Neolignan glycosides from Pedicularis longiflora.

abstract：:Four p-terphenyl derivatives named curtisians I-L (1-4) were isolated from the MeOH extract of the fruit bodies of Paxillus curtisii. Their structures were elucidated by 2D NMR, MS, IR and UV spectroscopy and chemical reaction. The absolute configurations of curtisians were determined by GC-MS on a chiral column of th...

journal_title：Planta medica

authors： Quang DN,Hashimoto T,Nukada M,Yamamoto I,Tanaka M,Asakawa Y

更新日期：2003-11-01 00:00:00

abstract：:Gleditsioside E, a triterpene saponin isolated from Gleditsia sinensis, showed significant cytotoxicity against Bel-7402, BGC-823, HeLa, HL-60 and MCF-7 cell lines. The results of flow cytometry with annexin V-FITC/PI double staining proved that gleditsioside E mainly induced early apoptosis in HL-60 cells. Gleditsios...

journal_title：Planta medica

authors： Zhong L,Qu G,Li P,Han J,Guo D

更新日期：2003-06-01 00:00:00

abstract：:Two new secodammarane triterpenoid saponins were isolated from the leaves of Cyclocarya paliurus. Based on chemical and spectral analysis they were assigned as (20S)-20-hydroxy-24-O-alpha-L-arabino-pyranosyl-3,4- secodammar-4(28),11,25-trien-3-oic acid, named cyclocarioside II and 25-hydroxy-(20S,24R)-epoxy-12R-O-beta...

journal_title：Planta medica

authors： Shu RG,Xu CR,Li LN,Yu ZL

更新日期：1995-12-01 00:00:00

abstract：:The dichloromethane-soluble fraction of the methanol extract of the stem bark of Millettia versicolor Welw. (Leguminosae) has been shown to possess anti-inflammatory activity. The chromatographic fractionation and subsequent analysis of the spectroscopic data of this extract led to the isolation and identification of ...

journal_title：Planta medica

authors： Fotsing MT,Yankep E,Njamen D,Fomum ZT,Nyasse B,Bodo B,Recio MC,Giner RM,Ríos JL

更新日期：2003-08-01 00:00:00

abstract：:Two new lactones, 1 and 2, together with five known compounds, 3-7, were isolated from the marine mangrove fungus Xylaria sp. BL321. Their structures were determined by comprehensive analysis of their MS and NMR spectroscopic data. The absolute configurations of 1 and 2 were established on the basis of electronic circ...

journal_title：Planta medica

authors： Song YX,Wang J,Li SW,Cheng B,Li L,Chen B,Liu L,Lin YC,Gu YC

更新日期：2012-01-01 00:00:00

abstract：:The purpose of this study was to observe the protective effects of α-boswellic acids on hypoxia-induced pulmonary vascular structural remodeling in pulmonary arterial smooth muscle cells in a hypertensive rat model. Pulmonary arterial smooth muscle cells were cultured and then randomly divided into four groups: normox...

journal_title：Planta medica

authors： Xiao B,Zhang G,Ali Sheikh MS,Shi R

更新日期：2017-01-01 00:00:00

abstract：:Bisbenzylisoquinoline alkaloids are known to affect immune responses as well as inflammatory responses, and have been used for the treatment of inflammatory symptoms in China. This study is aimed at elucidating the inhibitory effects of two alkaloids, fangchinoline and isotetrandrine, on the induction of the proinflam...

journal_title：Planta medica

authors： Onai N,Tsunokawa Y,Suda M,Watanabe N,Nakamura K,Sugimoto Y,Kobayashi Y

更新日期：1995-12-01 00:00:00

abstract：:The preventive effects of hydroxychalcone derivatives on ulcer formation induced by severe necrotizing agents such as 60% ethanol in 150 mM HCl (HCl-ethanol) and 0.2 N NaOH in rats were examined. Among the compounds tested, 2',4'-dihydroxychalcone gave the strongest activity in both experimental models and protected t...

journal_title：Planta medica

authors： Yamamoto K,Kakegawa H,Ueda H,Matsumoto H,Sudo T,Miki T,Satoh T

更新日期：1992-10-01 00:00:00

abstract：:3beta-Acetoxy-17beta-hydroxy-androst-5-ene was isolated from aerial parts of Acacia nilotica (L.) Willd (Mimosaceae). The structure of this compound was established by spectral analysis and single crystal X-ray diffraction analysis. The steroid showed dose-dependent anti-inflammatory activity against TPA-induced mouse...

journal_title：Planta medica

authors： Chaubal R,Mujumdar AM,Puranik VG,Deshpande VH,Deshpande NR

更新日期：2003-03-01 00:00:00

abstract：:A sensitive and rapid liquid chromatography-mass spectrometric method for the determination of ophiopogonin D in rat plasma was developed and validated. Chromatographic separation was performed on a C (18) column using a step gradient program with the mobile phase of 0.5 mmol/L ammonium chloride solution and acetonitr...

