Oligostilbenes from the roots of Vitis thunbergii.

abstract：:Usnic acid, a lichen secondary metabolite produced by a whole number of lichens, has attracted the interest of researchers owing to its broad range of biological activity, including antiviral, antibiotic, anticancer properties, and it possessing a certain toxicity. The synthesis of new usnic acid derivatives and the i...

journal_title：Planta medica

authors： Dyrkheeva N,Luzina O,Filimonov A,Zakharova O,Ilina E,Zakharenko A,Kuprushkin M,Nilov D,Gushchina I,Švedas V,Salakhutdinov N,Lavrik O

更新日期：2019-01-01 00:00:00

abstract：:Bioassay-guided fractionation of the H(2)O extract of the seeds of Psoralea corylifolia furnished one hepatoprotective compound, bakuchiol (1), together with two moderately active compounds, bakuchicin (2) and psoralen (3), on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells. The EC(50) values of compo...

journal_title：Planta medica

authors： Cho H,Jun JY,Song EK,Kang KH,Baek HY,Ko YS,Kim YC

更新日期：2001-11-01 00:00:00

abstract：:From the essential oil of Commiphora guidotti seven sesquiterpene hydrocarbons and a furanosesquiterpenoid, furanodiene, were isolated. ...

journal_title：Planta medica

authors： Craveiro A,Corsano S,Proietti G,Strappaghetti G

更新日期：1983-06-01 00:00:00

abstract：:From the bulbs of Vietnamese Hippeastrum equestre Herb. (Amaryllidaceae), besides the well known alkaloids lycorine, tazettine, and hippeastrine, a new alkaloid, phamine, has been isolated. Its structure was established by spectroscopic methods. ...

journal_title：Planta medica

authors： Döpke W,Pham LH,Gründemann E,Bartoszek M,Flatau S

更新日期：1995-12-01 00:00:00

abstract：:Hepatocellular carcinoma is one of the leading causes of malignancy-related death in China. Its therapy in clinics is a big challenge. Ginsenoside Rh2 is one of the most notable cancer-preventing components from red ginseng and it has been reported that ginsenoside Rh2 exhibited potent cytotoxicity against human hepat...

journal_title：Planta medica

authors： Lv Q,Rong N,Liu LJ,Xu XL,Liu JT,Jin FX,Wang CM

更新日期：2016-05-01 00:00:00

abstract：:Based on rDNA ITS sequences of D. officinale and the other 37 species of Dendrobium, a pair of allele-specific diagnostic primers, TP-JB01S and TP-JB01X, were designed to authenticate D. officinale from the other species. Before the diagnostic PCR, the primer pair, P1 and P2, for amplifying the whole ITS region was us...

journal_title：Planta medica

authors： Ding X,Wang Z,Zhou K,Xu L,Xu H,Wang Y

更新日期：2003-06-01 00:00:00

abstract：:A reinvestigation of the rhizomes of ATRACTYLIS KOREANA afforded in addition to 1,3-diacetoxytetradeca-6,12-diene-8,10-diyne reported previously (1) two new C (14)-polyacetylenes with an ene-diyn-ene-chromophor and one new C (14)-polyacetylene beside two known compounds with an ene-diyne-diene-chromophor. Their struct...

journal_title：Planta medica

authors： Pachaly P,Lansing A,Neugebauer M,Sin KS

更新日期：1990-10-01 00:00:00

abstract：:Phytoestrogens are discussed as candidate substances to treat symptoms related to estrogen deficiency. In in vitro experiments, the naturally occurring flavonoid 6-(1,1-dimethylallyl)naringenin (6-DMAN) emerged as one of the most potent phytoestrogenic substances. 6-DMAN is not as well characterized as other flavonoid...

journal_title：Planta medica

authors： Zierau O,Geis RB,Tischer S,Schwab P,Metz P,Vollmer G

更新日期：2004-07-01 00:00:00

abstract：:From the methanolic extract of the whole plants of Bidens pilosa the new beta-D-glucopyranosyloxy-3-hydroxy-6(E)-tetradecen-8, 10,12-triyne besides a known polyine has been isolated and identified mainly by IR and NMR methods. The new compound showed overgrowing action against normal and transformed human cell lines i...

journal_title：Planta medica

authors： Alvarez L,Marquina S,Villarreal ML,Alonso D,Aranda E,Delgado G

更新日期：1996-08-01 00:00:00

abstract：:The oligomeric stilbenes (+)-alpha-viniferin (1), miyabenol C (2), and kobophenol A (3) have been isolated from Caragana sinica (Buchoz) Rehd (Leguminosae). (+)-alpha-Viniferin (1) and miyabenol C (2) exhibited protein kinase C inhibitory activity at low micromolar concentrations. (+)-alpha-Viniferin inhibited keratin...

journal_title：Planta medica

authors： Kulanthaivel P,Janzen WP,Ballas LM,Jiang JB,Hu CQ,Darges JW,Seldin JC,Cofield DJ,Adams LM

