Abstract:
:The specific physiological responses induced by inhaling R-(-)- as well as S-(+)-linalool in 24 human subjects undergoing experimental stress were investigated in this study. Various physiological parameters of the autonomous nervous system (heart rate, blood pressure, electrodermal activity) as well as the endocrine system (salivary cortisol) were monitored. The study clearly indicated that odorants can modulate salivary cortisol levels, with both linalool enantiomers exerting relaxing effects. Concerning blood pressure and heart rate, S-(+)-linalool acted as an activating agent in contrast to electrodermal activity. R-(-)-linalool proved to be stress-relieving as determined by heart rate. In conclusion, the results revealed that (1) chirality crucially influences the physiological effects of odorants and that (2) odorants may act differently on certain physiological parameters.
journal_name
Planta Medjournal_title
Planta medicaauthors
Höferl M,Krist S,Buchbauer Gdoi
10.1055/s-2006-947202subject
Has Abstractpub_date
2006-10-01 00:00:00pages
1188-92issue
13eissn
0032-0943issn
1439-0221journal_volume
72pub_type
杂志文章,随机对照试验相关文献
PLANTA MEDICA文献大全abstract::Seven new clerodane diterpenoids, dysoxydensins A-G (1-7), together with six known clerodanes, were isolated from Dysoxylum densiflorum. The structures of all the compounds were elucidated by extensive spectroscopic analysis. These compounds were evaluated for their cytotoxic activities against five human cancer cell ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0034-1382903
更新日期:2014-08-01 00:00:00
abstract::Bioassay-guided isolation of two new compounds, 3,4-methylenedioxy-3'-O-methyl-4'-O-glucoside ellagic acid (1) and the pteleoellagic acid derivative (2), from the stem bark of Pteleopsis hylodendron is reported along with 3,4-methylenedioxy-3'-O-methyl ellagic acid (3), 3,3'-di-O-methyl ellagic acid (4) and 3,3',4'-tr...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-14306
更新日期:2001-06-01 00:00:00
abstract::Four new isoprenylated xanthones, cudraxanthones A, B and C were isolated from the N-hexane extract of the root bark of CUDRANIA TRICUSPIDATA (Carr.) Bur. (Japanese name "Hariguwa"; Moraceae), and cudraxanthone D from the benzene extract. The structures of cudraxanthones A, B, C and D were shown to be 1-4, respectivel...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969682
更新日期:1984-06-01 00:00:00
abstract::One new diterpene, 2 alpha-hydroxy-12beta-hydroxy-isopimara-8(14), 15-diene, and six known compounds as triterpenes, sterols and fatty acid, were isolated from the stem bark of Tanaecium jaroba (Bignoniaceae), a Bolivian plant used in traditional medicine. Their structures were established mainly by 1D and 2D NMR (COS...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-32553
更新日期:2002-06-01 00:00:00
abstract::During activity-guided fractionations to screen for antineoplastic agents, further studies by means of preparative HPLC led to the isolation of four known furostanol saponins: protoneodioscin, protodioscin, protoneogracillin, protogracillin, along with their corresponding artifacts: methyl protoneodioscin, methyl prot...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957636
更新日期:1997-04-01 00:00:00
abstract::Scutellariae Radix (SR), the root of Scutellaria baicalensis (Labiatae), is widely used in clinical Chinese medicine. In order to investigate the effect of SR on the absorption and disposition of cyclosporine, rats were administered with cyclosporine orally (in the form of the microemulsion Neoral and intravenously wi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2004-815489
更新日期:2004-02-01 00:00:00
abstract::Scientific achievements in the last two decades have revolutionized the treatment and prevention of breast cancer. This is mainly because of targeted therapies and a better understanding of the relationship between estrogen, its receptor, and breast cancer. One of these discoveries is the use of synthetic selective es...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-0028-1088304
更新日期:2008-10-01 00:00:00
abstract::The dried rhizome of Panax notoginseng is a traditional Chinese herb extensively used for treatment of cardiovascular diseases and other ailments. Panax notoginseng saponins (PNS) are known as the major pharmacologically active constituents. The purpose of this study was to investigate the cardioprotective effects of ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034303
更新日期:2008-02-01 00:00:00
