Bioactive coumarin derivatives from the fern Cyclosorus interruptus.

abstract：:The evidence for loss of Ca2+ homeostasis due to neuronal degeneration is considerable and rapidly increasing. In this study, we try to evaluate the protective effect of tetrandrine (TET), an alkaloid isolated from the Chinese medicinal herb Radix Stephania tetrandrae S., on amyloid-beta protein (Abeta) and 1-methyl-4...

journal_title：Planta medica

authors： Chiou WF,Lee WS,Yeh PH

更新日期：2006-11-01 00:00:00

abstract：:Transient receptor potential channels and cannabinoid receptors are deputed to the regulation of sensory, homeostatic, and inflammatory events in the human organism. Therefore, their modulation promises to have relevant applications in important therapeutic areas such as inflammation, pain, and cancer. This review sum...

journal_title：Planta medica

authors： Rigano D,Formisano C,Taglialatela-Scafati O

更新日期：2016-06-01 00:00:00

abstract：:Plumbagin, an active principle from Plumbaginaceous plants, produced a triphasic inotropic response (first positive, second negative, and third positive phases) in guinea-pig papillary muscle. The inotropic potency of plumbagin at the first positive phase was pD2 6.40, and the methylation of 5-hydroxy group of plumbag...

journal_title：Planta medica

authors： Itoigawa M,Takeya K,Furukawa H

更新日期：1991-08-01 00:00:00

abstract：:From the rhizomes of HYPOXIS OBTUSA two monoglucosides having the same aglycone as hypoxoside, 1-(3',4'- dihydroxyphenyl)-5-(3'',4''-dihydroxyphenyl)-1-pen-ten-4-yne, have been obtained. By methylation followed by hydrogenation they have been transformed into the same compound, 1-(3'-methoxy-4'- O-beta- D-glucopyranos...

journal_title：Planta medica

authors： Galeffi C,Multari G,De Vicente Y,Messana I,Nicoletti M,Marini-Bettolo GB

更新日期：1989-06-01 00:00:00

abstract：:The major alkaloids of PAPAVER TRINIIFOLIUM collected in two different parts of Anatolia have proved to be of the aporphine, morphinane and rhoeadine types. The two collections possessed different major alkaloids and the existence of chemical strains is indicated. In addition to the aporphine-(floripavidine), the morp...

journal_title：Planta medica

authors： Sariyar G

更新日期：1983-09-01 00:00:00

abstract：:Many compounds of plant origin have been identified that inhibit different stages in the replication cycle of human immunodeficiency virus (HIV): 1) virus adsorption: chromone alkaloids (schumannificine), isoquinoline alkaloids (michellamines), sulphated polysaccharides and polyphenolics, flavonoids, coumarins (glycoc...

journal_title：Planta medica

authors： Vlietinck AJ,De Bruyne T,Apers S,Pieters LA

更新日期：1998-03-01 00:00:00

abstract：:An efficient in vitro propagation protocol for rapidly producing Cannabis sativa plantlets from young leaf tissue was developed. Using gas chromatography-flame ionization detection (GC-FID), high THC yielding elite female clone of a drug-type CANNABIS variety (MX) was screened and its vegetatively propagated clones we...

journal_title：Planta medica

authors： Lata H,Chandra S,Khan IA,Elsohly MA

更新日期：2010-10-01 00:00:00

abstract：:HPLC determinations of the aescin contents in calli and embryoids from leaf explants of AESCULUS HIPPOCASTANUM L. were carried out in order to determine whether it was possible to obtain aescin-forming proliferations IN VITRO. The results indicate that embryogenic calli and embryoids derived from them produce an amoun...

journal_title：Planta medica

authors： Profumo P,Caviglia AM,Gastaldo P,Dameri RM

更新日期：1991-02-01 00:00:00

abstract：:The nor-kaurane diterpene Atractyliretin was obtained by acid hydrolysis of Atractyloside, a toxic substance isolated from ATRACTYLIS GUMMIFERA L (Compositae). On the basis of spectral (IR, (1)H-NMR, (13)C-NMR and MS) analysis and chemical degradation its structure and stereochemistry was identified as 4. ...

journal_title：Planta medica

authors： Camarda L,Ceraulo L,Ferrugia M,Pascual C,Sprio V

更新日期：1986-10-01 00:00:00

abstract：:The tertiary and quaternary alkaloids isolated from the stem bark, root bark and seeds of Peschiera fuchsiaefolia are reported. The tertiary alkaloid crude extract from the stem bark was tested in vitro against Plasmodium falciparum on the basis of the antimalarial use of the plant. It showed good activity against bot...

