Abstract:
:The structure of albifloranine 1, a new alkaloid of ibogane type from the stem bark of Tabernaemontana albiflora (M IQ.) Pull. (Apocynaceae) has been determined. A detailed (1)H NMR study of albifloranine 1, coronaridine 2 and heyneanine 3 is presented.
journal_name
Planta Medjournal_title
Planta medicaauthors
Kan C,Husson HP,Kan SK,Lounasmaa Mdoi
10.1055/s-2007-971678subject
Has Abstractpub_date
1981-01-01 00:00:00pages
72-4issue
1eissn
0032-0943issn
1439-0221journal_volume
41pub_type
杂志文章相关文献
PLANTA MEDICA文献大全abstract::The present study is aimed at evaluating the effects of luteolin on the scratching behavior associated with an allergic cutaneous reaction in mice. Elicitation of passive cutaneous anaphylaxis, and intradermal injections of compound 48/80, histamine or serotonin induced scratching behavior in ICR mice. Models of irrit...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-864137
更新日期:2005-05-01 00:00:00
abstract::The pharmacokinetic profile of arctiin, the major active lignan in fruits of Arctium lappa L., was investigated. Its main meta"bolite arctigenin was identified by an LC-MS method, and an HPLC-UV technique was developed for the simultaneous quantification of the metabolite and arctiin in plasma and organs. Chromatograp...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0031-1298433
更新日期:2012-05-01 00:00:00
abstract::Herbal medicine has been used to treat diseases for centuries; however, the biological active components and the mechanistic understanding of actions of plant-derived drugs are permanently discussed. MicroRNAs are a class of small, non-coding RNAs that play crucial roles as regulators of gene expression. In recent yea...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-0042-108450
更新日期:2016-08-01 00:00:00
abstract::In addition to 7-methoxy-2-methyl-3,4,5-trihydroxyanthraquinone (1), physcion (2), macrosporin (3), deoxybostrycin (4), altersolanol B (5) and dactylariol (6), a new hexahydroanthraquinone named pleospdione (7) was isolated from the culture of Pleospora sp . IFB-E006, an endophytic fungus residing in the normal stem o...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-864190
更新日期:2005-11-01 00:00:00
abstract::The crude ethanol extract from the leaves of Dendropanax arboreus (Araliaceae) from Monteverde, Costa Rica, exhibits cytotoxic activity against Hep-G2, A-431, H-4IIE, and L-1210 tumor cell lines, but is not toxic against normal hepatocytes. The active component has been isolated by activity-directed separation and ide...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-958139
更新日期:1995-10-01 00:00:00
abstract::The dichloromethane-soluble fraction of the methanol extract of the stem bark of Millettia versicolor Welw. (Leguminosae) has been shown to possess anti-inflammatory activity. The chromatographic fractionation and subsequent analysis of the spectroscopic data of this extract led to the isolation and identification of ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-42794
更新日期:2003-08-01 00:00:00
abstract::This perspective describes some commonly used animal models for the evaluation of potential chemopreventive agents in colon carcinogenesis. Special emphasis is given to the azoxymethane (AOM)/1,2-dimethylhydrazine (DMH) rat model and APCMIN mice, carrying a mutation in APC, a key gene in human carcinogenesis. In the A...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1074577
更新日期:2008-10-01 00:00:00
abstract::Emodin, chrysophanol and physcion have been shown to be the major anthraquinone pigments present in the dry roots of RUMEX ABYSINICA. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969640
更新日期:1984-02-01 00:00:00
abstract::Plectranthus barbatus Andr. is one of the most important species of the genus Plectranthus L' Herit. (Lamiaceae), with a wide variety of traditional medicinal uses in Hindu and Ayurvedic traditional medicine as well as in the folk medicine of Brazil, tropical Africa and China. The plant has therefore been an attractiv...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-0029-1240898
更新日期:2010-05-01 00:00:00
