Dysoxydensins A-G, seven new clerodane diterpenoids from Dysoxylum densiflorum.

abstract：:Comparative study of the seeds of two Cucurbitaceae Momordica charantia L. and Herpetospermum caudigerum Wall. shows and important difference for their metabolism concerning particularly aspartic acid. Momordica can produce vicin, while for Herpetospermum, this amino acid would give asparagin. In the other hand, betwe...

journal_title：Planta medica

authors： Barron D,Kaouadji M,Mariotte AM

更新日期：1982-11-01 00:00:00

abstract：:From the fresh rhizomes of Tamus communis five phenanthrenes (1 - 5) were isolated under the guidance of cytotoxic assays in HeLa cells. The compounds were obtained from the highly active CHCl (3) fraction of the MeOH extract by using multistep chromatographic purifications, including VLC, preparative TLC, HPLC and ge...

journal_title：Planta medica

authors： Réthy B,Kovács A,Zupkó I,Forgo P,Vasas A,Falkay G,Hohmann J

更新日期：2006-06-01 00:00:00

abstract：:Plumbagin, an active principle from Plumbaginaceous plants, produced a triphasic inotropic response (first positive, second negative, and third positive phases) in guinea-pig papillary muscle. The inotropic potency of plumbagin at the first positive phase was pD2 6.40, and the methylation of 5-hydroxy group of plumbag...

journal_title：Planta medica

authors： Itoigawa M,Takeya K,Furukawa H

更新日期：1991-08-01 00:00:00

abstract：:A gas-chromatographical method is described on which seven pyrrolizidine alkaloids (Fuchsisenecionine, Senecionine, Senecivernine, Senkirkine, Retrorsine, O (7)-Angelylheliotridine and Heliotrine) are determinated in a qualitative way and their ratio of concentration in Senecio fuchsii, vernalis, inaequidens and ovire...

journal_title：Planta medica

authors： Wiedenfeld H,Pastewka U,Stengl P,Röder E

更新日期：1981-02-01 00:00:00

abstract：:The random amplified polymorphic DNA analysis (RAPD) is a method to study genetic variability within and between populations and species on the basis of the amplification of anonymous fragments from genomic DNA templates by means of polymerase chain reaction (PCR). We applied RAPD analysis in order to distinguish medi...

journal_title：Planta medica

authors： Wolf HT,van den Berg T,Czygan FC,Mosandl A,Winckler T,Zündorf I,Dingermann T

更新日期：1999-02-01 00:00:00

abstract：:Valepotriates are iridoids found in variable amounts in Valerianaceae and might be among the bioactive compounds which confer anxiolytic properties to the Valeriana species. On the other hand, unspecific cytotoxicity has also been described. Presently, however, no particular molecular target has been defined for these...

journal_title：Planta medica

authors： Bettero GM,Salles L,Rosário Figueira RM,Poser Gv,Rates SM,Noël F,Quintas LE

更新日期：2011-10-01 00:00:00

abstract：:Owing to their high content of flavonoids and saponins, plantlets of Avena sativa L. (Poaceae) are likely to possess anti-inflammatory and immunoregulatory properties of value in the treatment of atopic dermatitis (AD). With a view to its potential use in atopic subjects at risk of developing sensitisation to dietary ...

journal_title：Planta medica

authors： Mandeau A,Aries MF,Boé JF,Brenk M,Crebassa-Trigueros V,Vaissière C,Teysseyre V,Bieber T

更新日期：2011-06-01 00:00:00

abstract：:Hot water extract (ALR-0) of rhizomes of Atractylodes lanceo DC. was fractionated into MeOH-soluble fraction (ALR-1), supernatant fraction of EtOH precipitation (ALR-3 + 4), and crude polysaccharide fraction (ALR-5). Among these fractions, only ALR-5 showed potent stimulating activity for proliferation of bone marrow ...

journal_title：Planta medica

authors： Yu KW,Kiyohara H,Matsumoto T,Yang HC,Yamada H

更新日期：1998-12-01 00:00:00

abstract：:A pyrolytic gaschromatographic process was developed for the routine assay of both cyclodextrin inclusion complexes, and for the differentiation of the mechanical mixture of the same oil with beta-cyclodextrin. The method is a direct assay of low material demand. ...

journal_title：Planta medica

authors： Pobozsny K,Kernóczi L,Tétényi P,Héthelyi I,Szejtli J

更新日期：1981-07-01 00:00:00

abstract：:Flavonolignan compounds have been isolated from the fruits of SILYBUM MARIANUM subsp. ANATOLICUM and kaempferol 3-sulphate and other flavonoid compounds have been isolated from the aerial parts and were identified. The flavonoid sulphate derivatives are shown to be present in SILYBUM genus for the first time. ...

