A preadipocyte differentiation assay as a method for screening potential anti-type II diabetes drugs from herbal extracts.

abstract：:A new eudesmanolide sesquiterpene, sivasinolide 6-O-angelate (1), was isolated from the aerial parts of Anthemis ruthenica together with the known compounds chrysanin (2), tanacin (3), 3 beta-hydroxycostunolide (4), centauridin (5), and centaureidin (6). The compounds were obtained by means of bioactivity-guided fract...

journal_title：Planta medica

authors： Hajdú Z,Zupkó I,Réthy B,Forgo P,Hohmann J

更新日期：2010-01-01 00:00:00

abstract：:Ginsenosides are the major principles of Panax ginseng C. A. Meyer (Araliaceae) used as a mild oriental folk medicine. In this report, we have examined the inhibitory potency of protopanaxadiol ginsenosides (PPDGs) such as Rb1, Rb2 and Rc, and their co-treatment effect with known tumor necrosis factor (TNF)-alpha anta...

journal_title：Planta medica

authors： Cho JY,Yoo ES,Baik KU,Park MH,Han BH

更新日期：2001-04-01 00:00:00

abstract：:In this study we investigated the effects of concomitant food intake on the bioavailability of distinct boswellic acids (BAs) from the test preparation BSE-018, a dry extract from Boswellia serrata gum resin. In a randomised, open, single-dose, two-way crossover study, healthy male subjects received three capsules of ...

journal_title：Planta medica

authors： Sterk V,Büchele B,Simmet T

更新日期：2004-12-01 00:00:00

abstract：:Ocimum basilicum L. is an aromatic herb used in Brazil to treat illnesses such as respiratory and rheumatic problems, vomiting, and pain. In the present study, the chemical composition, acute toxicity, and antinociceptive effects of the essential oil (EO) of the cultivar "Maria Bonita" obtained from O. basilicum L. PI...

journal_title：Planta medica

authors： Venâncio AM,Onofre AS,Lira AF,Alves PB,Blank AF,Antoniolli AR,Marchioro M,Estevam Cdos S,de Araujo BS

更新日期：2011-05-01 00:00:00

abstract：:Ligusticum canbyi (J.M. Coult & Rose) is a medicinal understory forest species used in traditional rituals and ceremonies for spiritual enlightenment and improved mental health. Very little is known about the phytochemical complexity or diversity of L. canbyi tissues or extracts. The current study was undertaken to de...

journal_title：Planta medica

authors： Turi CE,Murch SJ

更新日期：2013-09-01 00:00:00

abstract：:Shoot-tips from several genotypes of the cardenolide-producing perennial shrub Digitalis obscura L. were successfully cryopreserved using the encapsulation-dehydration technique. Precultivation on MS medium containing 0.5 M sucrose, followed by 2.5 h dehydration (final weight 30 %) induced shoot regrowth in 42 % of cr...

journal_title：Planta medica

authors： Sales E,Nebauer SG,Arrillaga I,Segura J

更新日期：2001-12-01 00:00:00

abstract：:Cordatolide A and B were re-isolated from Calophyllum cordato-oblongum, an endemic species of Sri Lanka, and found to inhibit HIV-1 reverse transcriptase with IC50 values of 12.3 and 19.0 microM, respectively. ...

journal_title：Planta medica

authors： Dharmaratne HR,Wanigasekera WM,Mata-Greenwood E,Pezzuto JM

更新日期：1998-06-01 00:00:00

abstract：:Capsaicin and 6-gingerol, pungent components of chilli pepper and ginger, are known as dietary agonists of transient receptor potential vanilloid-1. Transient receptor potential vanilloid-1 nerve fibers are recognized to play a role in gastric mucosal integrity in rats. In the present studies, we examined the acute ef...

journal_title：Planta medica

authors： Okumi H,Tashima K,Matsumoto K,Namiki T,Terasawa K,Horie S

更新日期：2012-11-01 00:00:00

abstract：:A new tetrahydrofuran lignan, named henricine ( 1), was isolated from the stems of SCHISANDRA HENRYI. High resolution COSY spectrum was used in the structural elucidation. ...

journal_title：Planta medica

authors： Lian-Niang L,Hong X

更新日期：1986-12-01 00:00:00

abstract：:The nor-kaurane diterpene Atractyliretin was obtained by acid hydrolysis of Atractyloside, a toxic substance isolated from ATRACTYLIS GUMMIFERA L (Compositae). On the basis of spectral (IR, (1)H-NMR, (13)C-NMR and MS) analysis and chemical degradation its structure and stereochemistry was identified as 4. ...

journal_title：Planta medica

authors： Camarda L,Ceraulo L,Ferrugia M,Pascual C,Sprio V

更新日期：1986-10-01 00:00:00

abstract：:The aim of the present study was to investigate the antistress potential of LABISIA PUMILA aqueous extract (LPPM/A003) using a battery of tests widely employed in different stressful situations. Pretreatment of experimental animals with LPPM/A003 caused an increase in the swimming endurance and hypoxia time and also s...

