Plasma pharmacokinetics and tissue distribution of arctiin and its main metabolite in rats by HPLC-UV and LC-MS.

abstract：:The seed pods of Erythrina latissima yielded erysotrine, erysodine, syringaresinol, vanillic acid, a new erythrina alkaloid, (+)-10,11-dioxoerysotrine, which was lethal to brine shrimp and 2-(5'-hydroxy-3'-methoxy phenyl)-6-hydroxy-5-methoxybenzofuran, which showed strong antimicrobial activity against the yeast spore...

journal_title：Planta medica

authors： Wanjala CC,Juma BF,Bojase G,Gashe BA,Majinda RR

更新日期：2002-07-01 00:00:00

abstract：:Seven new compounds, including four lignans, (+)-(8S,8′S)-9,9′-dibenzoylsecoisolariciresinol (1), (+)-(8S*,8′R*)-4,4′-dimethyloxomatairesinol (2), (+)-(7S*,8R*,8′R*,9′S*)-9′-n-butoxytsugacetal (3), and pseudolarkaemin A (4), a pyronane glycoside, pseudolarkaemin B (5), an ent-beyerene glycoside, pseudolarkaemin C (6),...

journal_title：Planta medica

authors： He WJ,Chu HB,Zhang YM,Han HJ,Yan H,Zeng GZ,Fu ZH,Olubanke O,Tan NH

更新日期：2011-11-01 00:00:00

abstract：:In natural product chemistry, it is often crucial to determine sugar composition as well as the absolute configuration of each monosaccharide in glycosides. An ultra-performance liquid chromatography method using both photodiode array (PDA) and mass spectrometry detectors (UPLC-UV/MS) was developed for qualitative ana...

journal_title：Planta medica

authors： Wang YH,Avula B,Fu X,Wang M,Khan IA

更新日期：2012-05-01 00:00:00

abstract：:Chemical investigation of the EtOH extract of Morus alba L. (Moraceae), as guided by free radical scavenging activity, furnished 5,7-dihydroxycoumarin 7-methyl ether (1), two prenylflavones, cudraflavone B (2) and cudraflavone C (3), and oxyresveratrol (4). Compounds 1 and 4 showed superoxide scavenging effects with t...

journal_title：Planta medica

authors： Oh H,Ko EK,Jun JY,Oh MH,Park SU,Kang KH,Lee HS,Kim YC

更新日期：2002-10-01 00:00:00

abstract：:Mulberroside A, a major stilbene constituent of MORUS ALBA L. (Moraceae), displays significant antitussive and antiasthmatic effects in animals. As part of our ongoing research on its biotransformation in rats, mulberroside A was orally administered to rats, and the metabolites in the gastrointestinal contents and fec...

journal_title：Planta medica

authors： Zhaxi M,Chen L,Li X,Komatsu K,Yao X,Qiu F

更新日期：2010-03-01 00:00:00

abstract：:Thirty-five flavonoids of seven different types, namely isoflavonoids, chalcones, dihydroflavonols, flavanols, flavanones, flavones, and flavonols were investigated for their ability to inhibit ascorbate-induced microsomal lipid peroxidation and their cytotoxicity. For each activity a structure-activity relationship w...

journal_title：Planta medica

authors： Cos P,Calomme M,Sindambiwe JB,De Bruyne T,Cimanga K,Pieters L,Vlietinck AJ,Vanden Berghe D

更新日期：2001-08-01 00:00:00

abstract：:The new I-3', II-3, 3', II-4', I-5, II-5, I-7, II-7-octahydroxy-I-4'-methoxy-I-3, II-8-biflavanone together with known biflavanones GB-1 and GB-2 were isolated from the bark of GARCINIA KOLA. ...

