Isovitexin suppresses lipopolysaccharide-mediated inducible nitric oxide synthase through inhibition of NF-kappa B in mouse macrophages.

abstract：:Plumbagin, an active principle from Plumbaginaceous plants, produced a triphasic inotropic response (first positive, second negative, and third positive phases) in guinea-pig papillary muscle. The inotropic potency of plumbagin at the first positive phase was pD2 6.40, and the methylation of 5-hydroxy group of plumbag...

journal_title：Planta medica

authors： Itoigawa M,Takeya K,Furukawa H

更新日期：1991-08-01 00:00:00

abstract：:The fruits of OSTEOPHLOEUM PLATYSPERMUM (Myristicaceae) contain sitosterol, eperu-8(20),13-dien-3alpha,15-diol, glyceryl laurodimyristate, glyceryl 1,3-lauromyristate and five neolignans: dihydroguaiaretic acid, hydroxyotobain, hydroxyoxootobain, guaiacin and otobaphenol. ...

journal_title：Planta medica

authors： Fo RB,de Carvalho MG,Gottlieb OR

更新日期：1984-02-01 00:00:00

abstract：:Four p-terphenyl derivatives named curtisians I-L (1-4) were isolated from the MeOH extract of the fruit bodies of Paxillus curtisii. Their structures were elucidated by 2D NMR, MS, IR and UV spectroscopy and chemical reaction. The absolute configurations of curtisians were determined by GC-MS on a chiral column of th...

journal_title：Planta medica

authors： Quang DN,Hashimoto T,Nukada M,Yamamoto I,Tanaka M,Asakawa Y

更新日期：2003-11-01 00:00:00

abstract：:Three new steroidal saponins were isolated from the fruits of Tribulus terrestris, and their structures were elucidated as (25R,S)-5 alpha-spirostane-12-one-3 beta-ol-3-O-beta-xylopyranosyl(1-->2)- [beta-xylopyranosyl(1-->3)]-beta-glucopyranosyl(1-->4)-[alpha-rhamno- pyranosyl(1-->2)]-beta-galactopyranoside; 26-O-beta...

journal_title：Planta medica

authors： Cai L,Wu Y,Zhang J,Pei F,Xu Y,Xie S,Xu D

更新日期：2001-03-01 00:00:00

abstract：:Five new compounds (1-5), including two limonoids, one triterpenoid, one steroid, and one sesquiterpenoid, along with nine known limonoids (6-14), were isolated from the bark of Melia azedarach. The structures of the new compounds were elucidated by 2D NMR spectroscopy and mass spectrometry. The isolated compounds as ...

journal_title：Planta medica

authors： Yuan CM,Zhang Y,Tang GH,Li Y,He HP,Li SF,Hou L,Li XY,Di YT,Li SL,Hua HM,Hao XJ

更新日期：2013-01-01 00:00:00

abstract：:Four new isoprenylated xanthones, cudraxanthones A, B and C were isolated from the N-hexane extract of the root bark of CUDRANIA TRICUSPIDATA (Carr.) Bur. (Japanese name "Hariguwa"; Moraceae), and cudraxanthone D from the benzene extract. The structures of cudraxanthones A, B, C and D were shown to be 1-4, respectivel...

journal_title：Planta medica

authors： Fujimoto T,Hano Y,Nomura T

更新日期：1984-06-01 00:00:00

abstract：:Based on the fact that Synadenium grantii is used in folk medicine for the treatment of peptic ulcers and inflammatory diseases, this work describes its chemical and pharmacological properties. Pharmacological investigation of the crude bark extract showed a high antioxidant activity over several scavenger systems, su...

journal_title：Planta medica

authors： Munhoz AC,Minozzo BR,Cruz LS,Oliveira TL,Machado WM,Pereira AV,Fernandes D,Manente FA,Vellosa JC,Nepel A,Barison A,Beltrame FL

更新日期：2014-04-01 00:00:00

abstract：:Aloe barbadensis polysaccharide was partially digested with cellulase and further purified by dialysis, stepwise ethanol precipitation, and size exclusion chromatography. Crude modified Aloe polysaccharide (MAP) activated macrophage cells and stimulated fibroblast growth. Under the same conditions, native Aloe barbade...

journal_title：Planta medica

authors： Qiu Z,Jones K,Wylie M,Jia Q,Orndorff S

更新日期：2000-03-01 00:00:00

abstract：:The flowers of ARNICA MOLLIS afforded, in addition to baileyin ( 1A), baileyin acetate ( 1B), xanthalongin ( 3), and 2-deacetoxy-11alpha,13-dihydroxanthuminol ( 6), the new 1,5- CIS-guaianolides arnimollin acetate ( 2A) and arnimollin tiglinate ( 2A) and the new xanthanolides 11beta3,13-dihydroxanthalongin ( 4) and 11...

journal_title：Planta medica

authors： Marcinek-Hüpen-Bestendonk C,Willuhn G,Steigel A,Wendisch D,Middelhauve B,Wiebcke M,Mootz D

