Anti-inflammatory effect of kamebakaurin in in vivo animal models.

abstract：:Lipophilic extracts of Isatis tinctoria L. exhibit significant activity against several clinically relevant targets of inflammation. The alkaloid tryptanthrin was identified as one of the active principles in woad and characterised as a potent dual inhibitor of COX-2 and 5-LOX. Here, the anti-inflammatory efficacy of ...

journal_title：Planta medica

authors： Heinemann C,Schliemann-Willers S,Oberthür C,Hamburger M,Elsner P

更新日期：2004-05-01 00:00:00

abstract：:A phytochemical study of the whole plant of TEPHROSIA HAMILTONII afforded a new flavonoid, characterised as 5, 7-dimethoxy-8-(2, 3-epoxy-3-methylbutyl)-flavanone, along with other known compounds. ...

journal_title：Planta medica

authors： Falak AH,Shoeb A

更新日期：1987-04-01 00:00:00

abstract：:A contribution of the volatile oil from ginger rhizomes (Zingiber officinale Roscoe) on inhabiting the 5-HT3 receptor complex had been shown. In the present study a possible interaction of some compounds of the volatile oil with the 5-HT3 receptor system expressed in N1E-115 cells and with the serotoninergic system of...

journal_title：Planta medica

authors： Riyazi A,Hensel A,Bauer K,Geissler N,Schaaf S,Verspohl EJ

更新日期：2007-04-01 00:00:00

abstract：:From the fresh, undried, and uncrushed leaves of NERIUM OLEANDER a new triterpenoid, kanerocin, has been isolated along with known ursolic and oleanolic acids and its structure established through chemical and spectroscopic methods as 3alpha-hydroxy-urs-18,20-dien-28-oic acid. ...

journal_title：Planta medica

authors： Siddiqui S,Siddiqui BS,Begum S,Hafeez F

更新日期：1989-06-01 00:00:00

abstract：:Positive inotropic effects induced by 6-benzylaminopurine (6-BAP), kinetin and zeatin were studied in rat atria. The potency order observed was 6-BAP > or = kinetin > zeatin. Suramin, a P2-purinoceptor antagonist, inhibited the positive effect of 6-BAP suggesting the involvement of P2-purinoceptors in the positive eff...

journal_title：Planta medica

authors： Froldi G,Gallo U,Ragazzi E,Caparrotta L

更新日期：1999-04-01 00:00:00

abstract：:The effects of phytoestrogens on the female breast are discussed controversially. On the one hand, epidemiological and experimental data provide evidence that dietary phytoestrogens may prevent the development of breast cancer. On the other hand, in breast cancer cell lines and tumour models isoflavone phytoestrogens ...

journal_title：Planta medica

authors： Hertrampf T,Schmidt S,Seibel J,Laudenbach-Leschowsky U,Degen GH,Diel P

更新日期：2006-03-01 00:00:00

abstract：:Plectranthus barbatus Andr. is one of the most important species of the genus Plectranthus L' Herit. (Lamiaceae), with a wide variety of traditional medicinal uses in Hindu and Ayurvedic traditional medicine as well as in the folk medicine of Brazil, tropical Africa and China. The plant has therefore been an attractiv...

journal_title：Planta medica

authors： Alasbahi RH,Melzig MF

更新日期：2010-05-01 00:00:00

abstract：:An in vitro propagation protocol for rapidly producing Hydrastis canadensis L., Goldenseal, plantlets from disk tissue of young leaves was developed. Leaf explants were inoculated on MS medium supplemented with various concentrations of NAA and TDZ for production of callus. Two-month-old calli were sub-cultured on MS ...

journal_title：Planta medica

authors： Bedir E,Lata H,Schaneberg B,Khan IA,Moraes RM

更新日期：2003-01-01 00:00:00

abstract：:The aim of this study was to determine the molecular mechanism underlying the inhibition of vascular restenosis by Radix Sophorae Flavescentis (RSF) extract after balloon dilatation injury. In a rat carotid model of balloon dilatation injury, the RSF extract showed a significant inhibitory effect on vascular restenosi...

journal_title：Planta medica

authors： Long G,Wang G,Ye L,Lin B,Wei D,Liu L,Yang L

更新日期：2009-10-01 00:00:00

abstract：:The involvement of unfolded protein response (UPR) activation in tumor survival and resistance to chemotherapies suggests a new anticancer strategy targeting UPR pathway. Arctigenin, a natural product, has been recently identified for its antitumor activity with selective toxicity against cancer cells under glucose st...