abstract::In this study, hemolysis, Western blot, and real-time RT-PCR assays were performed to evaluate silibinin's activity against S. aureus α-toxin secretion. In addition, live/dead cell staining and lactate dehydrogenase activity assays were introduced to examine the influence of silibinin on α-toxin-induced cell injury in...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1328068
更新日期:2013-01-01 00:00:00
abstract::The natural compound tyropeptin A, a new peptidyl aldehyde proteasome inhibitor, was tested for its trypanocidal activity in vitro using culture-adapted bloodstream forms of Trypanosoma brucei. The concentrations of tyropeptin A required to reduce the growth rate by 50 % and to kill all cells were 10 and 100 times low...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-931600
更新日期:2006-06-01 00:00:00
abstract::Thirty-five flavonoids of seven different types, namely isoflavonoids, chalcones, dihydroflavonols, flavanols, flavanones, flavones, and flavonols were investigated for their ability to inhibit ascorbate-induced microsomal lipid peroxidation and their cytotoxicity. For each activity a structure-activity relationship w...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-16472
更新日期:2001-08-01 00:00:00
abstract::Seven new clerodane diterpenoids, dysoxydensins A-G (1-7), together with six known clerodanes, were isolated from Dysoxylum densiflorum. The structures of all the compounds were elucidated by extensive spectroscopic analysis. These compounds were evaluated for their cytotoxic activities against five human cancer cell ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0034-1382903
更新日期:2014-08-01 00:00:00
abstract::(1)H- and (13)C-NMR spectral data are presented for six p-terphenylquinone derivatives (and for two monosubstituted quinones 1 and 2, used as model compounds) and for 9,10-phenanthraquinone and retenequinone. The chemical shifts were confirmed through correlation spectroscopy and NOE measurements. ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-957712
更新日期:1997-08-01 00:00:00
abstract::Examined in vitro were the effects of some triterpenoids from Panax (Araliaceae) and Glycyrrhiza (Leguminosae) spp. on the sensitivity to daunomycin (DAU) and vinblastine (VBL) of adriamycin (ADM)-resistant P388 leukemia cells (P388/ADM), which were resistant to multiple anticancer drugs. Quasipanaxatriol, 20(S)-proto...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-958126
更新日期:1995-10-01 00:00:00
abstract::Ten new polyhydroxyolean-12-ene pentacyclic triterpenoidal saponins, named rogchaponins 1-10, were isolated from the methanolic extract of the roots of Camellia sinensis by a series of chromatographic methods (silica gel flash column and C18 MPLC followed by C18 HPLC). Their structures were established by 1D and 2D-NM...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0031-1280024
更新日期:2011-12-01 00:00:00
abstract::The roots of Cryptolepis sanguinolenta have been investigated for their chemical composition since 1931 but so far no studies on the leaves have been reported although they are used in traditional medicine in Guinea-Bissau. Two new alkaloids identified as cryptolepinoic acid (1) and methyl cryptolepinoate (2) and the ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2000-11106
更新日期:2000-02-01 00:00:00
abstract::Because Rhodiola plants are known to have a protective effect on diabetic nephropathy, this study aimed to investigate the inhibitory effect of salidroside, the main active component of Rhodiola plants, on high glucose-induced mesangial cell proliferation and its possible mechanism. Salidroside (1 approximately 100 mi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185717
更新日期:2009-09-01 00:00:00
abstract::An analytical method using HPLC with UV detection was developed to investigate the quassinoid content of Eurycoma longifolia Jack (Simaroubaceae) collected from various sources. Eurycomanone (1), longilactone (2), 14,15beta-dihydroxyklaineanone (3), 15beta-acetyl-14-hydroxyklaineanone (4), 6alpha-hydroxyeurycomalacton...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957570
更新日期:1998-12-01 00:00:00
abstract::Accumulation of furanic labdane diterpenes has been investigated in different parts of field-grown plants of MARRUBIUM VULGARE (Lamiaceae) and LEONURUS CARDIACA (Lamiaceae). Furanic labdane diterpenes were produced and accumulated only in the aerial parts. Greatest amounts were measured in leaves and flowers. Up to 4 ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957451