更新日期：1995-02-01 00:00:00

abstract：:Since the beginning of this century, Goji berries and juice are being sold as health food products in western countries and praised in advertisements and in the media for well-being and as an anti-aging remedy. The popularity of Goji products has rapidly grown over the last years thanks to efficient marketing strategi...

journal_title：Planta medica

authors： Potterat O

更新日期：2010-01-01 00:00:00

abstract：:The evidence for loss of Ca2+ homeostasis due to neuronal degeneration is considerable and rapidly increasing. In this study, we try to evaluate the protective effect of tetrandrine (TET), an alkaloid isolated from the Chinese medicinal herb Radix Stephania tetrandrae S., on amyloid-beta protein (Abeta) and 1-methyl-4...

journal_title：Planta medica

authors： Chiou WF,Lee WS,Yeh PH

更新日期：2006-11-01 00:00:00

abstract：:Three new glycosides, 1,4,8-trihydroxynaphthalene-1-O-D-glucopyranosyl-(1-->6)-beta-D- xylopyranoside (1), 1,4,8-trihydroxynaphthalene-1-O-beta-D-glucopyranosyl-(1-->6)-alph a-L- arabinopyranoside (2), 1-hydroxy-4-methoxynaphthalene-1-O-beta-D-glucopyranosyl-(1-->6)- alpha-L-rhamnopyranoside (3), were isolated from th...

journal_title：Planta medica

authors： Lee SW,Lee KS,Son JK

更新日期：2000-03-01 00:00:00

abstract：:The antihyperglycemic action of andrographolide, an active principle in the leaves of Andrographis paniculata (Burm. f.) Nees, was investigated in streptozotocin-induced diabetic rats (STZ-diabetic rats). Oral treatment of andrographolide decreased the plasma glucose concentrations of STZ-diabetic rats in a dose-depen...

journal_title：Planta medica

authors： Yu BC,Hung CR,Chen WC,Cheng JT

更新日期：2003-12-01 00:00:00

abstract：:Increased osteoclastic bone resorption plays a central role in the pathogenesis of many bone diseases. Ganoderma lucidum is known for medicinal effects such as anti-inflammatory and anti-bone resorption activities. In this study, we investigated the inhibitory effects of ganoderic acids isolated from G. lucidum on ost...

journal_title：Planta medica

authors： Liu J,Shiono J,Shimizu K,Kondo R

更新日期：2010-02-01 00:00:00

abstract：:This study aimed to elucidate the mechanisms of nuciferine (a main aporphine alkaloid of lotus leaf extract), which can induce relaxation in contracted tracheal rings. Under Ca2+-free and 2 mM Ca2+ conditions, we found that nuciferine had no effect on the resting muscle tone of tracheal rings. In contrast, nuciferine ...

journal_title：Planta medica

authors： Yang X,Yu MF,Lei J,Peng YB,Zhao P,Xue L,Chen W,Ma LQ,Liu QH,Shen J

更新日期：2018-01-01 00:00:00

abstract：:The therapy of type-2 diabetes mellitus is one of the major challenges of our age. A possible strategy to prevent the progression of this disease is the inhibition of protein tyrosine phosphatase 1B (PTP1B), a major negative regulator in the insulin and leptin signalling pathway. Phellodendri amurensis cortex is a wel...

journal_title：Planta medica

authors： Steinmann D,Baumgartner RR,Heiss EH,Bartenstein S,Atanasov AG,Dirsch VM,Ganzera M,Stuppner H

更新日期：2012-02-01 00:00:00

abstract：:Qianhu, the dried roots of Peucedanum praeruptorum, is a well-known traditional Chinese medicinal herb which was officially listed in the Chinese Pharmacopoeia. Praeruptorin A is the major active constituent of Qianhu. Our previous studies show that praeruptorin effectively transactivated the protein expression and ca...

journal_title：Planta medica

authors： Huang L,Bi HC,Li YH,Zhang JQ,Kuang SY,Zhang L,Wang YT,Huang M

更新日期：2013-11-01 00:00:00

abstract：:Ischemic preconditioning, which is mediated by cell signaling molecules, protects the heart from ischemia-reperfusion injury by limiting the infarct size. Oleuropein, the main polyphenolic constituent of olives, reduced the infarct size in normal and cholesterol-fed rabbits when it was administered at a nutritional do...

journal_title：Planta medica

authors： Andreadou I,Benaki D,Efentakis P,Bibli SI,Milioni AI,Papachristodoulou A,Zoga A,Skaltsounis AL,Mikros E,Iliodromitis EK

更新日期：2015-06-01 00:00:00

abstract：:Many compounds of plant origin have been identified that inhibit different stages in the replication cycle of human immunodeficiency virus (HIV): 1) virus adsorption: chromone alkaloids (schumannificine), isoquinoline alkaloids (michellamines), sulphated polysaccharides and polyphenolics, flavonoids, coumarins (glycoc...

