Abstract:
:A method was developed to distinguish Vaccinium species based on leaf extracts using nuclear magnetic resonance spectroscopy. Reference spectra were measured on leaf extracts from several species, including lowbush blueberry (Vaccinium angustifolium), oval leaf huckleberry (Vaccinium ovalifolium), and cranberry (Vaccinium macrocarpon). Using principal component analysis, these leaf extracts were resolved in the scores plot. Analysis of variance statistical tests demonstrated that the three groups differ significantly on PC2, establishing that the three species can be distinguished by nuclear magnetic resonance. Soft independent modeling of class analogies models for each species also showed discrimination between species. To demonstrate the robustness of nuclear magnetic resonance spectroscopy for botanical identification, spectra of a sample of lowbush blueberry leaf extract were measured at five different sites, with different field strengths (600 versus 700 MHz), different probe types (cryogenic versus room temperature probes), different sample diameters (1.7 mm versus 5 mm), and different consoles (Avance I versus Avance III). Each laboratory independently demonstrated the linearity of their NMR measurements by acquiring a standard curve for chlorogenic acid (R(2) = 0.9782 to 0.9998). Spectra acquired on different spectrometers at different sites classifed into the expected group for the Vaccinium spp., confirming the utility of the method to distinguish Vaccinium species and demonstrating nuclear magnetic resonance fingerprinting for material validation of a natural health product.
journal_name
Planta Medjournal_title
Planta medicaauthors
Markus MA,Ferrier J,Luchsinger SM,Yuk J,Cuerrier A,Balick MJ,Hicks JM,Killday KB,Kirby CW,Berrue F,Kerr RG,Knagge K,Gödecke T,Ramirez BE,Lankin DC,Pauli GF,Burton I,Karakach TK,Arnason JT,Colson KLdoi
10.1055/s-0034-1368569subject
Has Abstractpub_date
2014-06-01 00:00:00pages
732-9issue
8-9eissn
0032-0943issn
1439-0221journal_volume
80pub_type
杂志文章相关文献
PLANTA MEDICA文献大全abstract::Three new steroidal saponins were isolated from the fruits of Tribulus terrestris, and their structures were elucidated as (25R,S)-5 alpha-spirostane-12-one-3 beta-ol-3-O-beta-xylopyranosyl(1-->2)- [beta-xylopyranosyl(1-->3)]-beta-glucopyranosyl(1-->4)-[alpha-rhamno- pyranosyl(1-->2)]-beta-galactopyranoside; 26-O-beta...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-11650
更新日期:2001-03-01 00:00:00
abstract::Acute myocardial infarction (AMI) remains the leading cause of mortality in the world. Early intervention using salvianolic acids (SA) can substantially improve clinical outcomes. However, in spite of the great achievements that have been made in elucidating the protective effects of SA on AMI, the effects of SA on th...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185669
更新日期:2009-10-01 00:00:00
abstract::This study aimed to elucidate the mechanisms of nuciferine (a main aporphine alkaloid of lotus leaf extract), which can induce relaxation in contracted tracheal rings. Under Ca2+-free and 2 mM Ca2+ conditions, we found that nuciferine had no effect on the resting muscle tone of tracheal rings. In contrast, nuciferine ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-118178
更新日期:2018-01-01 00:00:00
abstract::Activity-guided fractionation of the dichloromethane extract from leaves of Piper fulvescens, using an agar overlay bioautographic method, led to the isolation of three antifungal neolignans identified as conocarpan, eupomatenoid 5 and eupomatenoid 6. The minimal inhibitory concentration of these three neolignans agai...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-18838
更新日期:2001-12-01 00:00:00
abstract::Cordatolide A and B were re-isolated from Calophyllum cordato-oblongum, an endemic species of Sri Lanka, and found to inhibit HIV-1 reverse transcriptase with IC50 values of 12.3 and 19.0 microM, respectively. ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-957483
更新日期:1998-06-01 00:00:00
abstract::HPLC determinations of the aescin contents in calli and embryoids from leaf explants of AESCULUS HIPPOCASTANUM L. were carried out in order to determine whether it was possible to obtain aescin-forming proliferations IN VITRO. The results indicate that embryogenic calli and embryoids derived from them produce an amoun...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960016
更新日期:1991-02-01 00:00:00
abstract::Orosunol and 8-demethylorosunol, two new 1-aryl-2,3-naphthalide lignans, have been isolated from Justicia flava root. Structures IV and V respectively have been proposed for them by spectral (UV, IR, PMR, (13)C NMR, and MS) and chemical evidence. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-971427
更新日期:1982-03-01 00:00:00
