Diarylheptanoids from Alnus glutinosa bark and their chemoprotective effect on human lymphocytes DNA.

abstract：:Citral, 3,7-dimethyl-2,6-octadien-1-al, a key component of the lemon-scented essential oils extracted from several herbal plants such as lemon grass (Cymbopogon citratus), melissa (Melissa officinalis), verbena (Verbena officinalis) is used as a food additive and as a fragrance in cosmetics. In this study, we investig...

journal_title：Planta medica

authors： Dudai N,Weinstein Y,Krup M,Rabinski T,Ofir R

更新日期：2005-05-01 00:00:00

abstract：:Two new protopine-type alkaloids, argemexicaine A (1) and argemexicaine B (2), along with thirteen known alkaloids, were isolated from MeOH extracts of Formosan Argemone mexicana L. (Papaveraceae). Physical and spectral analyses, particularly IR and thermo-modulated 1D and 2D NMR, were used to determine the transannul...

journal_title：Planta medica

authors： Chang YC,Hsieh PW,Chang FR,Wu RR,Liaw CC,Lee KH,Wu YC

更新日期：2003-02-01 00:00:00

abstract：:Amphotericin B (AmB) is a representative antibiotic for the control of serious fungal infections, and its fungicidal activity was greatly enhanced by allicin, an allyl-sulfur compound from garlic. In addition to the plasma membrane permeability change, AmB induced vacuole membrane damage so that the organelles were vi...

journal_title：Planta medica

authors： Ogita A,Fujita K,Taniguchi M,Tanaka T

更新日期：2006-10-01 00:00:00

abstract：:This Paper describes an improved HPLC method for the determination of pentacyclic oxindole alkaloids in Uncaria tomentosa (Cat's Claw). Six of the isomeric compounds could be baseline separated at room temperature within less than 30 min by using 3 microm C-18 column material and a mobile phase consisting of 10 mM pho...

journal_title：Planta medica

authors： Ganzera M,Muhammad I,Khan RA,Khan IA

更新日期：2001-07-01 00:00:00

abstract：:Astilbin, a flavonoid compound, was isolated from the rhizome of Smilax glabra Roxb. This study was conducted to investigate the efficacy of astilbin on experimental diabetic nephropathy (DN) in vivo and in vitro and its possible mechanisms. Astilbin was added in high glucose stimulated HK-2 cells, streptozotocin-indu...

journal_title：Planta medica

authors： Li GS,Jiang WL,Yue XD,Qu GW,Tian JW,Wu J,Fu FH

更新日期：2009-11-01 00:00:00

abstract：:Isoliquiritigenin (4,2',4'-trihydroxychalcone, ISL) is a natural pigment with a simple chalcone structure. In this study, we report the ISL-induced inhibition on the growth of human hepatoma cells (Hep G2) for the first time. The cell growth inhibition achieved by ISL treatment resulted in programmed cell death in a c...

journal_title：Planta medica

authors： Hsu YL,Kuo PL,Lin LT,Lin CC

更新日期：2005-02-01 00:00:00

abstract：:In Brazil, Plectranthus species are known as "boldo" and have been used in popular medicine for analgesic and dyspeptic purposes. Plectranthus need to be well identified in order to be used as commercially genuine medicinal plants. Here we describe AFLP DNA patterns able to distinguish among different Pectranthus spec...

journal_title：Planta medica

authors： Passinho-Soares H,Felix D,Kaplan MA,Margis-Pinheiro M,Margis R

更新日期：2006-08-01 00:00:00

abstract：:The medicinal properties of curcumin obtained from Curcuma longa L. cannot be utilised because of poor bioavailability due to its rapid metabolism in the liver and intestinal wall. In this study, the effect of combining piperine, a known inhibitor of hepatic and intestinal glucuronidation, was evaluated on the bioavai...

journal_title：Planta medica

authors： Shoba G,Joy D,Joseph T,Majeed M,Rajendran R,Srinivas PS

更新日期：1998-05-01 00:00:00

abstract：:Jujuboside A (JuA) is a glycoside extracted from the seed of Ziziphus jujuba Mill var. spinosa (Bunge) Hu ex H F Chou, a Chinese herbal medicine, which has long been known as a sedative-hypnotic drug. The present study used the method of intracerebroventricular (i.c.v.) JuA in vivo to detect the effect of JuA on paire...

journal_title：Planta medica

authors： Shou C,Feng Z,Wang J,Zheng X

更新日期：2002-09-01 00:00:00

abstract：:The quantification of free and total alkannins in 13 endemic Anatolian Alkanna species is described for the first time. Extraction of the samples was performed by sonication with hexane, followed by hydrolysis in 1 N NaOH. For analysis, a new HPLC method, utilizing reversed phase material (Synergi Max RP), was develop...

