Eupatoriopicrin 19-O-Linolenoate and Other Constituents from Eupatorium cannabium.

abstract：:We have examined the immunosuppressive effects of representative ginsenosides (Rb1, Rb2, Re and Rg1) from Panax ginseng C. A. Meyer on CD4+ and CD8+ lymphocyte proliferation. Ginsenosides differentially modulated lymphocyte proliferation induced by concanavalin A (Con A), lipopolysaccharide (LPS), phytohemaglutinin (P...

journal_title：Planta medica

authors： Cho JY,Kim AR,Yoo ES,Baik KU,Park MH

更新日期：2002-06-01 00:00:00

abstract：:Olive oil has been shown to exhibit beneficial effects in the prevention of cardiovascular diseases although its molecular mechanism still remains unclear. In the present study, we investigated the effect of hydroxytyrosol (HT), a major phenolic component in olive oil and leaves from OLEA EUROPAEA L. (Oleaceae family...

journal_title：Planta medica

authors： Zrelli H,Matsuka M,Araki M,Zarrouk M,Miyazaki H

更新日期：2011-10-01 00:00:00

abstract：:Hydroalcoholic extracts and pressed juice from Echinacea pallida were phytochemically characterised by HPLC-MS analyses. Ferulic and caffeic acid derivatives were identified as major constituents. All tested extracts and pressed juice from Echinacea pallida exhibited a low cytotoxic activity on monkey kidney cells in ...

journal_title：Planta medica

authors： Schneider S,Reichling J,Stintzing FC,Messerschmidt S,Meyer U,Schnitzler P

更新日期：2010-02-01 00:00:00

abstract：:Extracts from Bupleurum fruticescens were examined for oral and topical anti-inflammatory activities. The BuOH extract proved to be active against carrageenan and tetradecanoylphorbol acetate acute edemas and allowed the isolation of three saponins identified by spectroscopic techniques as 3 beta-O-(O-alpha-L-rhamnopy...

journal_title：Planta medica

authors： Just MJ,Recio MC,Giner RM,Cuéllar MJ,Máñez S,Bilia AR,Ríos JL

更新日期：1998-06-01 00:00:00

abstract：:Some enzymes of the terminal steps of phenylalanine and tyrosine biosyntheses were investigated in various alkaloid-forming ergot strains. All strains studied utilize both arogenate and phenylpyruvate as an intermediate in L-phenylalanine synthesis. L-Tyrosine is preferentially or exclusively synthesized via the aroge...

journal_title：Planta medica

authors： Schmauder HP,Gröger D

更新日期：1986-10-01 00:00:00

abstract：:O-Methyl (1), O-ethyl (2), and O-butyl (3) 4-[(α-L-rhamnosyloxy) benzyl] thiocarbamate (E), along with 4-(α-L-rhamnosyloxy) benzyl isothiocyanate (4) have been isolated from the aerial parts of Moringa peregrina. The compounds were tested for in vitro activity against Trypanosoma brucei rhodesiense and cytotoxicity in...

journal_title：Planta medica

authors： Ayyari M,Salehi P,Ebrahimi SN,Zimmermann S,Portmann L,Krauth-Siegel RL,Kaiser M,Brun R,Rezadoost H,Rezazadeh S,Hamburger M

更新日期：2014-01-01 00:00:00

abstract：:Picroliv, a standardized extract from the plant Picrorhiza kurrooa containing active constituents, showed a significant dose dependent (3-12 mg/kg p.o. x 7) protective activity against galactosamine-induced hepatic damage in rat as evaluated on the isolated hepatocytes (ex vivo) preparation. It markedly increased the ...

journal_title：Planta medica

authors： Visen PK,Shukla B,Patnaik GK,Dhawan BN

更新日期：1993-02-01 00:00:00

abstract：:Both borneol and menthol are bioactive substances derived from Chinese herbal medicines. In order to understand the pharmacokinetics of borneol and menthol in Qingyan drop pills, a rapid, sensitive, and simple gas chromatographic (GC) method with flame ionization detection (FID) was developed for the simultaneous dete...

journal_title：Planta medica

authors： Xu X,Li Y,Hou J,Zhang S,Xu Y,Wang Y,Zhang Y,Liu C,He X

更新日期：2011-09-01 00:00:00

abstract：:The effects of the essential oil of Mentha pulegium L. (EOMP), a plant commonly known as "pennyroyal" or "poejo" that is used in folk medicine as an abortifaceant, were assessed on the isolated rat myometrium. Myometrial strips were stimulated with 10 nM oxytocin or 10 microM PGF (2alpha). EOMP (10 - 300 microg/mL) co...

journal_title：Planta medica

authors： Soares PM,Assreuy AM,Souza EP,Lima RF,Silva TO,Fontenele SR,Criddle DN

更新日期：2005-03-01 00:00:00

abstract：:Eight compounds were isolated from the CH (2)Cl (2) extracts of ERYTHRINA SENEGALENSIS to assess HIV-1 protease (PR) activity inhibition. The prenylated isoflavone structures, identified by spectroscopic analysis, were 8-prenylluteone ( 1), auriculatin ( 2), erysenegalensein O ( 3), erysenegalensein D ( 4), erysenegal...

