Bioactivity-guided isolation of cytotoxic sesquiterpenes and flavonoids from Anthemis ruthenica.

abstract：:The investigation of the aerial parts of two collections of AMBROSIA MARITIMA afforded in addition to known pseudoguaianolides nine new ones including two nor-sesquiterpene lactones and two dimeric lactones. The structures were elucidated by highfield (1)H-NMR spectroscopy. ...

journal_title：Planta medica

authors： Jakupovic J,Sun H,Geerts S,Bohlmann F

更新日期：1987-02-01 00:00:00

abstract：:The specific physiological responses induced by inhaling R-(-)- as well as S-(+)-linalool in 24 human subjects undergoing experimental stress were investigated in this study. Various physiological parameters of the autonomous nervous system (heart rate, blood pressure, electrodermal activity) as well as the endocrine ...

journal_title：Planta medica

authors： Höferl M,Krist S,Buchbauer G

更新日期：2006-10-01 00:00:00

abstract：:Reinvestigating the constituents of the roots of Vitis thunbergii Sieb. & Zucc. led to the isolation of three new resveratrol derivatives, vitisinols E-G (1-3), together with 14 known compounds. The structures of compounds 1-3 were established by application of spectroscopic analyses (NMR, MS, UV, and IR). ...

journal_title：Planta medica

authors： Chiou WF,Shen CC,Chen CC,Lin CH,Huang YL

更新日期：2009-06-01 00:00:00

abstract：:Two new phenolic glycosides characterized as idesin salicylate (1) and 2-hydroxyphenol-1-O-beta-D-glucopyranosyl-(6-->1)- alpha-L-rhamnopyranoside (2) were isolated with four known compounds, idescarpin (3), idesin (4), 1-hydroxy-6-oxocyclohex-2-enecarboxylic acid methyl ester (5) and salirepin (6), from the fruits of...

journal_title：Planta medica

authors： Kim SH,Jang YP,Sung SH,Kim YC

更新日期：2007-02-01 00:00:00

abstract：:The fruit of Ziziphus jujuba Mill., known as jujube or Chinese date, is commonly consumed as health supplement or herbal medicine worldwide. To study the beneficial role of jujube in enhancing hematopoietic function, we investigated its roles on the expression of erythropoietin in cultured Hep3B human hepatocellular c...

journal_title：Planta medica

authors： Chen J,Lam CT,Kong AY,Zhang WL,Zhan JY,Bi CW,Chan GK,Lam KY,Yao P,Dong TT,Tsim KW

更新日期：2014-11-01 00:00:00

abstract：:Biosynthetic pathways of the essential oil components in PERILLA FRUTESCENS were examined by tracer experiments using [ (14)C]-labeled sucrose on two chemotypes: perillaketone (PK) and phenylpropanoid (PP-EM) types. The results of the experiments indicated that perillaketone is not converted from isoegomaketone but is...

journal_title：Planta medica

authors： Nishizawa A,Honda G,Tabata M

更新日期：1989-06-01 00:00:00

abstract：:The configurations of the component amino acids in ginseng tetrapeptide 1 isolated from Panax ginseng were determined by HPLC with an optical resolution column and the structure of 1 was established to be H-L-Val-gamma-D-Glu-D-Arg- Gly-OH. Synthesis of the ginseng tetrapeptide, 1, and of the configuration and conjugat...

journal_title：Planta medica

authors： Yagi A,Ishizu T,Okamura N,Noguchi S,Itoh H

更新日期：1996-04-01 00:00:00

abstract：:A new strain of Claviceps was isolated from a blokked mutant of Claviceps purpurea. This strain accumulates substantial amounts of clavine alkaloids (2 g/l). The alkaloid fraction is composed of chanoclavine-I ( approximately 10%) and a mixture of agroclavine/elymoclavine (90%). Most suitable for alkaloid production i...

journal_title：Planta medica

authors： Schumann B,Erge D,Maier W,Gröger D

更新日期：1982-05-01 00:00:00

abstract：:Propionibacterium acnes, an anaerobic pathogen, plays an important role in the pathogenesis of acne and seems to initiate the inflammatory process by producing proinflammatory cytokines. In order to demonstrate the anti-inflammatory effects and action mechanisms of magnolol and honokiol, several methods were employed....

journal_title：Planta medica

authors： Lee J,Jung E,Park J,Jung K,Lee S,Hong S,Park J,Park E,Kim J,Park S,Park D

更新日期：2005-04-01 00:00:00

abstract：:The steam distilled oils both from flowers and leaves, as well as from total aerial parts of CHRYSANTHEMUM INDICUM L. (small-flowered form), were obtained and analyzed by GC and GC/MS. Their main components are borneol, chrysanthenone and bornyl acetate. ...