journal_title：Planta medica

authors： Pekin G,Ganzera M,Senol S,Bedir E,Korkmaz KS,Stuppner H

更新日期：2007-03-01 00:00:00

abstract：:This perspective describes some commonly used animal models for the evaluation of potential chemopreventive agents in colon carcinogenesis. Special emphasis is given to the azoxymethane (AOM)/1,2-dimethylhydrazine (DMH) rat model and APCMIN mice, carrying a mutation in APC, a key gene in human carcinogenesis. In the A...

journal_title：Planta medica

authors： Femia AP,Caderni G

更新日期：2008-10-01 00:00:00

abstract：:Phytochemical investigation of the ethyl acetate extract from the aerial parts of Eryngium triquetrum Vahl resulted in the isolation of new polyacetylenes, triquetridiol (6) and trans-epoxy-triquetrol (7a/7b, diastereomeric mixture), and the lignan demethoxy carolignan Z (8a/8b, erythro/threo pair), together with a se...

journal_title：Planta medica

authors： Bouzergoune F,Ciavatta ML,Bitam F,Carbone M,Aberkane MC,Gavagnin M

更新日期：2016-11-01 00:00:00

abstract：:Three new xanthones, 22,23-dihydroxydihydrogambogenic acid (1), 12-hydroxygambogefic acid A (2), and hanburixanthone (3), along with thirteen known compounds were isolated from the resin of Garcinia hanburyi. The structures of the new compounds were determined by detailed analysis of 1D and 2D NMR spectra and by compa...

journal_title：Planta medica

authors： Deng YX,Guo T,Shao ZY,Xie H,Pan SL

更新日期：2013-06-01 00:00:00

abstract：:The traditional analgesic and antipyretic Ethiopian drug "Dingetegna" is made of dried root material of Taverniera abyssinica A. Rich (Leguminosae). In a screening for nematicidal natural products, "Dingetegna" extracts showed strong nematicidal activities towards C. elegans. In the following, medicarpin and 4-hydroxy...

journal_title：Planta medica

authors： Stadler M,Dagne E,Anke H

更新日期：1994-12-01 00:00:00

abstract：:When added to suspension cultures of CATHARANTHUS ROSEUS, abscisic acid (ABA) stimulated intracellular accumulation of the indole alkaloids catharanthine and ajmalicine in both flask and 30 litre fermenter-scale systems. The response varied, and depended upon the cell line, the concentration and source of the ABA, and...

journal_title：Planta medica

authors： Smith JI,Smart NJ,Kurz WG,Misawa M

更新日期：1987-10-01 00:00:00

abstract：:Scientific achievements in the last two decades have revolutionized the treatment and prevention of breast cancer. This is mainly because of targeted therapies and a better understanding of the relationship between estrogen, its receptor, and breast cancer. One of these discoveries is the use of synthetic selective es...

journal_title：Planta medica

authors： Oseni T,Patel R,Pyle J,Jordan VC

更新日期：2008-10-01 00:00:00

abstract：:Callus induction starting from the rhizome tissue of plants of three CURCUMA species: CURCUMA ZEDOARIA Roscoe, C. DOMESTICA Valeton, and C. AROMATICA Salisbury (Zingiberaceae) was performed. Successful callus formation was obtained in all three species using Murashige-Skoog's (MS) medium supplemented with 1-naphthalen...

journal_title：Planta medica

authors： Yasuda K,Tsuda T,Shimizu H,Sugaya A

更新日期：1988-02-01 00:00:00

abstract：:Andrographolide (Andro) is a potentially anti-inflammatory diterpenoid lactone isolated from the traditional herbal medicine ANDROGRAPHIS PANICULATA, which has been effectively used for the treatment of infection, inflammation, cold, fever and diarrhea in China for centuries. In the current study, we found that Andro ...

journal_title：Planta medica

authors： Ji L,Liu T,Liu J,Chen Y,Wang Z

更新日期：2007-10-01 00:00:00

abstract：:From the methanolic extract of the whole plants of Bidens pilosa the new beta-D-glucopyranosyloxy-3-hydroxy-6(E)-tetradecen-8, 10,12-triyne besides a known polyine has been isolated and identified mainly by IR and NMR methods. The new compound showed overgrowing action against normal and transformed human cell lines i...

journal_title：Planta medica

authors： Alvarez L,Marquina S,Villarreal ML,Alonso D,Aranda E,Delgado G

更新日期：1996-08-01 00:00:00

abstract：:Using exhaustive chromatographic separation we have isolated (-)-tigloyl-deangeloyl-gomisin F as a novel dibenzocyclooctadiene lignan from schisandra chinensis. With the help of HPLC, we further isolated (+)-schisandrin, (+)-deoxyschisandrin, (+)-γ-schisandrin, (-)-gomisin J, (+)-gomisin A, (-)-gomisin N, (-)-tigloyl-...

journal_title：Planta medica

authors： Smejkal K,Slapetová T,Krmenčík P,Babula P,Dall'Acqua S,Innocenti G,Vančo J,Casarin E,Carrara M,Kalvarová K,Dvorská M,Slanina J,Kramářová E,Julínek O,Urbanová M