journal_title：Planta medica

authors： Kabangu K,Galeffi C,Aonzo E,Nicoletti M,Messana I

更新日期：1987-06-01 00:00:00

abstract：:Turmeric has been extensively utilized in Indian and Chinese medicine for its immune-modulatory properties. Dendritic cells (DCs) are antigen-presenting cells specialized to initiate and regulate immunity. The ability of DCs to initiate immunity is linked to their activation status. The effects of turmeric on human DC...

journal_title：Planta medica

authors： Krasovsky J,Chang DH,Deng G,Yeung S,Lee M,Leung PC,Cunningham-Rundles S,Cassileth B,Dhodapkar MV

更新日期：2009-03-01 00:00:00

abstract：:Three new pyrone glucosidic derivatives, together with the known pyromeconic acid glucoside, three acytelenes and two eudesmanes, were obtained from the aerial parts of Conyza albida. The structures were elucidated by high field NMR spectroscopy. ...

journal_title：Planta medica

authors： Ahmed AA,Mohamed Ael-H,Tzakou O,Gani A,Yannitsaros A,El-Maghraby MA,Hassan ME,Zeller KP

更新日期：2002-07-01 00:00:00

abstract：:The new diterpenoids, candesalvoquinone, 12- O-methylcandesalvone B, candesalvone B methyl ester with the 3,4-secoabietane skeleton, and candelabroquinone with the abietane skeleton were isolated from the aerial parts of Salvia candelabrum, together with the known compound candelabrone. The structures were established...

journal_title：Planta medica

authors： Hohmann J,Janicsák G,Forgo P,Rédei D,Máthé I,Bartók T

更新日期：2003-03-01 00:00:00

abstract：:Bioactivity-guided fractionation of Saururus chinensis (Saururaceae) using a lymphoproliferation assay led us to isolate 5 lignans (compounds 1 - 5). Compounds 1 - 5 were identified as sauchinone, (-)-saucerneol, saucerneol C, manassantin A, and manassantin B, respectively, by spectroscopic analyses. The immunosuppres...

journal_title：Planta medica

authors： Park SY,Lee SH,Choi WH,Koh EM,Seo JH,Ryu SY,Kim YS,Kwon DY,Koh WS

更新日期：2007-06-01 00:00:00

abstract：:The specific physiological responses induced by inhaling R-(-)- as well as S-(+)-linalool in 24 human subjects undergoing experimental stress were investigated in this study. Various physiological parameters of the autonomous nervous system (heart rate, blood pressure, electrodermal activity) as well as the endocrine ...

journal_title：Planta medica

authors： Höferl M,Krist S,Buchbauer G

更新日期：2006-10-01 00:00:00

abstract：:This paper reports the phytochemical investigation of the 50% aq. EtOH extract of Houttuynia cordata, an effective TCM and functional food in China, which led to the isolation of 17 flavonoids including four new ones. The four new compounds were flavonoid derivatives tethered with houttuynin (3-oxododecanal). Each of ...

journal_title：Planta medica

authors： Chen SD,Li T,Gao H,Zhu QC,Lu CJ,Wu HL,Peng T,Yao XS

更新日期：2013-12-01 00:00:00

abstract：:A new isoprenylated xanthone, cudrafrutixanthone A, was isolated from the roots of Cudrania fruticosa, together with 18 known compounds. Their structures were elucidated by spectroscopic methods. Most isoprenylated xanthones exhibited cytotoxicity against HCT-116, SMMC-7721, SGC-7901, and BGC-823 cell lines with IC (5...

journal_title：Planta medica

authors： Wang YH,Hou AJ,Zhu GF,Chen DF,Sun HD

更新日期：2005-03-01 00:00:00

abstract：:The inhibition of aflatoxin B1 (AFB1) metabolism by a water extract of the root of Scutellaria baicalensis and its flavonoids was examined in liver microsomes. AFB1 is known to be metabolized to aflatoxin M1 (AFM1), aflatoxin Q1 (AFQ1), and AFB1-8,9-epoxide (AFBO). The water extract potently inhibited the production o...

