Abstract:
:From the roots of Aconitum crassicaule, two new diterpenoid alkaloids, crassicaulisine and crassicaulidine, were isolated. The structure of crassicaulisine, C (24)H (39)O (7)N, has been elucidated as 3 on the basis of chemical and spectral data, while the structure of crassicaulidine, C (24)H (39)O (8)N, has been shown as 4 on the basis of chemical data and spectral comparison with crassicaulisine.
journal_name
Planta Medjournal_title
Planta medicaauthors
Fengpeng W,Qicheng Fdoi
10.1055/s-2007-969945subject
Has Abstractpub_date
1983-01-01 00:00:00pages
39-42issue
1eissn
0032-0943issn
1439-0221journal_volume
47pub_type
杂志文章相关文献
PLANTA MEDICA文献大全abstract::Two new compounds, methyl 3-chloro-6-hydroxy-2-(4-hydroxy-2-methoxy-6-methylphenoxy)-4-methoxybenzoate (1) and (2 S,5' R,E)-7-hydroxy-4,6-dimethoxy-2-(1-methoxy-3-oxo-5-methylhex-1-enyl)-benzofuran-3(2H)-one (2), together with four known compounds, griseofulvin (3), dechlorogriseofulvin (4), bostrycin (5), and deoxybo...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1271040
更新日期:2011-10-01 00:00:00
abstract::Phytoestrogens are discussed as candidate substances to treat symptoms related to estrogen deficiency. In in vitro experiments, the naturally occurring flavonoid 6-(1,1-dimethylallyl)naringenin (6-DMAN) emerged as one of the most potent phytoestrogenic substances. 6-DMAN is not as well characterized as other flavonoid...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2004-827178
更新日期:2004-07-01 00:00:00
abstract::Three new compounds, 15-acetoxy-12-hydroxy-16-methyl-labda-8(17),13E-diene (1), ent-labda-8(17),13-dien-15,16-olid-19-oic acid methyl ester (2), and 12-hydroxy-labda-8(17),13-dien-15,16-olide (3), together with two known compounds, 19-acetoxy-ent-labda-8(17),13-dien-15,16-olide (4), and 16-acetoxy-12,15-epoxy-15beta-h...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-967170
更新日期:2007-05-01 00:00:00
abstract::Human vascular endothelial cells (HUVECs) were exposed to CoCl2 as an in vitro model of hypoxia. Expression of VCAM-1 (vascular cell adhesion molecule), reduction of PECAM-1 (platelet endothelial cell adhesion molecule) and cytoskeletal changes without alterations in cell viability were observed. HUVECs were also expo...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-967118
更新日期:2007-03-01 00:00:00
abstract::The reactions of chloranil, fluoranil, 2,5 dichlorobenzoquinone and chloranilic acid with some alkaloids on thin layer chromatograms were examined with a view to determine their suitability as visualizing agents. Chloranil and 2,5 dichlorobenzoquinone (each 0.5% w/v in dioxan) were found to be most suitable as they ga...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-971381
更新日期:1982-08-01 00:00:00
abstract::A reinvestigation of the aerial parts of TEUCRIUM SCORDIUM afforded in addition to several known diterpenes five new clerodane derivatives, all closely related to teucrin. The structures and the stereochemistry were elucidated by high resolution (1)H-NMR spectroscopy. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969508
更新日期:1985-08-01 00:00:00
abstract::The absolute stereostructure of a novel skeletal diterpene, standishinal (1), from the bark of Thuja standishii was confirmed by X-ray crystallographic analyses of 1 and its p-bromobenzoate derivative. Aromatase inhibitory activities of standishinal, eight known diterpenes, totarol, 12-methoxyabieta-8,11,13-trien-11-o...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-33787
更新日期:2002-08-01 00:00:00
abstract::Fresh Nagami kumquats (Fortunella margarita) were subjected to hydrodistillation using a Clevenger-type apparatus to obtain volatile oil. The chemical composition of the volatile oil was analyzed by GC-MS using Rtx-5 Sil MS and DB Wax columns. A total of 25 volatile compounds were identified by mass spectra, retention...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0031-1298619
更新日期:2012-06-01 00:00:00
abstract::We aimed to find antiallergic agents from natural sources using mast cells activated during allergic reaction. We screened over 2000 plants for blockade of histamine release and identified two of them, S. baicalenesis and P. edulis. Bioassay-guided fractionation led to two main constituent flavonoids, baicalin from S....