更新日期：1990-02-01 00:00:00

abstract：:Recently, we showed that intravenous (i.v.) treatment with the essential oil of Mentha x villosa (EOMV) in pentobarbitone-anaesthetised rats decreased blood pressure; the effect occurred independently of the presence of an operational central autonomic drive to the cardiovascular system. This finding suggested that th...

journal_title：Planta medica

authors： Lahlou S,Magalhães PJ,Carneiro-Leão RF,Leal-Cardoso JH

更新日期：2002-08-01 00:00:00

abstract：:Four new neolignan glucosides, longiflorosides A, B, C and D, in addition to one known neolignan glucoside, dehydro-diconiferyl alcohol-4-O-beta-D-glucopyranoside were obtained from whole plants of Pedicularis longiflora. The structures of these compounds were determined mainly on spectral evidence. ...

journal_title：Planta medica

authors： Wang CZ,Jia ZJ

更新日期：1997-06-01 00:00:00

abstract：:Bioassay-guided isolation of two new compounds, 3,4-methylenedioxy-3'-O-methyl-4'-O-glucoside ellagic acid (1) and the pteleoellagic acid derivative (2), from the stem bark of Pteleopsis hylodendron is reported along with 3,4-methylenedioxy-3'-O-methyl ellagic acid (3), 3,3'-di-O-methyl ellagic acid (4) and 3,3',4'-tr...

journal_title：Planta medica

authors： Atta-Ur-Rahman,Ngounou FN,Choudhary MI,Malik S,Makhmoor T,Nur-E-Alam M,Zareen S,Lontsi D,Ayafor JF,Sondengam BL

更新日期：2001-06-01 00:00:00

abstract：:Bioactivity-directed separation led to the identification of four compounds, viz. denbinobin (1), 3,7-dihydroxy-2,4-dimethoxyphenanthrene (2), 3-methylgigantol (3), and erianthridin (4) from the ethanolic extract of Ephemerantha lonchophylla. Antiplatelet tests were carried out using 4 different aggregation inducers, ...

journal_title：Planta medica

authors： Chen CC,Huang YL,Teng CM

更新日期：2000-05-01 00:00:00

abstract：:Propolis is a cereus resin with a complex chemical composition that possesses a wide range of biological activities. The aim of this study was to evaluate the in vitro anti-Giardia lamblia activity of Sonoran propolis collected from three different areas of Sonoran Desert in northwestern Mexico (Caborca, Pueblo de Ala...

journal_title：Planta medica

authors： Alday-Provencio S,Diaz G,Rascon L,Quintero J,Alday E,Robles-Zepeda R,Garibay-Escobar A,Astiazaran H,Hernandez J,Velazquez C

更新日期：2015-06-01 00:00:00

abstract：:The hypoglycemic activity of olive leaf was studied. Maximum hypoglycemic activity was obtained from samples collected in the winter months, especially in February. One of the compounds responsible for this activity was oleuropeoside, which showed activity at a dose of 16 mg/kg. This compound also demonstrated antidia...

journal_title：Planta medica

authors： Gonzalez M,Zarzuelo A,Gamez MJ,Utrilla MP,Jimenez J,Osuna I

更新日期：1992-12-01 00:00:00

abstract：:Herpes simplex virus infections persist throughout the lifetime of the host and affect more than 80 % of the humans worldwide. The intensive use of available therapeutic drugs has led to undesirable effects, such as drug-resistant strains, prompting the search for new antiherpetic agents. Although diverse bioactivitie...

journal_title：Planta medica

authors： Nocchi SR,Companhoni MV,de Mello JC,Dias Filho BP,Nakamura CV,Carollo CA,Silva DB,Ueda-Nakamura T

更新日期：2017-04-01 00:00:00

abstract：:In natural product chemistry, it is often crucial to determine sugar composition as well as the absolute configuration of each monosaccharide in glycosides. An ultra-performance liquid chromatography method using both photodiode array (PDA) and mass spectrometry detectors (UPLC-UV/MS) was developed for qualitative ana...

journal_title：Planta medica

authors： Wang YH,Avula B,Fu X,Wang M,Khan IA

更新日期：2012-05-01 00:00:00

abstract：:Based on rDNA ITS sequences of D. officinale and the other 37 species of Dendrobium, a pair of allele-specific diagnostic primers, TP-JB01S and TP-JB01X, were designed to authenticate D. officinale from the other species. Before the diagnostic PCR, the primer pair, P1 and P2, for amplifying the whole ITS region was us...

journal_title：Planta medica

authors： Ding X,Wang Z,Zhou K,Xu L,Xu H,Wang Y

更新日期：2003-06-01 00:00:00

abstract：:EGFR, as a critical signaling pathway in many human tumors, has become an important target of cancer drug design. Taspine has shown meaningful angiogenesis activity in previous studies. This paper is to investigate the antitumor action of taspine by modulating the EGFR signaling pathway. The study determined the expre...

journal_title：Planta medica

authors： Zhang Y,Zheng L,Zhang J,Dai B,Wang N,Chen Y,He L

更新日期：2011-11-01 00:00:00

abstract：:Thirty-five flavonoids of seven different types, namely isoflavonoids, chalcones, dihydroflavonols, flavanols, flavanones, flavones, and flavonols were investigated for their ability to inhibit ascorbate-induced microsomal lipid peroxidation and their cytotoxicity. For each activity a structure-activity relationship w...