abstract::Aerial parts of Pterocaulon polystachyum from Chaco province, Argentina, afforded the known coumarins ayapin, isoscopoletin, prenyletin, prenyletin methyl ether, virgatenol, obtusinin, 5-methoxy-6,7-methylenedioxycoumarin, 5-(3,3-dimethylallyloxy)-6,7-methylenedioxycoumarin, 5-(2',3'-dihydroxy-3-methylbutanoxy)-6,7-me...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-17365
更新日期:2001-10-01 00:00:00
abstract::Products derived from Noni fruit (Morinda citrifolia) have been commercialised in the USA since the 1990s and are increasingly distributed all over the world. A large number of beneficial effects have been claimed for Noni. Fruit juice of Noni has been approved as a Novel Food by the European Commission in 2003. This ...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-2007-967115
更新日期:2007-03-01 00:00:00
abstract::Barbaloin levels in the exudates from the leaves of 68 species of ALOE in the Kew collection have been determined by light absorption at 375 nm following separation by HPLC. The exudates from most species contained between 10-20% although a few concentrations of around 30% were found. The level in the leaf was usually...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-962735
更新日期:1987-08-01 00:00:00
abstract::Antioxidants such as vitamin E may act differently on skin cells depending on the age of the skin and the level of oxidative damage induced. The effects of alpha-tocopherol (ATF) on H(2)O(2)-induced DNA damage and telomere shortening of normal human skin fibroblast cells derived from young and old individual donors we...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1240812
更新日期:2010-06-01 00:00:00
abstract::Lime flowers, traditionally used for medical purposes for the treatment of symptoms of the common cold and mental stress, consist of the dried inflorescences including the floral bracts of Tilia cordata, Tilia platyphyllos, Tilia × vulgaris, or mixtures thereof. During phytochemical investigations, 6 different alkaloi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1340-0099
更新日期:2021-01-12 00:00:00
abstract::The effects of the essential oil of Mentha pulegium L. (EOMP), a plant commonly known as "pennyroyal" or "poejo" that is used in folk medicine as an abortifaceant, were assessed on the isolated rat myometrium. Myometrial strips were stimulated with 10 nM oxytocin or 10 microM PGF (2alpha). EOMP (10 - 300 microg/mL) co...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-837819
更新日期:2005-03-01 00:00:00
abstract::Two triterpenoidal saponins having phytolaccagenin as the aglycone were isolated from the roots of Phytolacca esculenta (Phytolaccaceae). The structures of two new saponins, esculentoside I and esculentoside N, were established to be 3-O-[beta-D-glucopyranosyl-(1----4)-beta-D- glucopyranosyl]-28-O-beta-D-glucopyranosy...
journal_title:Planta medica
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract::Shoot primordia, which were able to propagate vegetatively with a very high rate and to redifferentiate easily to new plants, were induced from shoot tips of Stevia rebaudiana Bertoni on Gamborg B5 medium containing 6-benzylaminopurine (BAP) and alpha-naphthaleneacetic acid (NAA) under light. The propagation of the sh...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969165
更新日期:1986-08-01 00:00:00
abstract::Five new compounds (1-5), including two limonoids, one triterpenoid, one steroid, and one sesquiterpenoid, along with nine known limonoids (6-14), were isolated from the bark of Melia azedarach. The structures of the new compounds were elucidated by 2D NMR spectroscopy and mass spectrometry. The isolated compounds as ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1328069
更新日期:2013-01-01 00:00:00
abstract::Two new C(18) dibenzocyclooctadiene lignans named heteroclitalignans A and B (1 and 3), one new C(19) homolignan named heteroclitalignan C(4) and one new natural product named heteroclitalignan D(2), together with the four known lignans kadsurarin (5), kadsulignan E (6), d-epigalbacin, and meso-dihydroguaiaretic acid ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-916213
更新日期:2006-02-01 00:00:00
abstract::Both borneol and menthol are bioactive substances derived from Chinese herbal medicines. In order to understand the pharmacokinetics of borneol and menthol in Qingyan drop pills, a rapid, sensitive, and simple gas chromatographic (GC) method with flame ionization detection (FID) was developed for the simultaneous dete...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1270998
更新日期:2011-09-01 00:00:00
