Abstract:
:Three new compounds, namely, (+)-dihydrodehydrodiconiferyl alcohol 4- O- beta-(6''- O-galloyl)-glucopyranoside ( 1), 4,4'- O-dimethylellagic acid 3-(2''- O-acetyl)- alpha-rhamnopyranoside ( 2), and ethyl O- beta-(6'-galloyl)-glucopyranoside ( 3), together with eleven known ones, were isolated from the stem bark of Trewia nudiflora. Their structures were elucidated by means of 1D, 2 D NMR and HR-MS analyses. The antioxidant activities of these compounds were evaluated with the DPPH radical-scavenging assay. Compound 1 showed significant antioxidant activity. In addition, compounds 1, 2 and 3 rescued the H (2)O (2)-induced PC12 cell death at 0.4 microM in the MTT assay.
journal_name
Planta Medjournal_title
Planta medicaauthors
Kang QJ,Yang XW,Wu SH,Ma YL,Li L,Shen YMdoi
10.1055/s-2008-1034361subject
Has Abstractpub_date
2008-03-01 00:00:00pages
445-8issue
4eissn
0032-0943issn
1439-0221journal_volume
74pub_type
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