journal_title：Planta medica

authors： Stoianova-Ivanova B,Budzikiewicz H,Koumanova B,Tsoutsoulova A,Mladenova K,Brauner A

更新日期：1983-12-01 00:00:00

abstract：:The present study is aimed at evaluating the effects of luteolin on the scratching behavior associated with an allergic cutaneous reaction in mice. Elicitation of passive cutaneous anaphylaxis, and intradermal injections of compound 48/80, histamine or serotonin induced scratching behavior in ICR mice. Models of irrit...

journal_title：Planta medica

authors： Baolin L,Weiwei W,Ning T

更新日期：2005-05-01 00:00:00

abstract：:A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum....

journal_title：Planta medica

authors： Ahn KS,Sim WS,Lee IK,Seu YB,Kim IH

更新日期：1997-08-01 00:00:00

abstract：:This study evaluated the susceptibility of oral pathogenic microorganisms Candida albicans, Streptococcus mutans, Staphylococcus aureus, and Aggregatibacter actinomycetemcomitans to Brazilian medicinal plant extracts of Schinus terebinthifolius (aroeira), Croton campestris (velame), Lafoensia pacari (pacari), Centauri...

journal_title：Planta medica

authors： Pereira EM,Gomes RT,Freire NR,Aguiar EG,Brandão Md,Santos VR

更新日期：2011-03-01 00:00:00

abstract：:Vitex agnus-castus, the chaste tree, is used against disorders of the female sexual organs and as an anaphrodisiac. Active constituents are not known. In this study the essential oil of the fruits was investigated by GC and GC-MS. ...

journal_title：Planta medica

authors： Zwaving JH,Bos R

更新日期：1996-02-01 00:00:00

abstract：:The essential oils of Salvia ringens (samples A and B), were analyzed by means of GC and GC/MS. From the seventy-five identified constituents representing 99.82 and 99.86% of the oils, 1,8-cineole and alpha-pinene were the major components. Furthermore, sample B exhibited a very interesting antimicrobial profile after...

journal_title：Planta medica

authors： Tzakou O,Pitarokili D,Chinou IB,Harvala C

更新日期：2001-02-01 00:00:00

abstract：:Three new β-indoloquinazoline alkaloids, orirenierine A (1), B (2) and C (4), together with eleven known compounds were isolated from the methanol extract of the stems of Oricia renieri. The structures of all compounds were determined by comprehensive analyses of their spectroscopic data and comparison with literature...

journal_title：Planta medica

authors： Wansi JD,Happi EN,Bavoua JL,Devkota KP,Sewald N

更新日期：2012-01-01 00:00:00

abstract：:The roots of Cryptolepis sanguinolenta have been investigated for their chemical composition since 1931 but so far no studies on the leaves have been reported although they are used in traditional medicine in Guinea-Bissau. Two new alkaloids identified as cryptolepinoic acid (1) and methyl cryptolepinoate (2) and the ...

journal_title：Planta medica

authors： Paulo A,Gomes ET,Steele J,Warhurst DC,Houghton PJ

更新日期：2000-02-01 00:00:00

abstract：:Two new C(18) dibenzocyclooctadiene lignans named heteroclitalignans A and B (1 and 3), one new C(19) homolignan named heteroclitalignan C(4) and one new natural product named heteroclitalignan D(2), together with the four known lignans kadsurarin (5), kadsulignan E (6), d-epigalbacin, and meso-dihydroguaiaretic acid ...

journal_title：Planta medica

authors： Wang W,Liu J,Liu R,Xu Z,Yang M,Wang W,Liu P,Sabia G,Wang X,Guo D

更新日期：2006-02-01 00:00:00

abstract：:In previous studies, crude Houttuynia cordata polysaccharides showed beneficial effects on acute lung injury in vivo, a syndrome in which anti-complementary activities played an important role. Anti-complementary activity-guided fractionation of H. cordata polysaccharides led to the isolation of two highly branched ho...

journal_title：Planta medica

authors： Lu Y,Zhang JJ,Huo JY,Chen DF

更新日期：2019-09-01 00:00:00

abstract：:Echinacea purpurea cell cultures have been established for the production of secondary and possibly bioactive compounds using elicitation techniques. Different elicitors including yeast elicitor, methyl jasmonate, glutathione, and manganese ions were used and compared for their effects on the formation of phenolics in...

journal_title：Planta medica

authors： Li WW,Barz W

更新日期：2006-02-01 00:00:00

abstract：:The antioxidant effects of 1,5-anhydro-D-fructose (1,5-AF), a unique anhydrohexulose, were studied in 1,1-diphenyl-2-picrylhydrazyl (DPPH) solution, in human cells along with lipid peroxidation of low-density lipoprotein (LDL). We have confirmed that 1,5-AF scavenges DPPH radicals directly in solution and inhibits the...

