Three new acylated glycosides from the stems of Casearia velutina and their protective effect against H2O2-induced impairment in PC12 cells.

Abstract:

:Chemical investigation of the stems of Casearia velutina led to the isolation and structural elucidation of three new acylated glycosides, casearicosides A-C (1-3), together with 13 known compounds. The structures of the new compounds were established by spectroscopic and chemical methods. These isolates were evaluated for protective effects against H(2)O(2)-induced impairment in PC12 cells and inhibitory activity against snake venom phosphodiesterase I. A brief chemotaxonomy of the genus Casearia is also discussed.

journal_name

Planta Med

journal_title

Planta medica

authors

Chai XY,Li FF,Bai CC,Xu ZR,Shi HM,Tu PF

doi

10.1055/s-0029-1185902

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

91-3

issue

1

eissn

0032-0943

issn

1439-0221

journal_volume

76

pub_type

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