New xanthone glycosides from Comastoma pedunculatum.

Abstract:

:Five new xanthone glycosides, comastomasides A-E (1-5), were isolated from aqueous ethanol extracts of the aerial portions of Comastoma pedunculatum. The structures of these compounds were elucidated by spectroscopic analysis methods. Compounds 1-5 were evaluated for their hepatoprotective activity and cytotoxicity against four human cancer cell lines by in vitro assays. Among them, compounds 3 and 5 exhibited potent hepatoprotective activity. However, none of the compounds displayed cytotoxic activity.

journal_name

Planta Med

journal_title

Planta medica

authors

Qiao Y,Yuan Y,Cui B,Zhang Y,Chen H,Li S,Li Y

doi

10.1055/s-0032-1315079

subject

Has Abstract

pub_date

2012-09-01 00:00:00

pages

1591-6

issue

14

eissn

0032-0943

issn

1439-0221

journal_volume

78

pub_type

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