Abstract:
:A museum collection of Cinchonae cortex samples (n = 117), from the period 1850-1950, was extracted with a mixture of chloroform-d1, methanol-d4, water-d2, and perchloric acid in the ratios 5 : 5 : 1 : 1. The extracts were directly analyzed using 1H NMR spectroscopy (600 MHz) and the spectra evaluated using principal component analysis (PCA) and total statistical correlation spectroscopy (STOCSY). A new method called STOCSY-CA, where CA stands for component analysis, is described, and an analysis using this method is presented. It was found that the samples had a rather homogenous content of the well-known cinchona alkaloids quinine, cinchonine, and cinchonidine without any apparent clustering. Signals from analogues were detected but not in substantial amounts. The main variation was related to the absolute amounts of extracted alkaloids, which was attributed to the evolution of the Cinchona tree cultivation during the period in which the samples were collected.
journal_name
Planta Medjournal_title
Planta medicaauthors
Yilmaz A,Nyberg NT,Jaroszewski JWdoi
10.1055/s-0032-1315396subject
Has Abstractpub_date
2012-11-01 00:00:00pages
1885-90issue
17eissn
0032-0943issn
1439-0221journal_volume
78pub_type
历史文章,杂志文章相关文献
PLANTA MEDICA文献大全abstract::An allergenic protein from tatary buckwheat seeds, designated TBt, was purified by salting out, anion exchange chromatography and size exclusion chromatography (SEC). Analysis by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and SEC showed that the allergenic protein was composed of two subunits...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0028-1088319
更新日期:2008-12-01 00:00:00
abstract::In this study the skin permeation and the topical anti-inflammatory properties of ginger extracts were investigated. A commercial ginger dry extract (DE) and a gingerols-enriched dry extract (EDE) were evaluated for their in vivo topical anti-inflammatory activity by inhibition of Croton oil-induced ear oedema in mice...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-993741
更新日期:2007-12-01 00:00:00
abstract::A novel bibenzyl, a new bibenzyl, two new phenanthrenes, and a new lignin glycoside, namely longicornuol A (1), 4-[2-(3-hdroxyphenol)-1-methoxyethyl]-2,6-dimethoxyphenol (2), 5-hydroxy-7-methoxy-9,10-dihydrophenanthrene-1,4-dione (3), 7-methoxy-9,10-dihydrophenanthrene-2,4,5-triol (4) and erythro-1-(4-O-beta-D-glucopy...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1074492
更新日期:2008-04-01 00:00:00
abstract::We have examined the immunosuppressive effects of representative ginsenosides (Rb1, Rb2, Re and Rg1) from Panax ginseng C. A. Meyer on CD4+ and CD8+ lymphocyte proliferation. Ginsenosides differentially modulated lymphocyte proliferation induced by concanavalin A (Con A), lipopolysaccharide (LPS), phytohemaglutinin (P...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-32556
更新日期:2002-06-01 00:00:00
abstract::A beta-hydroxychalcone 1, so far not reported as a natural compound, was separated from the diethyl ether extract of LEPTOSPERMUM SCOPARIUM (Myrtaceae). Furthermore, three known flavonoids 2-4 were isolated. The (13)C-NMR spectra of 2-4 are reported, since they have as yet not been reported in the literature. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959667
更新日期:1993-06-01 00:00:00
abstract::Dihydrogoniothalamin is a styrylpyrone isolated from the leaves of Aniba panurensis. The present work aimed at investigating the vasorelaxant activity of dihydrogoniothalamin and its underlying mechanism of action in the rat aorta. Dihydrogoniothalamin (0.01-100 µM) induced a concentration-dependent vasodilatation of ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0035-1557775
更新日期:2015-10-01 00:00:00
abstract::In obese adipose tissue, tumor necrosis factor-α secreted from macrophages plays an important role in the adipocyte dysfunctions, including insulin resistance, lipolytic acceleration, and changes of adipokines, which promote the development of obesity-related complications. Phillyrin, an active ingredient found in man...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0034-1368614
更新日期:2014-07-01 00:00:00
abstract::Three new secoiridoid glucosides, jasamplexosides A, B and C, were isolated from the crude drug "Niu du teng", the leaves and stems of JASMINUM AMPLEXICAULE, together with the known secoiridoid glucosides, 10-hydroxyligstroside and jasminoside. Their structural elucidation by spectroscopic studies is described. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-961548
更新日期:1992-12-01 00:00:00