更新日期：2010-10-01 00:00:00

abstract：:We identified eight diterpenes from Cryptomeria japonica (Taxodiaceae), which inhibit the activity of the androgen receptor (AR) in human prostate cancer (PCa) 22Rv1-derived 103E cells. The compounds 6,12-dihydroxyabieta-5,8,11,13-tetraen-7-one ( 2), sugiol ( 3), ferruginol ( 4), and 5-epixanthoperol ( 7) have near 10...

journal_title：Planta medica

authors： Tu WC,Wang SY,Chien SC,Lin FM,Chen LR,Chiu CY,Hsiao PW

更新日期：2007-10-01 00:00:00

abstract：:In our investigation of in vitro antimalarial screening of medicinal herbal extracts, the n-BuOH extract from the root of Wikstroemia indica showed a potent inhibitory effect. Fractionation of the active extract led to the isolation of two biflavonoids, sikokianin B ( 1) and sikokianin C ( 2) with IC (50) values 0.54 ...

journal_title：Planta medica

authors： Nunome S,Ishiyama A,Kobayashi M,Otoguro K,Kiyohara H,Yamada H,Omura S

更新日期：2004-01-01 00:00:00

abstract：:A total of 37 commercial samples of Ginseng Radix, the origins of which belonged to Panax ginseng C. A. Meyer, P. quinquefolia Linn. (American ginseng), and P. notoginseng Burkill (sanchi-ginseng), respectively, were collected from the Taiwan herbal markets. The contents of nine ginsenosides, Rb(1), Rb(2), Rc, Rd, Re,...

journal_title：Planta medica

authors： Chuang WC,Wu HK,Sheu SJ,Chiou SH,Chang HC,Chen YP

更新日期：1995-10-01 00:00:00

abstract：:Seven coumarins were isolated from the aerial parts of Tordylium apulum; their structures were established by spectroscopic means. All compounds were tested in vitro for their cytotoxicity against two cell line systems. The antiproliferative effects for three of them were studied at the level of the cell cycle in asyn...

journal_title：Planta medica

authors： Kofinas C,Chinou I,Loukis A,Harvala C,Roussakis C,Maillard M,Hostettmann K

更新日期：1998-03-01 00:00:00

abstract：:Acute myocardial infarction (AMI) remains the leading cause of mortality in the world. Early intervention using salvianolic acids (SA) can substantially improve clinical outcomes. However, in spite of the great achievements that have been made in elucidating the protective effects of SA on AMI, the effects of SA on th...

journal_title：Planta medica

authors： Jiang B,Wu W,Li M,Xu L,Sun K,Yang M,Guan S,Liu X,Guo DA

更新日期：2009-10-01 00:00:00

abstract：:Chemical investigation of the stems of Casearia velutina led to the isolation and structural elucidation of three new acylated glycosides, casearicosides A-C (1-3), together with 13 known compounds. The structures of the new compounds were established by spectroscopic and chemical methods. These isolates were evaluate...

journal_title：Planta medica

authors： Chai XY,Li FF,Bai CC,Xu ZR,Shi HM,Tu PF

更新日期：2010-01-01 00:00:00

abstract：:Four diterpenoids, carnosic acid (1), carnosol (2), rosmanol (3), and epirosmanol (4), were isolated as antioxidative agents from the leaves of Rosmarinus officinalis by bioassay-directed fractionation. These diterpenoids inhibited superoxide anion production in the xanthine/xanthine oxidase system. Mitochondrial and ...

journal_title：Planta medica

authors： Haraguchi H,Saito T,Okamura N,Yagi A

更新日期：1995-08-01 00:00:00

abstract：:Stabilization of growth factors in a wound environment is critical to the wound healing process. Here we report on the stabilization of key growth factors by a unique plant cell wall biomaterial. MicroSheets are clear cell wall fragments isolated from the non-living water storage cells in the pulp or inner gel of Aloe...

journal_title：Planta medica

authors： Ni Y,Turner D,Yates K,Tizard I

更新日期：2007-10-01 00:00:00

abstract：:The mechanism of action, leakage of cytochrome c from mitochondria into cytosol, for the antineoplastic compound glyfoline was examined. Additionally, our current studies revealed that glyfoline induced apoptotic changes and arrested cell cycle procession at the G2/M phase in nasopharyngeal carcinoma (NPC). A reverse ...

journal_title：Planta medica

authors： Su TL,Huang HM,Wang CK,Wu HC,Lin CT

更新日期：2005-01-01 00:00:00

abstract：:Recently, an increasing number of pharmacists had to supply medicinal products based on Cannabis sativa L. (Cannabaceae), prescribed by physicians to individual patients. Cannabis olive oil preparation is the first choice as a concentrated extract of cannabinoids, even though standardized operative conditions for obta...

journal_title：Planta medica

authors： Casiraghi A,Roda G,Casagni E,Cristina C,Musazzi UM,Franzè S,Rocco P,Giuliani C,Fico G,Minghetti P,Gambaro V

更新日期：2018-03-01 00:00:00