Abstract:
:Chemical studies on the constituents from the dragon's blood of Dracaena cambodiana led to the discovery of three new flavonoid derivatives (1- 3) and six known compounds (4- 9). The structures of the three new compounds were elucidated by NMR and MS spectroscopic analyses. All compounds were evaluated for their growth inhibitory activity against human cell lines K-562, SMMC-7721, and SGC-7901, as well as antibacterial activities against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA). As a result, compounds 1, 2, 5, 7, and 9 showed cytotoxicity against K-562, SMMC-7721, and SGC-7901 cell lines. All these compounds were observed to exhibit antibacterial activities against S. aureus, and compounds 1- 4, 6, 8, and 9 were observed to exhibit antibacterial activity against MRSA.
journal_name
Planta Medjournal_title
Planta medicaauthors
Luo Y,Wang H,Zhao YX,Zeng YB,Shen HY,Dai HF,Mei WLdoi
10.1055/s-0031-1280086subject
Has Abstractpub_date
2011-12-01 00:00:00pages
2053-6issue
18eissn
0032-0943issn
1439-0221journal_volume
77pub_type
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