journal_title：Planta medica

authors： Xia CH,Sun JG,Hao HP,Wang GJ,Yan B,Gu SH,Zheng CN,Shang LL,Roberts MS

更新日期：2008-12-01 00:00:00

abstract：:When added to suspension cultures of CATHARANTHUS ROSEUS, abscisic acid (ABA) stimulated intracellular accumulation of the indole alkaloids catharanthine and ajmalicine in both flask and 30 litre fermenter-scale systems. The response varied, and depended upon the cell line, the concentration and source of the ABA, and...

journal_title：Planta medica

authors： Smith JI,Smart NJ,Kurz WG,Misawa M

更新日期：1987-10-01 00:00:00

abstract：:Ten flavonoid glycosides were identified in flowers of HETEROTHECA INULOIDES ("Mexican Arnica"). Their structures were established by spectral data (UV, (1)H-NMR, (13)C-NMR, mass) and total acid hydrolysis as kaempferol 3-beta-glucoside, 3-beta-galactoside, 3-beta-rutinoside, 3-beta-robinobioside, quercetin 3-beta-glu...

journal_title：Planta medica

authors： Jerga C,Merfort I,Willuhn G

更新日期：1990-08-01 00:00:00

abstract：:d-Dicentrine was isolated from the root of Lindera megaphylla. It inhibited the aggregation of washed rabbit platelets induced by ADP, collagen, arachidonic acid, and PAF. It also inhibited the high potassium- and norepinephrine-induced contraction of rat thoracic aorta. In rat ventricular cells treated with 3 microM ...

journal_title：Planta medica

authors： Chen CC,Huang YL,Ou JC,Su MJ,Yu SM,Teng CM

更新日期：1991-10-01 00:00:00

abstract：:A mixture of cyanogenic glucosides epivolkenin and taraktophyllin, 1,4-dihydroxy-2-cyclopentenecarboxamide, and uridine were isolated from leaves of Lindackeria dentata (Flacourtiaceae). Another cyclopentanoid amide, (1 R,4 S,5 R)-1,4,5-trihydroxy-2-cyclopentenecarboxamide, was synthesized in two steps from gynocardin...

journal_title：Planta medica

authors： Jaroszewski JW,Ekpe P,Witt M

更新日期：2004-10-01 00:00:00

abstract：:Water-soluble and alkaline-soluble polysaccharide fractions, prepared from roots and leaves of PANAX GINSENG C.A. Meyer, were fractionated into strongly acidic, weakly acidic, and neutral polysaccharide fractions by cetyltrimethyammonium bromide, respectively. The roots contained a larger amount of crude polysaccharid...

journal_title：Planta medica

authors： Gao QP,Kiyohara H,Cyong JC,Yamada H

更新日期：1989-02-01 00:00:00

abstract：:The effect of a lignan-enriched extract of the fruits of Schisandra chinensis (FS) on hepatic glutathione (GSH) status was examined in both control and carbon tetrachloride (CCl4)-treated rats. FS treatment caused a dose-dependent enhancement in hepatic GSH status, as evidenced by significant increases in hepatic GSH ...

journal_title：Planta medica

authors： Ko KM,Ip SP,Poon MK,Wu SS,Che CT,Ng KH,Kong YC

更新日期：1995-04-01 00:00:00

abstract：:The aggregation of the microtubule-associated protein tau is a significant event in many neurodegenerative diseases including Alzheimer's disease. The inhibition or reversal of tau aggregation is therefore a potential therapeutic strategy for these diseases. Fungal natural products have proven to be a rich source of u...

journal_title：Planta medica

authors： Paranjape SR,Chiang YM,Sanchez JF,Entwistle R,Wang CC,Oakley BR,Gamblin TC

更新日期：2014-01-01 00:00:00

abstract：:The effects of four fractions, a hexane fraction, an ethyl acetate fraction, an N-butanol fraction and a water fraction, from a water extract of Herba Visci were investigated to find the fraction, in IN VITRO experiments, with the greatest ability to inhibit the formation of osteoclast-like multinucleated cells from m...

journal_title：Planta medica

authors： Yin J,Han N,Xu X,Liu Z,Zhang B,Kadota S

更新日期：2008-02-01 00:00:00

abstract：:An ionpair-HPLC-technic using a reversed-phase column was developed to screen plant extracts for cardiotonic amines and to isolate them in a preparative scale for direct MS and pharmacological investigations. By this method the positive inotropic tyramine could be isolated from Selenicereus grandiflorus (L.) Britt et ...

journal_title：Planta medica

authors： Wagner H,Grevel J

更新日期：1982-01-01 00:00:00

abstract：:The crude ethanol extract from the leaves of Dendropanax arboreus (Araliaceae) from Monteverde, Costa Rica, exhibits cytotoxic activity against Hep-G2, A-431, H-4IIE, and L-1210 tumor cell lines, but is not toxic against normal hepatocytes. The active component has been isolated by activity-directed separation and ide...

journal_title：Planta medica

authors： Setzer WN,Green TJ,Whitaker KW,Moriarity DM,Yancey CA,Lawton RO,Bates RB

