Abstract:
:Natural products research is increasingly turning to marine animals, plants, and microbes as source organisms. Several marine natural products are currently in preclinical and clinical evaluation, others show promising biological activities in in vitro and in vivo assays. Investigations of biological and chemical ecological phenomena in the marine world will contribute to a better understanding of marine habitats, and also provide a more founded basis regarding the search for pharmaceutically useful marine natural products.
journal_name
Planta Medjournal_title
Planta medicaauthors
König GM,Wright ADdoi
10.1055/s-2006-957861subject
Has Abstractpub_date
1996-06-01 00:00:00pages
193-211issue
3eissn
0032-0943issn
1439-0221journal_volume
62pub_type
杂志文章,评审相关文献
PLANTA MEDICA文献大全abstract::Enzymatic thrombin activity is significantly inhibited only by a few selected natural phenolic compounds (myricetin, rosmarinic acid, caffeic acid phenethyl ester) but more strongly by unsaturated fatty acids like erucic acid and oleic acids. Compared to the inhibitory potential against neutrophil elastase, thrombin a...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-871253
更新日期:2005-08-01 00:00:00
abstract::Isoplexis is a plant genus closely related to Digitalis. Members of this genus contain cardenolides considered more "primitive" than those present in Digitalis. Isoplexis plants, tissue cultures, and isolated cardenolides may thus be used to elucidate the biosynthesis of cardenolides in the Scrophulariaceae. Therefore...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957937
更新日期:1996-10-01 00:00:00
abstract::Alpinia galanga, or galangal, has been a popular condiment used in Thai and Asian cuisine for many years. However, relatively little is known of the potential beneficial or adverse health effects of this spice. This study was conducted to analyze the capacity of galangal extract to induce cytotoxicity and DNA damage i...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-981542
更新日期:2007-07-01 00:00:00
abstract::The traditional therapeutic indications for the use of Morinda citrifolia L. (Rubiaceae) have been investigated. The lyophilised aqueous extract of roots of M. citrifolia was evaluated for analgesic and behavioural effects in mice. The extract did not exhibit any toxic effects but did show a significant, dose-related,...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-961004
更新日期:1990-10-01 00:00:00
abstract::Thalivarmine and thalsivasine, together with the known bases thalmelatidine, thalicberine, O-methylthalicberine, thaliphylline, thalmethine, O-methylthalmethine and (-)- N-methylcanadine have been isolated from the above ground parts of THALICTRUM MINUS var. MINUS L. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969547
更新日期:1985-10-01 00:00:00
abstract::Aerial parts of Pterocaulon polystachyum from Chaco province, Argentina, afforded the known coumarins ayapin, isoscopoletin, prenyletin, prenyletin methyl ether, virgatenol, obtusinin, 5-methoxy-6,7-methylenedioxycoumarin, 5-(3,3-dimethylallyloxy)-6,7-methylenedioxycoumarin, 5-(2',3'-dihydroxy-3-methylbutanoxy)-6,7-me...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-17365
更新日期:2001-10-01 00:00:00
abstract::Using exhaustive chromatographic separation we have isolated (-)-tigloyl-deangeloyl-gomisin F as a novel dibenzocyclooctadiene lignan from schisandra chinensis. With the help of HPLC, we further isolated (+)-schisandrin, (+)-deoxyschisandrin, (+)-γ-schisandrin, (-)-gomisin J, (+)-gomisin A, (-)-gomisin N, (-)-tigloyl-...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1249861
更新日期:2010-10-01 00:00:00
abstract::Three pyrrolizidine alkaloids were isolated from Eupatorium portoricense and their structures elucidated by spectroscopic methods as (-)-viridifloryl-supinidine (amabiline), (-)-viridifloryl-heliotridine (echinatine), and C12- O-acetyl-(-)-viridifloryl-heliotridine (O(12)-acetylechinatine). ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-958112
更新日期:1995-08-01 00:00:00
abstract::Cannabis (Cannabis sativa L.) is an annual herbaceous plant that belongs to the family Cannabaceae. Trans-Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) are the two major phytocannabinoids accounting for over 40% of the cannabis plant extracts, depending on the variety. At the University of Mississippi, differ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-124088