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1240649
更新日期:2010-05-01 00:00:00
abstract::Five new dibenzocyclooctane lignans, schisanwilsonins K-O, together with eighteen known lignans were isolated from the stems of Schisandra wilsoniana. The structures of these new compounds were elucidated by spectroscopic methods, including 2D-NMR techniques. Several compounds were found to show anti-HIV and anti-HBV ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1328747
更新日期:2013-08-01 00:00:00
abstract::During activity-guided fractionations to screen for antineoplastic agents, further studies by means of preparative HPLC led to the isolation of four known furostanol saponins: protoneodioscin, protodioscin, protoneogracillin, protogracillin, along with their corresponding artifacts: methyl protoneodioscin, methyl prot...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957636
更新日期:1997-04-01 00:00:00
abstract::Amyloid-β, one of the hallmarks of Alzheimer's disease, is toxic to neurons and causes cell death in the brain. Oxidative stress is known to play an important role in Alzheimer's disease, and there is strong evidence linking oxidative stress to amyloid-β. The herbal plant "Tiew kon" (Cratoxylum formosum ssp. pruniflor...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0041-111621
更新日期:2016-04-01 00:00:00
abstract::The ether fraction of the defatted ethanol extract of the aerial parts of Caralluma penicillata (defl) M. E. Br. (Asclepiadaceae) yielded four new oxypregnane glycosides, penicillosides D-G. The structures of the isolated compounds were established by different spectroscopic methods. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-32078
更新日期:2002-05-01 00:00:00
abstract::A microdilution technique was developed for the assessment of in vitro cytotoxicity against KB cells derived from a human epidermoid carcinoma of the nasopharynx. The test was used to determine the cytotoxicity of a series of quassinoids, isolated from Brucea javanica, and which have previously been shown to demonstra...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960020
更新日期:1991-02-01 00:00:00
abstract::Two new 8-oxotetrahydroprotoberberine alkaloids, gusanlung A(1) and B(2), together with known isoquinoline alkaloids, berberine and jatrorrhizine, were isolated from the Chinese medicinal plant Acangelisia gusanlung H. S. Lo (Menispermaceae). Their structures were elucidated mainly by spectroscopic analysis. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960150
更新日期:1991-10-01 00:00:00
abstract::Chemical investigation of the EtOH extract of Morus alba L. (Moraceae), as guided by free radical scavenging activity, furnished 5,7-dihydroxycoumarin 7-methyl ether (1), two prenylflavones, cudraflavone B (2) and cudraflavone C (3), and oxyresveratrol (4). Compounds 1 and 4 showed superoxide scavenging effects with t...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-34930
更新日期:2002-10-01 00:00:00
abstract::Treatment of 28-hydroxyolean-12-enes with N-bromosuccinimide (NBS) in acetonitrile at room temperature afforded 12 alpha-bromooleanan-13beta, 28-epoxides in high yield. This reaction resulted in the formation of olean-9 (11), 12-diene-18alpha, 29-epoxides from 29-hydroxy isomers but recovered only starting materials f...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969575
更新日期:1985-12-01 00:00:00
abstract::Hydroalcoholic extracts and pressed juice from Echinacea pallida were phytochemically characterised by HPLC-MS analyses. Ferulic and caffeic acid derivatives were identified as major constituents. All tested extracts and pressed juice from Echinacea pallida exhibited a low cytotoxic activity on monkey kidney cells in ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1186137
更新日期:2010-02-01 00:00:00
abstract::The Mexican species GALPHIMIA GLAUCA (Cav.) Kuntze (Malphigiaceae) synthesises a family of sedative and anxiolytic nor-secofriedelanes, designated as galphimines. These active principles accumulate at low concentration in the aerial parts of plants from wild populations. Transformed calluses and cell suspension cultur...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1186166
更新日期:2010-03-01 00:00:00
abstract::Bioactivity-directed separation led to the identification of four compounds, viz. denbinobin (1), 3,7-dihydroxy-2,4-dimethoxyphenanthrene (2), 3-methylgigantol (3), and erianthridin (4) from the ethanolic extract of Ephemerantha lonchophylla. Antiplatelet tests were carried out using 4 different aggregation inducers, ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2000-8553
更新日期:2000-05-01 00:00:00
abstract::Lipophilic extracts of Isatis tinctoria L. exhibit significant activity against several clinically relevant targets of inflammation. The alkaloid tryptanthrin was identified as one of the active principles in woad and characterised as a potent dual inhibitor of COX-2 and 5-LOX. Here, the anti-inflammatory efficacy of ...
