新日期：1989-06-01 00:00:00

abstract：:The immunomodulatory activity of HN-02, an extract containing a mixture of andrographolides (i.e., andrographolide [88 +/- 5 %] plus 14-deoxyandrographolide and 14-deoxy-11,12-didehydroandrographolide together [12 +/- 3 %]) in a pure powder form was evaluated at 1.0, 1.5, and 2.5 mg/kg on different in vivo and in vitr...

journal_title：Planta medica

authors： Naik SR,Hule A

更新日期：2009-06-01 00:00:00

abstract：:Eight compounds were isolated from the CH (2)Cl (2) extracts of ERYTHRINA SENEGALENSIS to assess HIV-1 protease (PR) activity inhibition. The prenylated isoflavone structures, identified by spectroscopic analysis, were 8-prenylluteone ( 1), auriculatin ( 2), erysenegalensein O ( 3), erysenegalensein D ( 4), erysenegal...

journal_title：Planta medica

authors： Lee J,Oh WK,Ahn JS,Kim YH,Mbafor JT,Wandji J,Fomum ZT

更新日期：2009-02-01 00:00:00

abstract：:Callus induction starting from the rhizome tissue of plants of three CURCUMA species: CURCUMA ZEDOARIA Roscoe, C. DOMESTICA Valeton, and C. AROMATICA Salisbury (Zingiberaceae) was performed. Successful callus formation was obtained in all three species using Murashige-Skoog's (MS) medium supplemented with 1-naphthalen...

journal_title：Planta medica

authors： Yasuda K,Tsuda T,Shimizu H,Sugaya A

更新日期：1988-02-01 00:00:00

abstract：:One new diterpene, 2 alpha-hydroxy-12beta-hydroxy-isopimara-8(14), 15-diene, and six known compounds as triterpenes, sterols and fatty acid, were isolated from the stem bark of Tanaecium jaroba (Bignoniaceae), a Bolivian plant used in traditional medicine. Their structures were established mainly by 1D and 2D NMR (COS...

journal_title：Planta medica

authors： Mitaine-Offer AC,Sauvain M,Deharo E,Muñoz V,Zèches-Hanrot M

更新日期：2002-06-01 00:00:00

abstract：:The hypoglycaemic effect of orally administered extracts of leaves and roots of Coccinia indica has been reported earlier. The oral administration of the pectin isolated from the fruit of the above plant at a dose of 200 mg/100 g BW/day showed a significant hypoglycaemic action in normal rats. Pectins isolated from ma...

journal_title：Planta medica

authors： Kumar GP,Sudheesh S,Vijayalakshmi NR

更新日期：1993-08-01 00:00:00

abstract：:The pharmacokinetic profile of arctiin, the major active lignan in fruits of Arctium lappa L., was investigated. Its main meta"bolite arctigenin was identified by an LC-MS method, and an HPLC-UV technique was developed for the simultaneous quantification of the metabolite and arctiin in plasma and organs. Chromatograp...

journal_title：Planta medica

authors： He F,Dou DQ,Sun Y,Zhu L,Xiao HB,Kang TG

更新日期：2012-05-01 00:00:00

abstract：:Sesquiterpene lactones 1-5 were isolated for the first time from the ethyl acetate of Vernonia fastigiata (Asteraceae). Compounds 3, 4 and 5 are new, compounds 1 and 2 have been found earlier in other Vernonia species but not in V. fastigiata. ...

journal_title：Planta medica

authors： Roos G,Prawat H,Walter CU,Klaiber I,Vogler B,Guse JH,Kraus W

更新日期：1998-10-01 00:00:00

abstract：:Twelve phenolic compounds, including three stilbenes, two flavonoids, two coumarins, one neolignan, and four lignans, isolated from Euphorbia and Pycnanthus species or obtained by derivatization, were assayed for their potential antineoplastic efficacy in three human cancer cell lines: gastric (EPG85-257), pancreatic ...

journal_title：Planta medica

authors： Duarte N,Lage H,Abrantes M,Ferreira MJ

更新日期：2010-07-01 00:00:00

abstract：:Many herbs, and recently their biomass from in vitro cultures, are essential for the treatment of diseases. The aim of this study was to determine the optimal growth of Bacopa monnieri (water hyssop) in an in vitro culture and to examine if extracts of the B. monnieri biomass from the in vitro culture would affect hyd...

journal_title：Planta medica

authors： Łojewski M,Pomierny B,Muszyńska B,Krzyżanowska W,Budziszewska B,Szewczyk A

