Abstract:
:Five new xanthone glycosides, comastomasides A-E (1-5), were isolated from aqueous ethanol extracts of the aerial portions of Comastoma pedunculatum. The structures of these compounds were elucidated by spectroscopic analysis methods. Compounds 1-5 were evaluated for their hepatoprotective activity and cytotoxicity against four human cancer cell lines by in vitro assays. Among them, compounds 3 and 5 exhibited potent hepatoprotective activity. However, none of the compounds displayed cytotoxic activity.
journal_name
Planta Medjournal_title
Planta medicaauthors
Qiao Y,Yuan Y,Cui B,Zhang Y,Chen H,Li S,Li Ydoi
10.1055/s-0032-1315079subject
Has Abstractpub_date
2012-09-01 00:00:00pages
1591-6issue
14eissn
0032-0943issn
1439-0221journal_volume
78pub_type
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