abstract::The special extract of Cimicifuga racemosa (CR) BNO 1055 was shown to have bone protective effects without exerting estrogenic effects in the uterus or mammary gland. Whether the effects of CR BNO 1055 would be exerted in other organs that also express estrogen receptors (ERs) but in which the effects of estrogens and...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185561
更新日期:2009-10-01 00:00:00
abstract::O-Methyl (1), O-ethyl (2), and O-butyl (3) 4-[(α-L-rhamnosyloxy) benzyl] thiocarbamate (E), along with 4-(α-L-rhamnosyloxy) benzyl isothiocyanate (4) have been isolated from the aerial parts of Moringa peregrina. The compounds were tested for in vitro activity against Trypanosoma brucei rhodesiense and cytotoxicity in...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0033-1351102
更新日期:2014-01-01 00:00:00
abstract::Fresh Nagami kumquats (Fortunella margarita) were subjected to hydrodistillation using a Clevenger-type apparatus to obtain volatile oil. The chemical composition of the volatile oil was analyzed by GC-MS using Rtx-5 Sil MS and DB Wax columns. A total of 25 volatile compounds were identified by mass spectra, retention...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0031-1298619
更新日期:2012-06-01 00:00:00
abstract::It has been known that silymarin exhibits protective activity against oxidative liver injury induced by various hepatotoxicants, but the underlying mechanism of its beneficial action remains unclear. We determined the alterations in sulfur-containing amino acid metabolism induced by silymarin in association with its e...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1328704
更新日期:2013-08-01 00:00:00
abstract::The aim of this study was to investigate the protective effect of (S)-bakuchiol isolated from the seed of Psoralea corylifolia, on liver injury. Primary rat hepatocyte intoxication was induced by tert-butyl hydroperoxide (tBH), carbon tetrachloride (CCl4) or D-galactosamine (D-GalN). Liver injury was induced by either...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-864150
更新日期:2005-06-01 00:00:00
abstract::Four new benzofurans trans-5-(3-hydroxypropyl)-7-methoxy-2-[2,3-dihydro-3-hydroxymethyl-7-methoxy-2-(3-methoxy-4-hydroxyphenyl)-benzofuran-5-yl]benzofuran (1), (E)-5-(2-formylvinyl)-7-methoxy-2-(3,4-methylenedioxyphenyl)benzofuran (2), 5-(3-butanoyloxypropyl)-7-methoxy-2-(3,4-methylenedioxyphenyl)benzofuran (3), and 5...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-871226
更新日期:2005-09-01 00:00:00
abstract::Andrographolide (Andro) is a potentially anti-inflammatory diterpenoid lactone isolated from the traditional herbal medicine ANDROGRAPHIS PANICULATA, which has been effectively used for the treatment of infection, inflammation, cold, fever and diarrhea in China for centuries. In the current study, we found that Andro ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-990230
更新日期:2007-10-01 00:00:00
abstract::A study of secondary metabolites from the bark of Alnus glutinosa led to the isolation of fourteen diarylheptanoids: oregonin (1), platyphylloside (2), rubranoside A (3), rubranoside B (4), hirsutanonol (5), hirsutenone (6), hirsutanonol-5-O-β-D-glucopyranoside (7), platyphyllonol-5-O-β-D-xylopyranoside (8), aceroside...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1328301
更新日期:2013-04-01 00:00:00
abstract::Chemical studies on the constituents from the dragon's blood of Dracaena cambodiana led to the discovery of three new flavonoid derivatives (1- 3) and six known compounds (4- 9). The structures of the three new compounds were elucidated by NMR and MS spectroscopic analyses. All compounds were evaluated for their growt...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-0031-1280086
更新日期:2011-12-01 00:00:00
abstract::Five known abietane diterpenes, fatty acid esters of 7alpha-acyloxy-6beta-hydroxyroyleanone (1), grandidone A (2), 7alpha-acetoxy-6beta-hydroxyroyleanone (3), 6beta,7alpha-dihydroxyroyleanone (4), and coleon U (5), isolated from Plectranthus grandidentatus Gürke, were evaluated for their in vitro antiproliferative act...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-34407
更新日期:2002-09-01 00:00:00
abstract::One new triterpene, kudinchalactone A (1), and four new triterpenoid saponins, ilekudinchosides A-D (2- 5), were isolated from the leaves of Ilex kudincha C. J. Tseng along with eight known triterpenoids. These new compounds were elucidated by spectroscopic methods including 1D and 2D NMR, HR-TOF-MS, and CD spectra. C...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1271164
更新日期:2011-11-01 00:00:00