journal_title：Planta medica

authors： Sun S,Wang X,Wang C,Nawaz A,Wei W,Li J,Wang L,Yu DH

更新日期：2011-01-01 00:00:00

abstract：:Esters of 13-hydroxylupanine and 4-hydroxylupanine with acetic, propionic, butyric, isobutyric, valeric, isovaleric, tiglic, benzoic, and TRANS-cinnamic acid have been synthesized and characterized by capillary gas-liquid chromatography and mass spectrometry (EI-MS, CI-MS). In LUPINUS POLYPHYLLUS, L. ALBUS, L. ANGUSTI...

journal_title：Planta medica

authors： Mühlbauer P,Witte L,Wink M

更新日期：1988-06-01 00:00:00

abstract：:A new tetrahydrofuranoketone lignan (1) and two new tetrahydrofuranoketone lignan glycosides (2, 3) were isolated from the ethanol extract of the aerial part of Mananthes patentiflora. The structure elucidations of these compounds were mainly established on the basis of 1D, 2D NMR and HR-mass spectroscopic analysis. A...

journal_title：Planta medica

authors： Tian J,Yang X,Di Y,Ma Y,Li L,Li L,He H,Hao X

更新日期：2009-04-01 00:00:00

abstract：:Activator protein 1 (AP-1) is a transcription factor which plays a critical role in inflammation and carcinogenesis. The present study was conducted to investigate the effect of berberine, an isoquinoline alkaloid present in plants of the genera Berberis and Coptis, on the activity of AP-1 using a reporter gene assay ...

journal_title：Planta medica

authors： Fukuda K,Hibiya Y,Mutoh M,Koshiji M,Akao S,Fujiwara H

更新日期：1999-05-01 00:00:00

abstract：:Protopanaxatriol and protopanaxadiol exhibit limited oral bioavailability due to the poor solubility and intestinal cytochromes P450-mediated metabolism. This study set out to develop a novel cytochromes P450 inhibitory excipient(s)-based self-microemulsion to encapsulate protopanaxatriol and protopanaxadiol so as to ...

journal_title：Planta medica

authors： Yang F,Zhou J,Liu C,Hu X,Pan R,Chang Q,Liu X,Liao Y

更新日期：2017-03-01 00:00:00

abstract：:Eleven sesquiterpenoids have been isolated from the whole plants of Youngia japonica (Asteraceae). Among these sesquiterpenoids, five were identified as new compounds on the basis of spectroscopic methods and chemical analysis. Their structures were 3-oxo-8alpha-(4-hydoxyphenyl)acetoxy-10(14),11(13)-guaiadien-12,6-oli...

journal_title：Planta medica

authors： Chen W,Liu Q,Wang J,Zou J,Meng D,Zuo J,Zhu X,Zhao W

更新日期：2006-02-01 00:00:00

abstract：:A methanol extract of the leaves of Syzygium polyanthum (Wight) Walp. afforded four new acylbenzene derivatives (1-4) together with seven known compounds (5-11). The structures of 1-11 were elucidated by extensive spectroscopic methods and comparison with the literature data. The new compounds 1-3 and a known compound...

journal_title：Planta medica

authors： Saifudin A,Tanaka K,Kadota S,Tezuka Y

更新日期：2012-08-01 00:00:00

abstract：:Three new tetrahydroprotoberberine N-oxide alkaloids, (-)- cis-corydalmine N-oxide, (-)- trans-corydalmine N-oxide, and (-)- trans-isocorypalmine N-oxide, along with three known benzo[ C]phenanthridine alkaloids, norsanguinarine, dihydrosanguinarine, and oxysanguinarine, six known berberine alkaloids, (-)-tetrahydropa...

journal_title：Planta medica

authors： Chen JJ,Duh CY,Chen IS

更新日期：1999-10-01 00:00:00

abstract：:A sensitive and rapid liquid chromatography-mass spectrometric method for the determination of ophiopogonin D in rat plasma was developed and validated. Chromatographic separation was performed on a C (18) column using a step gradient program with the mobile phase of 0.5 mmol/L ammonium chloride solution and acetonitr...

journal_title：Planta medica

authors： Xia CH,Sun JG,Hao HP,Wang GJ,Yan B,Gu SH,Zheng CN,Shang LL,Roberts MS

更新日期：2008-12-01 00:00:00

abstract：:Nano-encapsulation of several natural products has become an important tool in enhancing the bioavailability of some modern drugs against many diseases. Pelargonidin is an anthocyanidin found in many fruits and vegetables. Pelargonidin is loaded with poly-lactide-co-glycolic-acid, a non-toxic biodegradable polymer, to...

journal_title：Planta medica

authors： Samadder A,Tarafdar D,Abraham SK,Ghosh K,Khuda-Bukhsh AR

更新日期：2017-03-01 00:00:00

abstract：:We previously reported that total coumarins, the major active components of Urtica dentata Hand, exhibited substantial protection against the development of autoimmune diabetes. Diabetic nephropathy is one of the most serious complications of diabetes and is closely correlated with end-stage renal disease. We used the...