journal_title：Planta medica

authors： Lee J,Oh WK,Ahn JS,Kim YH,Mbafor JT,Wandji J,Fomum ZT

更新日期：2009-02-01 00:00:00

abstract：:Juniperus (Cupressaceae, Pinales) plants are widely distributed in the Qinghai-Tibet Plateau of China. The leaves and twigs of at least 8 Juniperus species (J. pingii, J. pingii var. wilsonii, J. squamata, J. recurva var. coxii, J. saltuaria, J. indica, J. tibetica and J. convallium var. microsperma) have been used as...

journal_title：Planta medica

authors： Yang YT,De J,Fu ZL,Wang XL,Chen DF,Xie H,Lu Y

更新日期：2020-11-01 00:00:00

abstract：:Five new dibenzocyclooctane lignans, schisanwilsonins K-O, together with eighteen known lignans were isolated from the stems of Schisandra wilsoniana. The structures of these new compounds were elucidated by spectroscopic methods, including 2D-NMR techniques. Several compounds were found to show anti-HIV and anti-HBV ...

journal_title：Planta medica

authors： Ma WH,Lu Y,Chen DF

更新日期：2013-08-01 00:00:00

abstract：:In this study we investigate the active constituents of the rhizome of Zingiber officinale, Roscoe (ginger) and determine their activity on glucose uptake in cultured L6 myotubes and the molecular mechanism underlying this action. Freeze-dried ginger powder was extracted with ethyl acetate (1 kg/3 L) to give the total...

journal_title：Planta medica

authors： Li Y,Tran VH,Duke CC,Roufogalis BD

更新日期：2012-09-01 00:00:00

abstract：:Solasodine--a steroid present in the mucilaginous exotesta of the seed in Solanum viarum Dunal (syn. S. khasianum var. chatterjeeanum) is a major source of steroidal raw material. Evidence for the site of solasodine synthesis was sought through reciprocal grafts involving steroid-bearing S. viarum (both diploid and au...

journal_title：Planta medica

authors： Srinivas M,Krishnan R

更新日期：1996-08-01 00:00:00

abstract：:The antisecretory activity of Guazuma ulmifolia bark was examined in rabbit distal colon mounted in an Ussing chamber. Chloride secretion was stimulated by cholera toxin and prostaglandin E2 (PGE2). Guazuma ulmifolia extract (GUE) completely inhibited cholera toxin-induced secretion if the extract was added to the muc...

journal_title：Planta medica

authors： Hör M,Rimpler H,Heinrich M

更新日期：1995-06-01 00:00:00

abstract：:We have identified kamebakaurin as an inhibitor of NF-KB and elucidated its molecular mechanism as a specific inhibitor in the DNA-binding activity of the p50 subunit of NF-KB. Here, we describe its anti-inflammatory activity in in vitro and in vivo models. Kamebakaurin dose-dependently inhibited not only the expressi...

journal_title：Planta medica

authors： Lee JH,Choi JK,Noh MS,Hwang BY,Hong YS,Lee JJ

更新日期：2004-06-01 00:00:00

abstract：:A phytochemical study of the whole plant of TEPHROSIA HAMILTONII afforded a new flavonoid, characterised as 5, 7-dimethoxy-8-(2, 3-epoxy-3-methylbutyl)-flavanone, along with other known compounds. ...

journal_title：Planta medica

authors： Falak AH,Shoeb A

更新日期：1987-04-01 00:00:00

abstract：:The benzophenanthridine alkaloids sanguinarine and chelerythrine of Chelidonium majus, L. (Papaveraceae), are potent inhibitors of 5-lipoxygenase in polymorphonuclear leukocytes and 12-lipoxygenase in mouse epidermis, while the activity of soybean lipoxygenase is not influenced. The extract of the herb of Ch.majus als...

journal_title：Planta medica

authors： Vavrecková C,Gawlik I,Müller K

更新日期：1996-10-01 00:00:00

abstract：:Dihydrogoniothalamin is a styrylpyrone isolated from the leaves of Aniba panurensis. The present work aimed at investigating the vasorelaxant activity of dihydrogoniothalamin and its underlying mechanism of action in the rat aorta. Dihydrogoniothalamin (0.01-100 µM) induced a concentration-dependent vasodilatation of ...

journal_title：Planta medica

authors： Rezende BA,Silva GC,Corradi RG,Teles MM,Barbosa-Filho JM,Lemos VS,Cortes SF

更新日期：2015-10-01 00:00:00

abstract：:From Polygonum hydropiper L., a C13-norisoprenoid glucoside was isolated and its absolute configuration was established to be (6S,9S)-roseoside (1) by spectroscopic evidence and X-ray crystallographic analysis of its acetate derivative (2). In addition, the stereostructure of roseoside from Canthium subcordatum was re...

journal_title：Planta medica

authors： Murai Y,Kashimura S,Tamezawa S,Hashimoto T,Takaoka S,Asakawa Y,Kiguchi K,Murai F,Tagawa M