journal_title：Planta medica

authors： Cos P,Calomme M,Sindambiwe JB,De Bruyne T,Cimanga K,Pieters L,Vlietinck AJ,Vanden Berghe D

更新日期：2001-08-01 00:00:00

abstract：:The present study aimed to investigate standardized ethanol extracts of fruit and leaves of Piper sarmentosum for their in vivo antioxidant activity in rats using a CCl (4)-induced oxidative stress model. The standardization was based on the quantification of the markers pellitorine, sarmentine and sarmentosine by hig...

journal_title：Planta medica

authors： Hussain K,Ismail Z,Sadikun A,Ibrahim P

更新日期：2010-03-01 00:00:00

abstract：:Quality control of drugs consists of identifying the raw material to avoid unwanted admixtures or exchange of material as well as looking for abiotic and biotic contaminations. So far, identity and microbial contamination are analyzed by separate processes and separate methods. Species identification by their DNA ("DN...

journal_title：Planta medica

authors： Schmiderer C,Lukas B,Ruzicka J,Novak J

更新日期：2018-04-01 00:00:00

abstract：:In this study the first supercritical fluid based protocol for the extraction, analysis, and isolation of six polar compounds, i.e., o-vanillin (1), styracin (2), vanillin (3), trans-cinnamic acid (4), vanillic acid (5), and shikimic acid (6), was developed. First, eight styrax resin products (R1-R8) obtained from var...

journal_title：Planta medica

authors： Scheuba J,Wronski VK,Rollinger JM,Grienke U

更新日期：2017-08-01 00:00:00

abstract：:Metabolic fingerprinting techniques have received a lot of attention in recent years and the annual amount of publications in this field has increased significantly over the past decade. This increase in publications is due to improvements in the analytical performance, most notably in the field of NMR and MS analysis...

journal_title：Planta medica

authors： van der Kooy F,Maltese F,Choi YH,Kim HK,Verpoorte R

更新日期：2009-06-01 00:00:00

abstract：:Aerial parts of Pterocaulon polystachyum from Chaco province, Argentina, afforded the known coumarins ayapin, isoscopoletin, prenyletin, prenyletin methyl ether, virgatenol, obtusinin, 5-methoxy-6,7-methylenedioxycoumarin, 5-(3,3-dimethylallyloxy)-6,7-methylenedioxycoumarin, 5-(2',3'-dihydroxy-3-methylbutanoxy)-6,7-me...

journal_title：Planta medica

authors： Vera N,Bardón A,Catalán CA,Gedris TE,Herz W

更新日期：2001-10-01 00:00:00

abstract：:In this study, the significant hepatoprotective effect of dioscin against CCl₄-induced acute liver damage in mice was first discovered, and the effect produced by dioscin at the dose of 100 mg/kg was equal to the action produced by silymarin at the dose of 200 mg/kg. Then, 1-dimension gel electrophoresis was used to s...

journal_title：Planta medica

authors： Lu B,Yin L,Xu L,Peng J

更新日期：2011-03-01 00:00:00

abstract：:The specific physiological responses induced by inhaling R-(-)- as well as S-(+)-linalool in 24 human subjects undergoing experimental stress were investigated in this study. Various physiological parameters of the autonomous nervous system (heart rate, blood pressure, electrodermal activity) as well as the endocrine ...

journal_title：Planta medica

authors： Höferl M,Krist S,Buchbauer G

更新日期：2006-10-01 00:00:00

abstract：:Leaves of Ligustrum vulgare (common privet) have been used for treatment of oropharyngeal inflammations or as antirheumatic, diuretic, and hypotensive agents in folk medicine in southern Europe. Taking into account that neutrophils are involved in the inflammation, the aim of the study was to determine the effect of a...

journal_title：Planta medica

authors： Czerwińska ME,Granica S,Kiss AK

更新日期：2013-07-01 00:00:00

abstract：:Dioscoretine isolated from the aqueous fraction of the methanol extract of Dioscorea dumetorum tubers when administered intra-peritoneally to normal and alloxan diabetic rabbits produces significant hypoglycaemic effects at a dose of 20 mg/kg. The fasting blood sugar in normoglycaemic rabbits was reduced from 112 mg/1...

journal_title：Planta medica

authors： Iwu MM,Okunji CO,Ohiaeri GO,Akah P,Corley D,Tempesta MS

更新日期：1990-06-01 00:00:00

abstract：:Protopanaxatriol and protopanaxadiol exhibit limited oral bioavailability due to the poor solubility and intestinal cytochromes P450-mediated metabolism. This study set out to develop a novel cytochromes P450 inhibitory excipient(s)-based self-microemulsion to encapsulate protopanaxatriol and protopanaxadiol so as to ...

journal_title：Planta medica

authors： Yang F,Zhou J,Liu C,Hu X,Pan R,Chang Q,Liu X,Liao Y

更新日期：2017-03-01 00:00:00