journal_title：Planta medica

authors： Yamaji K,Sarker KP,Maruyama I,Hizukuri S

更新日期：2002-01-01 00:00:00

abstract：:The ripe berries of Harrisonia abyssinica yielded two new prenylated acetophenones, namely 5-(ethan-1'''-one)-4,6-dihydroxy-7-(3'',3''-dimethylallyl)-2 S-(1' S-hydroxy-1',5'-dimethylhex-4'-enyl)-2,3-dihydrobenzofuran (1) and 5-(2'''-hydroxyethan-1'''-one)-4,6-dihydroxy-7-(3'',3''-dimethylallyl)-2 S-(1' S-hydroxy-1',5'...

journal_title：Planta medica

authors： Mayaka RK,Langat MK,Omolo JO,Cheplogoi PK

更新日期：2012-03-01 00:00:00

abstract：:Activator protein 1 (AP-1) is a transcription factor which plays a critical role in inflammation and carcinogenesis. The present study was conducted to investigate the effect of berberine, an isoquinoline alkaloid present in plants of the genera Berberis and Coptis, on the activity of AP-1 using a reporter gene assay ...

journal_title：Planta medica

authors： Fukuda K,Hibiya Y,Mutoh M,Koshiji M,Akao S,Fujiwara H

更新日期：1999-05-01 00:00:00

abstract：:Stellera chamaejasme, also known as "Langdu", has been traditionally used for the management of skin-related diseases such as psoriasis and skin ulcers. The aim of this study was to determine whether S. chamaejasme and its major component, luteolin 7-O-glucoside, have a preventive effect on the development of atopic d...

journal_title：Planta medica

authors： Jo BG,Park NJ,Jegal J,Choi S,Lee SW,Yi LW,Kim SN,Yang MH

更新日期：2019-05-01 00:00:00

abstract：:The nature of gene action for biomass yield and tropane alkaloid content was ascertained through diallel analysis in Egyptian henbane, HYOSCYAMUS MUTICUS L. Dominance variation was preponderant over additive genetic variance, dominance being in the overdominance range for both traits. On an overall basis, recessive al...

journal_title：Planta medica

authors： Misra HO,Sharma JR,Lal RK

更新日期：1992-02-01 00:00:00

abstract：:This perspective describes some commonly used animal models for the evaluation of potential chemopreventive agents in colon carcinogenesis. Special emphasis is given to the azoxymethane (AOM)/1,2-dimethylhydrazine (DMH) rat model and APCMIN mice, carrying a mutation in APC, a key gene in human carcinogenesis. In the A...

journal_title：Planta medica

authors： Femia AP,Caderni G

更新日期：2008-10-01 00:00:00

abstract：:Two new depsides as well as the known p-hydroxybenzoic acid and its methyl ester, protocatechuic acid, 2-(4-hydroxyphenyl)-ethanol, 2-(3,4-dihydroxyphenyl)-ethanol and the flavonoids kaempferol, quercetin, luteolin and hypolaetin and the glycosides 3- O-beta- D-glucopyranosylquercetin (isoquercitrine), 3- O-beta- D-gl...

journal_title：Planta medica

authors： Hillenbrand M,Zapp J,Becker H

更新日期：2004-04-01 00:00:00

abstract：:It has been known that silymarin exhibits protective activity against oxidative liver injury induced by various hepatotoxicants, but the underlying mechanism of its beneficial action remains unclear. We determined the alterations in sulfur-containing amino acid metabolism induced by silymarin in association with its e...

journal_title：Planta medica

authors： Kwon DY,Jung YS,Kim SJ,Kim YS,Choi DW,Kim YC

更新日期：2013-08-01 00:00:00

abstract：:As part of our continuing study on the Calophyllum species, a number of coumarins, xanthones and chromene acids from different Calophyllum species of Sri Lanka were tested for inhibitory activity against the HIV-1 and its virally-encoded reverse transcriptase (RT). These compounds were found to be inactive in both the...

journal_title：Planta medica

authors： Dharmaratne HR,Tan GT,Marasinghe GP,Pezzuto JM

更新日期：2002-01-01 00:00:00

abstract：:There is an obvious discrepancy between the popularity of mistletoe extracts and their classification as a non-conventional treatment modality with unproven efficacy in oncology. The commercial preparations suffer from several major drawbacks: lack of precise declarations for the molecular characteristics and the conc...

journal_title：Planta medica

authors： Gabius HJ,Gabius S,Joshi SS,Koch B,Schroeder M,Manzke WM,Westerhausen M

更新日期：1994-02-01 00:00:00