journal_title：Planta medica

authors： Meriçli AH

更新日期：1988-02-01 00:00:00

abstract：:Ginkgetin, a biflavone isolated from Ginkgo biloba leaves, was previously reported as an inhibitor of group II phospholipase A2. In this study, ginkgetin was evaluated for in vivo antiarthritic and analgesic activities. Ginkgetin (10-20 mg/kg/day) strongly reduced arthritic inflammation in an animal model of rat adjuv...

journal_title：Planta medica

authors： Kim HK,Son KH,Chang HW,Kang SS,Kim HP

更新日期：1999-06-01 00:00:00

abstract：:ECa 233, a standardized extract of Centella asiatica, has been found to exhibit various positive neurological effects and to have a good safety profile. The present study aimed to explore the disposition kinetics of ECa 233, containing madecassoside (53.1 %) and asiaticoside (32.3 %), in rats. The extract was intraven...

journal_title：Planta medica

authors： Anukunwithaya T,Tantisira MH,Tantisira B,Khemawoot P

更新日期：2017-05-01 00:00:00

abstract：:Sesquiterpene lactones 1-5 were isolated for the first time from the ethyl acetate of Vernonia fastigiata (Asteraceae). Compounds 3, 4 and 5 are new, compounds 1 and 2 have been found earlier in other Vernonia species but not in V. fastigiata. ...

journal_title：Planta medica

authors： Roos G,Prawat H,Walter CU,Klaiber I,Vogler B,Guse JH,Kraus W

更新日期：1998-10-01 00:00:00

abstract：:A systematic structure-activity relationship of 3beta-hydroxy-27- P- E-coumaroyloxyurs-12-en-28-oic acid ( 7), a triterpene ester isolated from UNCARIA RHYNCHOPHYLLA as a phospholipase Cgamma1 inhibitor, was undertaken with a view toward elucidating its chemical mode of action on PLCgamma1. Related derivatives and ana...

journal_title：Planta medica

authors： Lee JS,Yoo H,Suh YG,Jung JK,Kim J

更新日期：2008-10-01 00:00:00

abstract：:From an extract of the whole plant of Ligularia virgaurea ssp. oligocephala, three new eremophilane sesquiterpene lactones, 10alpha-hydroxy-1-oxoeremophila-7(11),8(9)-dien-12,8-olide (1), 6alpha,10alpha-dihydroxy-1-oxoeremophila-7(11),8(9)-dien-12,8-olide (2), 6beta,10beta-dihydroxyeremophila-7(11),8(9)-dien-12,8-olid...

journal_title：Planta medica

authors： Wu QX,Shi YP,Yang L

更新日期：2004-05-01 00:00:00

abstract：:Evodiamine, a major alkaloidal principle of Evodia fruits (Evodia rutaecarpa, Rutaceae), showed vanilloid receptor agonistic activities comparable to capsaicin. The Chinese literature refers to Evodia fruits as a "hot nature" herb. In spite of the similarities in the actions of evodiamine and capsaicin in vitro, evodi...

journal_title：Planta medica

authors： Kobayashi Y,Nakano Y,Kizaki M,Hoshikuma K,Yokoo Y,Kamiya T

更新日期：2001-10-01 00:00:00

abstract：:Five compounds representative of major structural classes of lichen polyketides, VIZ. (+)-usnic (1), salazinic (2), vulpinic (3), gyrophoric (4), and evernic acids (5), were investigated for their ability to affect cell proliferation or wound healing, two functional targets of relevance for research on cancer or tissu...

journal_title：Planta medica

authors： Burlando B,Ranzato E,Volante A,Appendino G,Pollastro F,Verotta L

更新日期：2009-05-01 00:00:00

abstract：:Barbaloin levels in the exudates from the leaves of 68 species of ALOE in the Kew collection have been determined by light absorption at 375 nm following separation by HPLC. The exudates from most species contained between 10-20% although a few concentrations of around 30% were found. The level in the leaf was usually...

journal_title：Planta medica

authors： Groom QJ,Reynolds T

更新日期：1987-08-01 00:00:00

abstract：:In the present study, we examined the effects of deoxyschisandrin (DS) from Schisandra chinensis on the amyloid-beta₁₋₄₂ (Aβ₁₋₄₂)-induced memory impairment in mice and investigated the possible antioxidative mechanism. Mice were given an intracerebroventricular (i. c. v.) injection with the aggregated Aβ₁₋₄₂ and then ...

journal_title：Planta medica

authors： Hu D,Li C,Han N,Miao L,Wang D,Liu Z,Wang H,Yin J

更新日期：2012-08-01 00:00:00

abstract：:A simple and efficient method for the separation of the three phenolic diketones, curcumin 1, demethoxycurcumin 2, and bis-demethoxycurcumin 3, isolated from the rhizomes of Curcuma longa has been developed. The method is of general applicability for the separation of compounds containing acidic and chelating groups a...

journal_title：Planta medica

authors： Rasmussen HB,Christensen SB,Kvist LP,Karazmi A

更新日期：2000-05-01 00:00:00

abstract：:We present the application of the generative topographic map algorithm to visualize the chemical space populated by natural products and synthetic drugs. Generative topographic maps may be used for nonlinear dimensionality reduction and probabilistic modeling. For compound mapping, we represented the molecules by two-...

