Abstract:
:Calozeyloxanthone ( 1) was re-isolated from the root bark of Calophyllum moonii, an endemic species of Sri Lanka, and found to be active against vancomycin-resistant Enterococci (VRE) and vancomycin-sensitive Enterococci (VSE) with MIC values of 6.25 microg/ml and 12.5 microg/ml, respectively. Further, a marked synergism between 1 and vancomycin hydrochloride (VCM) against VRE was also observed. These findings suggest that 1 in combination with VCM against VRE may be useful in controlling VRE infections.
journal_name
Planta Medjournal_title
Planta medicaauthors
Sakagami Y,Kajimura K,Wijesinghe WM,Dharmaratne HRdoi
10.1055/s-2002-32558subject
Has Abstractpub_date
2002-06-01 00:00:00pages
541-3issue
6eissn
0032-0943issn
1439-0221journal_volume
68pub_type
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