journal_title：Planta medica

authors： Federici E,Palazzino G,Nicoletti M,Galeffi C

更新日期：2000-02-01 00:00:00

abstract：:In a medium throughput screen of 880 plant and fungal extracts for antiprotozoal activity, a dichloromethane extract of Salvia miltiorrhiza roots was active against both Trypanosoma brucei rhodesiense and Plasmodium falciparum. With HPLC-based activity profiling in combination with on- and off-line spectroscopic metho...

journal_title：Planta medica

authors： Slusarczyk S,Zimmermann S,Kaiser M,Matkowski A,Hamburger M,Adams M

更新日期：2011-09-01 00:00:00

abstract：:Three new depsidones, parmosidones F - G (1 - 2), and 8'-O-methylsalazinic acid (3), and 3 new diphenylethers, parmetherines A - C (4 - 6), together with 2 known congeners were isolated from the whole thalli of Parmotrema dilatatum, a foliose chlorolichen. Their structures were unambiguously determined by extensive sp...

journal_title：Planta medica

authors： Devi AP,Duong TH,Ferron S,Beniddir MA,Dinh MH,Nguyen VK,Pham NK,Mac DH,Boustie J,Chavasiri W,Pogam PL

更新日期：2020-11-01 00:00:00

abstract：:Micellar electrokinetic capillary chromatography (MECC), using a phosphate buffer pH 7.0 and sodium dodecyl sulfate as the surfactant, was found suitable for the separation of structurally similar flavan-3-ols and related dimeric proanthocyanidins. A total of 20 substances has been tested, 17 of which were successfull...

journal_title：Planta medica

authors： Kreimeyer J,Petereit F,Nahrstedt A

更新日期：1998-02-01 00:00:00

abstract：:The concentrations of taxol and related compounds in the bark and needles of Taxus cuspidata grown on Mt. Jiri, Mt. Sobaek, and Cheju Island, and T. cuspidata var. latifolia on Ullung Island in Korea were determined by high performance liquid chromatography (HPLC). The taxane content significantly varied with the loca...

journal_title：Planta medica

authors： Choi MS,Kwak SS,Liu JR,Park YG,Lee MK,An NH

更新日期：1995-06-01 00:00:00

abstract：:Four p-terphenyl derivatives named curtisians I-L (1-4) were isolated from the MeOH extract of the fruit bodies of Paxillus curtisii. Their structures were elucidated by 2D NMR, MS, IR and UV spectroscopy and chemical reaction. The absolute configurations of curtisians were determined by GC-MS on a chiral column of th...

journal_title：Planta medica

authors： Quang DN,Hashimoto T,Nukada M,Yamamoto I,Tanaka M,Asakawa Y

更新日期：2003-11-01 00:00:00

abstract：:Cordatolide A and B were re-isolated from Calophyllum cordato-oblongum, an endemic species of Sri Lanka, and found to inhibit HIV-1 reverse transcriptase with IC50 values of 12.3 and 19.0 microM, respectively. ...

journal_title：Planta medica

authors： Dharmaratne HR,Wanigasekera WM,Mata-Greenwood E,Pezzuto JM

更新日期：1998-06-01 00:00:00

abstract：:Sponges are a useful source of bioactive natural products. Members of the family Mycalidae, in particular, have provided a variety of chemical structures including alkaloids, polyketides, terpene endoperoxides, peptides, and lipids. This review highlights the compounds isolated from Mycalid sponges and their associate...

journal_title：Planta medica

authors： Habener LJ,Hooper JN,Carroll AR

更新日期：2016-06-01 00:00:00

abstract：:The cytotoxicity and immunosuppressive activities of jaborosalactone-L and three 16 alpha-oxygenated withanolides from the leaves of Discopodium penninervium were studied. Jaborosalactone-L showed cytotoxicity only to the murine macrophage cell line, RAW 264.7, but the 16 alpha-oxygenated withanolides exhibited cytoto...

journal_title：Planta medica

authors： Habtemariam S

更新日期：1997-02-01 00:00:00

abstract：:Kava (Piper methysticum) is an effective anxiolytic that has been withdrawn from various consumer markets in European countries due to concerns over its hepatotoxicity. It is plausible that the reported hepatotoxicity may be due in part to plant substitution, or an incorrect cultivar, or plant parts being used (such a...

journal_title：Planta medica

authors： Sarris J,Teschke R,Stough C,Scholey A,Schweitzer I

更新日期：2011-01-01 00:00:00

abstract：:Qianhu, the dried roots of Peucedanum praeruptorum, is a well-known traditional Chinese medicinal herb which was officially listed in the Chinese Pharmacopoeia. Praeruptorin A is the major active constituent of Qianhu. Our previous studies show that praeruptorin effectively transactivated the protein expression and ca...