更新日期：2001-07-01 00:00:00

abstract：:Pure compounds were isolated from plant extracts with antimalarial activity. The extracts were obtained from the tubers of Cyperus rotundus L. (Cyperaceae), the rootbark of Zanthoxylum gilletii (De Wild) Waterm. (Rutaceae), and the rootbark of Margaritaria discoidea (Baill.) Webster (Euphorbiaceae). The most active co...

journal_title：Planta medica

authors： Weenen H,Nkunya MH,Bray DH,Mwasumbi LB,Kinabo LS,Kilimali VA,Wijnberg JB

更新日期：1990-08-01 00:00:00

abstract：:The aerial parts of Guarea guidonia afforded three new tirucallane-type triterpenoids: 3,4-seco-tirucalla-4(28),8(9),24(25)-trien-7α,11α-dihydroxy-21,23-epoxy-3,11-olide, named guareolide (1: ), 3,4-seco-tirucalla-4(28),7(8),24(25)-trien-21-hydroxy-21,23-epoxy-3-oic acid, named guareoic acid A (2: ), and 3,4-seco-tiru...

journal_title：Planta medica

authors： Hernandez V,De Leo M,Cotugno R,Braca A,De Tommasi N,Severino L

更新日期：2018-07-01 00:00:00

abstract：:Baicalein, berberine, curcumin and hesperidin are the major components derived from Scutellaria baicalensis, Coptis japonica, Curcuma longa and Poncirus trifoliata, respectively. These plants have been used for the treatment of diverse chronic inflammatory diseases including respiratory disease in oriental medicine an...

journal_title：Planta medica

authors： Lee CJ,Lee JH,Seok JH,Hur GM,Park YC,Seol IC,Kim YH

更新日期：2003-06-01 00:00:00

abstract：:A plant mixture containing extracts of Nigella sativa possesses blood glucose lowering effects, but the direct antidiabetic effect of Nigella sativa is not yet established. Therefore, the effect of Nigella sativa oil (NSO) on blood glucose concentrations was studied in streptozotocin diabetic rats. In addition, the ef...

journal_title：Planta medica

authors： El-Dakhakhny M,Mady N,Lembert N,Ammon HP

更新日期：2002-05-01 00:00:00

abstract：:Because Rhodiola plants are known to have a protective effect on diabetic nephropathy, this study aimed to investigate the inhibitory effect of salidroside, the main active component of Rhodiola plants, on high glucose-induced mesangial cell proliferation and its possible mechanism. Salidroside (1 approximately 100 mi...

journal_title：Planta medica

authors： Yin D,Yao W,Chen S,Hu R,Gao X

更新日期：2009-09-01 00:00:00

abstract：:Some diterpenoids show various biological activities, including anti-inflammatory, anti-HIV and anti-tumor activity. Previously, we have focused our research on the apoptosis-inducing properties of diterpenoids and found that some ent-kaurene-type diterpenoids induced apoptosis in human leukemia HL-60 cells. In this s...

journal_title：Planta medica

authors： Kondoh M,Nagashima F,Suzuki I,Harada M,Fujii M,Asakawa Y,Watanabe Y

更新日期：2005-11-01 00:00:00

abstract：:Three compounds with anti-inflammatory activity were isolated from Schinus molle fruits. Two of the compounds were identified as 3- epi-isomasticadienolalic acid ( 1), isomasticadienonalic acid ( 2) and chamaejasmin ( 3). Triterpenes 1 and 2, and biflavanone 3 were tested on two models of mice paw inflammation: one of...

journal_title：Planta medica

authors： Yueqin Z,Recio MC,Máñez S,Giner RM,Cerdá-Nicolás M,Ríos JL

更新日期：2003-10-01 00:00:00

abstract：:The aggregation of the microtubule-associated protein tau is a significant event in many neurodegenerative diseases including Alzheimer's disease. The inhibition or reversal of tau aggregation is therefore a potential therapeutic strategy for these diseases. Fungal natural products have proven to be a rich source of u...

journal_title：Planta medica

authors： Paranjape SR,Chiang YM,Sanchez JF,Entwistle R,Wang CC,Oakley BR,Gamblin TC

更新日期：2014-01-01 00:00:00

abstract：:Ginsenoside Ro, an oleanane-type saponin has been screened for activity in experimental models of acute and chronic hepatitis. Ginsenoside Ro (50 and 200 mg/kg, P.O.) inhibited the increase of serum glutamic oxaloacetic transaminase (s-GOT) and serum glutamic pyruvic transaminase (s-GPT) levels in D-galactosamine (Gal...

journal_title：Planta medica

authors： Matsuda H,Samukawa K,Kubo M

更新日期：1991-12-01 00:00:00

abstract：:Five new xanthone glycosides, comastomasides A-E (1-5), were isolated from aqueous ethanol extracts of the aerial portions of Comastoma pedunculatum. The structures of these compounds were elucidated by spectroscopic analysis methods. Compounds 1-5 were evaluated for their hepatoprotective activity and cytotoxicity ag...

journal_title：Planta medica

authors： Qiao Y,Yuan Y,Cui B,Zhang Y,Chen H,Li S,Li Y

更新日期：2012-09-01 00:00:00