更新日期:2018-03-01 00:00:00
abstract::Ginkgetin, a biflavone isolated from Ginkgo biloba leaves, was previously reported as an inhibitor of group II phospholipase A2. In this study, ginkgetin was evaluated for in vivo antiarthritic and analgesic activities. Ginkgetin (10-20 mg/kg/day) strongly reduced arthritic inflammation in an animal model of rat adjuv...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-960815
更新日期:1999-06-01 00:00:00
abstract::Two new xanthones, caledonixanthone M 1 and caloxanthone L 2, and one new acid, caledonic acid 6 were isolated from the hexane-soluble extract of the stem bark of Calophyllum caledonicum. In the course of this phytochemical study, seven other known compounds - calothwaitesixanthone, calozeyloxanthone, allanxanthone, i...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-818004
更新日期:2003-12-01 00:00:00
abstract::As part of a study on chemical constituents of Camptotheca species, one new natural camptothecin analogue (2), two new alkaloids (3, 4), one new ellagic acid analogue (5), and 19 known compounds (1, 6-23) have been isolated from the root bark, stem bark, fruits, and leaves of Camptotheca acuminata Decaisne. The struct...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2004-835854
更新日期:2004-12-01 00:00:00
abstract::The ethanolic extract of Ilex aquifolium L. (Aquifoliaceae) concentration-dependently inhibited leukotriene B4 biosynthesis in isolated bovine PMNL with an IC50 value of about 60 micrograms/ml, whereas the effect on epidermal 12(S)-HETE biosynthesis was much less pronounced. The extract also inhibited the non-enzymati...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957509
更新日期:1998-08-01 00:00:00
abstract::Hot water extract (ALR-0) of rhizomes of Atractylodes lanceo DC. was fractionated into MeOH-soluble fraction (ALR-1), supernatant fraction of EtOH precipitation (ALR-3 + 4), and crude polysaccharide fraction (ALR-5). Among these fractions, only ALR-5 showed potent stimulating activity for proliferation of bone marrow ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957564
更新日期:1998-12-01 00:00:00
abstract::Turmeric has been extensively utilized in Indian and Chinese medicine for its immune-modulatory properties. Dendritic cells (DCs) are antigen-presenting cells specialized to initiate and regulate immunity. The ability of DCs to initiate immunity is linked to their activation status. The effects of turmeric on human DC...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0028-1088367
更新日期:2009-03-01 00:00:00
abstract::The phytochemical investigation of the aerial parts of LACTUCA SALIGNA L. revealed the presence of lactucin, lactucopicrin, and a new guaianolide named 11beta,13-dihydrolactucopicrin. The structural configuration was established through spectral data. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960064
更新日期:1991-04-01 00:00:00
abstract::Activator protein 1 (AP-1) is a transcription factor which plays a critical role in inflammation and carcinogenesis. The present study was conducted to investigate the effect of berberine, an isoquinoline alkaloid present in plants of the genera Berberis and Coptis, on the activity of AP-1 using a reporter gene assay ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-960795
更新日期:1999-05-01 00:00:00
abstract::A new indole alkaloid, galanthindole, was isolated from Galanthus plicatus ssp. byzantinus (Amaryllidaceae), a plant native to northwestern Turkey. Incorporating a non-fused indole ring, galanthindole may represent the prototype of a new subgroup of the Amaryllidaceae alkaloids. Two other bases, (+)-11-hydroxyvittatin...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-43206
更新日期:2003-09-01 00:00:00
abstract::The present study was designed to investigate the mechanism of action of n-butylidenephthalide on the deficits of inhibitory avoidance performance induced by drugs in rats with piracetam as a positive control. n-Butylidenephthalide attenuated the scopolamine-induced and mecamylamine-induced acquisition impairment, and...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-10631
更新日期:2001-02-01 00:00:00
