Abstract:
:Three new xanthones, 22,23-dihydroxydihydrogambogenic acid (1), 12-hydroxygambogefic acid A (2), and hanburixanthone (3), along with thirteen known compounds were isolated from the resin of Garcinia hanburyi. The structures of the new compounds were determined by detailed analysis of 1D and 2D NMR spectra and by comparison with related model compounds. All compounds were tested for their cytotoxicities against A549, HCT116, and MDA-MB-231, and most of them showed significant effects on the cell lines.
journal_name
Planta Medjournal_title
Planta medicaauthors
Deng YX,Guo T,Shao ZY,Xie H,Pan SLdoi
10.1055/s-0032-1328537subject
Has Abstractpub_date
2013-06-01 00:00:00pages
792-6issue
9eissn
0032-0943issn
1439-0221journal_volume
79pub_type
杂志文章相关文献
PLANTA MEDICA文献大全abstract::Plant volatile organic compounds (volatiles) are secondary plant metabolites that play crucial roles in the reproduction, defence, and interactions with other vegetation. They have been shown to exhibit a broad range of biological properties and have been investigated for antimicrobial and anticancer activities. In ad...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1289-4505
更新日期:2020-11-11 00:00:00
abstract::We aimed to find antiallergic agents from natural sources using mast cells activated during allergic reaction. We screened over 2000 plants for blockade of histamine release and identified two of them, S. baicalenesis and P. edulis. Bioassay-guided fractionation led to two main constituent flavonoids, baicalin from S....
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1240649
更新日期:2010-05-01 00:00:00
abstract::A crude polysaccharide fraction (DAP-1) was prepared from roots of Dipsacus asperoides by hot water extraction and EtOH precipitation, and tested for anti-complementary activity, mitogenic activity of lymphocytes, and effects on acid phosphatase and phagocytic activities of macrophages. DAP-1 showed not only anti-comp...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957720
更新日期:1997-10-01 00:00:00
abstract::The ether fraction of the defatted ethanol extract of the aerial parts of Caralluma penicillata (defl) M. E. Br. (Asclepiadaceae) yielded four new oxypregnane glycosides, penicillosides D-G. The structures of the isolated compounds were established by different spectroscopic methods. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-32078
更新日期:2002-05-01 00:00:00
abstract::The structure of albifloranine 1, a new alkaloid of ibogane type from the stem bark of Tabernaemontana albiflora (M IQ.) Pull. (Apocynaceae) has been determined. A detailed (1)H NMR study of albifloranine 1, coronaridine 2 and heyneanine 3 is presented. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-971678
更新日期:1981-01-01 00:00:00
abstract::Increased osteoclastic bone resorption plays a central role in the pathogenesis of many bone diseases. Ganoderma lucidum is known for medicinal effects such as anti-inflammatory and anti-bone resorption activities. In this study, we investigated the inhibitory effects of ganoderic acids isolated from G. lucidum on ost...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-0029-1186035
更新日期:2010-02-01 00:00:00
abstract::Four antiplatelet components were isolated from Arnebia euchroma. They inhibited the aggregation of washed rabbit platelets caused by collagen, arachidonic acid, platelet-activating factor, ADP, or thrombin. The potency of inhibiting collagen-induced platelet aggregation is in the following order: acetylshikonin (IC50...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959718
更新日期:1993-10-01 00:00:00
abstract::The structure of swertiaside, a new iridoid glucoside isolated from SWERTIA JAPONICA, was elucidated to be 7-epi-( M-hydroxybenzoyl)-loganicacid. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969779
更新日期:1984-12-01 00:00:00
abstract::Characterization of an alkali-soluble isolate from Pinus nigra Arnold (Pinaceae) seed cones by thioacidolysis revealed a significant phenylpropanoid (i.c. lignin) component which may provide the observed anti-HIV-1 activity for this substance. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957801
更新日期:1996-02-01 00:00:00
abstract::Two new sesquiterpenes, (E)-(2S,3S,6R)-atlantone-2,3-diol (1) and (E)-(2S,3S,6S)-atlantone-2,3,6-triol (2), along with two known sesquiterpenes, atlantolone (3) and (E)-α-atlantone (4), were isolated from Cedrus deodara Loud. The structures of the new compounds were elucidated on the basis of UV, IR, NMR, HR‑ESI-QTOF‑...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-0031-1280264
更新日期:2012-01-01 00:00:00
abstract::Use of herbal dietary supplements by the public is common and has been happening for centuries. In the United States, the Food and Drug Administration has a limited scope of regulation over marketed herbal dietary supplements, which may contain toxic botanical compounds that pose a public health risk. While the Food a...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/a-0605-3786
更新日期:2018-07-01 00:00:00
abstract::Baicalein, berberine, curcumin and hesperidin are the major components derived from Scutellaria baicalensis, Coptis japonica, Curcuma longa and Poncirus trifoliata, respectively. These plants have been used for the treatment of diverse chronic inflammatory diseases including respiratory disease in oriental medicine an...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-40655
更新日期:2003-06-01 00:00:00
abstract::Scientific achievements in the last two decades have revolutionized the treatment and prevention of breast cancer. This is mainly because of targeted therapies and a better understanding of the relationship between estrogen, its receptor, and breast cancer. One of these discoveries is the use of synthetic selective es...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-0028-1088304
更新日期:2008-10-01 00:00:00
abstract::The gamma-amino butyric acid (GABA) type A (GABA(A)) receptor represents a crucial target for clinical agents in the treatment of anxiety and insomnia. Using the two-microelectrode voltage clamp technique on recombinant α₁β₂γ(2S) GABA (A) receptors, effusol (1) and dehydroeffusol (2) were isolated in a bioactivity-gui...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0031-1298174
更新日期:2012-03-01 00:00:00