journal_title：Planta medica

authors： Cao H,Ji Y,Li W,Liu Y,Fu R,Xiang M

更新日期：2015-10-01 00:00:00

abstract：:The activity-guided fractionation of the extract of the root of Salvia miltiorrhiza B. (Labiatae, Tanshen), led to the isolation of four active components responsible for the anti-allergic activity in vitro. Among them, 15,16-dihydrotanshinone-I and cryptotanshinone demonstrated significant inhibition of the release o...

journal_title：Planta medica

authors： Ryu SY,Oak MH,Kim KM

更新日期：1999-10-01 00:00:00

abstract：:Enzymatic thrombin activity is significantly inhibited only by a few selected natural phenolic compounds (myricetin, rosmarinic acid, caffeic acid phenethyl ester) but more strongly by unsaturated fatty acids like erucic acid and oleic acids. Compared to the inhibitory potential against neutrophil elastase, thrombin a...

journal_title：Planta medica

authors： Melzig MF,Henke K

更新日期：2005-08-01 00:00:00

abstract：:Volatile oils of the leaves, fruits and stem-bark of CLEISTOPHOLIS PATENTS Engl. et Diels. (Annonacae) were analysed by means of gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of sixty-one components were identified; qualitative and quantitative differences in the oil composition wer...

journal_title：Planta medica

authors： Ekundayo O,Laakso I,Oguntimein B,Hiltunen R

更新日期：1988-08-01 00:00:00

abstract：:Plumbagin, an active principle from Plumbaginaceous plants, produced a triphasic inotropic response (first positive, second negative, and third positive phases) in guinea-pig papillary muscle. The inotropic potency of plumbagin at the first positive phase was pD2 6.40, and the methylation of 5-hydroxy group of plumbag...

journal_title：Planta medica

authors： Itoigawa M,Takeya K,Furukawa H

更新日期：1991-08-01 00:00:00

abstract：:The roots of HAPLOPAPPUS FREEMONTII afforded in addition to the known 8-oxo-beta-cyperone two further derivatives. The structures were elucidated by highfield (1)H-NMR spectroscopy. ...

journal_title：Planta medica

authors： Jakupovic J,Boeker R,King RM

更新日期：1986-10-01 00:00:00

abstract：:Two phenolic triterpenoids, pristimerol (30 µg/mL) and 8- EPI-6-deoxoblepharodol (20 µg/mL), obtained by catalytic reduction of pristimerin, exhibited bacteriostatic action against Staphylococcus epidermidis. This activity was not dependent on the inoculum size and the growth phase although it showed a stronger effect...

journal_title：Planta medica

authors： López MR,de León L,Moujir L

更新日期：2011-05-01 00:00:00

abstract：:Six new pyrrolizidine alkaloids, a new carboxylic acid, a new phenolic and a new oleanane glycoside, together with the known compounds 7,7'-bis-(4-hydroxy-3,5-dimethoxyphenyl)-8,8'-dihydroxymethyltetrahydrofuran 4'-O-beta-D-glucopyranoside, rosmarinic acid, caffeic acid, tormentic acid 28-O-beta- D-glucopyranoside, eu...

journal_title：Planta medica

authors： Braca A,Bader A,Siciliano T,Morelli I,De Tommasi N

更新日期：2003-09-01 00:00:00

abstract：:Novel therapies are needed to address the public health problem posed by methicillin-resistant STAPHYLOCOCCUS AUREUS (MRSA). In this study, we determined the effects of combinations of antibiotics and plant polyphenols against 20 clinical isolates of MRSA. The IN VITRO activities of 10 antibiotics and 15 natural polyp...

journal_title：Planta medica

authors： Lin RD,Chin YP,Hou WC,Lee MH

更新日期：2008-06-01 00:00:00

abstract：:From the bark of Sclerocarya birrea was isolated (-)-epicatechin-3-galloyl ester of which the structure was elucidated by NMR spectroscopy. The compound has secretagogue activity. ...

journal_title：Planta medica

authors： Galvez Peralta J,Zarzuelo A,Busson R,Cobbaert C,de Witte P

更新日期：1992-04-01 00:00:00

abstract：:Six new triterpenoids including four new secodammarane triterpenoid glycosides (1-4), an epoxydammarane triterpenoid glycoside (5), and a new secodammarane triterpenoid (6) were isolated from the ethanolic extract of the leaves of Cyclocarya paliurus. The structures of these compounds were elucidated by spectroscopic ...

journal_title：Planta medica

authors： Li S,Cui B,Liu Q,Tang L,Yang Y,Jin X,Shen Z

更新日期：2012-02-01 00:00:00