journal_title：Planta medica

authors： Miyao T,Reker D,Schneider P,Funatsu K,Schneider G

更新日期：2015-04-01 00:00:00

abstract：:Diabetes mellitus is one of the major health problems in Africa. The conventional oral synthetic antidiabetic drugs available to manage the disease are costly and not readily affordable to the majority of the affected population. Interestingly, the continent is endowed with a tremendous number of medicinal plants that...

journal_title：Planta medica

authors： Mohammed A,Ibrahim MA,Islam MS

更新日期：2014-03-01 00:00:00

abstract：:The inhibitory effect of flavonoids and phenolic acids, which could be transformed from flavonoids by human intestinal microflora, on the growth of Helicobacter pylori (HP) was investigated. Ponciretin, hesperetin, naringenin and diosmetin were active against HP. Among them, ponciretin was the most potent and its MIC ...

journal_title：Planta medica

authors： Bae EA,Han MJ,Kim DH

更新日期：1999-06-01 00:00:00

abstract：:N-Deacetylcolchiceine (DAC) administered i.p. to rats decreased the level of serum cholesterol and apoB. It was accompanied by the fall of HDL-C due to the decrease of both HDL subfractions HDLa and HDLb, and by a rather weaker decrease of LDL-C. The levels of serum and lipoprotein triacylglycerols were not significan...

journal_title：Planta medica

authors： Skottová N,Vecera R,Walterová D,Simánek V

更新日期：1992-02-01 00:00:00

abstract：:A new BIS-1-oxaquinolizidine alkaloid, 9'- EPI-3 β,3' β-dimethylxestospongin C (2), and three known related analogues have been isolated from the Hainan sponge Neopetrosia exigua. ...

journal_title：Planta medica

authors： Li Y,Qin S,Guo YW,Gu YC,van Soest RW

更新日期：2011-01-01 00:00:00

abstract：:Seven phenolic derivatives, 2,4-bis(4-hydroxybenzyl)phenol ( 1), bis[4(beta- D-glucopyranosyloxy)-benzyl] ( S)-(-)-2-isopropylmalate ( 2), bis[4-(beta- D-gluco-pyranosyloxy)benzyl] ( S)-(-)-2-sec-butylmalate ( 3), 4-hydroxybenzyaldehyde ( 4), 4,4'-dihydroxydiphenyl-methane ( 5), 4-hydroxybenzyl alcohol ( 6), and 4-(be...

journal_title：Planta medica

authors： Yi-Ming L,Zhuo-Lun Z,Yong-Fu H

更新日期：1993-08-01 00:00:00

abstract：:Bioactivity-guided fractionation of Saururus chinensis (Saururaceae) using a lymphoproliferation assay led us to isolate 5 lignans (compounds 1 - 5). Compounds 1 - 5 were identified as sauchinone, (-)-saucerneol, saucerneol C, manassantin A, and manassantin B, respectively, by spectroscopic analyses. The immunosuppres...

journal_title：Planta medica

authors： Park SY,Lee SH,Choi WH,Koh EM,Seo JH,Ryu SY,Kim YS,Kwon DY,Koh WS

更新日期：2007-06-01 00:00:00

abstract：:Flavonoids are metabolized in vivo to monocyclic phenolic acids. We investigated whether 18 phenolic acids of the benzoic, phenylacetic, phenylpropanoic or cinnamic series-known or potential metabolites of flavonoids-inhibit reactive oxygen species (ROS) released by human polymorphonuclear neutrophils (PMNs). Chemilum...

journal_title：Planta medica

authors： Limasset B,Ojasoo T,le Doucen C,Doré JC

更新日期：1999-02-01 00:00:00

abstract：:Verbascoside is a phenylethanoid glycoside widely distributed in nature, especially among the order Lamiales, occurring in numerous plants that are constituents of folk medicine preparations. This natural compound, previously isolated by our group from the ethyl acetate extract of Lantana trifolia using the gradient a...

journal_title：Planta medica

authors： Leitão GG,Pinto SC,de Oliveira DR,Timoteo P,Guimarães MG,Cordova WH,Leitão SG

更新日期：2015-11-01 00:00:00

abstract：:A new resveratrol dimer, (+)-vitisinol E (1) which demonstrated inhibitory activity on BACE-1 (beta-site APP-cleaving enzyme 1) in vitro, was isolated from the stembark extract of Vitis vinifera (Vitaceae) together with four known resveratrol oligomers, (+)-epsilon-viniferin (2), (+)-ampelopsin A (3), (+)-vitisin A (4...

journal_title：Planta medica

authors： Choi YH,Yoo MY,Choi CW,Cha MR,Yon GH,Kwon DY,Kim YS,Park WK,Ryu SY

更新日期：2009-04-01 00:00:00