journal_title：Planta medica

authors： Kour K,Sharma N,Chandan BK,Koul S,Sangwan PL,Bani S

更新日期：2010-10-01 00:00:00

abstract：:The roots of Cryptolepis sanguinolenta have been investigated for their chemical composition since 1931 but so far no studies on the leaves have been reported although they are used in traditional medicine in Guinea-Bissau. Two new alkaloids identified as cryptolepinoic acid (1) and methyl cryptolepinoate (2) and the ...

journal_title：Planta medica

authors： Paulo A,Gomes ET,Steele J,Warhurst DC,Houghton PJ

更新日期：2000-02-01 00:00:00

abstract：:The new diterpenoids, candesalvoquinone, 12- O-methylcandesalvone B, candesalvone B methyl ester with the 3,4-secoabietane skeleton, and candelabroquinone with the abietane skeleton were isolated from the aerial parts of Salvia candelabrum, together with the known compound candelabrone. The structures were established...

journal_title：Planta medica

authors： Hohmann J,Janicsák G,Forgo P,Rédei D,Máthé I,Bartók T

更新日期：2003-03-01 00:00:00

abstract：:A method was developed to distinguish Vaccinium species based on leaf extracts using nuclear magnetic resonance spectroscopy. Reference spectra were measured on leaf extracts from several species, including lowbush blueberry (Vaccinium angustifolium), oval leaf huckleberry (Vaccinium ovalifolium), and cranberry (Vacci...

journal_title：Planta medica

authors： Markus MA,Ferrier J,Luchsinger SM,Yuk J,Cuerrier A,Balick MJ,Hicks JM,Killday KB,Kirby CW,Berrue F,Kerr RG,Knagge K,Gödecke T,Ramirez BE,Lankin DC,Pauli GF,Burton I,Karakach TK,Arnason JT,Colson KL

更新日期：2014-06-01 00:00:00

abstract：:In this study we investigate the active constituents of the rhizome of Zingiber officinale, Roscoe (ginger) and determine their activity on glucose uptake in cultured L6 myotubes and the molecular mechanism underlying this action. Freeze-dried ginger powder was extracted with ethyl acetate (1 kg/3 L) to give the total...

journal_title：Planta medica

authors： Li Y,Tran VH,Duke CC,Roufogalis BD

更新日期：2012-09-01 00:00:00

abstract：:The crude extract (IPA) of the plant Ipomoea pes-caprae (L.) R. Br. showed an inhibitory effect on prostaglandin synthesis in vitro. Bioassay-guided separation of the extract led to the isolation of four active compounds: 2-hydroxy-4,4,7-trimethyl-1(4H)-naphthalenone (1), (-)-mellein (2), eugenol (3), and 4-vinyl-guai...

journal_title：Planta medica

authors： Pongprayoon U,Baeckström P,Jacobsson U,Lindström M,Bohlin L

更新日期：1991-12-01 00:00:00

abstract：:A MeOH extract prepared from culture of an actinomycete Streptomyces sp. HZP-2216E isolated from marine green algae Ulva pertusa was found to significantly inhibit proliferation of human glioma cells. Two different media were applied to culture this marine actinomycete, which produced two new compounds of 23-O-butyryl...

journal_title：Planta medica

authors： Zhang Z,Chen L,Zhang X,Liang Y,Anjum K,Chen L,Lian XY

更新日期：2017-12-01 00:00:00

abstract：:Six dietary isothiocyanates, allyl-isothiocyanate, benzyl-isothiocyanate, phenylethyl-isothiocyanate, sulforaphane, erucin, and iberin, were tested for their trypanocidal activities in vitro using culture-adapted bloodstream forms of Trypanosoma brucei. All isothiocyanates showed a dose-dependent effect on the growth ...

journal_title：Planta medica

authors： Steverding D,Michaels S,Read KD

更新日期：2014-02-01 00:00:00

abstract：:Extraction of PIPER RIBESOIDES Wall, furnished the new linalool derivative (+)-3,7-dimethyl-3-hydroxy-4-( P-coumaryloxy)-1,6-octadiene, the lignans (-)-hinokinin and (-)-cubebin, N-isobutyl-2 E,4 E-deca-2,4-dienamide, methyl piperate, methyl 2 E,4 E,6 E-7-phenyl-2,4,6-heptatrienoate, palmitic acid, stearic acid, and b...

journal_title：Planta medica

authors： Kijjoa A,Pinto MM,Tantisewie B,Herz W

更新日期：1989-04-01 00:00:00

abstract：:A study of secondary metabolites from the bark of Alnus glutinosa led to the isolation of fourteen diarylheptanoids: oregonin (1), platyphylloside (2), rubranoside A (3), rubranoside B (4), hirsutanonol (5), hirsutenone (6), hirsutanonol-5-O-β-D-glucopyranoside (7), platyphyllonol-5-O-β-D-xylopyranoside (8), aceroside...

journal_title：Planta medica

authors： Novaković M,Stanković M,Vučković I,Todorović N,Trifunović S,Tešević V,Vajs V,Milosavljević S