更新日期：1995-10-01 00:00:00

abstract：:The aim of the present study was to investigate the antistress potential of LABISIA PUMILA aqueous extract (LPPM/A003) using a battery of tests widely employed in different stressful situations. Pretreatment of experimental animals with LPPM/A003 caused an increase in the swimming endurance and hypoxia time and also s...

journal_title：Planta medica

authors： Kour K,Sharma N,Chandan BK,Koul S,Sangwan PL,Bani S

更新日期：2010-10-01 00:00:00

abstract：:Six diarylheptanoids were isolated from the rhizome of Alpinia officinarum (Zingiberaceae) as inhibitors of nitric oxide (NO) production in the lipopolysaccharide-activated macrophage cell line RAW 264.7. A double bond at C-4 of the linker between two aromatic rings was found to be essential for activity. Furthermore,...

journal_title：Planta medica

authors： Lee HJ,Kim JS,Ryu JH

更新日期：2006-01-01 00:00:00

abstract：:Aerial parts of Pterocaulon polystachyum from Chaco province, Argentina, afforded the known coumarins ayapin, isoscopoletin, prenyletin, prenyletin methyl ether, virgatenol, obtusinin, 5-methoxy-6,7-methylenedioxycoumarin, 5-(3,3-dimethylallyloxy)-6,7-methylenedioxycoumarin, 5-(2',3'-dihydroxy-3-methylbutanoxy)-6,7-me...

journal_title：Planta medica

authors： Vera N,Bardón A,Catalán CA,Gedris TE,Herz W

更新日期：2001-10-01 00:00:00

abstract：:Diabetes mellitus is one of the major health problems in Africa. The conventional oral synthetic antidiabetic drugs available to manage the disease are costly and not readily affordable to the majority of the affected population. Interestingly, the continent is endowed with a tremendous number of medicinal plants that...

journal_title：Planta medica

authors： Mohammed A,Ibrahim MA,Islam MS

更新日期：2014-03-01 00:00:00

abstract：:A novel experimental model of free radical-induced emesis for screening anti-emetic compounds from natural sources was established. 2,2'-Azobis(2-amidinopropane) dihydrochloride (AAPH) dissolved in liposome induced emesis in young chickens, and the emesis was prevented by antioxidants including N-(2-mercaptopropionyl)...

journal_title：Planta medica

authors： Yang Y,Kinoshita K,Koyama K,Takahashi K,Tai T,Nunoura Y,Watanabe K

更新日期：1999-08-01 00:00:00

abstract：:The inhibitory activity of stilbenes isolated from medicinal plants on cell adhesion molecules on the surface of THP-1 human monocytic cell lines was investigated. Among ten stilbenes tested, four stilbenes displayed a significant inhibitory activity on the expression of both intercellular adhesion molecule-1 (ICAM-1)...

journal_title：Planta medica

authors： Ahn KS,Kim JH,Oh SR,Ryu SY,Lee HK

更新日期：2000-10-01 00:00:00

abstract：:From the methanolic extract of the whole plants of Bidens pilosa the new beta-D-glucopyranosyloxy-3-hydroxy-6(E)-tetradecen-8, 10,12-triyne besides a known polyine has been isolated and identified mainly by IR and NMR methods. The new compound showed overgrowing action against normal and transformed human cell lines i...

journal_title：Planta medica

authors： Alvarez L,Marquina S,Villarreal ML,Alonso D,Aranda E,Delgado G

更新日期：1996-08-01 00:00:00

abstract：:From the rhizomes of HYPOXIS OBTUSA two monoglucosides having the same aglycone as hypoxoside, 1-(3',4'- dihydroxyphenyl)-5-(3'',4''-dihydroxyphenyl)-1-pen-ten-4-yne, have been obtained. By methylation followed by hydrogenation they have been transformed into the same compound, 1-(3'-methoxy-4'- O-beta- D-glucopyranos...

journal_title：Planta medica

authors： Galeffi C,Multari G,De Vicente Y,Messana I,Nicoletti M,Marini-Bettolo GB

更新日期：1989-06-01 00:00:00

abstract：:Four new isoprenylated xanthones, cudraxanthones A, B and C were isolated from the N-hexane extract of the root bark of CUDRANIA TRICUSPIDATA (Carr.) Bur. (Japanese name "Hariguwa"; Moraceae), and cudraxanthone D from the benzene extract. The structures of cudraxanthones A, B, C and D were shown to be 1-4, respectivel...

journal_title：Planta medica

authors： Fujimoto T,Hano Y,Nomura T

更新日期：1984-06-01 00:00:00

abstract：:Embelia ribes Burm. f. (Myrsinaceae) is one of the important plants used in Indian traditional medicine. RAPD-PCR analysis was performed to obtain species-specific DNA fragments. A band of 906 bp that was specific to Embelia ribes irrespective of the geographical source was obtained using the random decamer primer OPF...

journal_title：Planta medica

authors： Devaiah KM,Venkatasubramanian P

更新日期：2008-02-01 00:00:00