journal_title：Planta medica

authors： Kim BR,Kim DH,Park R,Kwon KB,Ryu DG,Kim YC,Kim NY,Jeong S,Kang BK,Kim KS

更新日期：2001-07-01 00:00:00

abstract：:Bioassay directed fractionation of the (1:1) chloroform-methanol extract of Gentiana spathacea H.B.K (Gentianaceae) led to the isolation of gentiopicroside (gentiopricrin) (1), the major spasmolytic component of the plant. Gentiopicroside inhibited, in a concentration-dependent manner, the spontaneous contractions of ...

journal_title：Planta medica

authors： Rojas A,Bah M,Rojas JI,Gutiérrez DM

更新日期：2000-12-01 00:00:00

abstract：:A new isoquinoline alkaloid (6), along with nine known ones (1-5, 7-10), was isolated from the plateau plant Corydalis hendersonii, which is used as a traditional Tibetan medicine. The structure of the new compound was elucidated as 9-methyldecumbenine C by spectroscopic evidence. ...

journal_title：Planta medica

authors： Fu Y,Zhou Y,Liao X,Bai B,Peng S,Ding L

更新日期：2009-04-01 00:00:00

abstract：:Two new coumaryloxy triterpenoids, neriucoumaric and isoneriucoumaric acids, have been isolated from fresh, undried and uncrushed leaves of NERIUM OLEANDER and their structures established as 3beta-hydroxy-2alpha-cis- P-coumaryloxy-urs-12-en-28-oic acid and 3beta-hydroxy-2alpha- TRANS- P-coumaryloxy-urs-12-en-28-oic a...

journal_title：Planta medica

authors： Siddiqui S,Siddiqui BS,Hafeez F,Begum S

更新日期：1987-10-01 00:00:00

abstract：:Cissampentine A (1), an enantiomer of cissampentin, three new cycleatjehenine-type bisbenzylisoquinoline alkaloids, cissampentine B-D (2-4), and five known alkaloids were isolated from the roots of Cyclea tonkinensis. Their structures were established by interpretation of NMR, high-resolution ESI-MS data, and CD spect...

journal_title：Planta medica

authors： Wang JZ,Liao J,Xu WL,Chen XB

更新日期：2015-05-01 00:00:00

abstract：:Chemical studies on the constituents from the dragon's blood of Dracaena cambodiana led to the discovery of three new flavonoid derivatives (1- 3) and six known compounds (4- 9). The structures of the three new compounds were elucidated by NMR and MS spectroscopic analyses. All compounds were evaluated for their growt...

journal_title：Planta medica

authors： Luo Y,Wang H,Zhao YX,Zeng YB,Shen HY,Dai HF,Mei WL

更新日期：2011-12-01 00:00:00

abstract：:Evodiamine, a major alkaloidal principle of Evodia fruits (Evodia rutaecarpa, Rutaceae), showed vanilloid receptor agonistic activities comparable to capsaicin. The Chinese literature refers to Evodia fruits as a "hot nature" herb. In spite of the similarities in the actions of evodiamine and capsaicin in vitro, evodi...

journal_title：Planta medica

authors： Kobayashi Y,Nakano Y,Kizaki M,Hoshikuma K,Yokoo Y,Kamiya T

更新日期：2001-10-01 00:00:00

abstract：:Raspberry ketone (RK) is a natural phenolic compound of the red raspberry. The dietary administration of RK to male mice has been reported to prevent high-fat diet-induced elevation in body weight and to increase lipolysis in white adipocytes. To elucidate a possible mechanism for the antiobesity action of RK, its eff...

journal_title：Planta medica

authors： Park KS

更新日期：2010-10-01 00:00:00

abstract：:The aim of this study was to evaluate the effects of 7-epiclusianone (7-epi) on specific virulence attributes of Streptococcus mutans in vitro and on development of dental caries in vivo. 7-Epi was obtained and purified from fruits of Rheedia brasiliensis. We investigated its influence on surface-adsorbed glucosyltran...