abstract::Hyperuricemia is a clinical condition characterized by an elevated level of serum uric acid and is a key risk factor for the development of gout and metabolic disorders. The existing urate-lowering therapies are often impractical for certain patient populations, providing a rationale to explore new agents with improve...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-111012
更新日期:2017-11-01 00:00:00
abstract::The inhibitory effect of flavonoids and phenolic acids, which could be transformed from flavonoids by human intestinal microflora, on the growth of Helicobacter pylori (HP) was investigated. Ponciretin, hesperetin, naringenin and diosmetin were active against HP. Among them, ponciretin was the most potent and its MIC ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-960805
更新日期:1999-06-01 00:00:00
abstract::An Alkanna orientalis leaf and flower extract inhibited the growth of Staphylococcus aureus, a pathogen that causes an estimated 478 000 hospitalizations in the US annually. Bioassay-guided fractionation of A. orientalis resulted in isolation of the flavonoid sarothrin (5,7,4'-trihydroxy-3,6,8-trimethoxyflavone), whic...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1328259
更新日期:2013-03-01 00:00:00
abstract::Two new triterpenoid saponins, along with five known ones, were isolated from the EtOH extract of the whole plants of Androsace umbellata. The structures of the new triterpenoid saponins were identified as 3- O-[ beta- D-xylopyranosyl-(1-->2)- beta- D-glucopyranosyl-(1-->4)-[ beta- D-glucopyranosyl-(1-->2)]- alpha- L-...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1081291
更新日期:2008-08-01 00:00:00
abstract::In our ongoing efforts to identify effective naturally sourced agents for the treating of diabetic complications, two new (1 and 2) and 11 known phenolic compounds (3-13) were isolated from an 80 % ethanol extract of Litsea japonica leaves. The structures of the new compounds were established by spectroscopic and chem...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0042-116324
更新日期:2017-02-01 00:00:00
abstract::In this study we examined the ability of the furofuran lignan yangambin to influence the local and systemic responses induced by antigen or PAF in actively sensitized or normal rats. Given intraperitoneally 1 h before stimulation, yangambin inhibited the pleural neutrophil and eosinophil infiltration evoked by the i.p...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957654
更新日期:1997-06-01 00:00:00
abstract::Five new compounds (1-5), including two limonoids, one triterpenoid, one steroid, and one sesquiterpenoid, along with nine known limonoids (6-14), were isolated from the bark of Melia azedarach. The structures of the new compounds were elucidated by 2D NMR spectroscopy and mass spectrometry. The isolated compounds as ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1328069
更新日期:2013-01-01 00:00:00
abstract::Bioactivity-guided fractionations for ACAT inhibitor led to the isolation of guineensine from the CHCl (3) extract of Piper longum. Its structure was identified by spectroscopic means (IR, UV, MS and NMR). Guineensine inhibited ACAT activity in a dose-dependent manner with an IC (50) value of 3.12 micro M. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2004-827193
更新日期:2004-07-01 00:00:00
abstract::A systematic structure-activity relationship of 3beta-hydroxy-27- P- E-coumaroyloxyurs-12-en-28-oic acid ( 7), a triterpene ester isolated from UNCARIA RHYNCHOPHYLLA as a phospholipase Cgamma1 inhibitor, was undertaken with a view toward elucidating its chemical mode of action on PLCgamma1. Related derivatives and ana...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1081348
更新日期:2008-10-01 00:00:00
abstract::Epilobium sp. are commonly used in traditional medicine in the treatment of early stages of benign prostatic hyperplasia and inflammation. It is suggested that a dominating constituent, oenothein B, is responsible for the extracts therapeutic effects. Several bioactivities were established for extracts and oenothein B...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-109372
更新日期:2017-10-01 00:00:00
abstract::Three new β-indoloquinazoline alkaloids, orirenierine A (1), B (2) and C (4), together with eleven known compounds were isolated from the methanol extract of the stems of Oricia renieri. The structures of all compounds were determined by comprehensive analyses of their spectroscopic data and comparison with literature...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0031-1280227
更新日期:2012-01-01 00:00:00