journal_title:Planta medica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2004-818963
更新日期:2004-05-01 00:00:00
abstract::Echinacea purpurea cell cultures have been established for the production of secondary and possibly bioactive compounds using elicitation techniques. Different elicitors including yeast elicitor, methyl jasmonate, glutathione, and manganese ions were used and compared for their effects on the formation of phenolics in...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-873201
更新日期:2006-02-01 00:00:00
abstract::A pyrolytic gaschromatographic process was developed for the routine assay of both cyclodextrin inclusion complexes, and for the differentiation of the mechanical mixture of the same oil with beta-cyclodextrin. The method is a direct assay of low material demand. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-971636
更新日期:1981-07-01 00:00:00
abstract::Positive inotropic effects induced by 6-benzylaminopurine (6-BAP), kinetin and zeatin were studied in rat atria. The potency order observed was 6-BAP > or = kinetin > zeatin. Suramin, a P2-purinoceptor antagonist, inhibited the positive effect of 6-BAP suggesting the involvement of P2-purinoceptors in the positive eff...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-1999-13987
更新日期:1999-04-01 00:00:00
abstract::An ionpair-HPLC-technic using a reversed-phase column was developed to screen plant extracts for cardiotonic amines and to isolate them in a preparative scale for direct MS and pharmacological investigations. By this method the positive inotropic tyramine could be isolated from Selenicereus grandiflorus (L.) Britt et ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-971397
更新日期:1982-01-01 00:00:00
abstract::The hydroalcoholic extract (HE) obtained from stems and leaves of Hedyosmum brasiliense, given i.p., produced significant inhibition of acetic acid-induced abdominal constriction in mice, with a mean ID50 of 12.7 mg/kg. This effect installed rapidly (0.5 h) and lasted for up to 2 h. Given orally up to 1000 mg/kg, the ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-1999-14007
更新日期:1999-08-01 00:00:00
abstract::EGFR, as a critical signaling pathway in many human tumors, has become an important target of cancer drug design. Taspine has shown meaningful angiogenesis activity in previous studies. This paper is to investigate the antitumor action of taspine by modulating the EGFR signaling pathway. The study determined the expre...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1271132
更新日期:2011-11-01 00:00:00
abstract::A known sesquiterpene lactone, encelin, isolated from the Mexican species Montanoa speciosa (Compositae), was assayed for biocidal activity on fungal cells of Mucor rouxii. The results indicate that encelin has a determining action on growth and the morphogenetic process of fungal cells. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-958046
更新日期:1995-04-01 00:00:00
abstract::Sigmoidin A (SGN) is a prenylated flavanone derivative of eriodictyol (ERD) with reported moderate antioxidant, antimicrobial and anti-inflammatory activity. Since ERD and other structurally similar antioxidant phenolic compounds have been shown to induce prooxidative macromolecular damage and cytotoxicity in cancer c...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1240604
更新日期:2010-04-01 00:00:00
abstract::One hundred and thirty-eight medicinal herbal drugs obtained from different suppliers were examined for microbial contaminants and for the detectability of pathogenic microorganisms. For this purpose, several microbiological standard parameters (total aerobic mesophilic count, enterobacteria, coliforms, aerobic sporef...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-12007
更新日期:2001-04-01 00:00:00