9'-Epi-3β,3'β-dimethylxestospongin C, a new macrocyclic diamine alkaloid from the Hainan sponge Neopetrosia exigua.

abstract：:A museum collection of Cinchonae cortex samples (n = 117), from the period 1850-1950, was extracted with a mixture of chloroform-d1, methanol-d4, water-d2, and perchloric acid in the ratios 5 : 5 : 1 : 1. The extracts were directly analyzed using 1H NMR spectroscopy (600 MHz) and the spectra evaluated using principal ...

journal_title：Planta medica

authors： Yilmaz A,Nyberg NT,Jaroszewski JW

更新日期：2012-11-01 00:00:00

abstract：:Shoot-tips from several genotypes of the cardenolide-producing perennial shrub Digitalis obscura L. were successfully cryopreserved using the encapsulation-dehydration technique. Precultivation on MS medium containing 0.5 M sucrose, followed by 2.5 h dehydration (final weight 30 %) induced shoot regrowth in 42 % of cr...

journal_title：Planta medica

authors： Sales E,Nebauer SG,Arrillaga I,Segura J

更新日期：2001-12-01 00:00:00

abstract：:The fruit of Ziziphus jujuba Mill., known as jujube or Chinese date, is commonly consumed as health supplement or herbal medicine worldwide. To study the beneficial role of jujube in enhancing hematopoietic function, we investigated its roles on the expression of erythropoietin in cultured Hep3B human hepatocellular c...

journal_title：Planta medica

authors： Chen J,Lam CT,Kong AY,Zhang WL,Zhan JY,Bi CW,Chan GK,Lam KY,Yao P,Dong TT,Tsim KW

更新日期：2014-11-01 00:00:00

abstract：:Seven phenolic derivatives, 2,4-bis(4-hydroxybenzyl)phenol ( 1), bis[4(beta- D-glucopyranosyloxy)-benzyl] ( S)-(-)-2-isopropylmalate ( 2), bis[4-(beta- D-gluco-pyranosyloxy)benzyl] ( S)-(-)-2-sec-butylmalate ( 3), 4-hydroxybenzyaldehyde ( 4), 4,4'-dihydroxydiphenyl-methane ( 5), 4-hydroxybenzyl alcohol ( 6), and 4-(be...

journal_title：Planta medica

authors： Yi-Ming L,Zhuo-Lun Z,Yong-Fu H

更新日期：1993-08-01 00:00:00

abstract：:The chloroform extract of the stems of Encelia ventorum yielded a new benzopyranbenzofuran dimer. The structure was assigned from (1)H-NMR and MS data as 4[2-(5-acetyl-6-hydroxybenzofuranyl)]-2-[6(7-methoxy-2, 2-dimethylbenzo-1 -pyranyl)]-pentan-2-ol. ...

journal_title：Planta medica

authors： Proksch P,Aregullin M,Rodriguez E

更新日期：1983-04-01 00:00:00

abstract：:This paper reports the phytochemical investigation of the 50% aq. EtOH extract of Houttuynia cordata, an effective TCM and functional food in China, which led to the isolation of 17 flavonoids including four new ones. The four new compounds were flavonoid derivatives tethered with houttuynin (3-oxododecanal). Each of ...

journal_title：Planta medica

authors： Chen SD,Li T,Gao H,Zhu QC,Lu CJ,Wu HL,Peng T,Yao XS

更新日期：2013-12-01 00:00:00

abstract：:This Paper describes an improved HPLC method for the determination of pentacyclic oxindole alkaloids in Uncaria tomentosa (Cat's Claw). Six of the isomeric compounds could be baseline separated at room temperature within less than 30 min by using 3 microm C-18 column material and a mobile phase consisting of 10 mM pho...

journal_title：Planta medica

authors： Ganzera M,Muhammad I,Khan RA,Khan IA

更新日期：2001-07-01 00:00:00

abstract：:Swertiamarin, a secoiridoid isolated from the ethyl acetate extract of Enicostemma axillare, was evaluated for antiedematogenic activity using carrageenan-, formalin-, and histamine-induced paw edema methods in rats. In the carrageenan-induced method, the percentages of edema inhibition obtained after 5 h induction we...

journal_title：Planta medica

authors： Vaijanathappa J,Badami S

更新日期：2009-01-01 00:00:00

abstract：:In this study the skin permeation and the topical anti-inflammatory properties of ginger extracts were investigated. A commercial ginger dry extract (DE) and a gingerols-enriched dry extract (EDE) were evaluated for their in vivo topical anti-inflammatory activity by inhibition of Croton oil-induced ear oedema in mice...

journal_title：Planta medica

authors： Minghetti P,Sosa S,Cilurzo F,Casiraghi A,Alberti E,Tubaro A,Loggia RD,Montanari L