journal_title：Planta medica

authors： Vlietinck AJ,De Bruyne T,Apers S,Pieters LA

更新日期：1998-03-01 00:00:00

abstract：:A microdilution technique was developed for the assessment of in vitro cytotoxicity against KB cells derived from a human epidermoid carcinoma of the nasopharynx. The test was used to determine the cytotoxicity of a series of quassinoids, isolated from Brucea javanica, and which have previously been shown to demonstra...

journal_title：Planta medica

authors： Anderson MM,O'Neill MJ,Phillipson JD,Warhurst DC

更新日期：1991-02-01 00:00:00

abstract：:VERATRUM CALIFORNICUM (Liliaceae) is an important monocotyledonous medicinal plant which is the only source of the anticancer compound cyclopamine. An IN VITRO culture system for somatic embryogenesis and green plant regeneration of VERATRUM CALIFORNICUM was developed. Embryogenic calli were induced from mature embryo...

journal_title：Planta medica

authors： Ma R,Ritala A,Oksman-Caldentey KM,Rischer H

更新日期：2006-10-01 00:00:00

abstract：:From roots of Rubia cordifolia L. four anthraquinones are isolated: 1-hydroxy 2-methoxy anthraquinone; 1,4-dihydroxy 2-methyl 5-methoxy anthraquinone or 1,4-dihydroxy 2-methyl 8-methoxy anthraquinone; 1,3-dimethoxy 2-carboxy anthraquinone and rubiadin. ...

journal_title：Planta medica

authors： Dosseh C,Tessier AM,Delaveau P

更新日期：1981-12-01 00:00:00

abstract：:We report a sensitive method for the estimation of quinine (Qn), cinchonine (Cn), and cinchonidine (Cnd) and a new method based on fluorescence enhancement and detection and quantification of quinidine (Qnd) from Cinchona stem bark and its formulations, using HPTLC. Standard solutions of Qn, Qnd, Cn, and Cnd were appl...

journal_title：Planta medica

authors： Ravishankara MN,Shrivastava N,Padh H,Rajani M

更新日期：2001-04-01 00:00:00

abstract：:Flavonoids are metabolized in vivo to monocyclic phenolic acids. We investigated whether 18 phenolic acids of the benzoic, phenylacetic, phenylpropanoic or cinnamic series-known or potential metabolites of flavonoids-inhibit reactive oxygen species (ROS) released by human polymorphonuclear neutrophils (PMNs). Chemilum...

journal_title：Planta medica

authors： Limasset B,Ojasoo T,le Doucen C,Doré JC

更新日期：1999-02-01 00:00:00

abstract：:Four p-terphenyl derivatives named curtisians I-L (1-4) were isolated from the MeOH extract of the fruit bodies of Paxillus curtisii. Their structures were elucidated by 2D NMR, MS, IR and UV spectroscopy and chemical reaction. The absolute configurations of curtisians were determined by GC-MS on a chiral column of th...

journal_title：Planta medica

authors： Quang DN,Hashimoto T,Nukada M,Yamamoto I,Tanaka M,Asakawa Y

更新日期：2003-11-01 00:00:00

abstract：:Five known abietane diterpenes, fatty acid esters of 7alpha-acyloxy-6beta-hydroxyroyleanone (1), grandidone A (2), 7alpha-acetoxy-6beta-hydroxyroyleanone (3), 6beta,7alpha-dihydroxyroyleanone (4), and coleon U (5), isolated from Plectranthus grandidentatus Gürke, were evaluated for their in vitro antiproliferative act...

journal_title：Planta medica

authors： Marques CG,Pedro M,Simões MF,Nascimento MS,Pinto MM,Rodríguez B

更新日期：2002-09-01 00:00:00

abstract：:The hypoglycemic activity of olive leaf was studied. Maximum hypoglycemic activity was obtained from samples collected in the winter months, especially in February. One of the compounds responsible for this activity was oleuropeoside, which showed activity at a dose of 16 mg/kg. This compound also demonstrated antidia...

journal_title：Planta medica

authors： Gonzalez M,Zarzuelo A,Gamez MJ,Utrilla MP,Jimenez J,Osuna I

更新日期：1992-12-01 00:00:00

abstract：:The new I-3', II-3, 3', II-4', I-5, II-5, I-7, II-7-octahydroxy-I-4'-methoxy-I-3, II-8-biflavanone together with known biflavanones GB-1 and GB-2 were isolated from the bark of GARCINIA KOLA. ...

journal_title：Planta medica

authors： Kabangu K,Galeffi C,Aonzo E,Nicoletti M,Messana I

更新日期：1987-06-01 00:00:00

abstract：:EGFR, as a critical signaling pathway in many human tumors, has become an important target of cancer drug design. Taspine has shown meaningful angiogenesis activity in previous studies. This paper is to investigate the antitumor action of taspine by modulating the EGFR signaling pathway. The study determined the expre...

journal_title：Planta medica

authors： Zhang Y,Zheng L,Zhang J,Dai B,Wang N,Chen Y,He L

更新日期：2011-11-01 00:00:00