更新日期：2016-02-01 00:00:00

abstract：:According to traditional usage, the extract of Longan Arillus was tested for its anxiolytic-like effect by application of the Vogel-type anti-conflict method in mice. The extract indicated significant activity at a dose of 2 g/kg, s.c., and results of the bioassay-oriented isolation revealed adenosine to be the active...

journal_title：Planta medica

authors： Okuyama E,Ebihara H,Takeuchi H,Yamazaki M

更新日期：1999-03-01 00:00:00

abstract：:Two new lactones, 1 and 2, together with five known compounds, 3-7, were isolated from the marine mangrove fungus Xylaria sp. BL321. Their structures were determined by comprehensive analysis of their MS and NMR spectroscopic data. The absolute configurations of 1 and 2 were established on the basis of electronic circ...

journal_title：Planta medica

authors： Song YX,Wang J,Li SW,Cheng B,Li L,Chen B,Liu L,Lin YC,Gu YC

更新日期：2012-01-01 00:00:00

abstract：:Teak ( Tectona grandis L.f., Verbenaceae) sawdust extract inhibited the growth of Aspergillus niger. Centrifugal partition chromatography was used to isolate the active compounds. By (1)H-NMR the active compounds were identified as deoxylapachol and tectoquinone. Two A. niger transgenic strains which show induction of...

journal_title：Planta medica

authors： Sumthong P,Damveld RA,Choi YH,Arentshorst M,Ram AF,van den Hondel CA,Verpoorte R

更新日期：2006-08-01 00:00:00

abstract：:The fruits of OSTEOPHLOEUM PLATYSPERMUM (Myristicaceae) contain sitosterol, eperu-8(20),13-dien-3alpha,15-diol, glyceryl laurodimyristate, glyceryl 1,3-lauromyristate and five neolignans: dihydroguaiaretic acid, hydroxyotobain, hydroxyoxootobain, guaiacin and otobaphenol. ...

journal_title：Planta medica

authors： Fo RB,de Carvalho MG,Gottlieb OR

更新日期：1984-02-01 00:00:00

abstract：:Protodioscin (NSC-698 796) is a furostanol saponin isolated from the rhizome of Dioscorea collettii var. hypoglauca (Dioscoreaceae), a Chinese herbal remedy for the treatment of cervical carcinoma, carcinoma of urinary bladder and renal tumor for centuries. To systematically evaluate its potential anticancer activity,...

journal_title：Planta medica

authors： Hu K,Yao X

更新日期：2002-04-01 00:00:00

abstract：:This perspective describes some commonly used animal models for the evaluation of potential chemopreventive agents in colon carcinogenesis. Special emphasis is given to the azoxymethane (AOM)/1,2-dimethylhydrazine (DMH) rat model and APCMIN mice, carrying a mutation in APC, a key gene in human carcinogenesis. In the A...

journal_title：Planta medica

authors： Femia AP,Caderni G

更新日期：2008-10-01 00:00:00

abstract：:Transformed root cultures of ipecac (Cephaelis ipecacuanha A. Richard), one of the recalcitrant woody plant species for Agrobacterium-mediated transformation, were established by co-culturing of in vitro petiole segments with Agrobacterium rhizogenes ATCC 15 834. Southern blot analysis of the established roots reveale...

journal_title：Planta medica

authors： Yoshimatsu K,Shimomura K,Yamazaki M,Saito K,Kiuchi F

更新日期：2003-11-01 00:00:00

abstract：:Embelia ribes Burm. f. (Myrsinaceae) is one of the important plants used in Indian traditional medicine. RAPD-PCR analysis was performed to obtain species-specific DNA fragments. A band of 906 bp that was specific to Embelia ribes irrespective of the geographical source was obtained using the random decamer primer OPF...

journal_title：Planta medica

authors： Devaiah KM,Venkatasubramanian P

更新日期：2008-02-01 00:00:00

abstract：:Aerial parts of Pterocaulon polystachyum from Chaco province, Argentina, afforded the known coumarins ayapin, isoscopoletin, prenyletin, prenyletin methyl ether, virgatenol, obtusinin, 5-methoxy-6,7-methylenedioxycoumarin, 5-(3,3-dimethylallyloxy)-6,7-methylenedioxycoumarin, 5-(2',3'-dihydroxy-3-methylbutanoxy)-6,7-me...