更新日期：2007-12-01 00:00:00

abstract：:Five new dibenzocyclooctane lignans, schisanwilsonins K-O, together with eighteen known lignans were isolated from the stems of Schisandra wilsoniana. The structures of these new compounds were elucidated by spectroscopic methods, including 2D-NMR techniques. Several compounds were found to show anti-HIV and anti-HBV ...

journal_title：Planta medica

authors： Ma WH,Lu Y,Chen DF

更新日期：2013-08-01 00:00:00

abstract：:Rutaecarpine is an alkaloid originally isolated from the unripe fruit of Evodia rutaecarpa. Recently, rutaecarpine has been characterized to have an anti-inflammatory activity through cyclooxygenase-2 inhibition. In the present studies, the effects of rutaecarpine on liver cytochrome P450 s (P450s) and P450 s involved...

journal_title：Planta medica

authors： Lee SK,Kim NH,Lee J,Kim DH,Lee ES,Choi HG,Chang HW,Jahng Y,Jeong TC

更新日期：2004-08-01 00:00:00

abstract：:Isoliquiritigenin (4,2',4'-trihydroxychalcone, ISL) is a natural pigment with a simple chalcone structure. In this study, we report the ISL-induced inhibition on the growth of human hepatoma cells (Hep G2) for the first time. The cell growth inhibition achieved by ISL treatment resulted in programmed cell death in a c...

journal_title：Planta medica

authors： Hsu YL,Kuo PL,Lin LT,Lin CC

更新日期：2005-02-01 00:00:00

abstract：:Infections caused by HSV-2 are a public health concern worldwide, and there is still a great demand for the discovery of novel anti-herpes virus agents effective against strains resistant to current antiviral agents. In this context, medicinal plants represent an alternative source of active compounds for developing e...

journal_title：Planta medica

authors： Rittà M,Marengo A,Civra A,Lembo D,Cagliero C,Kant K,Lal UR,Rubiolo P,Ghosh M,Donalisio M

更新日期：2020-03-01 00:00:00

abstract：:This study evaluated the susceptibility of oral pathogenic microorganisms Candida albicans, Streptococcus mutans, Staphylococcus aureus, and Aggregatibacter actinomycetemcomitans to Brazilian medicinal plant extracts of Schinus terebinthifolius (aroeira), Croton campestris (velame), Lafoensia pacari (pacari), Centauri...

journal_title：Planta medica

authors： Pereira EM,Gomes RT,Freire NR,Aguiar EG,Brandão Md,Santos VR

更新日期：2011-03-01 00:00:00

abstract：:TLC autographic assays revealed in the CH(2)Cl(2) extract of Tinospora crispa Miers (Menispermaceae) the presence of three compounds exhibiting antioxidant and radical scavenging properties towards beta-carotene and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. They were isolated and identified as N-CIS-feruloyltyrami...

journal_title：Planta medica

authors： Cavin A,Hostettmann K,Dyatmyko W,Potterat O

更新日期：1998-06-01 00:00:00

abstract：:Four new neolignan glucosides, longiflorosides A, B, C and D, in addition to one known neolignan glucoside, dehydro-diconiferyl alcohol-4-O-beta-D-glucopyranoside were obtained from whole plants of Pedicularis longiflora. The structures of these compounds were determined mainly on spectral evidence. ...

journal_title：Planta medica

authors： Wang CZ,Jia ZJ

更新日期：1997-06-01 00:00:00

abstract：:Emodin, chrysophanol and physcion have been shown to be the major anthraquinone pigments present in the dry roots of RUMEX ABYSINICA. ...

journal_title：Planta medica

authors： Munavu RM,Mudamba LO,Ogur JA

更新日期：1984-02-01 00:00:00

abstract：:This paper studies the effect of different concentrations of ethephon on the levels of the sesquiterpene, nootkatone, and of the flavanones, naringin and narirutin, in grapefruit fruits. The results show that nootkatone synthesis and/or accumulation was stimulated by all the concentrations of ethephon assayed, while t...

journal_title：Planta medica

authors： Puig DG,Pérez ML,Fuster MD,Ortuño A,Sabater F,Porras I,Lidón AG,Del Río JA

更新日期：1995-06-01 00:00:00

abstract：:One new diterpene, 2 alpha-hydroxy-12beta-hydroxy-isopimara-8(14), 15-diene, and six known compounds as triterpenes, sterols and fatty acid, were isolated from the stem bark of Tanaecium jaroba (Bignoniaceae), a Bolivian plant used in traditional medicine. Their structures were established mainly by 1D and 2D NMR (COS...

journal_title：Planta medica

authors： Mitaine-Offer AC,Sauvain M,Deharo E,Muñoz V,Zèches-Hanrot M

更新日期：2002-06-01 00:00:00

abstract：:Two indole alkaloids were isolated from the culture of Aspergillus fumigatus (strain No. CY018), an endophytic fungus harboring inside the elder leaf of Cynodon dactylon. These two chemicals were identified as fumigaclavine C and fumitremorgin C. In screening the bioactivity of these two indole alkaloids, their vasore...