journal_title：Planta medica

authors： Huang L,Bi HC,Li YH,Zhang JQ,Kuang SY,Zhang L,Wang YT,Huang M

更新日期：2013-11-01 00:00:00

abstract：:Flavonoids are metabolized in vivo to monocyclic phenolic acids. We investigated whether 18 phenolic acids of the benzoic, phenylacetic, phenylpropanoic or cinnamic series-known or potential metabolites of flavonoids-inhibit reactive oxygen species (ROS) released by human polymorphonuclear neutrophils (PMNs). Chemilum...

journal_title：Planta medica

authors： Limasset B,Ojasoo T,le Doucen C,Doré JC

更新日期：1999-02-01 00:00:00

abstract：:This Paper describes an improved HPLC method for the determination of pentacyclic oxindole alkaloids in Uncaria tomentosa (Cat's Claw). Six of the isomeric compounds could be baseline separated at room temperature within less than 30 min by using 3 microm C-18 column material and a mobile phase consisting of 10 mM pho...

journal_title：Planta medica

authors： Ganzera M,Muhammad I,Khan RA,Khan IA

更新日期：2001-07-01 00:00:00

abstract：:For quantitative determination of grayanotoxin I (1) in plant material, a GC/MS method was developed after trimethylsilyl derivatisation of the analytes. Forskolin (5) was used as an internal standard for quantification. ICH-compliant method validation indicated sufficient specificity, precision, quantitation (15 µg/m...

journal_title：Planta medica

authors： Lechtenberg M,Dierks F,Sendker J,Louis A,Schepker H,Hensel A

更新日期：2014-10-01 00:00:00

abstract：:Blue cohosh, Caulophyllum thalictroides (L.) Michx. is a popular herb, roots and rhizomes of which have been extensively used for women's health. Alkaloids and saponins are considered to be responsible for its pharmacological effects. In this investigation the methanolic extract of the roots of blue cohosh, the alkalo...

journal_title：Planta medica

authors： Madgula VL,Ali Z,Smillie T,Khan IA,Walker LA,Khan SI

更新日期：2009-03-01 00:00:00

abstract：:Ganoderma is a genus of medicinal mushroom traditionally used for treating various diseases. Ganoderic acid A is one of the major bioactive Ganoderma triterpenoids isolated from Ganoderma species. Herein, we produced a highly specific monoclonal antibody against ganoderic acid A (MAb 12 A) and developed an indirect co...

journal_title：Planta medica

authors： Sakamoto S,Kohno T,Shimizu K,Tanaka H,Morimoto S

更新日期：2016-05-01 00:00:00

abstract：:Healing of predominantly metaphyseal fractures in postmenopausal osteoporosis is delayed and comparatively poor. Hormone replacement therapy could improve fracture healing, but, because of its potential side effects, natural alternatives are more appealing. The aim of this study was to determine if the soy metabolite ...

journal_title：Planta medica

authors： Kolios L,Sehmisch S,Daub F,Rack T,Tezval M,Stuermer KM,Stuermer EK

更新日期：2009-04-01 00:00:00

abstract：:A new isoprenylated xanthone, cudrafrutixanthone A, was isolated from the roots of Cudrania fruticosa, together with 18 known compounds. Their structures were elucidated by spectroscopic methods. Most isoprenylated xanthones exhibited cytotoxicity against HCT-116, SMMC-7721, SGC-7901, and BGC-823 cell lines with IC (5...

journal_title：Planta medica

authors： Wang YH,Hou AJ,Zhu GF,Chen DF,Sun HD

更新日期：2005-03-01 00:00:00

abstract：:Two new secodammarane triterpenoid saponins were isolated from the leaves of Cyclocarya paliurus. Based on chemical and spectral analysis they were assigned as (20S)-20-hydroxy-24-O-alpha-L-arabino-pyranosyl-3,4- secodammar-4(28),11,25-trien-3-oic acid, named cyclocarioside II and 25-hydroxy-(20S,24R)-epoxy-12R-O-beta...

journal_title：Planta medica

authors： Shu RG,Xu CR,Li LN,Yu ZL

更新日期：1995-12-01 00:00:00

abstract：:The cytotoxicity of goniothalamin was found to be strong towards both cancerous (HGC-27, MCF-7, PANC-1, HeLa), and non-cancerous (3T3) cell lines, especially in cases of dividing cells. Drug exposure studies indicated that the cytotoxic action of goniothalamin was time- and dose-dependent. At the ultrastructural level...

journal_title：Planta medica

authors： Ali AM,Mackeen MM,Hamid M,Aun QB,Zauyah Y,Azimahtol HL,Kawazu K

更新日期：1997-02-01 00:00:00

abstract：:Vitex agnus-castus, the chaste tree, is used against disorders of the female sexual organs and as an anaphrodisiac. Active constituents are not known. In this study the essential oil of the fruits was investigated by GC and GC-MS. ...

journal_title：Planta medica

authors： Zwaving JH,Bos R

更新日期：1996-02-01 00:00:00