journal_title：Planta medica

authors： Vera N,Bardón A,Catalán CA,Gedris TE,Herz W

更新日期：2001-10-01 00:00:00

abstract：:Phytoestrogens are discussed as candidate substances to treat symptoms related to estrogen deficiency. In in vitro experiments, the naturally occurring flavonoid 6-(1,1-dimethylallyl)naringenin (6-DMAN) emerged as one of the most potent phytoestrogenic substances. 6-DMAN is not as well characterized as other flavonoid...

journal_title：Planta medica

authors： Zierau O,Geis RB,Tischer S,Schwab P,Metz P,Vollmer G

更新日期：2004-07-01 00:00:00

abstract：:Enzymatic thrombin activity is significantly inhibited only by a few selected natural phenolic compounds (myricetin, rosmarinic acid, caffeic acid phenethyl ester) but more strongly by unsaturated fatty acids like erucic acid and oleic acids. Compared to the inhibitory potential against neutrophil elastase, thrombin a...

journal_title：Planta medica

authors： Melzig MF,Henke K

更新日期：2005-08-01 00:00:00

abstract：:Ginsenosides are the major principles of Panax ginseng C. A. Meyer (Araliaceae) used as a mild oriental folk medicine. In this report, we have examined the inhibitory potency of protopanaxadiol ginsenosides (PPDGs) such as Rb1, Rb2 and Rc, and their co-treatment effect with known tumor necrosis factor (TNF)-alpha anta...

journal_title：Planta medica

authors： Cho JY,Yoo ES,Baik KU,Park MH,Han BH

更新日期：2001-04-01 00:00:00

abstract：:The pharmacokinetics of huperzine A in dogs after single intravenous and oral administrations was investigated. Concentrations of huperzine A were determined by a validated liquid chromatography-tandem mass spectrometry (LC-MS/MS) method. Pharmacokinetic parameters were calculated by non-compartmental methods. After s...

journal_title：Planta medica

authors： Chu D,Liu W,Li Y,Li P,Gu J,Liu K

更新日期：2006-05-01 00:00:00

abstract：:Chemical investigation of the EtOH extract of Morus alba L. (Moraceae), as guided by free radical scavenging activity, furnished 5,7-dihydroxycoumarin 7-methyl ether (1), two prenylflavones, cudraflavone B (2) and cudraflavone C (3), and oxyresveratrol (4). Compounds 1 and 4 showed superoxide scavenging effects with t...

journal_title：Planta medica

authors： Oh H,Ko EK,Jun JY,Oh MH,Park SU,Kang KH,Lee HS,Kim YC

更新日期：2002-10-01 00:00:00

abstract：:Tuberculosis, also called TB, is currently a major health hazard due to multidrug-resistant forms of bacilli. Global efforts are underway to eradicate TB using new drugs with new modes of action, higher activity, and fewer side effects in combination with vaccines. For this reason, unexplored new sources and previousl...

journal_title：Planta medica

authors： Santhosh RS,Suriyanarayanan B

更新日期：2014-01-01 00:00:00

abstract：:Andrographolide (Andro) is a potentially anti-inflammatory diterpenoid lactone isolated from the traditional herbal medicine ANDROGRAPHIS PANICULATA, which has been effectively used for the treatment of infection, inflammation, cold, fever and diarrhea in China for centuries. In the current study, we found that Andro ...

journal_title：Planta medica

authors： Ji L,Liu T,Liu J,Chen Y,Wang Z

更新日期：2007-10-01 00:00:00

abstract：:Nano-encapsulation of several natural products has become an important tool in enhancing the bioavailability of some modern drugs against many diseases. Pelargonidin is an anthocyanidin found in many fruits and vegetables. Pelargonidin is loaded with poly-lactide-co-glycolic-acid, a non-toxic biodegradable polymer, to...

journal_title：Planta medica

authors： Samadder A,Tarafdar D,Abraham SK,Ghosh K,Khuda-Bukhsh AR

更新日期：2017-03-01 00:00:00

abstract：:Sungucine and isosungucine are two bisindole alkaloids isolated from the roots of the African plant Strychnos icaja Baillon. They both exhibit antiplasmodial activities but also show cytotoxic effects against human cancer cell lines. In order to elucidate their mechanism of action, we have investigated the interaction...

journal_title：Planta medica

authors： Lansiaux A,Bailly C,Houssier C,Colson P,De Pauw-Gillet MC,Frédérich M,Tits M,Angenot L

更新日期：2002-07-01 00:00:00