abstract::Ten new polyhydroxyolean-12-ene pentacyclic triterpenoidal saponins, named rogchaponins 1-10, were isolated from the methanolic extract of the roots of Camellia sinensis by a series of chromatographic methods (silica gel flash column and C18 MPLC followed by C18 HPLC). Their structures were established by 1D and 2D-NM...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0031-1280024
更新日期:2011-12-01 00:00:00
abstract::Embelia ribes Burm. f. (Myrsinaceae) is one of the important plants used in Indian traditional medicine. RAPD-PCR analysis was performed to obtain species-specific DNA fragments. A band of 906 bp that was specific to Embelia ribes irrespective of the geographical source was obtained using the random decamer primer OPF...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034279
更新日期:2008-02-01 00:00:00
abstract::Medicinal herbs are increasingly used in the search for safe and efficient drug candidates for hepatitis C virus infection. In this study, we have investigated the anti-HCV effect of compounds from Mori Cortex Radicis. During a screening for extracts with anti-HCV affinity from medicinal plants (173 species), the meth...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-990249
更新日期:2007-11-01 00:00:00
abstract::Two triterpenoidal saponins having phytolaccagenin as the aglycone were isolated from the roots of Phytolacca esculenta (Phytolaccaceae). The structures of two new saponins, esculentoside I and esculentoside N, were established to be 3-O-[beta-D-glucopyranosyl-(1----4)-beta-D- glucopyranosyl]-28-O-beta-D-glucopyranosy...
journal_title:Planta medica
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract::Myrrh is the oleo-gum resin of mainly Commiphora molmol and as a powdered substance, one compound in the traditional medicinal product Myrrhinil-Intest®, which has been used for the treatment of unspecific, inflammatory intestinal disorders. The aim of the present study was to evaluate the antispasmodic effect of myrr...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0034-1383391
更新日期:2015-01-01 00:00:00
abstract::Eight compounds were isolated from the CH (2)Cl (2) extracts of ERYTHRINA SENEGALENSIS to assess HIV-1 protease (PR) activity inhibition. The prenylated isoflavone structures, identified by spectroscopic analysis, were 8-prenylluteone ( 1), auriculatin ( 2), erysenegalensein O ( 3), erysenegalensein D ( 4), erysenegal...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0028-1088395
更新日期:2009-02-01 00:00:00
abstract::The antihyperglycemic action of andrographolide, an active principle in the leaves of Andrographis paniculata (Burm. f.) Nees, was investigated in streptozotocin-induced diabetic rats (STZ-diabetic rats). Oral treatment of andrographolide decreased the plasma glucose concentrations of STZ-diabetic rats in a dose-depen...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-45185
更新日期:2003-12-01 00:00:00
abstract::Scopoletin exhibited an immediate and dose-dependent hypouricemic effect after intraperitoneal administration (50, 100, 200 mg/kg) in hyperuricemic mice induced by potassium oxonate; however, it did not affect the serum uric acid level in normal mice at the tested doses. For exploring the involved mechanisms of action...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-837789
更新日期:2005-02-01 00:00:00
abstract::Some diterpenoids show various biological activities, including anti-inflammatory, anti-HIV and anti-tumor activity. Previously, we have focused our research on the apoptosis-inducing properties of diterpenoids and found that some ent-kaurene-type diterpenoids induced apoptosis in human leukemia HL-60 cells. In this s...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-873133
更新日期:2005-11-01 00:00:00
abstract::Effects of passage of subculture and several culture conditions, nutritional, hormonal and light conditions on 3,4-dihydroxyphenylalanine (DOPA) content were examined in callus of STIZOLOBIUM HASSJOO P IPER and T RACY. The favourable conditions for DOPA accumulation were found to be suboptimal conditions for growth, i...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969828
更新日期:1983-10-01 00:00:00
abstract::The chemical composition of the three essential oils obtained by steam distillation of the mastic gum, leaves and twigs of Pistacia lentiscus var. chia, was studied by GC/MS. Sixty nine constituents were identified from the oils. alpha-Pinene, myrcene, trans-caryophyllene and germacrene D were found to be the major co...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-960856
更新日期:1999-12-01 00:00:00