Abstract:
:Two new sesquiterpenes, (E)-(2S,3S,6R)-atlantone-2,3-diol (1) and (E)-(2S,3S,6S)-atlantone-2,3,6-triol (2), along with two known sesquiterpenes, atlantolone (3) and (E)-α-atlantone (4), were isolated from Cedrus deodara Loud. The structures of the new compounds were elucidated on the basis of UV, IR, NMR, HR‑ESI-QTOF‑MS, and EI mass spectral studies. The n-hexane and chloroformextracts of sawdust and compounds 3 and 4 from the plant exhibited antifungal activity against Aspergillus flavus, A. niger, A. ochracoeus, A. parasiticus, and A. sydowii. A weak activity was also recorded against A. parasiticus and A. sydowii for compound 1, while Trichophyton rubrum was inhibited by compound 2 and the extracts.
journal_name
Planta Medjournal_title
Planta medicaauthors
Chaudhary A,Sood S,Kaur P,Kumar N,Thakur A,Gulati A,Singh Bdoi
10.1055/s-0031-1280264subject
Has Abstractpub_date
2012-01-01 00:00:00pages
186-8issue
2eissn
0032-0943issn
1439-0221journal_volume
78pub_type
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