journal_title：Planta medica

authors： Branco-de-Almeida LS,Murata RM,Franco EM,dos Santos MH,de Alencar SM,Koo H,Rosalen PL

更新日期：2011-01-01 00:00:00

abstract：:Stabilization of growth factors in a wound environment is critical to the wound healing process. Here we report on the stabilization of key growth factors by a unique plant cell wall biomaterial. MicroSheets are clear cell wall fragments isolated from the non-living water storage cells in the pulp or inner gel of Aloe...

journal_title：Planta medica

authors： Ni Y,Turner D,Yates K,Tizard I

更新日期：2007-10-01 00:00:00

abstract：:The quantification of free and total alkannins in 13 endemic Anatolian Alkanna species is described for the first time. Extraction of the samples was performed by sonication with hexane, followed by hydrolysis in 1 N NaOH. For analysis, a new HPLC method, utilizing reversed phase material (Synergi Max RP), was develop...

journal_title：Planta medica

authors： Pekin G,Ganzera M,Senol S,Bedir E,Korkmaz KS,Stuppner H

更新日期：2007-03-01 00:00:00

abstract：:Two new acylated secoiridoid glycosides were isolated from the aqueous acetone extract of the whole herb of Gentiana algida. The structures of these new products were established by spectral and chemical methods as 6'-(2,3-dihydroxybenzoyl)sweroside and 6'-(2,3-dihydroxybenzoyl)swertiamarin, respectively. ...

journal_title：Planta medica

authors： Tan RX,Hu J,Dong LD,Wolfender JL,Hostettmann K

更新日期：1997-12-01 00:00:00

abstract：:A new BIS-1-oxaquinolizidine alkaloid, 9'- EPI-3 β,3' β-dimethylxestospongin C (2), and three known related analogues have been isolated from the Hainan sponge Neopetrosia exigua. ...

journal_title：Planta medica

authors： Li Y,Qin S,Guo YW,Gu YC,van Soest RW

更新日期：2011-01-01 00:00:00

abstract：:The effects of the essential oil of Mentha pulegium L. (EOMP), a plant commonly known as "pennyroyal" or "poejo" that is used in folk medicine as an abortifaceant, were assessed on the isolated rat myometrium. Myometrial strips were stimulated with 10 nM oxytocin or 10 microM PGF (2alpha). EOMP (10 - 300 microg/mL) co...

journal_title：Planta medica

authors： Soares PM,Assreuy AM,Souza EP,Lima RF,Silva TO,Fontenele SR,Criddle DN

更新日期：2005-03-01 00:00:00

abstract：:Two new naphtho-pyrone glycosides, 9-[(beta-D-glucopyranosyl-(1----6)-O-beta-D-glucopyranosyl)oxy]-10- hydroxy-7-methoxy-3-methyl-1H-naphtho[2,3-c]pyran-1 -one (5) and 6-[(alpha-apiofuranosyl-(1----6)-O-beta-D-glucopyranosyl)oxy]- rubrofusarin (6), together with cassiaside (3) and rubrofusarin-6-beta-gentiobioside (4)...

journal_title：Planta medica

authors： Wong SM,Wong MM,Seligmann O,Wagner H

更新日期：1989-06-01 00:00:00

abstract：:Praziquantel is the drug of choice for the treatment of schistosomiasis. However, several strains of Schistosoma mansoni are resistant to praziquantel, making it necessary to discover new drugs that might be used for its treatment. With this in mind, the properties of a schistosomicidal ethanolic extract of Garcinia b...

journal_title：Planta medica

authors： Castro AP,de Mattos AC,Pereira NA,Anchieta NF,Silva MS,Dias DF,Silva CA,Barros GV,Souza RL,Dos Santos MH,Marques MJ

更新日期：2015-06-01 00:00:00