更新日期：2013-04-01 00:00:00

abstract：:A beta-hydroxychalcone 1, so far not reported as a natural compound, was separated from the diethyl ether extract of LEPTOSPERMUM SCOPARIUM (Myrtaceae). Furthermore, three known flavonoids 2-4 were isolated. The (13)C-NMR spectra of 2-4 are reported, since they have as yet not been reported in the literature. ...

journal_title：Planta medica

authors： Mayer R

更新日期：1993-06-01 00:00:00

abstract：:Callus induction starting from the rhizome tissue of plants of three CURCUMA species: CURCUMA ZEDOARIA Roscoe, C. DOMESTICA Valeton, and C. AROMATICA Salisbury (Zingiberaceae) was performed. Successful callus formation was obtained in all three species using Murashige-Skoog's (MS) medium supplemented with 1-naphthalen...

journal_title：Planta medica

authors： Yasuda K,Tsuda T,Shimizu H,Sugaya A

更新日期：1988-02-01 00:00:00

abstract：:Volatile constituents of the essential oils from leaves and inflorescences of Solidago chilensis Meyen were analyzed by GC-FID, GC-MS and 13C-NMR and thirty-six different compounds were identified. Pumiloxide, an unusual labdane diterpene, was found to be one of the major components in both oils (15.3 % and 12.3 %, re...

journal_title：Planta medica

authors： Vila R,Mundina M,Tomi F,Furlán R,Zacchino S,Casanova J,Cañigueral S

更新日期：2002-02-01 00:00:00

abstract：:Guinea pigs were sensitized with trinitrophenylated liver macromolecular protein fraction (TNP-LP1) prepared by using sodium trinitrobenzenesulfonate of strong immunogenicity as the hapten and LP1 as the carrier protein. The administration of trinitrophenylated hepatocytes and lipopolysaccharide to these TNP-LP1-sensi...

journal_title：Planta medica

authors： Mizoguchi Y,Shin T,Kobayashi K,Morisawa S

更新日期：1991-02-01 00:00:00

abstract：:The inhibitory effects of selected phenolic lichen substances were tested against a panel of methicillin- and multidrug-resistant Staphylococcus aureus. Depsidones with long alkyl chains on both of the aromatic rings were consistently active against the strains tested, comparable to or better than the level of clinica...

journal_title：Planta medica

authors： Kokubun T,Shiu WK,Gibbons S

更新日期：2007-02-01 00:00:00

abstract：:The studies were carried out to evaluate the constituents in the aerial part of Aconitum chiisanense (Ranunculaceae). From the butanol fraction of the methanol extract, kaempferol 3- O-beta-glucopyranoside-7- O-(6-trans-caffeoyl)-beta-glucopyranosyl-(1-->2)-alpha-rhamnopyranoside (I), quercetin 3- O-beta-glucopyranosi...

journal_title：Planta medica

authors： Jeong HJ,Whang WK,Kim IH

更新日期：1997-08-01 00:00:00

abstract：:DNA sequence analysis of the rDNA internal transcribed spacer 1 (ITS1) and TaqMan real-time polymerase chain reaction were exploited for their applications in the differentiation of the traditional chinese medicinal plants euphorbia humifusa and e. maculata from three related adulterants e. hypericifolia, E. atoto and...

journal_title：Planta medica

authors： Xue HG,Wang H,Li DZ,Xue CY,Wang QZ

更新日期：2008-02-01 00:00:00

abstract：:Two new compounds, methyl 3-chloro-6-hydroxy-2-(4-hydroxy-2-methoxy-6-methylphenoxy)-4-methoxybenzoate (1) and (2 S,5' R,E)-7-hydroxy-4,6-dimethoxy-2-(1-methoxy-3-oxo-5-methylhex-1-enyl)-benzofuran-3(2H)-one (2), together with four known compounds, griseofulvin (3), dechlorogriseofulvin (4), bostrycin (5), and deoxybo...

journal_title：Planta medica

authors： Xia X,Li Q,Li J,Shao C,Zhang J,Zhang Y,Liu X,Lin Y,Liu C,She Z

更新日期：2011-10-01 00:00:00

abstract：:The immunomodulatory activity of HN-02, an extract containing a mixture of andrographolides (i.e., andrographolide [88 +/- 5 %] plus 14-deoxyandrographolide and 14-deoxy-11,12-didehydroandrographolide together [12 +/- 3 %]) in a pure powder form was evaluated at 1.0, 1.5, and 2.5 mg/kg on different in vivo and in vitr...

journal_title：Planta medica

authors： Naik SR,Hule A

更新日期：2009-06-01 00:00:00

abstract：:A total of 18 purified lignans was evaluated for antiviral activity against murine cytomegalovirus (CMV) and Sindbis virus, by means of different treatment regimens. Podophyllotoxin and alpha-peltatin were the most potent compounds, and they apparently inhibited murine CMV at an essential early step in the replication...

journal_title：Planta medica

authors： MacRae WD,Hudson JB,Towers GH

更新日期：1989-12-01 00:00:00