journal_title：Planta medica

authors： Ma HY,Song YC,Mao YY,Jiang JH,Tan RX,Luo L

更新日期：2006-04-01 00:00:00

abstract：:The purpose of this study was to investigate dermal pharmacokinetics of terpinen-4-ol in rats following topical administration of plai oil derived from the rhizomes of Zingiber cassumunar Roxb. Unbound terpinen-4-ol concentrations in dermal tissue were measured by microdialysis. The dermal pharmacokinetic study of ter...

journal_title：Planta medica

authors： Chooluck K,Singh RP,Sathirakul K,Derendorf H

更新日期：2012-11-01 00:00:00

abstract：:A procedure is described for the extraction of both anthraquinones and alkaloids from tissue culture material of CINCHONA species. Using this extraction method, it is possible to quantitatively determine the two groups of secondary metabolites produced in CINCHONA tissue cultures. ...

journal_title：Planta medica

authors： Wijnsma R,van Vliet TB,Harkes PA,van Groningen HJ,van der Heijden R,Verpoorte R,Svendsen AB

更新日期：1987-02-01 00:00:00

abstract：:Endothelial dysfunction is characterised by the low bioavailability of nitric oxide with a relevant negative impact on the nitric oxide/cGMP pathway. The loss of nitric oxide/cGMP signaling may be caused by an increased arginase activity. Plant-derived substances, especially polyphenols, are compounds that have the po...

journal_title：Planta medica

authors： Minozzo BR,Fernandes D,Beltrame FL

更新日期：2018-03-01 00:00:00

abstract：:The indole alkaloid content of RAUWOLFIA SERPENTINA roots from regenerated plants (from stem-and root-callus) was compared with the parental stock. Although the total alkaloid content seems to be slightly higher in the roots from regenerated plants, HPLC-analysis of individual alkaloids indicated that the contents of ...

journal_title：Planta medica

authors： Ruyter CM,Akram M,Illahi I,Stöckigt J

更新日期：1991-08-01 00:00:00

abstract：:Herpes simplex virus infections persist throughout the lifetime of the host and affect more than 80 % of the humans worldwide. The intensive use of available therapeutic drugs has led to undesirable effects, such as drug-resistant strains, prompting the search for new antiherpetic agents. Although diverse bioactivitie...

journal_title：Planta medica

authors： Nocchi SR,Companhoni MV,de Mello JC,Dias Filho BP,Nakamura CV,Carollo CA,Silva DB,Ueda-Nakamura T

更新日期：2017-04-01 00:00:00

abstract：:Three compounds with anti-inflammatory activity were isolated from Schinus molle fruits. Two of the compounds were identified as 3- epi-isomasticadienolalic acid ( 1), isomasticadienonalic acid ( 2) and chamaejasmin ( 3). Triterpenes 1 and 2, and biflavanone 3 were tested on two models of mice paw inflammation: one of...

journal_title：Planta medica

authors： Yueqin Z,Recio MC,Máñez S,Giner RM,Cerdá-Nicolás M,Ríos JL

更新日期：2003-10-01 00:00:00

abstract：:Thyme extract is known to posses spasmolytic effects on isolated trachea and to increase ciliary activity. A small part of this effect is mediated via beta (2) receptors, but other receptors are supposed to be involved. Endothelin has a pathophysiological impact in asthma with respect to hyper-reagibility and contract...

journal_title：Planta medica

authors： Engelbertz J,Schwenk T,Kinzinger U,Schierstedt D,Verspohl EJ

更新日期：2008-10-01 00:00:00

abstract：:A simple and efficient method for the separation of the three phenolic diketones, curcumin 1, demethoxycurcumin 2, and bis-demethoxycurcumin 3, isolated from the rhizomes of Curcuma longa has been developed. The method is of general applicability for the separation of compounds containing acidic and chelating groups a...

journal_title：Planta medica

authors： Rasmussen HB,Christensen SB,Kvist LP,Karazmi A

更新日期：2000-05-01 00:00:00

abstract：:Ganoderan B increased the plasma insulin level in normal and glucose-loaded mice but elicited no effect on insulin binding to isolated adipocytes. Administration of ganoderan B elicited significant increases of the activities of hepatic glucokinase, phosphofructokinase and glucose-6-phosphate dehydrogenase, decreased ...

journal_title：Planta medica

authors： Hikino H,Ishiyama M,Suzuki Y,Konno C

更新日期：1989-10-01 00:00:00

abstract：:This review describes the current status of the development of techniques combining liquid chromatography and nuclear magnetic resonance and their use in the context of natural products. HPLC-NMR methods have a rapidly growing impact on natural products research by enabling structure determination of natural products ...

journal_title：Planta medica

authors： Jaroszewski JW

更新日期：2005-08-01 00:00:00