Abstract:
:Increased osteoclastic bone resorption plays a central role in the pathogenesis of many bone diseases. Ganoderma lucidum is known for medicinal effects such as anti-inflammatory and anti-bone resorption activities. In this study, we investigated the inhibitory effects of ganoderic acids isolated from G. lucidum on osteoclastic differentiation using RAW264 cells in vitro. A carbonyl in C7 is essential to elicit the inhibition of osteoclast differentiation.
journal_name
Planta Medjournal_title
Planta medicaauthors
Liu J,Shiono J,Shimizu K,Kondo Rdoi
10.1055/s-0029-1186035subject
Has Abstractpub_date
2010-02-01 00:00:00pages
137-9issue
2eissn
0032-0943issn
1439-0221journal_volume
76pub_type
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