更新日期:1998-05-01 00:00:00
abstract::The aerial parts of JUNGIA SETERIANA afforded in addition to known compounds two pairs of isomeric C (17)-acetylenes which differ in the number of triple bonds and in the configuration of the 9,10-double bond. The structures and configurations followed from the UV and the (1)H-NMR spectra, especially from those of the...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969670
更新日期:1984-04-01 00:00:00
abstract::We previously reported the isolation of eleven new cardiac glycosides called cheiranthosides I-XI together with two known ones (olitoriside and erysimoside) from the seeds of Erysimum cheiranthoides L. The glycosides were evaluated for their inhibitory activity against Na+,K(+)-ATPase by comparing with typical cardiac...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-14309
更新日期:2001-06-01 00:00:00
abstract::An allergenic protein from tatary buckwheat seeds, designated TBt, was purified by salting out, anion exchange chromatography and size exclusion chromatography (SEC). Analysis by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and SEC showed that the allergenic protein was composed of two subunits...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0028-1088319
更新日期:2008-12-01 00:00:00
abstract::One hundred and thirty-eight medicinal herbal drugs obtained from different suppliers were examined for microbial contaminants and for the detectability of pathogenic microorganisms. For this purpose, several microbiological standard parameters (total aerobic mesophilic count, enterobacteria, coliforms, aerobic sporef...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-12007
更新日期:2001-04-01 00:00:00
abstract::The cytotoxicity of goniothalamin was found to be strong towards both cancerous (HGC-27, MCF-7, PANC-1, HeLa), and non-cancerous (3T3) cell lines, especially in cases of dividing cells. Drug exposure studies indicated that the cytotoxic action of goniothalamin was time- and dose-dependent. At the ultrastructural level...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957611
更新日期:1997-02-01 00:00:00
abstract::Fresh Nagami kumquats (Fortunella margarita) were subjected to hydrodistillation using a Clevenger-type apparatus to obtain volatile oil. The chemical composition of the volatile oil was analyzed by GC-MS using Rtx-5 Sil MS and DB Wax columns. A total of 25 volatile compounds were identified by mass spectra, retention...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0031-1298619
更新日期:2012-06-01 00:00:00
abstract::Solasodine--a steroid present in the mucilaginous exotesta of the seed in Solanum viarum Dunal (syn. S. khasianum var. chatterjeeanum) is a major source of steroidal raw material. Evidence for the site of solasodine synthesis was sought through reciprocal grafts involving steroid-bearing S. viarum (both diploid and au...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957905
更新日期:1996-08-01 00:00:00
abstract::For quantitative determination of grayanotoxin I (1) in plant material, a GC/MS method was developed after trimethylsilyl derivatisation of the analytes. Forskolin (5) was used as an internal standard for quantification. ICH-compliant method validation indicated sufficient specificity, precision, quantitation (15 µg/m...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0034-1383039
更新日期:2014-10-01 00:00:00
abstract::The aim of this study was to investigate the effect of demethylbellidifolin (DMB), a major xanthone compound of Swertia davidi franch, on nitroglycerin (NTG) tolerance. In the in vivo portion of the study, pretreatment of Sprague-Dawley rats with NTG (10 mg/kg) for 8 days caused tolerance to the depressor effect of NT...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185774
更新日期:2009-11-01 00:00:00
abstract::The medicinal plants, Coutarea latiflora Sesse & Moc. ex. DC. (Hintonia latiflora Bullock) (Rubiaceae) and Exostema caribaeum (Jacq.) Roem. et Schult. (Rubiaceae) were examined for antimalarial properties. Among different crude solvent extracts of the stem bark, the hydrolysed ethyl acetate extracts were shown to have...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960885
更新日期:1990-02-01 00:00:00