Inhibitory activity of stilbenes from medicinal plants on the expression of cell adhesion molecules on THP1 cells.

Abstract:

:The inhibitory activity of stilbenes isolated from medicinal plants on cell adhesion molecules on the surface of THP-1 human monocytic cell lines was investigated. Among ten stilbenes tested, four stilbenes displayed a significant inhibitory activity on the expression of both intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1). A cell-to-cell adhesion assay showed that 3,5-dihydroxy-4'-methoxystilbene and 2,3,4',5-tetrahydroxystilbene-2-O-beta-D-glucopyranoside as well as resveratrol blocked significantly TNF-alpha-inducing cell-cell adhesion between human umbilical vein endothelial cells (HUVEC) and THP-1 cells.

journal_name

Planta Med

journal_title

Planta medica

authors

Ahn KS,Kim JH,Oh SR,Ryu SY,Lee HK

doi

10.1055/s-2000-8634

subject

Has Abstract

pub_date

2000-10-01 00:00:00

pages

641-4

issue

7

eissn

0032-0943

issn

1439-0221

journal_volume

66

pub_type

信件
  • Guaianolides from Lactuca saligna.

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  • Purification and biochemical characterization of a novel allergenic protein from tatary buckwheat seeds.

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  • Marine natural products research: current directions and future potential.

    abstract::Natural products research is increasingly turning to marine animals, plants, and microbes as source organisms. Several marine natural products are currently in preclinical and clinical evaluation, others show promising biological activities in in vitro and in vivo assays. Investigations of biological and chemical ecol...

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  • Bisbenzylisoquinoline alkaloids from the roots of cyclea tonkinensis.

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    更新日期:2006-02-01 00:00:00

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    abstract::From stem barks of Isolona guesquiereina three known bisbenzylisoquinolines were isolated and identified as (-)-curine, chondrofoline and isochondodendrine. Structures were established mainly on the basis of comparison of their physical and spectral data with published data for them and their methylated derivatives. C...

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    authors: Mambu L,Martin MT,Razafimahefa D,Ramanitrahasimbola D,Rasoanaivo P,Frappier F

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  • Inhibitory activity of soyasaponin II on virus replication in vitro.

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  • Antitumoral Activity of (20R)- and (20S)-Ginsenoside Rh2 on Transplanted Hepatocellular Carcinoma in Mice.

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  • Antifungal chromans inhibiting the mitochondrial respiratory chain of pea seeds and new xanthones from Calophyllum caledonicum.

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  • Cardioprotection and matrix metalloproteinase-9 regulation of salvianolic acids on myocardial infarction in rats.

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  • Plant-derived leading compounds for chemotherapy of human immunodeficiency virus (HIV) infection - an update (1998 - 2007).

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    doi:10.1055/s-2008-1081314

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    更新日期:2008-09-01 00:00:00

  • Protodioscin (NSC-698 796): its spectrum of cytotoxicity against sixty human cancer cell lines in an anticancer drug screen panel.

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  • Hydroxytyrosol induces vascular smooth muscle cells apoptosis through NO production and PP2A activation with subsequent inactivation of Akt.

    abstract::Olive oil has been shown to exhibit beneficial effects in the prevention of cardiovascular diseases although its molecular mechanism still remains unclear. In the present study, we investigated the effect of hydroxytyrosol (HT), a major phenolic component in olive oil and leaves from OLEA EUROPAEA L. (Oleaceae family...

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    pub_type: 杂志文章

    doi:10.1055/s-0030-1271073

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  • Medicinal Plants from Papua New Guinea: Graniline-Esters and Germacranolides from Blumea arfakiana.

    abstract::From the leaves of BLUMEA ARFAKIANA Martelli (Asteraceae), used in traditional medicine in Papua New Guinea, besides stigmasterol and beta-eudesmol, four graniline esters ( 1-4) have been isolated. Furthermore, blumealactone C ( 5), deacetylblumealactone C ( 6), and deoxyblumealactone C ( 7) have been identified. ...

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  • Nano-Pelargonidin Protects Hyperglycemic-Induced L6 Cells against Mitochondrial Dysfunction.

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    更新日期:2014-06-01 00:00:00

  • Micropropagation of Hydrastis canadensis: Goldenseal a North American endangered species.

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  • [Barbatoside, a new Iridoid glucoside from Penstemon barbatus].

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    pub_type: 杂志文章

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  • Effects of the olive tree leaf constituents on myocardial oxidative damage and atherosclerosis.

    abstract::The olive (Olea europaea) leaf is considered an important traditional herbal medicine utilized against infectious diseases, and for the treatment of diabetes and hypertension. Moreover, olive leaf constituents have been related to cardioprotection, probably due to their association with cellular redox modulating effec...

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    pub_type: 杂志文章,评审

    doi:10.1055/s-0035-1546017

    authors: Efentakis P,Iliodromitis EK,Mikros E,Papachristodoulou A,Dagres N,Skaltsounis AL,Andreadou I

    更新日期:2015-06-01 00:00:00

  • Leaf alkaloid contents of Tabernaemontana pachysiphon as influenced by endogenous and environmental factors in the natural habitat.

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    pub_type: 杂志文章

    doi:10.1055/s-2006-957393

    authors: Höft M,Verpoorte R,Beck E

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  • Inhibitory effects of the essential oil of Mentha pulegium on the isolated rat myometrium.

    abstract::The effects of the essential oil of Mentha pulegium L. (EOMP), a plant commonly known as "pennyroyal" or "poejo" that is used in folk medicine as an abortifaceant, were assessed on the isolated rat myometrium. Myometrial strips were stimulated with 10 nM oxytocin or 10 microM PGF (2alpha). EOMP (10 - 300 microg/mL) co...

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    pub_type: 杂志文章

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    authors: Soares PM,Assreuy AM,Souza EP,Lima RF,Silva TO,Fontenele SR,Criddle DN

    更新日期:2005-03-01 00:00:00