abstract::High molecular compounds from Chinese herbal medicines, including ribosome-inactivating proteins and polysaccharides from both fungi and high plants have been tested for the treatment of malignant diseases. Polysaccharides possessing immunostimulating activities can be used as adjuvants in tumor treatment. The fungi c...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-2003-38494
更新日期:2003-03-01 00:00:00
abstract::The major alkaloids of PAPAVER TRINIIFOLIUM collected in two different parts of Anatolia have proved to be of the aporphine, morphinane and rhoeadine types. The two collections possessed different major alkaloids and the existence of chemical strains is indicated. In addition to the aporphine-(floripavidine), the morp...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969808
更新日期:1983-09-01 00:00:00
abstract::A known sesquiterpene lactone, encelin, isolated from the Mexican species Montanoa speciosa (Compositae), was assayed for biocidal activity on fungal cells of Mucor rouxii. The results indicate that encelin has a determining action on growth and the morphogenetic process of fungal cells. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-958046
更新日期:1995-04-01 00:00:00
abstract::The hydroalcoholic extract (HE) obtained from stems and leaves of Hedyosmum brasiliense, given i.p., produced significant inhibition of acetic acid-induced abdominal constriction in mice, with a mean ID50 of 12.7 mg/kg. This effect installed rapidly (0.5 h) and lasted for up to 2 h. Given orally up to 1000 mg/kg, the ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-1999-14007
更新日期:1999-08-01 00:00:00
abstract::Capillary GC, GC-MS, IR, GC-IR, (1)H- and (13)C-NMR studies of the essential oil from the leaves and cones of ELSHOLTZIA POLYSTACHYA collected from two different locations in India revealed that one oil contained 1,8-cineol (37.3%), the other one perillene (61.2%) as the main constituent. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-961490
更新日期:1992-08-01 00:00:00
abstract::Many compounds of plant origin have been identified that inhibit different stages in the replication cycle of human immunodeficiency virus (HIV): 1) virus adsorption: chromone alkaloids (schumannificine), isoquinoline alkaloids (michellamines), sulphated polysaccharides and polyphenolics, flavonoids, coumarins (glycoc...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-2006-957384
更新日期:1998-03-01 00:00:00
abstract::A quantitative analysis using (1)H-NMR (Q-NMR) has been developed for the determination of strychnine and brucine in Strychnos nux-vomica seeds and stems. The advantages of the method are that no reference alkaloids are needed for calibration curves, the quantification could be directly realized on a crude extract, st...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-818014
更新日期:2003-12-01 00:00:00
abstract::Synthetic butylidenephthalide (Bdph), 60 mg/kg per os (p.o.) given 3 h prior to injection of pituitrin (4 U/kg, i.v.), significantly prevented T-wave lowering on lead II electrocardiograph in unanesthetized rats. The effective dose, 60 mg/kg, was about 1/56th of the median lethal dose (LD50, p.o.) in rats. However, Bd...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957415
更新日期:1998-04-01 00:00:00
abstract::The configurations of the component amino acids in ginseng tetrapeptide 1 isolated from Panax ginseng were determined by HPLC with an optical resolution column and the structure of 1 was established to be H-L-Val-gamma-D-Glu-D-Arg- Gly-OH. Synthesis of the ginseng tetrapeptide, 1, and of the configuration and conjugat...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957830
更新日期:1996-04-01 00:00:00
abstract::The medicinal properties of curcumin obtained from Curcuma longa L. cannot be utilised because of poor bioavailability due to its rapid metabolism in the liver and intestinal wall. In this study, the effect of combining piperine, a known inhibitor of hepatic and intestinal glucuronidation, was evaluated on the bioavai...
journal_title:Planta medica
pub_type: 临床试验,杂志文章
doi:10.1055/s-2006-957450
更新日期:1998-05-01 00:00:00
abstract::The antioxidant effects of 1,5-anhydro-D-fructose (1,5-AF), a unique anhydrohexulose, were studied in 1,1-diphenyl-2-picrylhydrazyl (DPPH) solution, in human cells along with lipid peroxidation of low-density lipoprotein (LDL). We have confirmed that 1,5-AF scavenges DPPH radicals directly in solution and inhibits the...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-20050
更新日期:2002-01-01 00:00:00