abstract::In natural product research, the isolation of biomarkers or bioactive compounds from complex natural extracts represents an essential step for de novo identification and bioactivity assessment. When pure natural products have to be obtained in milligram quantities, the chromatographic steps are generally labourious an...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0035-1545912
更新日期:2015-11-01 00:00:00
abstract::From the fresh, undried, and uncrushed leaves of NERIUM OLEANDER a new triterpenoid, kanerocin, has been isolated along with known ursolic and oleanolic acids and its structure established through chemical and spectroscopic methods as 3alpha-hydroxy-urs-18,20-dien-28-oic acid. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-962009
更新日期:1989-06-01 00:00:00
abstract::Three new coumarin derivatives, compounds 1-3, three new furanocoumarins, compounds 4-6, and a novel dioxocane derivative, compound 7, were isolated from the fern Cyclosorus interruptus (Willd.) H. Itô. Based on spectrometric and spectroscopic analysis (FAB or El mass spectrometry as well as 1D and 2D NMR experiments)...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2000-9908
更新日期:2000-12-01 00:00:00
abstract::Besides the known pyrrolidine alkaloids ruspolinone ( 1), norruspolinone ( 2), and norruspoline ( 3) the "bispyrrolidine" alkaloid hypercratine was isolated from the roots of RUSPOLIA HYPERCRATERIFORMIS M. R. (Acanthaceae). After chemical and spectroscopic analysis of the new compound, structure 4 is suggested. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969927
更新日期:1983-08-01 00:00:00
abstract::According to traditional usage, the extract of Longan Arillus was tested for its anxiolytic-like effect by application of the Vogel-type anti-conflict method in mice. The extract indicated significant activity at a dose of 2 g/kg, s.c., and results of the bioassay-oriented isolation revealed adenosine to be the active...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-1999-14055
更新日期:1999-03-01 00:00:00
abstract::A plant mixture containing extracts of Nigella sativa possesses blood glucose lowering effects, but the direct antidiabetic effect of Nigella sativa is not yet established. Therefore, the effect of Nigella sativa oil (NSO) on blood glucose concentrations was studied in streptozotocin diabetic rats. In addition, the ef...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-32084
更新日期:2002-05-01 00:00:00
abstract::Flavonolignan compounds have been isolated from the fruits of SILYBUM MARIANUM subsp. ANATOLICUM and kaempferol 3-sulphate and other flavonoid compounds have been isolated from the aerial parts and were identified. The flavonoid sulphate derivatives are shown to be present in SILYBUM genus for the first time. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-962330
更新日期:1988-02-01 00:00:00
abstract::Bioassay-guided fractionation of the anti-HIV-1 active EtOAc extract from leaves and twigs of Ochna integerrima led to the isolation of five new flavonoid glycosides 1 - 5, five known flavonoids 6 - 10, and two known flavonoid glycosides 11 and 12. Structures were determined based on spectroscopic analyses. 6- gamma, ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-981538
更新日期:2007-06-01 00:00:00
abstract::Tissue callus cultures originating from CHELIDONIUM MAJUS L. seeds were established on Gamborg B5, Murashige-Skoog (MS), and Schenk-Hildebrandt (SH) media. In all experimental conditions, calli accumulated a complex pattern of isoquinoline derivatives. The highest values, both in growth and in sanguinarine production,...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960141
更新日期:1991-10-01 00:00:00
abstract::The leaves of Myrcia ovata, popularly known as "laranjinha do mato", are frequently used as an infusion in folk medicine. The essential oil obtained from these leaves is rich in citral, a mixture of neral and geranial isomers, known for its analgesic effect. Male Swiss mice (20-22 g) were tested in models of acute pai...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0034-1383120
更新日期:2014-11-01 00:00:00
abstract::In our ongoing research into anti-inflammatory compounds from Tanacetum microphyllum, four naturally occurring flavonoids (santin, ermanin, centaureidin and 5,3'-dihydroxy-4'-methoxy-7-methoxycarbonylflavonol) and one sesquiterpene lactone (hydroxyachillin) isolated from this plant, were evaluated as potential inhibit...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2004-815452
更新日期:2004-01-01 00:00:00
abstract::Three new compounds, namely, (+)-dihydrodehydrodiconiferyl alcohol 4- O- beta-(6''- O-galloyl)-glucopyranoside ( 1), 4,4'- O-dimethylellagic acid 3-(2''- O-acetyl)- alpha-rhamnopyranoside ( 2), and ethyl O- beta-(6'-galloyl)-glucopyranoside ( 3), together with eleven known ones, were isolated from the stem bark of Tre...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034361
更新日期:2008-03-01 00:00:00