abstract::The effect of extracts of MOMORDICA CHARANTIA L. fruits on glucose metabolism and glucose uptake was investigated. The fruit of momordica, at all ripening stages, was found to contain two inhibitory compounds: one against hexokinase activity and the other against glucose uptake by rat intestinal fragments. Both inhibi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969380
更新日期:1985-02-01 00:00:00
abstract::This Paper describes an improved HPLC method for the determination of pentacyclic oxindole alkaloids in Uncaria tomentosa (Cat's Claw). Six of the isomeric compounds could be baseline separated at room temperature within less than 30 min by using 3 microm C-18 column material and a mobile phase consisting of 10 mM pho...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-15824
更新日期:2001-07-01 00:00:00
abstract::Malaria treatment and control have become increasingly difficult because of the spread of drug-resistant strains of Plasmodium falciparum and Plasmodium vivax. Thus, there is a continuous need to develop new combination therapies such as artemisinin-based combination therapies (ACTs) to contrast the emergence of resis...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0952-3677
更新日期:2019-08-01 00:00:00
abstract::Synthetic butylidenephthalide (Bdph), 60 mg/kg per os (p.o.) given 3 h prior to injection of pituitrin (4 U/kg, i.v.), significantly prevented T-wave lowering on lead II electrocardiograph in unanesthetized rats. The effective dose, 60 mg/kg, was about 1/56th of the median lethal dose (LD50, p.o.) in rats. However, Bd...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957415
更新日期:1998-04-01 00:00:00
abstract::Raspberry ketone (RK) is a natural phenolic compound of the red raspberry. The dietary administration of RK to male mice has been reported to prevent high-fat diet-induced elevation in body weight and to increase lipolysis in white adipocytes. To elucidate a possible mechanism for the antiobesity action of RK, its eff...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1249860
更新日期:2010-10-01 00:00:00
abstract::The special extract of Cimicifuga racemosa (CR) BNO 1055 was shown to have bone protective effects without exerting estrogenic effects in the uterus or mammary gland. Whether the effects of CR BNO 1055 would be exerted in other organs that also express estrogen receptors (ERs) but in which the effects of estrogens and...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185561
更新日期:2009-10-01 00:00:00
abstract::Cannabis (Cannabis sativa L.) is an annual herbaceous plant that belongs to the family Cannabaceae. Trans-Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) are the two major phytocannabinoids accounting for over 40% of the cannabis plant extracts, depending on the variety. At the University of Mississippi, differ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-124088
更新日期:2018-03-01 00:00:00
abstract::A cell-based method for screening drug candidates from herbal extracts that have possible anti-type II diabetic effects was established. The differentiation of preadipocytes into adipocytes was used as a sensitive primary indicator of a drug's potential effect on type II diabetes. We established a quantitative method ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-916215
更新日期:2006-01-01 00:00:00
abstract::The distribution and level of yew constituents vary with species and tissues. In this study, a rapid and valid method incorporating ultra-fast liquid chromatography (UFLC) with MS and UV detection was developed for simultaneous determination of paclitaxel and its six semisynthesis precursors in needles and hair roots ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1249959
更新日期:2010-10-01 00:00:00
abstract::Activator protein 1 (AP-1) is a transcription factor which plays a critical role in inflammation and carcinogenesis. The present study was conducted to investigate the effect of berberine, an isoquinoline alkaloid present in plants of the genera Berberis and Coptis, on the activity of AP-1 using a reporter gene assay ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-960795
更新日期:1999-05-01 00:00:00
abstract::From the roots of Aconitum crassicaule, two new diterpenoid alkaloids, crassicaulisine and crassicaulidine, were isolated. The structure of crassicaulisine, C (24)H (39)O (7)N, has been elucidated as 3 on the basis of chemical and spectral data, while the structure of crassicaulidine, C (24)H (39)O (8)N, has been show...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969945
更新日期:1983-01-01 00:00:00