abstract::Chemical studies on the constituents from the dragon's blood of Dracaena cambodiana led to the discovery of three new flavonoid derivatives (1- 3) and six known compounds (4- 9). The structures of the three new compounds were elucidated by NMR and MS spectroscopic analyses. All compounds were evaluated for their growt...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-0031-1280086
更新日期:2011-12-01 00:00:00
abstract::The analysis of the volatile compounds in the essential oil of SOLIDAGO CANADENSISL. sensu lato (Compositae) GC and GC-MS demonstrated the presence of at least 36 compounds, 18 of which were identified. The Major comonenets are gamma (2)- and delta-cadinenes. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960930
更新日期:1990-04-01 00:00:00
abstract::Panaxytriol, a polyacetylenic compound, isolated from red ginseng (Panax ginseng C.A. Meyer), was studied to determine its effects on the growth and cell cycle of tumor cell lines. The compound showed both significant cytotoxicity and inhibition of DNA syntheses in various tumor cells tested. For P388D1, a mouse lymph...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-20240
更新日期:2002-02-01 00:00:00
abstract::The distribution and level of yew constituents vary with species and tissues. In this study, a rapid and valid method incorporating ultra-fast liquid chromatography (UFLC) with MS and UV detection was developed for simultaneous determination of paclitaxel and its six semisynthesis precursors in needles and hair roots ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1249959
更新日期:2010-10-01 00:00:00
abstract::The antioxidant effects of 1,5-anhydro-D-fructose (1,5-AF), a unique anhydrohexulose, were studied in 1,1-diphenyl-2-picrylhydrazyl (DPPH) solution, in human cells along with lipid peroxidation of low-density lipoprotein (LDL). We have confirmed that 1,5-AF scavenges DPPH radicals directly in solution and inhibits the...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-20050
更新日期:2002-01-01 00:00:00
abstract::The crude ethanol extract from the leaves of Dendropanax arboreus (Araliaceae) from Monteverde, Costa Rica, exhibits cytotoxic activity against Hep-G2, A-431, H-4IIE, and L-1210 tumor cell lines, but is not toxic against normal hepatocytes. The active component has been isolated by activity-directed separation and ide...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-958139
更新日期:1995-10-01 00:00:00
abstract::Five new compounds (1-5), including two limonoids, one triterpenoid, one steroid, and one sesquiterpenoid, along with nine known limonoids (6-14), were isolated from the bark of Melia azedarach. The structures of the new compounds were elucidated by 2D NMR spectroscopy and mass spectrometry. The isolated compounds as ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1328069
更新日期:2013-01-01 00:00:00
abstract::Eschsholzia californica Cham. is a traditional medicinal plant of the Indians used by the rural population of California for its analgesic and sedative properties. Our study on the aqueous extract shows that this plant reduced the behavioural parameters measured in a familiar environment test in mice (novelty preferen...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960076
更新日期:1991-06-01 00:00:00
abstract::Three new sauchinone analogues, sauchinones B-D (1-3), together with sauchinone (4), were isolated from the aerial part of Saururus chinensis. Structures of the new compounds were determined by extensive spectroscopic data as well as X-ray analysis. Compounds 3 and 4 inhibited nitric oxide production in lipopolysaccha...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0033-1351053
更新日期:2013-12-01 00:00:00
abstract::Four new phenanthroindolizidine alkaloids, tylophoridicines C-F, together with three known ones, R-(+)-deoxytylophorinidine, tylophorinine and tylophorinidine, were isolated from the roots of Tylophora atrofolliculata. The structures were determined on the basis of spectral evidence. These alkaloids exhibited cytotoxi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2004-818973
更新日期:2004-05-01 00:00:00
abstract::Medicinal herbs are increasingly used in the search for safe and efficient drug candidates for hepatitis C virus infection. In this study, we have investigated the anti-HCV effect of compounds from Mori Cortex Radicis. During a screening for extracts with anti-HCV affinity from medicinal plants (173 species), the meth...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-990249
更新日期:2007-11-01 00:00:00
abstract::In natural product research, the isolation of biomarkers or bioactive compounds from complex natural extracts represents an essential step for de novo identification and bioactivity assessment. When pure natural products have to be obtained in milligram quantities, the chromatographic steps are generally labourious an...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0035-1545912
更新日期:2015-11-01 00:00:00
abstract::The acylphloroglucinol derivative hyperforin is a major constituent of St. John's wort extracts ( Hypericum perforatum L.), which has been demonstrated to contribute to the antidepressant action of this herbal drug. In previous investigations we observed that hyperforin causes a rapid stimulation of intracellular calc...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2004-818946
更新日期:2004-04-01 00:00:00
abstract::Pancreatic cancer is one of the most aggressive human malignancies with an increasing incidence worldwide. In addition to the poor survival rates, combinations using gemcitabine as a backbone have failed to show any benefit beyond monotherapy. These facts underscore an urgent need for novel therapeutic options and mot...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1249931
更新日期:2010-08-01 00:00:00
abstract::Juniperus (Cupressaceae, Pinales) plants are widely distributed in the Qinghai-Tibet Plateau of China. The leaves and twigs of at least 8 Juniperus species (J. pingii, J. pingii var. wilsonii, J. squamata, J. recurva var. coxii, J. saltuaria, J. indica, J. tibetica and J. convallium var. microsperma) have been used as...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1194-0471
更新日期:2020-11-01 00:00:00
abstract::DNA sequence analysis of the rDNA internal transcribed spacer 1 (ITS1) and TaqMan real-time polymerase chain reaction were exploited for their applications in the differentiation of the traditional chinese medicinal plants euphorbia humifusa and e. maculata from three related adulterants e. hypericifolia, E. atoto and...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034305
更新日期:2008-02-01 00:00:00