Abstract:
:Two new compounds, methyl 3-chloro-6-hydroxy-2-(4-hydroxy-2-methoxy-6-methylphenoxy)-4-methoxybenzoate (1) and (2 S,5' R,E)-7-hydroxy-4,6-dimethoxy-2-(1-methoxy-3-oxo-5-methylhex-1-enyl)-benzofuran-3(2H)-one (2), together with four known compounds, griseofulvin (3), dechlorogriseofulvin (4), bostrycin (5), and deoxybostrycin (6), were isolated from the marine endophytic fungus NIGROSPORA sp. (No. 1403) collected from the South China Sea. The structures were elucidated by spectroscopic methods, 1D, 2D NMR, and HREIMS. Compounds 5 and 6 showed moderate antitumor and moderate antimicrobial activity.
journal_name
Planta Medjournal_title
Planta medicaauthors
Xia X,Li Q,Li J,Shao C,Zhang J,Zhang Y,Liu X,Lin Y,Liu C,She Zdoi
10.1055/s-0030-1271040subject
Has Abstractpub_date
2011-10-01 00:00:00pages
1735-8issue
15eissn
0032-0943issn
1439-0221journal_volume
77pub_type
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